KCF-S cluster No. 61 (69 metabolites)

Corresponding Phytochemical cluster No. 4

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (69)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	216

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Cumulative family count

class name	count
Apocynaceae	216

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Indole alkaloids	8

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metabolites link (9)

br08003 Category	KEGG ID	KNApSAcK ID
Indole alkaloids	C09034	C00001687
Indole alkaloids	C09244	C00001773
Indole alkaloids	C11676	C00024457
Indole alkaloids	C11812	C00024458
Indole alkaloids	C11783	C00024459
Indole alkaloids	C11783	C00024472
Indole alkaloids	C11643	C00024480
Indole alkaloids	C11675	C00024481
Indole alkaloids	C11642	C00024501

Metabolite list (69)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001687	Apodine
C00001773	Tabersonine	CHEMBL1971886 CHEMBL2011511	C009373
C00024450	(-)-12-Hydroxyvincadifformine
C00024457	Lochnericine / (-)-Lochnericine	CHEMBL2011514
C00024458	Hazuntine / (-)-Hazuntine / (-)-Lochnerinine
C00024459	(-)-Minovincinine
C00024463	Vincadifformine / (-)-Vincadifformine / 6,7-Dihydrotabersonine	CHEMBL251690 CHEMBL1617045	C456406
C00024472	Alkaloid V3 / (+)-Minovincinine / 20R-20-Hydroxy-(-)-vincadifformine
C00024478	11,19R-Dihydroxytabersonine
C00024479	11-Hydroxy-14,15-epoxytabersonine / 11-Hydroxy-14,15alpha-epoxytabersonine
C00024480	11-Hydroxytabersonine	CHEMBL2011510
C00024481	11-Methoxytabersonine / 16-Methoxytabersonine / (-)-11-Methoxytabersonine	CHEMBL1165751
C00024482	11-Methoxyvincadifformine / 6,7-Dihydro-11-methoxytabersonine
C00024488	14,15-Dihydroxyvincadifformine
C00024491	15beta-Hydroxyvincadifformine / (+)-6beta-Hydroxyvincadifformine
C00024499	Vandrikidine / 19R-Hydroxy-11-methoxy-tabersonine	CHEMBL2011513
C00024500	19R-epimisiline / 19R-Hydroxypachysiphine
C00024501	19R-Hydroxytabersonine
C00024502	19S-Acetoxy-3-oxotabersonine / 20(S)-Acetoxy-8-oxotabersonine
C00024503	19S-Acetoxytabersonine / 20(S)-Acetoxytabersonine	CHEMBL2011512
C00024504	19R-epimisiline / 19S-Hydroxypachysiphine
C00024508	3-Oxotabersonine / 8-Oxotabersonine / (-)-3-Oxotabersonine
C00024510	3-Oxovincadifformine / (-)-3-Oxovincadifformine
C00024514	Apodinine / 14-Hydroxyapodine
C00024522	Buxomeline
C00024524	Cathovalinine
C00024537	Hedrantherine
C00024582	Modestanine / Modestamine / Deoxoapodine / Demethoxyvandrikine
C00024587	Pachysiphine / (-)-Pachysiphine	CHEMBL2011514
C00024592	Petchicine / (-)-Petchicine
C00024610	Vandrikin / Vandrikine
C00025176	Hydroxy-19,20-dihydroakuammicine	CHEMBL1651105 CHEMBL1651106
C00025216	Tubotaiwine / Methyl (14beta)-2,16-didehydrocondyfolan-16-carboxylate	CHEMBL508920	C404563
C00025404	(+)-19-Hydroxy-20-epi-pandoline
C00025405	(+)-(20R)-18,19-Dihydroxy-y-vincadifformine / (+)-20R-18,19-dihydroxy-pseudovincadifformine
C00025406	20R-Pseudovincadifformine / (+)-20R-Pseudovincadifformine
C00025407	18-Hydroxy-20-epiibophyllidine / 18-Hydroxy-20-epi-ibophyllidine
C00025408	19-Hydroxyibophyllidine
C00025409	20-Epi-ibophyllidine / (+)-20-Epiibophyllidine
C00025410	Epipandoline / 7-Epipandoline / 20-Epipandoline / 20-epi-Pandoline / (+)-20-Epipandoline
C00025411	20S-Pseudovincadifformine
C00025412	Desethylibophyllidine
C00025415	Pandine / (+)-Pandine
C00025416	Pandoline / (+)-Pandoline / (+)-7alpha-Hydroxy pseudovincadifformine
C00025690	(+)-Vincadifformine / 5beta,12alpha,19beta-Vincadifformine	CHEMBL251690 CHEMBL1617045
C00025715	12-Hydroxyvincadifformine / (-)-17-Hydroxyvincadifformine
C00025735	20-Epilochneridine
C00025887	Hazuntinin / Hazuntinine	CHEMBL525066
C00025895	Ibophyllidine
C00025945	Minovincine / (+)-Minovincine
C00027061	Lagumicine / 19-Dehydrocompactinervine
C00027079	Alstovine
C00027704	19alpha,20alpha-Epoxyakuammicine
C00028082	Compactinervine
C00038181	19(R)-Methoxytubotaiwine	CHEMBL251650 CHEMBL400176
C00038182	19(S)-Methoxytubotaiwine / (+)-19(S)-Methoxytubotaiwine	CHEMBL251650 CHEMBL400176
C00039490	Jerantinine A / (-)-Jerantinine A	CHEMBL497669
C00039491	Jerantinine B / (-)-Jerantinine B	CHEMBL446954
C00039492	Jerantinine C / (-)-Jerantinine C	CHEMBL524639
C00039493	Jerantinine D / (-)-Jerantinine D	CHEMBL525919
C00039494	Jerantinine E / (-)-Jerantinine E	CHEMBL496470
C00039495	Jerantinine F / (-)-Jerantinine F	CHEMBL524840
C00041239	12-Methoxyechitamidine / (-)-12-Methoxyechitamidine	CHEMBL523826 CHEMBL1651107
C00041240	12-Methoxytubotaiwine
C00041510	Echitamidine	CHEMBL1651105 CHEMBL1651106	C085228
C00041685	N(4)-Demethyl-12-methoxyalstogustine / (-)-N(4)-Demethyl-12-methoxyalstogustine	CHEMBL523826 CHEMBL1651107
C00047645	19-Acetoxy-11-methoxytabersonine
C00047713	Alstoyunine G / (-)-Alstoyunine G	CHEMBL1078197		3 / 0 / 3
C00047714	Alstoyunine H / (-)-Alstoyunine H	CHEMBL1078382		3 / 0 / 3

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00047713 C00047714	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00047713 C00047714	0 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00047713 C00047714	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions