Vicia faba

• Index
• Plant Species
• Metabolite list (50)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Vicia faba
Genus	Vicia
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Vicia faba
Linked NCBI taxonomy ID	3906
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (50)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00007247	Linolenic acid / alpha-Linolenic acid / (Z,Z,Z)-Octadeca-9,12,15-trienoic acid		D017962		22 / 5
C00005981	Quercetin 3-(6''-acetylgalactoside)-7-rhamnoside					No. 1	No. 15
C00005888	Kaempferol 3-(6''-acetylgalactoside)-7-rhamnoside					No. 1	No. 15
C00005178	Kaempferol 3-galactoside-7-rhamnoside	CHEMBL1929192 CHEMBL1929193		2 / 0 / 0		No. 1	No. 15
C00005425	Quercetin 3-galactoside-7-rhamnoside	CHEMBL592361 CHEMBL1774171				No. 1	No. 15
C00005408	Quercetin 3-galactosyl-(1->6)-glucoside	CHEMBL1097317				No. 1	No. 15
C00005184	Kaempferol 3-glucoside-7-rhamnoside	CHEMBL1929192 CHEMBL1929193		2 / 0 / 0		No. 1	No. 15
C00005182	Kaempferol 3,7-diglucoside / Kaempferol 3,7-O-beta-D-diglucopyranoside	CHEMBL2206209				No. 1	No. 15
C00001071	Myricetin	CHEMBL164	C040015	78 / 70 / 56	39 / 2	No. 3	No. 15
C00005906	Kaempferol 3-rhamnosyl-(1->2)(6''-acetylgalactoside)-7-rhamnoside					No. 5	No. 15
C00005224	Kaempferol 3-rhamnosyl-(1->2)-galactoside-7-rhamnoside	CHEMBL1929027 CHEMBL1926685		2 / 0 / 0		No. 5	No. 15
C00009075	Procyanidin B1 / Epicatechin-(4beta->8)-catechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914	C479579	20 / 7 / 8		No. 16	No. 19
C00002935	Procyanidin B4 / Catechin-(4alpha->8)-epicatechin	CHEMBL38714 CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914		20 / 7 / 8		No. 16	No. 19
C00002923	Prodelphinidin B4 / Gallocatechin-(4alpha->8)-epigallocatechin	CHEMBL349509 CHEMBL161013				No. 16	No. 19
C00009111	Prodelphinidin C					No. 16	No. 19
C00009112	Gallocatechin-(4alpha->8)-epicatechin					No. 16	No. 19
C00000299	GA98 / Gibberellin A98					No. 40	No. 41
C00000020	GA20 / Gibberellin A20					No. 40	No. 41
C00000044	GA44 / Gibberellin A44					No. 40	No. 41
C00000029	GA29 / Gibberellin A29					No. 40	No. 41
C00008818	Epigallocatechin / (-)-Epigallocatechin	CHEMBL47386 CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845		26 / 17 / 29		No. 52	No. 14
C00000956	(-)-Epicatechin	CHEMBL80941 CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912		85 / 58 / 54		No. 52	No. 14
C00000181	Castasterone		C083545			No. 68	No. 11
C00000180	24-Epibrassinolide	CHEMBL563853 CHEMBL1801925 CHEMBL1967970				No. 68	No. 11
C00000189	Brassinone / Norcastasterone / 28-Norcastasterone					No. 68	No. 11
C00000192	Dolichosterone					No. 68	No. 11
C00000176	Brassinolide	CHEMBL563853 CHEMBL1801925 CHEMBL1967970	C023623		16 / 2	No. 68	No. 11
C00003825	3',4',7-Trihydroxyflavone / 7,3',4'-Trihydroxyflavone	CHEMBL301624		4 / 5 / 5		No. 71	No. 15
C00003800	7,4'-Dihydroxyflavone	CHEMBL294878	C085172	17 / 19 / 16		No. 76	No. 15
C00000019	GA19 / Gibberellin A19		C120175			No. 187	No. 41
C00000053	GA53 / Gibberellin A53					No. 187	No. 41
C00000225	9,10-Dihydrojasmonic acid					No. 707	No. 70
C00000218	Jasmonic acid / trans-Jasmonic acid / 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid	CHEMBL445499 CHEMBL449572	C011006	4 / 1 / 0		No. 707	No. 70
C00000362	OPC-6:0					No. 707	No. 70
C00000134	(s)-(+)-Abscisic acid / 2,4-Pentadienoic acid	CHEMBL288040 CHEMBL379808 CHEMBL1318134 CHEMBL1469719 CHEMBL1741460 CHEMBL1965138	D000040	10 / 9 / 10		No. 1435	No. 38
C00011540	Nigellic acid	CHEMBL396834				No. 1435	No. 38
C00001357	L-Dopa	CHEMBL1009 CHEMBL351042 CHEMBL211670		140 / 68 / 62		No. 1584
C00001145	Raffinose	CHEMBL175500 CHEMBL603717	D011887			No. 1765
C00001518	L-Glutathione	CHEMBL100476 CHEMBL1543 CHEMBL1514919	D005978	12 / 17 / 16	119 / 45	No. 3357
C00000447	4-Hydroxy-2E-nonenal	CHEMBL454280		4 / 7 / 6		No. 3536
C00001201	Quinic acid	CHEMBL444501 CHEMBL465398	D011801	5 / 1 / 3		No. 3541
C00001183	Fumaric acid	CHEMBL503160 CHEMBL539648	C032005	17 / 14 / 46	0 / 1	No. 3766
C00000103	4-Chloroindole-3-acetic acid methyl ester		C028267			No. 4225
C00000102	4-Chloro-IAA / 4-Chloroindole-3-acetic acid	CHEMBL309993	C096198	1 / 0 / 0		No. 4225
C00001515	Vicine		C009661			No. 4434
C00001299	Wyerone					No. 5575	No. 69
C00001300	Wyerone acid					No. 5575	No. 69
C00001431	Spermidine	CHEMBL19612	D013095	26 / 10 / 12	5 / 5	No. 5867
C00001432	Spermine	CHEMBL23194	D013096	35 / 17 / 25	7 / 11	No. 7197
C00001198	Oxalic acid	CHEMBL146755	D019815	2 / 0 / 0	1 / 6	No. 7540

Human Protein / Gene in interactions

255 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000134 C00000956 C00001071 C00001357 C00001431 C00001432 C00002935 C00003800 C00009075	0 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000956 C00001071 C00001357 C00001431 C00001432 C00001518 C00002935 C00008818 C00009075	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000134 C00000956 C00001071 C00001357 C00001431 C00001432 C00002935 C00009075	1 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000134 C00000956 C00001071 C00001357 C00001431 C00001432 C00002935 C00009075	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000134 C00000956 C00001071 C00001357 C00001431 C00001432 C00002935 C00009075	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000134 C00000956 C00001071 C00001357 C00001431 C00001432 C00002935 C00009075	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000956 C00001071 C00001357 C00001432 C00002935 C00003800 C00008818 C00009075	3 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000956 C00001071 C00001357 C00001518 C00003800 C00008818	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000956 C00001183 C00001357 C00001431 C00001432 C00001518	1 / 2
