KCF-S cluster No. 56 (71 metabolites)

Corresponding Phytochemical cluster No. 36

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (71)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	204

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Cumulative family count (Top 20)

class name	count
Lamiaceae	59
Rubiaceae	45
Verbenaceae	21
Plantaginaceae	16
Oleaceae	12
Acanthaceae	10
Loganiaceae	9
Caprifoliaceae	7
Bignoniaceae	3
Apocynaceae	3
Cornaceae	3
Menyanthaceae	2
Gentianaceae	2
Scrophulariaceae	2
Orobanchaceae	2
Tenebrionidae	1
Torricelliaceae	1
Griseliniaceae	1
Adoxaceae	1
Apiaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Iridoids	5

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metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Iridoids	C06071	C00003077
Iridoids	C09779	C00003081
Iridoids	C09784	C00003084
Iridoids	C01433	C00003088
Iridoids	C09802	C00003102

Metabolite list (71)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00003077	Deoxyloganin	CHEMBL2048533
C00003081	Gardenoside	CHEMBL485798 CHEMBL1079679 CHEMBL1482711 CHEMBL2133850	C056587	14 / 2 / 5
C00003084	Ipolamiide
C00003088	Loganin	CHEMBL1081584 CHEMBL1081586 CHEMBL1589904 CHEMBL2135791	C059516	2 / 1 / 1	0 / 1
C00003102	Cornin / Verbenalin	CHEMBL1080178 CHEMBL1375107	C000511	5 / 9 / 10
C00010473	Adoxoside / Dihydrogeniposide
C00010474	6beta-Hydroxyadoxoside / [1S-(1alpha,4aalpha,5alpha,7alpha,7aalpha)]-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexsahydro-5-hydroxy-7-(hydroxymethyl)-methyl ester
C00010482	Aralidioside
C00010550	Griselinoside
C00010555	10-Dehydrogardenoside
C00010570	8-Acetylharpagide / Harpagide 7-acetate / 8-O-Acetylharpagide	CHEMBL523290 CHEMBL595293	C077626	1 / 2 / 0
C00010573	Reptoside	CHEMBL518538
C00010576	Hastatoside
C00010578	Ipolamiidoside
C00010579	6beta-Hydroxyipolamiide
C00010580	Phlomiol	CHEMBL2048638 CHEMBL2048639	C099472
C00010589	Lamalbid / Lamalbide / Lamiridoside	CHEMBL1079619 CHEMBL2048642
C00010590	Lamiide
C00010595	Caryoptoside
C00010597	Lamioside
C00010598	6-Deoxylamioside
C00010601	Ajugoside	CHEMBL605532	C477173
C00010605	Ketologanin / Dehydrologanin
C00010618	Mollugoside
C00010628	Apodantheroside
C00010630	Mussaenoside	CHEMBL2355776		1 / 1 / 1
C00010657	Penstemonoside	CHEMBL518727	C091292
C00010658	Penstemoside / Pedicularioside	CHEMBL463960	C079206
C00010667	Pulchelloside I	CHEMBL1995139
C00010668	5-Deoxypulchelloside I	CHEMBL492202 CHEMBL1980462
C00010669	Randioside
C00010685	Sesamoside	CHEMBL2048637	C099471
C00010687	Shanzhiside methyl ester	CHEMBL1081414		1 / 1 / 1
C00010690	Barlerin / (-)-Barlerin / 8-O-Acetylshanzhiside methyl ester	CHEMBL463751 CHEMBL463377	C099473
C00010691	Acetylbarlerin
C00010692	6-O-Acetylshanzhiside methyl ester	CHEMBL2048640
C00010696	Strictoloside
C00010744	Diderroside
C00010745	Alpigenoside
C00010779	alpha-Morroniside	CHEMBL1209803 CHEMBL2136065 CHEMBL2152455		1 / 0 / 0
C00010791	Secogaliosdie
C00029570	6alpha-Hydroxyadoxoside
C00029571	6alpha-Hydroxyforsythide dimethyl ester
C00029704	Apodanthoside
C00029978	Citrifoside / (-)-Citrifoside
C00031802	Galioside	CHEMBL485798 CHEMBL1079679 CHEMBL1482711 CHEMBL2133850		14 / 2 / 5
C00031809	Genameside A / (-)-Genameside A
C00031810	Genameside B
C00033295	Phlomoside A / (-)-Phlomoside A
C00033296	Phlorigidoside C / (-)-Phlorigidoside C	CHEMBL2048531
C00035981	8-Epiloganin	CHEMBL1081584 CHEMBL1081586 CHEMBL1589904 CHEMBL2135791		2 / 1 / 1
C00036667	8-O-Acetylmussaenoside
C00037088	Eleganoside A
C00037089	Eleganoside B
C00037090	Eleganoside C
C00037513	Morroniside	CHEMBL1209803 CHEMBL2136065 CHEMBL2152455		1 / 0 / 0
C00037534	Myxopyroside
C00037566	Nyctanthoside / (-)-Nyctanthoside
C00037620	Phlorigidoside A / (-)-Phlorigidoside A
C00037621	Phlorigidoside B / (-)-Phlorigidoside B
C00038026	Yopaaoside C / (-)-Yopaaoside C
C00038286	5,9-epi-Penstemoside / (-)-5,9-epi-Penstemoside	CHEMBL463960
C00040760	10-Hydroxycornin / (-)-10-Hydroxycornin
C00040852	8-Epihastatoside
C00042395	Citrifolinin B epimer a	CHEMBL518691 CHEMBL517315
C00042396	Citrifolinin B epimer b	CHEMBL518691 CHEMBL517315
C00042991	Secologanoside dimethyl ester
C00043045	Stryspinoside / (-)-Stryspinoside
C00043217	6,9-Epi-8-O-acetylshanziside methyl ester / (-)-6,9-Epi-8-O-acetylshanziside methyl ester	CHEMBL463751 CHEMBL463377
C00044503	Adinoside A
C00048994	Gonocaryoside E / (-)-Gonocaryoside E

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00003081 C00003088 C00010779 C00031802 C00035981 C00037513	0 / 0
P60033	CD81 antigen	Unclassified protein	C00003088 C00010687 C00035981	1 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00003081 C00031802	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00003081 C00031802	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00003081 C00031802	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00003102 C00010570	2 / 0
P06746	DNA polymerase beta	Enzyme	C00003081 C00031802	0 / 0
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00003081 C00031802	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00003081 C00031802	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00003081 C00031802	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00003081 C00031802	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00003081 C00031802	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00003081 C00031802	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00003081 C00031802	1 / 4
Q9UBT6	DNA polymerase kappa	Enzyme	C00003081 C00031802	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00003081 C00031802	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003102	1 / 2
O00255	Menin	Unclassified protein	C00003102	2 / 5
P10636	Microtubule-associated protein tau	Unclassified protein	C00003102	4 / 3
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003102	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00010630	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions