KCF-S cluster No. 2360 (5 metabolites)

Corresponding Phytochemical cluster No. 4

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
asterids	9

---

Cumulative family count

class name	count
Apocynaceae	9

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Indole alkaloids	5

---

metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Indole alkaloids	C09129	C00001705
Indole alkaloids	C09218	C00001743
Indole alkaloids	C09219	C00001744
Indole alkaloids	C07201	C00001781
Indole alkaloids	C07204	C00001783

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001705	Catharine
C00001743	Leurosidine	CHEMBL22969 CHEMBL159 CHEMBL150387 CHEMBL1315323 CHEMBL1437021 CHEMBL1518759 CHEMBL1625660 CHEMBL2311781		136 / 73 / 75
C00001744	Leurosine	CHEMBL508191 CHEMBL1183519 CHEMBL1187572	C002067
C00001781	Vinblastine	CHEMBL22969 CHEMBL159 CHEMBL150387 CHEMBL1315323 CHEMBL1437021 CHEMBL1518759 CHEMBL1625660 CHEMBL2311781	D014747	136 / 73 / 75	208 / 97
C00001783	Vincristine	CHEMBL90555 CHEMBL1363013 CHEMBL1396825 CHEMBL1740907 CHEMBL2134016	D014750	129 / 70 / 70	230 / 265

Human Protein / Gene in interactions

142 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001743 C00001781 C00001783	1 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001743 C00001781 C00001783	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00001743 C00001781 C00001783	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00001743 C00001781 C00001783	7 / 37
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00001743 C00001781 C00001783	1 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001743 C00001781 C00001783	1 / 1
Q9BVA1	Tubulin beta-2B chain	Structural	C00001743 C00001781 C00001783	1 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00001743 C00001781 C00001783	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001743 C00001781 C00001783	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00001743 C00001781 C00001783	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001743 C00001781 C00001783	2 / 2
P08246	Neutrophil elastase	S1A	C00001743 C00001781 C00001783	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00001743 C00001781 C00001783	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00001743 C00001781 C00001783	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00001743 C00001781 C00001783	0 / 0
P29466	Caspase-1	C14	C00001743 C00001781 C00001783	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00001743 C00001781 C00001783	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00001743 C00001781 C00001783	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00001743 C00001781 C00001783	2 / 2
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
Q13885	Tubulin beta-2A chain	Structural	C00001743 C00001781 C00001783	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00001743 C00001781 C00001783	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00001743 C00001781 C00001783	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00001743 C00001781 C00001783	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00001743 C00001781 C00001783	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00001743 C00001781 C00001783	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00001743 C00001781 C00001783	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	0 / 0
P68363	Tubulin alpha-1B chain	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
P08183	Multidrug resistance protein 1	drug	C00001743 C00001781 C00001783	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00001743 C00001781 C00001783	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00001743 C00001781 C00001783	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00001743 C00001781 C00001783	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001743 C00001781 C00001783	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00001743 C00001781 C00001783	1 / 8
Q13509	Tubulin beta-3 chain	Structural	C00001743 C00001781 C00001783	2 / 1
P14416	D(2) dopamine receptor	Dopamine receptor	C00001743 C00001781 C00001783	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001743 C00001781 C00001783	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00001743 C00001781 C00001783	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00001743 C00001781 C00001783	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00001743 C00001781 C00001783	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00001743 C00001781 C00001783	0 / 0
P68371	Tubulin beta-4B chain	Structural	C00001743 C00001781 C00001783	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00001743 C00001781 C00001783	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00001743 C00001781 C00001783	1 / 1
P07437	Tubulin beta chain	Structural	C00001743 C00001781 C00001783	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001743 C00001781 C00001783	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00001743 C00001781 C00001783	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00001743 C00001781 C00001783	1 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001743 C00001781 C00001783	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001743 C00001781 C00001783	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00001743 C00001781 C00001783	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001743 C00001781 C00001783	2 / 0
