Petiveria alliacea
Species
KNApSAcK Entry
| Organism name | Petiveria alliacea |
|---|---|
| Genus | Petiveria |
| Family | Phytolaccaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Petiveria alliacea |
|---|---|
| Linked NCBI taxonomy ID | 46142 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Petiveriaceae |
|---|---|
| ID | 441552 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Natural Activity
List (86)
| Species | Activity |
|---|---|
| Petiveria alliacea L. | Abortifacient |
| Petiveria alliacea L. | Abortifacient |
| Petiveria alliacea L. | Analgesic |
| Petiveria alliacea L. | Analgesic |
| Petiveria alliacea L. | Anesthetic |
| Petiveria alliacea L. | Anesthetic |
| Petiveria alliacea L. | Antiaggregant |
| Petiveria alliacea L. | Antidote |
| Petiveria alliacea L. | Antifertility |
| Petiveria alliacea L. | Antiherpetic |
| Petiveria alliacea L. | Antiinflammatory |
| Petiveria alliacea L. | Antiinflammatory |
| Petiveria alliacea L. | Antileukemic |
| Petiveria alliacea L. | Antilymphomic |
| Petiveria alliacea L. | Antimitotic |
| Petiveria alliacea L. | Antimitotic |
| Petiveria alliacea L. | Antioxidant |
| Petiveria alliacea L. | Antipyretic |
| Petiveria alliacea L. | Antiradicular |
| Petiveria alliacea L. | Antiseptic |
| Petiveria alliacea L. | Antiseptic |
| Petiveria alliacea L. | Antispasmodic |
| Petiveria alliacea L. | Antispasmodic |
| Petiveria alliacea L. | Antitrypanosomic |
| Petiveria alliacea L. | Antitumor |
| Petiveria alliacea L. | Antitumor |
| Petiveria alliacea L. | Antitussive |
| Petiveria alliacea L. | Antitussive |
| Petiveria alliacea L. | Antiviral |
| Petiveria alliacea L. | Anxiolytic |
| Petiveria alliacea L. | Aphrodisiac |
| Petiveria alliacea L. | Aphrodisiac |
| Petiveria alliacea L. | Bactericide |
| Petiveria alliacea L. | Candidicide |
| Petiveria alliacea L. | Candidicide |
| Petiveria alliacea L. | CNS Depressant |
| Petiveria alliacea L. | CNS-Depressant |
| Petiveria alliacea L. | Contraceptive |
| Petiveria alliacea L. | Contraceptive |
| Petiveria alliacea L. | Cyclooxygenase Inhibitor |
| Petiveria alliacea L. | Cyclooxygenase-Inhibitor |
| Petiveria alliacea L. | Cytotoxic |
| Petiveria alliacea L. | Depurative |
| Petiveria alliacea L. | Depurative |
| Petiveria alliacea L. | Diaphoretic |
| Petiveria alliacea L. | Diaphoretic |
| Petiveria alliacea L. | Diuretic |
| Petiveria alliacea L. | Diuretic |
| Petiveria alliacea L. | Emmenagogue |
| Petiveria alliacea L. | Emmenagogue |
| Petiveria alliacea L. | Expectorant |
| Petiveria alliacea L. | Expectorant |
| Petiveria alliacea L. | Febrifuge |
| Petiveria alliacea L. | Fungicide |
| Petiveria alliacea L. | Hallucinogenic |
| Petiveria alliacea L. | Hypoglycemic |
| Petiveria alliacea L. | Hypoglycemic |
| Petiveria alliacea L. | Immunostimulant |
| Petiveria alliacea L. | Immunostimulant |
| Petiveria alliacea L. | Insecticide |
| Petiveria alliacea L. | Insecticide |
| Petiveria alliacea L. | Insectifuge |
| Petiveria alliacea L. | Insectifuge |
| Petiveria alliacea L. | Lachrymatory |
| Petiveria alliacea L. | Lymphocytogenic |
| Petiveria alliacea L. | Mitogenic |
| Petiveria alliacea L. | Mutagenic |
| Petiveria alliacea L. | Mutagenic |
| Petiveria alliacea L. | Narcotic |
| Petiveria alliacea L. | Nematicide |
| Petiveria alliacea L. | Nematocide |
| Petiveria alliacea L. | Nervine |
| Petiveria alliacea L. | Nervine |
| Petiveria alliacea L. | Pediculicide |
| Petiveria alliacea L. | Phagocytotic |
| Petiveria alliacea L. | Phagocytotic |
| Petiveria alliacea L. | Protisticide |
| Petiveria alliacea L. | Sedative |
| Petiveria alliacea L. | Sternutatory |
| Petiveria alliacea L. | Sudorific |
| Petiveria alliacea L. | Tonic |
| Petiveria alliacea L. | Trypanocide |
| Petiveria alliacea L. | Uterotonic |
| Petiveria alliacea L. | Uterotonic |
| Petiveria alliacea L. | Vermifuge |
| Petiveria alliacea L. | Vermifuge |
Metabolite list (14)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00008482
|
Leridol
|
No. 25 | No. 14 |
|
||||
|
C00008481
|
Leridal
|
CHEMBL1271363
|
No. 25 | No. 14 |
|
|||
|
C00008483
|
5-O-Methylleridol
|
No. 25 | No. 14 |
|
||||
|
C00029811
|
Benzyl alcohol
/ (Hydroxymethyl)benzene |
CHEMBL720
|
D019905
|
94 / 41 / 36 | 1 / 6 | No. 885 |
|
|
|
C00014419
|
Leridal chalcone
/ (E)-2,4-Dihydroxy-6-methoxy-5-methyl-3-(1-oxo-3-phenyl-2-propenyl)benzaldehyde |
No. 1043 |
|
|||||
|
C00000207
|
Benzoic acid
|
CHEMBL541
|
D019817
|
97 / 39 / 33 | 24 / 1 | No. 2192 |
|
|
|
C00019221
|
Benzyl benzoate
|
CHEMBL1239
|
C006723
|
12 / 5 / 8 | 3 / 2 | No. 2308 |
|
|
|
C00037792
|
S-Benzyl-L-cysteine sulfoxide
|
No. 3303 |
|
|||||
|
C00015883
|
Stilbene
|
CHEMBL113028
CHEMBL393702 |
2 / 2 / 2 | No. 3909 |
|
|||
|
C00037932
|
trans-Stilbene
|
CHEMBL113028
CHEMBL393702 |
2 / 2 / 2 | No. 3909 |
|
|||
|
C00037047
|
Dibenzyl trisulfide
|
CHEMBL378770
|
No. 3974 |
|
||||
|
C00037046
|
Benzyl disulfide
/ Dibenzyl disulfide |
CHEMBL121047
|
C478857
|
No. 3974 |
|
|||
|
C00037959
|
Trithiolaniacin
|
No. 3974 |
|
|||||
|
C00034452
|
Benzaldehyde
|
CHEMBL15972
|
C032175
|
8 / 7 / 3 | 3 / 1 | No. 6311 |
|
Human Protein / Gene in interactions
