PCIDB

KNApSAcK Metabolite C00003800

Metabolite

KNApSAcK Entry

id C00003800
Name 7,4'-Dihydroxyflavone
CAS RN 2196-14-7
Standard InChI InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-8,16-17H
Standard InChI (Main Layer) InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-8,16-17H

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 76

Link

ChEMBL

By standard InChI CHEMBL294878
By standard InChI Main Layer CHEMBL294878

KEGG

By LinkDB C12123

CTD

By CAS RN C085172

Species

Summary

Plant class

class name count
rosids 47

Family

family name count
Fabaceae 47

List (47)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Baptisia arachnifera 49796 Fabaceae rosids Viridiplantae
Baptisia australis 149633 Fabaceae rosids Viridiplantae
Baptisia bracteata 313912 Fabaceae rosids Viridiplantae
Baptisia calycosa 49796 Fabaceae rosids Viridiplantae
Baptisia cinerea 313913 Fabaceae rosids Viridiplantae
Baptisia lanceolata 49796 Fabaceae rosids Viridiplantae
Baptisia lecontei 49796 Fabaceae rosids Viridiplantae
Baptisia megacarpa 49796 Fabaceae rosids Viridiplantae
Baptisia nuttalliana 49796 Fabaceae rosids Viridiplantae
Baptisia perfoliata 49796 Fabaceae rosids Viridiplantae
Baptisia simplicifolia 49796 Fabaceae rosids Viridiplantae
Baptisia sphaerocarpa 313914 Fabaceae rosids Viridiplantae
Caesalpinia decapetala 191885 Fabaceae rosids Viridiplantae
Glycyrrhiza echinata 46348 Fabaceae rosids Viridiplantae
Glycyrrhiza glara 46347 Fabaceae rosids Viridiplantae
Glycyrrhiza pallidiflora 74859 Fabaceae rosids Viridiplantae
Medicago arabica 70936 Fabaceae rosids Viridiplantae
Medicago coronata 66811 Fabaceae rosids Viridiplantae
Medicago intertexta 70950 Fabaceae rosids Viridiplantae
Medicago laciniata 70952 Fabaceae rosids Viridiplantae
Medicago littoralis 75626 Fabaceae rosids Viridiplantae
Medicago marina 66815 Fabaceae rosids Viridiplantae
Medicago minima 70957 Fabaceae rosids Viridiplantae
Medicago monspeliaca 70959 Fabaceae rosids Viridiplantae
Medicago orbicularis 70962 Fabaceae rosids Viridiplantae
Medicago polymorpha 47084 Fabaceae rosids Viridiplantae
Medicago radiata 70968 Fabaceae rosids Viridiplantae
Medicago sativa 3879 Fabaceae rosids Viridiplantae
Medicago truncatula 3880 Fabaceae rosids Viridiplantae
Pterocarpus marsupium 1071187 Fabaceae rosids Viridiplantae
Sophora chrysophylla 171561 Fabaceae rosids Viridiplantae
Sophora microphylla 70607 Fabaceae rosids Viridiplantae
Sophora prostrata 76398 Fabaceae rosids Viridiplantae
Sophora substrata 3896 Fabaceae rosids Viridiplantae
Thermopsis macrophylla 114322 Fabaceae rosids Viridiplantae
Thermopsis mollis 49852 Fabaceae rosids Viridiplantae
Thermopsis rhombifolia 61122 Fabaceae rosids Viridiplantae
Thermopsis villosa 114325 Fabaceae rosids Viridiplantae
Trifolium repens 3899 Fabaceae rosids Viridiplantae
Trifolium subterraneum 3900 Fabaceae rosids Viridiplantae
Trigonella anguina 390135 Fabaceae rosids Viridiplantae
Trigonella coerulescens 200964 Fabaceae rosids Viridiplantae
Trigonella foenum-graecum 78534 Fabaceae rosids Viridiplantae
Trigonella laciniata 78532 Fabaceae rosids Viridiplantae
Trigonella maritima 1210111 Fabaceae rosids Viridiplantae
Trigonella spicata 119386 Fabaceae rosids Viridiplantae
Vicia faba 3906 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

17 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL294878 CHEMBL1613842 (1)
4 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL294878 CHEMBL2341203 (1) CHEMBL2341207 (1)
0 / 0
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase CHEMBL294878 CHEMBL641142 (1)
1 / 1
Q9Y3R4 Sialidase-2 Enzyme CHEMBL294878 CHEMBL1100507 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL294878 CHEMBL1614458 (1)
0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 CHEMBL294878 CHEMBL1105634 (1)
2 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL294878 CHEMBL1059360 (1) CHEMBL1059361 (1)
5 / 3
P06280 Alpha-galactosidase A Enzyme CHEMBL294878 CHEMBL1614369 (1)
1 / 1
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL294878 CHEMBL1613808 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL294878 CHEMBL1613910 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL294878 CHEMBL1614038 (1)
2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL294878 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 CHEMBL294878 CHEMBL1059364 (1) CHEMBL1059365 (1)
0 / 0
P06239 Tyrosine-protein kinase Lck Src CHEMBL294878 CHEMBL941407 (1)
0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL294878 CHEMBL1613914 (1)
0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase CHEMBL294878 CHEMBL731145 (1)
0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL294878 CHEMBL731145 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#610251 Alcohol sensitivity, acute P05091
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
%606641 Body mass index; bmi P37231
#300615 Brunner syndrome P21397
#609338 Carotid intimal medial thickness 1 P37231
#119900 Digital clubbing, isolated congenital P15428
#301500 Fabry disease P06280
#137800 Glioma susceptibility 1; glm1 P37231
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#601665 Obesity P37231
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (16)

KEGG disease name UniProt
H01071 Acute alcohol sensitivity P05091 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)