O75496	Geminin	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	C00001743 C00001781 C00001783	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001743 C00001781 C00001783	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00001743 C00001781 C00001783	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00001743 C00001781 C00001783	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00001743 C00001781 C00001783	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00001743 C00001781 C00001783	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00001743 C00001781 C00001783	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00001743 C00001781 C00001783	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00001743 C00001781 C00001783	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00001743 C00001781 C00001783	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00001743 C00001781 C00001783	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00001743 C00001781 C00001783	0 / 0
P08311	Cathepsin G	S1A	C00001743 C00001781 C00001783	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00001743 C00001781 C00001783	1 / 0
P03956	Interstitial collagenase	M10A	C00001743 C00001781 C00001783	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00001743 C00001781 C00001783	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00001743 C00001781 C00001783	1 / 0
P04350	Tubulin beta-4A chain	Structural	C00001743 C00001781 C00001783	2 / 0
P04150	Glucocorticoid receptor	NR3C1	C00001743 C00001781 C00001783	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00001743 C00001781 C00001783	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00001743 C00001781 C00001783	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00001743 C00001781 C00001783	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001743 C00001781 C00001783	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00001743 C00001781 C00001783	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00001743 C00001781 C00001783	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00001743 C00001781 C00001783	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00001743 C00001781 C00001783	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00001743 C00001781 C00001783	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001743 C00001781 C00001783	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00001743 C00001781 C00001783	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00001743 C00001781 C00001783	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00001743 C00001781 C00001783	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001743 C00001781 C00001783	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00001743 C00001781 C00001783	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	C00001743 C00001781 C00001783	1 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00001743 C00001781 C00001783	0 / 0
P03372	Estrogen receptor	NR3A1	C00001743 C00001781 C00001783	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00001743 C00001781 C00001783	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001743 C00001781 C00001783	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001743 C00001781 C00001783	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001743 C00001781 C00001783	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00001743 C00001781 C00001783	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00001743 C00001781 C00001783	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00001743 C00001781 C00001783	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00001743 C00001781 C00001783	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001743 C00001781 C00001783	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001743 C00001781 C00001783	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001743 C00001781 C00001783	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00001743 C00001781 C00001783	0 / 0
P68366	Tubulin alpha-4A chain	Structural	C00001743 C00001781 C00001783	0 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00001743 C00001781 C00001783	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001743 C00001781 C00001783	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00001743 C00001781 C00001783	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00001743 C00001781 C00001783	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00001743 C00001781 C00001783	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00001743 C00001781 C00001783	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00001743 C00001781 C00001783	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00001743 C00001781 C00001783	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001743 C00001781 C00001783	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00001743 C00001781 C00001783	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001743 C00001781	0 / 0
O00255	Menin	Unclassified protein	C00001743 C00001781	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001743 C00001781	1 / 2
O95342	Bile salt export pump	drug	C00001743 C00001781	2 / 1
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001743 C00001781	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001743 C00001781	4 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00001743 C00001781	0 / 0
P21439	Multidrug resistance protein 3	Enzyme	C00001743 C00001781	3 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001743 C00001781	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00001743 C00001781	2 / 3
P16473	Thyrotropin receptor	Glycohormone receptor	C00001743 C00001781	3 / 2
P04183	Thymidine kinase, cytosolic	Enzyme	C00001743 C00001781	0 / 1
P51151	Ras-related protein Rab-9A	Unclassified protein	C00001743 C00001781	0 / 0
