| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00002546
|
Inermin
/ Maackiain / (-)-Maackiain / Demethylpterocarpin / 3-Hydroxy-8,9-methylenedioxypterocarpan |
CHEMBL334918
CHEMBL239047 CHEMBL445279 |
3 / 2 / 3 | No. 66 | No. 15 |
|
||
|
C00009616
|
Pterocarpin
/ 3-Methoxy-8,9-methylenedioxypterocarpan |
CHEMBL21103
CHEMBL242128 CHEMBL1983713 |
7 / 8 / 10 | No. 66 | No. 15 |
|
||
|
C00019174
|
2-Hydroxy-4-methoxy-6-(13-hydroxy-2-oxotridecyl)benzoic acid
|
No. 8661 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P13866 | Sodium/glucose cotransporter 1 | Glucose | C00002546 C00009616 | 1 / 1 |
| P31639 | Sodium/glucose cotransporter 2 | Glucose | C00002546 C00009616 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00009616 | 4 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002546 | 0 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00009616 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00009616 | 1 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00009616 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00009616 | 1 / 4 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606824 | Glucose/galactose malabsorption; ggm |
P13866
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #233100 | Renal glucosuria; glys1 |
P31639
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01261 | Congenital glucose-galactose malabsorption (GGM) |
P13866
(related)
|
| H01126 | Familial renal glucosuria (FRG) |
P31639
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|