P10636	Microtubule-associated protein tau	Unclassified protein	C00000447 C00000956 C00001071 C00001357 C00001518 C00008818	4 / 3
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000956 C00001183 C00001357 C00001431 C00001432	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000956 C00001071 C00005178 C00005184 C00005224	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000447 C00000956 C00001071 C00001357 C00008818	2 / 3
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000956 C00001183 C00001357 C00001431 C00001432	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000956 C00001071 C00001357 C00001432 C00008818	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000956 C00001071 C00001357 C00003800 C00008818	2 / 2
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000956 C00001071 C00001357 C00001431 C00001432	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000956 C00001071 C00001201 C00001357 C00008818	0 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00000956 C00001071 C00001357 C00003800 C00008818	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000956 C00001071 C00001183 C00001357 C00008818	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000956 C00001183 C00001357 C00001431 C00001432	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001071 C00001183 C00001201 C00001357	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001071 C00001357 C00001432 C00008818	1 / 4
O43570	Carbonic anhydrase 12	Lyase	C00000956 C00001357 C00001431 C00001432	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001071 C00001357 C00001432 C00008818	0 / 1
P22748	Carbonic anhydrase 4	Lyase	C00000956 C00001357 C00001431 C00001432	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000956 C00001071 C00001357 C00008818	1 / 1
O75496	Geminin	Unclassified protein	C00001183 C00001201 C00001357 C00001518	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000956 C00001357 C00001431 C00001432	0 / 1
P11387	DNA topoisomerase 1	Isomerase	C00001071 C00005178 C00005184 C00005224	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000956 C00001357 C00001431 C00001432	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00000956 C00001357 C00001431 C00001432	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000956 C00001071 C00001357 C00001432	1 / 2
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000956 C00001357 C00001431 C00001432	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000956 C00001357 C00002935 C00009075	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000956 C00001071 C00001357 C00008818	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000134 C00000956 C00001183 C00001431	3 / 2
P07451	Carbonic anhydrase 3	Lyase	C00000956 C00001357 C00001431 C00001432	0 / 0
O00255	Menin	Unclassified protein	C00000956 C00001071 C00001357 C00001432	2 / 5
P39748	Flap endonuclease 1	Enzyme	C00000956 C00001071 C00001357	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000956 C00001357 C00008818	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000956 C00001071 C00001357	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001071 C00001431 C00001432	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000956 C00001071 C00003800	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000956 C00002935 C00009075	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000134 C00001183 C00001357	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001071 C00001183 C00001357	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000956 C00002935 C00009075	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000956 C00001071 C00008818	1 / 1
P40225	Thrombopoietin	Unclassified protein	C00001071 C00001431 C00001432	1 / 1
P06746	DNA polymerase beta	Enzyme	C00000956 C00001071 C00001357	0 / 0
Q05513	Protein kinase C zeta type	Iota	C00000956 C00002935 C00009075	0 / 0
Q04759	Protein kinase C theta type	Delta	C00000956 C00002935 C00009075	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00000956 C00001071 C00001357	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000956 C00001357 C00008818	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00000956 C00002935 C00009075	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00000956 C00002935 C00009075	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000956 C00001357 C00008818	0 / 0
P41743	Protein kinase C iota type	Iota	C00000956 C00002935 C00009075	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000956 C00001357 C00008818	0 / 0
P24723	Protein kinase C eta type	Eta	C00000956 C00002935 C00009075	1 / 0
P02768	Serum albumin	Secreted protein	C00000102 C00000956 C00008818	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000956 C00001357 C00003800	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00000956 C00001071 C00001357	1 / 2
P05771	Protein kinase C beta type	Alpha	C00000956 C00002935 C00009075	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00000956 C00002935 C00009075	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001071 C00001357 C00001432	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000956 C00001071 C00008818	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00001071 C00001518	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000956 C00001071	5 / 2
Q99700	Ataxin-2	Unclassified protein	C00001071 C00001357	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001183 C00001431	0 / 0
P56817	Beta-secretase 1	A1A	C00000956 C00008818	0 / 0
P00374	Dihydrofolate reductase	Oxidoreductase	C00000956 C00008818	1 / 1
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000956 C00001071	0 / 1
P03372	Estrogen receptor	NR3A1	C00000134 C00001357	1 / 1
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00000956 C00008818	2 / 3