P11926	Ornithine decarboxylase	Lyase	C00001783	0 / 0
P42858	Huntingtin	Unclassified protein	C00001783	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00001783	11 / 10
Q5T3U5	Multidrug resistance-associated protein 7	Unclassified protein	C00001783	0 / 0
Q96QA9	Multidrug resistance associated protein	Unclassified protein	C00001783	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001783	2 / 0

420 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001781 C00001783
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00001781 C00001783
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00001781 C00001783
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001781 C00001783
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001781 C00001783
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00001781 C00001783
54870	QRICH1	glutamine-rich 1	C00001781 C00001783
9055	PRC1, ASE1	protein regulator of cytokinesis 1	C00001781 C00001783
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00001781 C00001783
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001781 C00001783
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001781 C00001783
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001781 C00001783
10643	IGF2BP3, CT98, IMP-3, IMP3, KOC1, VICKZ3	insulin-like growth factor 2 mRNA binding protein 3	C00001781 C00001783
3161	HMMR, CD168, IHABP, RHAMM	hyaluronan-mediated motility receptor (RHAMM)	C00001781 C00001783
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00001781 C00001783
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00001781 C00001783
891	CCNB1, CCNB	cyclin B1	C00001781 C00001783
847	CAT	catalase (EC:1.11.1.6)	C00001781 C00001783
159162	RBMY2FP	RNA binding motif protein, Y-linked, family 2, member F pseudogene	C00001783
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001781
699	BUB1, BUB1A, BUB1L, hBUB1	BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1)	C00001781
79444	BIRC7, KIAP, LIVIN, ML-IAP, MLIAP, RNF50	baculoviral IAP repeat containing 7	C00001781
9133	CCNB2, HsT17299	cyclin B2	C00001781
959	CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L	CD40 ligand	C00001781
34411			C00001781
55143	CDCA8, BOR, BOREALIN, DasraB, MESRGP	cell division cycle associated 8	C00001781
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00001781
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00001781
1058	CENPA, CENP-A, CenH3	centromere protein A	C00001781
26586	CKAP2, LB1, TMAP, se20-10	cytoskeleton associated protein 2	C00001781
10063	COX17	COX17 cytochrome c oxidase copper chaperone	C00001781
9377	COX5A, COX, COX-VA, VA	cytochrome c oxidase subunit Va (EC:1.9.3.1)	C00001781
1340	COX6B1, COX6B, COXG, COXVIb1	cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) (EC:1.9.3.1)	C00001781
8804	CREG1, CREG	cellular repressor of E1A-stimulated genes 1	C00001781
9419	CRIPT	cysteine-rich PDZ-binding protein	C00001781
1490	CTGF, CCN2, HCS24, IGFBP8, NOV2	connective tissue growth factor	C00001781
6374	CXCL5, ENA-78, SCYB5	chemokine (C-X-C motif) ligand 5	C00001781
100528464			C00001781
28960	DCPS, DCS1, HINT-5, HINT5, HSL1	decapping enzyme, scavenger (EC:3.6.1.59)	C00001781
9416	DDX23, PRPF28, SNRNP100, U5-100K, U5-100KD, prp28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 (EC:3.6.4.13)	C00001781
51071	DERA, DEOC	deoxyribose-phosphate aldolase (putative) (EC:4.1.2.4)	C00001781
1677	DFFB, CAD, CPAN, DFF-40, DFF2, DFF40	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	C00001781
22943	DKK1, DKK-1, SK	dickkopf WNT signaling pathway inhibitor 1	C00001781
27122	DKK3, REIC, RIG	dickkopf WNT signaling pathway inhibitor 3	C00001781
29980	DONSON, B17, C21orf60	downstream neighbor of SON	C00001781
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00001781
84455	EFCAB7, RP4-534K7.1	EF-hand calcium binding domain 7	C00001781
2013	EMP2, XMP	epithelial membrane protein 2	C00001781
4072	EPCAM, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1	epithelial cell adhesion molecule	C00001781
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00001781
2069	EREG, ER	epiregulin	C00001781
2109	ETFB, MADD	electron-transfer-flavoprotein, beta polypeptide	C00001781
5393	EXOSC9, PM/Scl-75, PMSCL1, RRP45, Rrp45p, p5, p6	exosome component 9 (EC:3.1.13.-)	C00001781
10447	FAM3C, ILEI	family with sequence similarity 3, member C	C00001781
388650	FAM69A	family with sequence similarity 69, member A	C00001781
55120	FANCL, FAAP43, PHF9, POG	Fanconi anemia, complementation group L	C00001781
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00001781
2237	FEN1, FEN-1, MF1, RAD2	flap structure-specific endonuclease 1	C00001781
2280	FKBP1A, FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE	FK506 binding protein 1A, 12kDa (EC:5.2.1.8)	C00001781
2313	FLI1, EWSR2, SIC-1	Fli-1 proto-oncogene, ETS transcription factor	C00001781
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00001781
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00001781
50486	G0S2, RP1-28O10.2	G0/G1switch 2	C00001781
79017	GGCT, C7orf24, CRF21, GCTG, GGC	gamma-glutamylcyclotransferase (EC:2.3.2.4)	C00001781
2677	GGCX, VKCFD1	gamma-glutamyl carboxylase (EC:4.1.1.90)	C00001781
51053	GMNN, Gem	geminin, DNA replication inhibitor	C00001781
79158	GNPTAB, GNPTA, ICD	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (EC:2.7.8.17)	C00001781
11245	GPR176, HB-954	G protein-coupled receptor 176	C00001781
29899	GPSM2, CMCS, DFNB82, LGN, PINS	G-protein signaling modulator 2	C00001781
