PCIDB

KNApSAcK Metabolite C00000447

Metabolite

KNApSAcK Entry

id C00000447
Name 4-Hydroxy-2E-nonenal
CAS RN 75899-68-2
Standard InChI InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3/b7-5+
Standard InChI (Main Layer) InChI=1S/C9H16O2/c1-2-3-4-6-9(11)7-5-8-10/h5,7-9,11H,2-4,6H2,1H3

Cluster

Phytochemical cluster
KCF-S cluster No. 3536

Link

ChEMBL

By standard InChI CHEMBL454280
By standard InChI Main Layer CHEMBL454280

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Fabaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Vicia faba 3906 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
O15217 Glutathione S-transferase A4 Enzyme CHEMBL454280 CHEMBL1743225 (1)
0 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL454280 CHEMBL1794311 (1)
2 / 3
O75762 Transient receptor potential cation channel subfamily A member 1 Unclassified protein CHEMBL454280 CHEMBL966836 (1) CHEMBL966837 (1)
1 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL454280 CHEMBL1614250 (1)
4 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#615040 Episodic pain syndrome, familial, 1; feps1 O75762
#600274 Frontotemporal dementia; ftd P10636
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (6)

KEGG disease name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)