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000956 C00001071	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00001071 C00001357	1 / 0
P23467	Receptor-type tyrosine-protein phosphatase beta	Receptor tyrosine-protein phosphatase	C00002935 C00009075	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00002935 C00009075	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00001357 C00003800	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00001071 C00001357	2 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00001357 C00003800	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00000956 C00001071	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001071 C00003800	2 / 2
Q16637	Survival motor neuron protein	Unclassified protein	C00000956 C00003800	4 / 1
P52209	6-phosphogluconate dehydrogenase, decarboxylating	Enzyme	C00000956 C00008818	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00001071 C00001357	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00001071 C00001357	0 / 0
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00000956 C00008818	0 / 7
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000956 C00001071	3 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00001357 C00003800	0 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000956 C00001071	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000956 C00001071	0 / 1
Q9H015	Solute carrier family 22 member 4	Unclassified protein	C00001431 C00001432	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001071 C00001357	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001071 C00001357	2 / 1
P33527	Multidrug resistance-associated protein 1	drugs	C00001071 C00001518	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00001071 C00001518	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001071 C00001431	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001071 C00001357	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001071 C00001357	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00001357	1 / 1
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000218	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00001431	0 / 0
P07998	Ribonuclease pancreatic	Enzyme	C00000956	0 / 0
P42858	Huntingtin	Unclassified protein	C00001357	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000956	2 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001357	0 / 0
O15439	Multidrug resistance-associated protein 4	Unclassified protein	C00001518	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001357	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00001357	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00001357	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00001357	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00001357	1 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00001071	1 / 1
Q92731	Estrogen receptor beta	NR3A2	C00001357	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00001357	0 / 0
P15121	Aldose reductase	Enzyme	C00001071	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00001357	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00001357	0 / 0
P10145	Interleukin-8	Secreted protein	C00000134	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00001357	1 / 0
P16581	E-selectin	Adhesion	C00001201	0 / 0
Q14790	Caspase-8	C14	C00001071	2 / 1
Q6QHF9	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	Enzyme	C00001431	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00001357	0 / 0
P08311	Cathepsin G	S1A	C00001357	0 / 0
P07711	Cathepsin L1	C1A	C00000956	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00001357	1 / 0
P09874	Poly [ADP-ribose] polymerase 1	Enzyme	C00003825	0 / 0
P03956	Interstitial collagenase	M10A	C00001357	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00001357	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00001357	1 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00001357	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00001357	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001071	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00001183	1 / 2
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00001357	0 / 0
Q15746	Myosin light chain kinase, smooth muscle	Mlck	C00001071	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00001071	0 / 0
P42575	Caspase-2	C14	C00001432	0 / 0
P00734	Prothrombin	S1A	C00000956	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00001357	0 / 1
P06213	Insulin receptor	TK tyrosine-protein kinase INSR subfamily	C00001071	5 / 4
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00001357	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00001357	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00001357	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00001357	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00001357	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001357	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00003800	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00001357	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00001357	1 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00001071	4 / 4
P21452	Substance-K receptor	Neurokinin receptor	C00001357	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00001198	0 / 0
P06276	Cholinesterase	Hydrolase	C00001071	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00001357	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00001357	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001357	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00003800	1 / 1
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00001357	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00001357	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00001357	2 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00001357	1 / 8