2969	GTF2I, BAP135, BTKAP1, DIWS, GTFII-I, IB291, SPIN, TFII-I, WBS, WBSCR6	general transcription factor IIi	C00001781
2971	GTF3A, AP2, TFIIIA	general transcription factor IIIA	C00001781
51512	GTSE1, B99	G-2 and S-phase expressed 1	C00001781
2990	GUSB, BG, MPS7	glucuronidase, beta (EC:3.2.1.31)	C00001781
3033	HADH, HAD, HADH1, HADHSC, HCDH, HHF4, MSCHAD, SCHAD	hydroxyacyl-CoA dehydrogenase (EC:1.1.1.35)	C00001781
3059	HCLS1, CTTNL, HS1	hematopoietic cell-specific Lyn substrate 1	C00001781
3006	HIST1H1C, H1.2, H1C, H1F2, H1s-1	histone cluster 1, H1c	C00001781
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00001781
3148	HMGB2, HMG2	high mobility group box 2	C00001781
9324	HMGN3, PNAS-25, TRIP7	high mobility group nucleosomal binding domain 3	C00001781
558	AXL, JTK11, UFO	AXL receptor tyrosine kinase (EC:2.7.10.1)	C00001781
9456	HOMER1, HOMER, HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1	homer homolog 1 (Drosophila)	C00001781
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00001781
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00001781
3418	IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH	isocitrate dehydrogenase 2 (NADP+), mitochondrial (EC:1.1.1.42)	C00001781
9212	AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5, aurkb-sv1, aurkb-sv2	aurora kinase B (EC:2.7.11.1)	C00001781
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00001781
3598	IL13RA2, CD213A2, CT19, IL-13R, IL13BP	interleukin 13 receptor, alpha 2	C00001781
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00001781
9551	ATP5J2, ATP5JL	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 (EC:3.6.1.14)	C00001781
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001781
3624	INHBA, EDF, FRP	inhibin, beta A	C00001781
3683	ITGAL, CD11A, LFA-1, LFA1A	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	C00001781
9270	ITGB1BP1, ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B	integrin beta 1 binding protein 1	C00001781
521	ATP5I, ATP5K	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E (EC:3.6.1.14)	C00001781
23189	KANK1, ANKRD15, CPSQ2, KANK	KN motif and ankyrin repeat domains 1	C00001781
23254	KAZN, KAZ	kazrin, periplakin interacting protein	C00001781
57698		KIAA1598	C00001781
3832	KIF11, EG5, HKSP, KNSL1, MCLMR, TRIP5	kinesin family member 11	C00001781
56992	KIF15, HKLP2, KNSL7, NY-BR-62	kinesin family member 15	C00001781
23095	KIF1B, CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1	kinesin family member 1B	C00001781
10112	KIF20A, MKLP2, RAB6KIFL	kinesin family member 20A	C00001781
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00001781
24137	KIF4A, KIF4, KIF4G1	kinesin family member 4A	C00001781
3838	KPNA2, IPOA1, QIP2, RCH1, SRP1alpha	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	C00001781
4001	LMNB1, ADLD, LMN, LMN2, LMNB	lamin B1	C00001781
1902	LPAR1, EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1	lysophosphatidic acid receptor 1	C00001781
55227	LRRC1, LANO, dJ523E19.1	leucine rich repeat containing 1	C00001781
51690	LSM7, YNL147W	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	C00001781
4053	LTBP2, C14orf141, GLC3D, LTBP3, MSPKA, MSTP031, WMS3	latent transforming growth factor beta binding protein 2	C00001781
4085	MAD2L1, HSMAD2, MAD2	MAD2 mitotic arrest deficient-like 1 (yeast)	C00001781
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00001781
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00001781
8550	MAPKAPK5, MAPKAP-K5, MK-5, MK5, PRAK	mitogen-activated protein kinase-activated protein kinase 5 (EC:2.7.11.1)	C00001781
9833	MELK, HPK38	maternal embryonic leucine zipper kinase (EC:2.7.11.1 2.7.10.2)	C00001781
4311	MME, CALLA, CD10, NEP, SFE	membrane metallo-endopeptidase (EC:3.4.24.11)	C00001781
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00001781
5891	MOK, RAGE, RAGE-1, RAGE1	MOK protein kinase (EC:2.7.11.22)	C00001781
78988	MRP63, bMRP63	mitochondrial ribosomal protein 63	C00001781
51765	MST4, MASK	serine/threonine protein kinase MST4 (EC:2.7.11.1)	C00001781
27350	APOBEC3C, A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C	C00001781
26292	MYCBP, AMY-1	MYC binding protein	C00001781
64151	NCAPG, CAPG, CHCG, NY-MEL-3	non-SMC condensin I complex, subunit G	C00001781
23397	NCAPH, BRRN1, CAP-H	non-SMC condensin I complex, subunit H	C00001781
10403	NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80	NDC80 kinetochore complex component	C00001781
4694	NDUFA1, CI-MWFE, MWFE, ZNF183	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (EC:1.6.99.3)	C00001781
51079	NDUFA13, B16.6, CDA016, GRIM-19, GRIM19	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	C00001781
4696	NDUFA3, B9, CI-B9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	C00001781
4701	NDUFA7, B14.5a	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa	C00001781
4708	NDUFB2, AGGG, CI-AGGG	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (EC:1.6.5.3 1.6.99.3)	C00001781
4717	NDUFC1, KFYI	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	C00001781
4718	NDUFC2, B14.5b, CI-B14.5b, HLC-1, NADHDH2	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa	C00001781
4726	NDUFS6, CI-13kA, CI-13kD-A, CI13KDA	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3)	C00001781
4729	NDUFV2, CI-24k	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (EC:1.6.5.3 1.6.99.3)	C00001781
4776	NFATC4, NF-ATc4, NFAT3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	C00001781
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00001781
316	AOX1, AO, AOH1	aldehyde oxidase 1 (EC:1.2.3.1)	C00001781
8439	NSMAF, FAN	neutral sphingomyelinase (N-SMase) activation associated factor	C00001781
