KNApSAcK Metabolite C00035059
Metabolite
KNApSAcK Entry
| id | C00035059 |
|---|---|
| Name | Benzyl salicylate |
| CAS RN | 118-58-1 |
| Standard InChI | InChI=1S/C14H12O3/c15-13-9-5-4-8-12(13)14(16)17-10-11-6-2-1-3-7-11/h1-9,15H,10H2 |
| Standard InChI (Main Layer) | InChI=1S/C14H12O3/c15-13-9-5-4-8-12(13)14(16)17-10-11-6-2-1-3-7-11/h1-9,15H,10H2 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 2308 |
Link
ChEMBL
| By standard InChI | CHEMBL460124 |
|---|---|
| By standard InChI Main Layer | CHEMBL460124 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C039672 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| asterids | 1 |
Family
| family name | count |
|---|---|
| Solanaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Nicotiana cavicola | 118690 | Solanaceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
9 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL460124 |
CHEMBL1794573
(1)
|
2 / 2 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | CHEMBL460124 |
CHEMBL1794399
(1)
|
3 / 1 |
| O75496 | Geminin | Unclassified protein | CHEMBL460124 |
CHEMBL2114780
(1)
|
0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL460124 |
CHEMBL1794401
(1)
|
0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | CHEMBL460124 |
CHEMBL2114842
(1)
|
0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL460124 |
CHEMBL1738588
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL460124 |
CHEMBL1737991
(1)
|
0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL460124 |
CHEMBL2114890
(1)
|
0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | CHEMBL460124 |
CHEMBL1614364
(2)
|
1 / 1 |
CTD interaction (4)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C039672 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | benzyl salicylate inhibits the reaction [Estradiol binds to ESR1 protein] |
affects binding
/ decreases reaction |
protein |
19338011
|
| C039672 | 2099 |
ESR1
ER ESR ESRA ESTRR Era NR3A1 |
estrogen receptor 1 | benzyl salicylate results in increased activity of ESR1 protein |
increases activity
|
protein |
22197706
|
| C039672 | 2100 |
ESR2
ER-BETA ESR-BETA ESRB ESTRB Erb NR3A2 |
estrogen receptor 2 (ER beta) | benzyl salicylate inhibits the reaction [Estradiol binds to ESR2 protein] |
affects binding
/ decreases reaction |
protein |
19338011
|
| C039672 | 7031 |
TFF1
BCEI D21S21 HP1.A HPS2 pNR-2 pS2 |
trefoil factor 1 | benzyl salicylate results in increased expression of TFF1 mRNA |
increases expression
|
mRNA |
19338011
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|