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00001357	1 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001071	1 / 0
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00001071	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00001357	2 / 1
Q9GZT9	Egl nine homolog 1	Enzyme	C00001183	1 / 1
Q12879	Glutamate receptor ionotropic, NMDA 2A	NS	C00001432	0 / 0
Q05586	Glutamate receptor ionotropic, NMDA 1	NS	C00001432	1 / 0
Q9Y2Q3	Glutathione S-transferase kappa 1	Enzyme	C00001518	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00001357	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00001357	0 / 0
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00000447	1 / 0
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000218	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00001357	0 / 0
P49327	Fatty acid synthase	Transferase	C00000956	0 / 0
O15217	Glutathione S-transferase A4	Enzyme	C00000447	0 / 0
Q9H2K2	Tankyrase-2	Enzyme	C00003825	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00001357	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00001071	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00001071	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00001357	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00001357	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001357	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001357	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00001357	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00001357	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00001357	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00001357	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00001357	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00001357	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000956	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00001071	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00001357	1 / 0
P55210	Caspase-7	C14	C00001357	0 / 0
P16109	P-selectin	Adhesion	C00001201	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00001357	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00001357	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00001357	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00001357	0 / 1
Q15046	Lysine--tRNA ligase	Enzyme	C00001071	2 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00000956	1 / 0
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000218	1 / 0
P05091	Aldehyde dehydrogenase, mitochondrial	Oxidoreductase	C00003800	1 / 1
P42574	Caspase-3	C14	C00001432	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000956	5 / 1
P10828	Thyroid hormone receptor beta	NR1A2	C00001357	3 / 1
Q8TD43	Transient receptor potential cation channel subfamily M member 4	Unclassified protein	C00001432	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00001518	11 / 10
P10275	Androgen receptor	NR3C4	C00000134	3 / 4
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00001357	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00001357	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00001357	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00003800	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00001357	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00001183	0 / 0
O95271	Tankyrase-1	Enzyme	C00003825	0 / 0
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001357	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00000956	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00001357	0 / 0
O14746	Telomerase reverse transcriptase	Enzyme	C00003825	5 / 5
P14780	Matrix metalloproteinase-9	M10A	C00001357	2 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00003800	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00001357	0 / 0
P29466	Caspase-1	C14	C00001357	0 / 0
P42336	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Enzyme	C00001071	9 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000956	1 / 1
P04062	Glucosylceramidase	Enzyme	C00001071	6 / 4
P46059	Solute carrier family 15 member 1	Dipeptide	C00001357	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00001357	0 / 0
P61073	C-X-C chemokine receptor type 4	CXC chemokine receptor	C00001432	1 / 1
Q16539	Mitogen-activated protein kinase 14	p38	C00001357	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000956	3 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00001357	0 / 0
P08246	Neutrophil elastase	S1A	C00001357	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001357	2 / 2
Q16798	NADP-dependent malic enzyme, mitochondrial	Enzyme	C00001183	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001071	2 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001198	0 / 0
P31941	DNA dC->dU-editing enzyme APOBEC-3A	Enzyme	C00001071	0 / 0
Q9NZQ8	Transient receptor potential cation channel subfamily M member 5	Unclassified protein	C00001432	0 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000218	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00001183	7 / 37
Q96QA9	Multidrug resistance associated protein	Unclassified protein	C00001518	0 / 0
Q05BR4	SLC16A10 protein	Unclassified protein	C00001357	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000956	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000956	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000956	3 / 0
Q9C0B1	Alpha-ketoglutarate-dependent dioxygenase FTO	Unclassified protein	C00001183	1 / 2
Q9HCT0	Fibroblast growth factor 22	Unclassified protein	C00001071	0 / 0

168 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000176 C00001071 C00001432 C00001518
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000176 C00001071 C00001431 C00001518
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001071 C00001518 C00007247
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001071 C00001518 C00007247
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00001071 C00001518
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000176 C00001518
153	ADRB1, ADRB1R, B1AR, BETA1AR, RHR	adrenoceptor beta 1	C00001431 C00001432
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00001431 C00001518
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001432 C00001518
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000176 C00001071
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001432 C00001518
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00001518 C00007247
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00001518 C00007247
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00001518 C00007247
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000176 C00001518
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000176 C00001518
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00001071 C00001518
891	CCNB1, CCNB	cyclin B1	C00000176 C00001071
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00001518 C00007247
581	BAX, BCL2L4	BCL2-associated X protein	C00001071 C00001518
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00001071 C00001518
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001518 C00007247
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001518 C00007247
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00001071 C00001518
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001071 C00001518
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00001071 C00001518
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001431 C00001432
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001071 C00001518
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001071 C00001518
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00001071 C00001518
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001071 C00001518
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00001071 C00001518
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00001071 C00001518
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00000176 C00001518
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001071 C00001518
5757	PTMA, TMSA	prothymosin, alpha	C00001518
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00001071
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00001071
54583	EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6	egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29)	C00001071
8505	PARG, PARG99	poly (ADP-ribose) glycohydrolase (EC:3.2.1.143)	C00001071
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00001071
8000	PSCA, PRO232	prostate stem cell antigen	C00001071
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001071
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00001071
23411	SIRT1, SIR2L1	sirtuin 1	C00001071
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00001071
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00001071
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00001071
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00001071
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00001071
7161	TP73, P73	tumor protein p73	C00001071
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00001518
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00001518
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00001518
368	ABCC6, ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	C00001518
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00001518
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00001518
8574	AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11)	C00001518
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001518
57412	AS3MT, CYT19	arsenic (+3 oxidation state) methyltransferase (EC:2.1.1.137)	C00001518
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00001518
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00001518
648	BMI1, FLVI2/BMI1, PCGF4, RNF51	BMI1 polycomb ring finger oncogene	C00001518
6364	CCL20, CKb4, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38	chemokine (C-C motif) ligand 20	C00001518
942	CD86, B7-2, B7.2, B70, CD28LG2, LAB72	CD86 molecule	C00001518
994	CDC25B	cell division cycle 25B (EC:3.1.3.48)	C00001518
995	CDC25C, CDC25, PPP1R60	cell division cycle 25C (EC:3.1.3.48)	C00001518
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00001518
1270	CNTF, HCNTF	ciliary neurotrophic factor	C00001518
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00001071
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00001518
847	CAT	catalase (EC:1.11.1.6)	C00001071
397	ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2	Rho GDP dissociation inhibitor (GDI) beta	C00001071
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00001518
1673	DEFB4A, BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1	defensin, beta 4A	C00001518
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00001518
2056	EPO, EP, MVCD2	erythropoietin	C00001518
14103			C00001518
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00001518
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00001518
2597	GAPDH, G3PD, GAPD	glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)	C00001518
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00000176
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00001518
2745	GLRX, GRX, GRX1	glutaredoxin (thioltransferase) (EC:1.8.4.1)	C00001518
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00001518
2937	GSS, GSHS	glutathione synthetase (EC:6.3.2.3)	C00001518
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00001518
2939	GSTA2, GST2, GSTA2-2, GTA2, GTH2	glutathione S-transferase alpha 2 (EC:2.5.1.18)	C00001518
2940	GSTA3, GSTA3-3, GTA3	glutathione S-transferase alpha 3 (EC:2.5.1.18)	C00001518
2941	GSTA4, GSTA4-4, GTA4	glutathione S-transferase alpha 4 (EC:2.5.1.18)	C00001518
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00001518
2946	GSTM2, GST4, GSTM, GSTM2-2, GTHMUS	glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18)	C00001518
2947	GSTM3, GST5, GSTB, GSTM3-3, GTM3	glutathione S-transferase mu 3 (brain) (EC:2.5.1.18)	C00001518
2948	GSTM4, GSTM4-4, GTM4	glutathione S-transferase mu 4 (EC:2.5.1.18)	C00001518
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00001518
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00001518
2954	GSTZ1, GSTZ1-1, MAAI, MAI	glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2)	C00001518
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00001518
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00001518
3458	IFNG, IFG, IFI	interferon, gamma	C00001518
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00001518
3596	IL13, IL-13, P600	interleukin 13	C00001518
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000176
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000176
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001518
3684	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6	integrin, alpha M (complement component 3 receptor 3 subunit)	C00001518
9817	KEAP1, INrf2, KLHL19	kelch-like ECH-associated protein 1	C00001518
9314	KLF4, EZF, GKLF	Kruppel-like factor 4 (gut)	C00001518
3932	LCK, LSK, YT16, p56lck, pp58lck	lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2)	C00001518
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00001518
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00001518
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00001518
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000176
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00001518
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00001518
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00001518
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00001518
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000176
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00001518
11315	PARK7, DJ-1, DJ1	parkinson protein 7	C00001518
5163	PDK1	pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2)	C00001518
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00001518
5446	PON3	paraoxonase 3 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00001518
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00001518
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00001518
10544	PROCR, CCCA, CCD41, EPCR	protein C receptor, endothelial	C00001518
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00001071
55312	RFK, RIFK	riboflavin kinase (EC:2.7.1.26)	C00001518
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00001518
6415	SEPW1, selW	selenoprotein W, 1	C00001518
9356	SLC22A6, HOAT1, OAT1, PAHT, ROAT1	solute carrier family 22 (organic anion transporter), member 6	C00001518
29986	SLC39A2, 6A1, ETI-1, ZIP-2, ZIP2	solute carrier family 39 (zinc transporter), member 2	C00001518
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00001518
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00001518
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001518
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00001518
6667	SP1	Sp1 transcription factor	C00001518
6670	SP3, SPR2	Sp3 transcription factor	C00001518
6671	SP4, HF1B, SPR-1	Sp4 transcription factor	C00001518
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00001518
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00001518
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00001518
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00001518
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00001518
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00001518
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00001518
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00001518
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00000176
898	CCNE1, CCNE	cyclin E1	C00000176
637	BID, FP497	BH3 interacting domain death agonist	C00000176
486	FXYD2, ATP1G1, HOMG2	FXYD domain containing ion transport regulator 2	C00001431
846	CASR, CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1	calcium-sensing receptor	C00001432
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00001432
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00007247
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00007247
1591	CYP24A1, CP24, CYP24, HCAI, P450-CC24	cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126)	C00007247
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00007247
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00007247
3992	FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12	fatty acid desaturase 1 (EC:1.14.19.-)	C00007247
3827	KNG1, BDK, BK, KNG	kininogen 1	C00007247
9971	NR1H4, BAR, FXR, HRR-1, HRR1, RIP14	nuclear receptor subfamily 1, group H, member 4	C00007247
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00007247
100136658			C00007247
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00007247
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00007247
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00007247
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00007247
26762	HAVCR1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1	hepatitis A virus cellular receptor 1	C00001198

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