55270	NUDT15, MTH2, RP11-90M2.1	nudix (nucleoside diphosphate linked moiety X)-type motif 15 (EC:3.6.1.55)	C00001781
11163	NUDT4, DIPP2, DIPP2alpha, DIPP2beta	nudix (nucleoside diphosphate linked moiety X)-type motif 4 (EC:3.6.1.52)	C00001781
51203	NUSAP1, ANKT, BM037, LNP, NUSAP, PRO0310p1, Q0310, SAPL	nucleolar and spindle associated protein 1	C00001781
4946	OAZ1, AZI, OAZ	ornithine decarboxylase antizyme 1	C00001781
11339	OIP5, 5730547N13Rik, CT86, LINT-25, MIS18B, MIS18beta, hMIS18beta	Opa interacting protein 5	C00001781
401903			C00001781
126370	OR1I1, OR19-20, OR1I1P, OR1I1Q	olfactory receptor, family 1, subfamily I, member 1	C00001781
23594	ORC6, ORC6L	origin recognition complex, subunit 6	C00001781
114884	OSBPL10, ORP10, OSBP9	oxysterol binding protein-like 10	C00001781
3355109			C00001781
5162	PDHB, PDHBD, PDHE1-B, PHE1B	pyruvate dehydrogenase (lipoamide) beta (EC:1.2.4.1)	C00001781
53918	PELO, PRO1770	pelota homolog (Drosophila)	C00001781
10857	PGRMC1, HPR6.6, MPR	progesterone receptor membrane component 1	C00001781
8544	PIR	pirin (iron-binding nuclear protein) (EC:1.13.11.24)	C00001781
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00001781
120	ADD3, ADDL	adducin 3 (gamma)	C00001781
5689	PSMB1, HC5, PMSB1, PSC5	proteasome (prosome, macropain) subunit, beta type, 1 (EC:3.4.25.1)	C00001781
23198	PSME4, PA200	proteasome (prosome, macropain) activator subunit 4	C00001781
10728	PTGES3, P23, TEBP, cPGES	prostaglandin E synthase 3 (cytosolic) (EC:5.3.99.3)	C00001781
9232	PTTG1, EAP1, HPTTG, PTTG, TUTR1	pituitary tumor-transforming 1	C00001781
5806	PTX3, TNFAIP5, TSG-14	pentraxin 3, long	C00001781
52	ACP1, HAAP	acid phosphatase 1, soluble (EC:3.1.3.2 3.1.3.48)	C00001781
80223	RAB11FIP1, NOEL1A, RCP, rab11-FIP1	RAB11 family interacting protein 1 (class I)	C00001781
29127	RACGAP1, CYK4, HsCYK-4, ID-GAP, MgcRacGAP	Rac GTPase activating protein 1	C00001781
5902	RANBP1, HTF9A	RAN binding protein 1	C00001781
5980	REV3L, POLZ, REV3	REV3-like, polymerase (DNA directed), zeta, catalytic subunit (EC:2.7.7.7)	C00001781
5985	RFC5, RFC36	replication factor C (activator 1) 5, 36.5kDa	C00001781
6119	RPA3, REPA3	replication protein A3, 14kDa	C00001781
393715			C00001781
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00001781
55856	ACOT13, PNAS-27, THEM2	acyl-CoA thioesterase 13	C00001781
39	ACAT2	acetyl-CoA acetyltransferase 2 (EC:2.3.1.9)	C00001781
94081	SFXN1	sideroflexin 1	C00001781
6502	SKP2, FBL1, FBXL1, FLB1, p45	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase	C00001781
6581	SLC22A3, EMT, EMTH, OCT3	solute carrier family 22 (organic cation transporter), member 3	C00001781
79622	SNRNP25, C16orf33	small nuclear ribonucleoprotein 25kDa (U11/U12)	C00001781
29887	SNX10, OPTB8	sorting nexin 10	C00001781
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00001781
6272	SORT1, Gp95, LDLCQ6, NT3	sortilin 1	C00001781
6715	SRD5A1, S5AR_1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (EC:1.3.1.22)	C00001781
5552	SRGN, PPG, PRG, PRG1	serglycin	C00001781
8614	STC2, STC-2, STCRP	stanniocalcin 2	C00001781
6801	STRN, SG2NA	striatin, calmodulin binding protein	C00001781
8803	SUCLA2, A-BETA, MTDPS5, SCS-betaA	succinate-CoA ligase, ADP-forming, beta subunit (EC:6.2.1.5)	C00001781
8802	SUCLG1, GALPHA, MTDPS9, SUCLA1	succinate-CoA ligase, alpha subunit (EC:6.2.1.4 6.2.1.5)	C00001781
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00001781
85360	SYDE1, 7h3	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	C00001781
9882	TBC1D4, AS160	TBC1 domain family, member 4	C00001781
6996	TDG, hTDG	thymine-DNA glycosylase (EC:3.2.2.29)	C00001781
7980	TFPI2, PP5, REF1, TFPI-2	tissue factor pathway inhibitor 2	C00001781
80194	TMEM134	transmembrane protein 134	C00001781
28978	TMEM14A, C6orf73	transmembrane protein 14A	C00001781
80008	TMEM156	transmembrane protein 156	C00001781
27346	TMEM97, MAC30	transmembrane protein 97	C00001781
7112	TMPO, CMD1T, LAP2, LEMD4, PRO0868, TP	thymopoietin	C00001781
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00001781
3983	ABLIM1, ABLIM, LIMAB1, LIMATIN, abLIM-1	actin binding LIM protein 1	C00001781
7164	TPD52L1, D53, hD53	tumor protein D52-like 1	C00001781
23321	TRIM2, CMT2R, RNF86	tripartite motif containing 2	C00001781
57570	TRMT5, KIAA1393, TRM5	tRNA methyltransferase 5 (EC:2.1.1.228)	C00001781
27075	TSPAN13, NET-6, NET6, TM4SF13	tetraspanin 13	C00001781
8458	TTF2, HuF2	transcription termination factor, RNA polymerase II	C00001781
7272	TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT	TTK protein kinase (EC:2.7.12.1)	C00001781
659925			C00001781
7424	VEGFC, Flt4-L, VRP	vascular endothelial growth factor C	C00001781
80349	WDR61, REC14, SKI8	WD repeat domain 61	C00001781
55884	WSB2, SBA2	WD repeat and SOCS box containing 2	C00001781
10971	YWHAQ, 14-3-3, 1C5, HS1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	C00001781
79844	ZDHHC11, ZNF399	zinc finger, DHHC-type containing 11 (EC:2.3.1.225)	C00001781
678	ZFP36L2, BRF2, ERF-2, ERF2, RNF162C, TIS11D	ZFP36 ring finger protein-like 2	C00001781
11130	ZWINT, HZwint-1, KNTC2AP, ZWINT1	ZW10 interacting kinetochore protein	C00001781
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00001783
26154	ABCA12, ARCI4A, ARCI4B, ICR2B, LI2	ATP-binding cassette, sub-family A (ABC1), member 12	C00001783
24	ABCA4, ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1	ATP-binding cassette, sub-family A (ABC1), member 4	C00001783
23461	ABCA5, ABC13, EST90625	ATP-binding cassette, sub-family A (ABC1), member 5	C00001783