116 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000207 C00015883 C00029811 C00037932 | 2 / 2 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000207 C00029811 C00034452 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000207 C00029811 C00034452 | 1 / 1 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000207 C00019221 C00029811 | 1 / 1 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000207 C00029811 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000207 C00029811 | 1 / 0 |
| P08246 | Neutrophil elastase | S1A | C00000207 C00029811 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000207 C00029811 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000207 C00029811 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000207 C00029811 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000207 C00029811 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000207 C00029811 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000207 C00029811 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000207 C00029811 | 0 / 1 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000207 C00029811 | 2 / 2 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000207 C00029811 | 1 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000207 C00029811 | 3 / 2 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000207 C00029811 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000207 C00029811 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000207 C00029811 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000207 C00029811 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000207 C00029811 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000207 C00029811 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000207 C00029811 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000207 C00029811 | 0 / 0 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000207 C00029811 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000207 C00029811 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000207 C00029811 | 0 / 1 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000207 C00029811 | 1 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000207 C00029811 | 1 / 8 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00019221 C00029811 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000207 C00029811 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000207 C00029811 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000207 C00029811 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000207 C00029811 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000207 C00029811 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000207 C00029811 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000207 C00029811 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000207 C00029811 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000207 C00029811 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000207 C00029811 | 1 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000207 C00029811 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000207 C00029811 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000207 C00029811 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000207 C00029811 | 0 / 1 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000207 C00029811 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000207 C00029811 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000207 C00029811 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000207 C00029811 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000207 C00029811 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000207 C00029811 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000207 C00029811 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000207 C00029811 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000207 C00029811 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000207 C00029811 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000207 C00029811 | 1 / 1 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000207 C00029811 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000207 C00029811 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000207 C00029811 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000207 C00029811 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000207 C00029811 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000207 C00029811 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000207 C00029811 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000207 C00029811 | 0 / 3 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000207 C00029811 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000207 C00029811 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000207 C00029811 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000207 C00029811 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000207 C00029811 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000207 C00029811 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000207 C00029811 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000207 C00029811 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000207 C00029811 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000207 C00029811 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000207 C00029811 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000207 C00029811 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000207 C00029811 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000207 C00029811 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000207 C00029811 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000207 C00029811 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000207 C00029811 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000207 C00029811 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000207 C00029811 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000207 C00029811 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00015883 C00037932 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000207 C00029811 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000207 C00029811 | 1 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000207 C00029811 | 2 / 1 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00019221 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00034452 | 4 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00019221 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00019221 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00019221 | 1 / 2 |
| Q9GZT4 | Serine racemase | Enzyme | C00000207 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00034452 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00034452 | 2 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00034452 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00019221 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00034452 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00029811 | 2 / 3 |
| P14920 | D-amino-acid oxidase | Enzyme | C00000207 | 0 / 0 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000207 | 0 / 0 |
| P40925 | Malate dehydrogenase, cytoplasmic | Enzyme | C00019221 | 0 / 0 |
| P30556 | Type-1 angiotensin II receptor | Angiotensin receptor | C00019221 | 1 / 1 |
| Q99489 | D-aspartate oxidase | Enzyme | C00000207 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00034452 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000207 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00019221 | 1 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00019221 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00019221 | 1 / 4 |
30 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 231 | AKR1B1, ADR, ALDR1, ALR2, AR | aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) |
C00000207
C00029811
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00000207
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00019221
|
| 217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) |
C00034452
|
| 218 | ALDH3A1, ALDH3, ALDHIII | aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5) |
C00034452
|
| 221 | ALDH3B1, ALDH4, ALDH7 | aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5) |
C00034452
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00019221
|
| 57016 | AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI | aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) |
C00000207
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000207
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000207
|
| 2235 | FECH, EPP, FCE | ferrochelatase (EC:4.99.1.1) |
C00000207
|
| 2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00000207
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00000207
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00000207
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00000207
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00019221
|
| 2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00000207
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000207
|
| 4097 | MAFG, hMAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
C00000207
|
| 4199 | ME1, HUMNDME, MES | malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) |
C00000207
|
| 4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00000207
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00000207
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000207
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00000207
|
| 5226 | PGD, 6PGD | phosphogluconate dehydrogenase (EC:1.1.1.44) |
C00000207
|
| 22949 | PTGR1, LTB4DH, PGR1, ZADH3 | prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) |
C00000207
|
| 6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00000207
|
| 140809 | SRXN1, C20orf139, Npn3, SRX, SRX1 | sulfiredoxin 1 (EC:1.8.98.2) |
C00000207
|
| 7295 | TXN, TRDX, TRX, TRX1 | thioredoxin |
C00000207
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00000207
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (51)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #267430 | Renal tubular dysgenesis; rtd |
P30556
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (45)
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H00575 | Renal tubular dysgenesis |
P30556
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
Diseases related to CTD interactions
9 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D003877 | Dermatitis, Contact |
C00019221
C00000207 |
| D017453 | Dermatitis, Irritant |
C00029811
|
| D012640 | Seizures |
C00034452
|
| D001145 | Arrhythmias, Cardiac |
C00029811
|
| D012532 | Scabies |
C00019221
|
| D004342 | Drug Hypersensitivity |
C00029811
|
| D007022 | Hypotension |
C00029811
|
| D010264 | Paraplegia |
C00029811
|
| D011843 | Radiculopathy |
C00029811
|