Species

KNApSAcK Entry

Organism name Ononis viscosa subsp. breviflora
Genus Ononis
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ononis viscosa subsp. breviflora
Linked NCBI taxonomy ID 798057
Linked level subspecies

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002546 External link 512 Inermin
/ Maackiain
/ (-)-Maackiain
/ Demethylpterocarpin
/ 3-Hydroxy-8,9-methylenedioxypterocarpan
CHEMBL334918
CHEMBL239047
CHEMBL445279
3 / 2 / 3 No. 66 No. 15
C00002547 External link 512 (-)-Medicarpin
/ 3-Hydroxy-9-methoxypterocarpan
CHEMBL238845
CHEMBL413297
C047353
3 / 1 / 1 No. 66 No. 15
C00009613 External link 512 Baphinitone
/ (-)-Homopterocarpin
/ 3,9-Dimethoxypterocarpan
CHEMBL277682
CHEMBL396671
CHEMBL2007304
No. 66 No. 15
C00009616 External link 512 Pterocarpin
/ 3-Methoxy-8,9-methylenedioxypterocarpan
CHEMBL21103
CHEMBL242128
CHEMBL1983713
7 / 8 / 10 No. 66 No. 15
C00019176 External link 512 11b-Hydroxy-1-dihydromedicarpin
CHEMBL391520
No. 2023
C00019175 External link 512 11b-Hydroxy-11b-1-dihydromaackiain
CHEMBL240715
No. 2023
C00019174 External link 512 2-Hydroxy-4-methoxy-6-(13-hydroxy-2-oxotridecyl)benzoic acid
No. 8661

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P13866 Sodium/glucose cotransporter 1 Glucose C00002546 C00009616 1 / 1
P31639 Sodium/glucose cotransporter 2 Glucose C00002546 C00009616 1 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00009616 4 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00009616 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002546 0 / 1
O75496 Geminin Unclassified protein C00002547 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002547 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00009616 1 / 1
Q13951 Core-binding factor subunit beta Unclassified protein C00009616 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00009616 1 / 4
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002547 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#600274 Frontotemporal dementia; ftd P10636
#606824 Glucose/galactose malabsorption; ggm P13866
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#233100 Renal glucosuria; glys1 P31639
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (11)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01261 Congenital glucose-galactose malabsorption (GGM) P13866 (related)
H01126 Familial renal glucosuria (FRG) P31639 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)