10351	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	C00001783
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00001783
5244	ABCB4, ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3	ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44)	C00001783
10058	ABCB6, ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat	ATP-binding cassette, sub-family B (MDR/TAP), member 6	C00001783
89845	ABCC10, EST182763, MRP7, SIMRP7	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	C00001783
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00001783
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00001783
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00001783
368	ABCC6, ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	C00001783
5825	ABCD3, ABC43, PMP70, PXMP1, ZWS2	ATP-binding cassette, sub-family D (ALD), member 3	C00001783
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001783
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00001783
64137	ABCG4, WHITE2	ATP-binding cassette, sub-family G (WHITE), member 4	C00001783
81569	ACTL8, CT57	actin-like 8	C00001783
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001783
57379	AICDA, AID, ARP2, CDA2, HIGM2	activation-induced cytidine deaminase (EC:3.5.4.38)	C00001783
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001783
216	ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH1	aldehyde dehydrogenase 1 family, member A1 (EC:1.2.1.36)	C00001783
410	ARSA, MLD	arylsulfatase A (EC:3.1.6.8)	C00001783
259266	ASPM, ASP, Calmbp1, MCPH5	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	C00001783
538	ATP7A, DSMAX, MK, MNK, SMAX3	ATPase, Cu++ transporting, alpha polypeptide (EC:3.6.3.54)	C00001783
540	ATP7B, PWD, WC1, WD, WND	ATPase, Cu++ transporting, beta polypeptide (EC:3.6.3.54)	C00001783
6790	AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7	aurora kinase A (EC:2.7.11.1)	C00001783
551	AVP, ADH, ARVP, AVP-NPII, AVRP, VP	arginine vasopressin	C00001783
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00001783
581	BAX, BCL2L4	BCL2-associated X protein	C00001783
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00001783
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00001783
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00001783
675	BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2	breast cancer 2, early onset	C00001783
100170841	C17orf96	chromosome 17 open reading frame 96	C00001783
8618	CADPS, CADPS1, CAPS, CAPS1	Ca++-dependent secretion activator	C00001783
84254	CAMKK1, CAMKKA	calcium/calmodulin-dependent protein kinase kinase 1, alpha (EC:2.7.11.17)	C00001783
57082	CASC5, AF15Q14, CT29, D40, KNL1, PPP1R55, Spc7, hKNL-1, hSpc105	cancer susceptibility candidate 5	C00001783
839	CASP6, MCH2	caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59)	C00001783
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00001783
890	CCNA2, CCN1, CCNA	cyclin A2	C00001783
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00001783
157313	CDCA2, Repo-Man	cell division cycle associated 2	C00001783
1020	CDK5, PSSALRE	cyclin-dependent kinase 5 (EC:2.7.11.22)	C00001783
1022	CDK7, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15	cyclin-dependent kinase 7 (EC:2.7.11.23 2.7.11.22)	C00001783
1029	CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16	cyclin-dependent kinase inhibitor 2A	C00001783
1051	CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5	CCAAT/enhancer binding protein (C/EBP), beta	C00001783
11190	CEP250, C-NAP1, CEP2, CNAP1	centrosomal protein 250kDa	C00001783
23563	CHST5, I-GlcNAc-6-ST, I-GlcNAc6ST, glcNAc6ST-3, gn6st-3, hIGn6ST	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	C00001783
57019	CIAPIN1, 2810413N20Rik, Anamorsin, DRE2, PRO0915	cytokine induced apoptosis inhibitor 1	C00001783
23242	COBL	cordon-bleu WH2 repeat protein	C00001783
1299	COL9A3, DJ885L7.4.1, EDM3, IDD, MED	collagen, type IX, alpha 3	C00001783
1396	CRIP1, CRHP, CRIP, CRP-1, CRP1	cysteine-rich protein 1 (intestinal)	C00001783
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00001783
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001783
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00001783
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001783
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00001783
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00001783
1582	CYP8B1, CP8B, CYP12	cytochrome P450, family 8, subfamily B, polypeptide 1 (EC:1.14.13.95)	C00001783
1617	DAZ1, DAZ, SPGY	deleted in azoospermia 1	C00001783
57054	DAZ3, pDP1679	deleted in azoospermia 3	C00001783
57135	DAZ4, pDP1680, pDP1681	deleted in azoospermia 4	C00001783
11056	DDX52, HUSSY19, ROK1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 (EC:3.6.4.13)	C00001783
9046	DOK2, p56DOK, p56dok-2	docking protein 2, 56kDa	C00001783
1806	DPYD, DHP, DHPDHASE, DPD	dihydropyrimidine dehydrogenase (EC:1.3.1.2)	C00001783
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00001783
79071	ELOVL6, FACE, FAE, LCE	ELOVL fatty acid elongase 6 (EC:2.3.1.199)	C00001783
2052	EPHX1, EPHX, EPOX, HYL1, MEH	epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9)	C00001783
2068	ERCC2, COFS2, EM9, TTD, XPD	excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12)	C00001783
9156	EXO1, HEX1, hExoI	exonuclease 1	C00001783
2147	F2, PT, RPRGL2, THPH1	coagulation factor II (thrombin) (EC:3.4.21.5)	C00001783
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00001783
84668	FAM126A, DRCTNNB1A, HCC, HLD5, HYCC1	family with sequence similarity 126, member A	C00001783
