PCIDB

KCF-S cluster No. 2308 (5 metabolites)

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00019221 External link 512 Benzyl benzoate
CHEMBL1239
C006723
12 / 5 / 8 3 / 2
C00019222 External link 512 Benzyl trans-cinnamate
CHEMBL361197
CHEMBL2361576
3 / 11 / 10
C00035016 External link 512 2-Phenylethyl benzoate
C00035059 External link 512 Benzyl salicylate
CHEMBL460124
C039672
9 / 6 / 4 3 / 0
C00041375 External link 512 Benzyl 2-hydroxy-6-methoxybenzoate
CHEMBL451295
1 / 0 / 0

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00019221 C00019222 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00019221 C00035059 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00019221 C00035059 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00019221 C00035059 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00019221 C00035059 0 / 0
P35610 Sterol O-acyltransferase 1 Enzyme C00041375 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00019221 1 / 1
O75496 Geminin Unclassified protein C00035059 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00019221 1 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00035059 3 / 1
P40925 Malate dehydrogenase, cytoplasmic Enzyme C00019221 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00019221 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00035059 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00035059 0 / 0
P30556 Type-1 angiotensin II receptor Angiotensin receptor C00019221 1 / 1
P02545 Prelamin-A/C Unclassified protein C00019222 11 / 10
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00019222 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00035059 2 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00019221 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00019221 1 / 4

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00019221 C00035059
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00019221 C00035059
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00019221 C00035059

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613688 Long qt syndrome 2; lqt2 Q12809
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#267430 Renal tubular dysgenesis; rtd P30556
#275210 Restrictive dermopathy, lethal P02545
#609620 Short qt syndrome 1; sqt1 Q12809
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (21)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00575 Renal tubular dysgenesis P30556 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003877 Dermatitis, Contact C00019221
D012532 Scabies C00019221