55215	FANCI, KIAA1794	Fanconi anemia, complementation group I	C00001783
9103	FCGR2C, CD32, CD32C, CDW32, FCG2, FCRIIC, IGFR2	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	C00001783
2264	FGFR4, CD334, JTK2, TKF	fibroblast growth factor receptor 4 (EC:2.7.10.1)	C00001783
9896	FIG4, ALS11, CMT4J, KIAA0274, SAC3, YVS, dJ249I4.1	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	C00001783
2528	FUT6, FCT3A, FT1A, Fuc-TVI, FucT-VI	fucosyltransferase 6 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65)	C00001783
26748	GAGE12I, AL4, CT4.7, GAGE-7B, GAGE7B	G antigen 12I	C00001783
2574	GAGE2C, CT4.2, GAGE-2, GAGE-2C, GAGE2	G antigen 2C	C00001783
2575			C00001783
2576	GAGE4, CT4.4	G antigen 4	C00001783
2578	GAGE6, CT4.6	G antigen 6	C00001783
2579	GAGE7, AL4, CT4.7, GAGE-7	G antigen 7	C00001783
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00001783
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00001783
51608	GET4, C7orf20, CEE, TRC35	golgi to ER traffic protein 4 homolog (S. cerevisiae)	C00001783
2690	GHR, GHBP	growth hormone receptor	C00001783
2735	GLI1, GLI	GLI family zinc finger 1	C00001783
2838	GPR15, BOB	G protein-coupled receptor 15	C00001783
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001783
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00001783
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00001783
2954	GSTZ1, GSTZ1-1, MAAI, MAI	glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2)	C00001783
2965	GTF2H1, BTF2, P62, TFB1, TFIIH	general transcription factor IIH, polypeptide 1, 62kDa	C00001783
3044	HBBP1	hemoglobin, beta pseudogene 1	C00001783
113510	HELQ, HEL308	helicase, POLQ-like (EC:3.6.4.12)	C00001783
9709	HERPUD1, HERP, Mif1, SUP	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	C00001783
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00001783
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00001783
3399	ID3, HEIR-1, bHLHb25	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	C00001783
10561	IFI44, MTAP44, TLDC5, p44	interferon-induced protein 44	C00001783
3439	IFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@	interferon, alpha 1	C00001783
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00001783
3500			C00001783
3508	IGHMBP2, CATF1, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7	immunoglobulin mu binding protein 2 (EC:3.6.4.13 3.6.4.12)	C00001783
9118	INA, NEF5, NF-66, TXBP-1	internexin neuronal intermediate filament protein, alpha	C00001783
9452	ITM2A, BRICD2A, E25A	integral membrane protein 2A	C00001783
3741	KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1	potassium voltage-gated channel, shaker-related subfamily, member 5	C00001783
9757	KMT2B, HRX2, MLL1B, MLL2, MLL4, TRX2, WBP7	lysine (K)-specific methyltransferase 2B (EC:2.1.1.43)	C00001783
3904	LAIR2, CD306	leukocyte-associated immunoglobulin-like receptor 2	C00001783
10859	LILRB1, CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7, MIR7	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	C00001783
11006	LILRB4, CD85K, ILT-3, ILT3, LIR-5, LIR5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	C00001783
4041	LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2	low density lipoprotein receptor-related protein 5	C00001783
4049	LTA, LT, TNFB, TNFSF1	lymphotoxin alpha	C00001783
4101	MAGEA2, CT1.2, MAGE2, MAGEA2A	melanoma antigen family A, 2	C00001783
266740	MAGEA2B, MAGE2, MAGEA2	melanoma antigen family A, 2B	C00001783
23005	MAPKBP1, JNKBP-1	mitogen-activated protein kinase binding protein 1	C00001783
22919	MAPRE1, EB1	microtubule-associated protein, RP/EB family, member 1	C00001783
22924	MAPRE3, EB3, EBF3, EBF3-S, RP3	microtubule-associated protein, RP/EB family, member 3	C00001783
4153	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD	mannose-binding lectin (protein C) 2, soluble	C00001783
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00001783
54842	MFSD6, MMR2, hMMR2	major facilitator superfamily domain containing 6	C00001783
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00001783
440823	MIAT, C22orf35, GOMAFU, LINC00066, NCRNA00066, RNCR2	myocardial infarction associated transcript (non-protein coding)	C00001783
574456	MIR497, MIRN497, hsa-mir-497	microRNA 497	C00001783
4288	MKI67, KIA, MIB-1	marker of proliferation Ki-67	C00001783
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00001783
4595	MUTYH, CYP2C, MYH	mutY homolog (EC:3.2.2.-)	C00001783
4613	MYCN, MODED, MYCNOT, N-myc, NMYC, ODED, bHLHe37	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	C00001783
53904	MYO3A, DFNB30	myosin IIIA (EC:2.7.11.1)	C00001783
9	NAT1, AAC1, MNAT, NAT-1, NATI	N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5)	C00001783
4773	NFATC2, NFAT1, NFATP	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	C00001783
10577	NPC2, EDDM1, HE1	Niemann-Pick disease, type C2	C00001783
8829	NRP1, BDCA4, CD304, NP1, NRP, VEGF165R	neuropilin 1	C00001783
114880	OSBPL6, ORP6	oxysterol binding protein-like 6	C00001783
55644	OSGEP, GCPL1, KAE1, OSGEP1, PRSMG1	O-sialoglycoprotein endopeptidase (EC:3.4.24.57)	C00001783
8712	PAGE1, AL5, CT16.3, GAGE-9, GAGEB1, PAGE-1	P antigen family, member 1 (prostate associated)	C00001783
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001783
23178	PASK, PASKIN, STK37	PAS domain containing serine/threonine kinase (EC:2.7.11.1)	C00001783
301164			C00001783
25894	PLEKHG4, ARHGEF44, PRTPHN1, SCA4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	C00001783
84898	PLXDC2, TEM7R	plexin domain containing 2	C00001783
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00001783
5423	POLB	polymerase (DNA directed), beta (EC:2.7.7.7)	C00001783
5428	POLG, MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE	polymerase (DNA directed), gamma (EC:2.7.7.7)	C00001783
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00001783
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00001783
84152	PPP1R1B, DARPP-32, DARPP32	protein phosphatase 1, regulatory (inhibitor) subunit 1B (EC:3.1.3.16)	C00001783
5621	PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30	prion protein	C00001783
57716	PRX, CMT4F	periaxin	C00001783
5695	PSMB7, Z	proteasome (prosome, macropain) subunit, beta type, 7 (EC:3.4.25.1)	C00001783
5740	PTGIS, CYP8, CYP8A1, PGIS, PTGI	prostaglandin I2 (prostacyclin) synthase (EC:5.3.99.4)	C00001783
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001783
2185	PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK	protein tyrosine kinase 2 beta (EC:2.7.10.2)	C00001783
5783	PTPN13, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (EC:3.1.3.48)	C00001783
84991	RBM17, SPF45	RNA binding motif protein 17	C00001783
56951	C5orf15, KCT2	chromosome 5 open reading frame 15	C00001781
6001	RGS10	regulator of G-protein signaling 10	C00001783
26575	RGS17, RGS-17, RGSZ2, hRGS17	regulator of G-protein signaling 17	C00001783
6095	RORA, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA	RAR-related orphan receptor A	C00001783
6128	RPL6, L6, SHUJUN-2, TAXREB107, TXREB1	ribosomal protein L6	C00001783
6240	RRM1, R1, RIR1, RR1	ribonucleotide reductase M1 (EC:1.17.4.1)	C00001783
864	RUNX3, AML2, CBFA3, PEBP2aC	runt-related transcription factor 3	C00001783
949	SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1	scavenger receptor class B, member 1	C00001783
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00001783
6442	SGCA, 50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	C00001783
7979	SHFM1, DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1	split hand/foot malformation (ectrodactyly) type 1	C00001783
6492	SIM1, bHLHe14	single-minded family bHLH transcription factor 1	C00001783
6555	SLC10A2, ASBT, IBAT, ISBT, NTCP2, PBAM	solute carrier family 10 (sodium/bile acid cotransporter), member 2	C00001783
9990	SLC12A6, ACCPN, KCC3, KCC3A, KCC3B	solute carrier family 12 (potassium/chloride transporter), member 6	C00001783
6584	SLC22A5, CDSP, OCTN2, OCTN2VT	solute carrier family 22 (organic cation/carnitine transporter), member 5	C00001783
9154	SLC28A1, CNT1, HCNT1	solute carrier family 28 (concentrative nucleoside transporter), member 1	C00001783
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00001783
28232	SLCO3A1, OATP-D, OATP3A1, OATPD, SLC21A11	solute carrier organic anion transporter family, member 3A1	C00001783
10592	SMC2, CAP-E, CAPE, SMC-2, SMC2L1	structural maintenance of chromosomes 2	C00001783
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00001783
6654	SOS1, GF1, GGF1, GINGF, HGF, NS4	son of sevenless homolog 1 (Drosophila)	C00001783
54908	SPDL1, CCDC99	spindle apparatus coiled-coil protein 1	C00001783
6716	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22)	C00001783
6717	SRI, CP-22, CP22, SCN, V19	sorcin	C00001783
6756	SSX1, CT5.1, SSRC	synovial sarcoma, X breakpoint 1	C00001783
6757	SSX2, CT5.2, CT5.2A, HD21, HOM-MEL-40, SSX	synovial sarcoma, X breakpoint 2	C00001783
6759	SSX4, CT5.4	synovial sarcoma, X breakpoint 4	C00001783
548313	SSX4B, CT5.4	synovial sarcoma, X breakpoint 4B	C00001783
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00001783
6820	SULT2B1, HSST2	sulfotransferase family, cytosolic, 2B, member 1 (EC:2.8.2.2)	C00001783
55530	SVOP	SV2 related protein homolog (rat)	C00001783
10732	TCFL5, CHA, E2BP-1, Figlb, bHLHe82	transcription factor-like 5 (basic helix-loop-helix)	C00001783
83660	TLN2, ILWEQ	talin 2	C00001783
50999	TMED5, CGI-100, p28	transmembrane emp24 protein transport domain containing 5	C00001783
26022	TMEM98	transmembrane protein 98	C00001783
944	TNFSF8, CD153, CD30L, CD30LG	tumor necrosis factor (ligand) superfamily, member 8	C00001783
7167	TPI1, TIM, TPI, TPID	triosephosphate isomerase 1 (EC:5.3.1.1)	C00001783
7173	TPO, MSA, TDH2A, TPX	thyroid peroxidase (EC:1.11.1.8)	C00001783
1200	TPP1, CLN2, LPIC, TPP-1	tripeptidyl peptidase I (EC:3.4.14.9)	C00001783
7223	TRPC4, HTRP-4, HTRP4, TRP4	transient receptor potential cation channel, subfamily C, member 4	C00001783
7251	TSG101, TSG10, VPS23	tumor susceptibility 101	C00001783
706	TSPO, BPBS, BZRP, DBI, IBP, MBR, PBR, PBS, PKBS, PTBR, mDRC, pk18	translocator protein (18kDa)	C00001783
1890	TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF	thymidine phosphorylase (EC:2.4.2.4)	C00001783
7298	TYMS, HST422, TMS, TS	thymidylate synthetase (EC:2.1.1.45)	C00001783
7350	UCP1, SLC25A7, UCP	uncoupling protein 1 (mitochondrial, proton carrier)	C00001783
7364	UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9	UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17)	C00001783
440279	UNC13C	unc-13 homolog C (C. elegans)	C00001783
7380	UPK3A, UP3A, UPIII, UPIIIA, UPK3	uroplakin 3A	C00001783
27340	UTP20, DRIM	UTP20, small subunit (SSU) processome component, homolog (yeast)	C00001783
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00001783
7481	WNT11, HWNT11	wingless-type MMTV integration site family, member 11	C00001783
51646	YPEL5	yippee-like 5 (Drosophila)	C00001783
169270	ZNF596	zinc finger protein 596 (EC:2.1.1.43)	C00001783
30834	ZNRD1, HTEX-6, Rpa12, TEX6, ZR14, hZR14, tctex-6	zinc ribbon domain containing 1 (EC:2.7.7.6)	C00001783

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions