Nicotiana cavicola
Species
KNApSAcK Entry
| Organism name | Nicotiana cavicola |
|---|---|
| Genus | Nicotiana |
| Family | Solanaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Nicotiana cavicola |
|---|---|
| Linked NCBI taxonomy ID | 118690 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Solanaceae |
|---|---|
| ID | 4070 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00035115
|
Benzenepropanol
/ 3-Phenylpropanol / Hydrocinnamic alcohol |
CHEMBL1606391
|
C016655
|
3 / 1 / 4 | No. 885 |
|
||
|
C00035128
|
m-Cresol
/ m-Oxytoluene |
CHEMBL298312
|
C042041
|
6 / 4 / 1 | 1 / 3 | No. 1546 |
|
|
|
C00035059
|
Benzyl salicylate
|
CHEMBL460124
|
C039672
|
9 / 6 / 4 | 3 / 0 | No. 2308 |
|
|
|
C00019221
|
Benzyl benzoate
|
CHEMBL1239
|
C006723
|
12 / 5 / 8 | 3 / 2 | No. 2308 |
|
|
|
C00034054
|
Methyl benzoate
|
CHEMBL16435
|
C044605
|
4 / 6 / 6 | No. 4170 |
|
Human Protein / Gene in interactions
25 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00019221 C00034054 C00035059 C00035128 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00035115 C00035128 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00019221 C00035059 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00035059 C00035128 | 3 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00019221 C00035115 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00019221 C00035115 | 1 / 4 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00019221 C00035059 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00019221 C00035059 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003110 C00019221 | 1 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00019221 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00035059 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00035128 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00034054 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00019221 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00035059 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00035059 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00035128 | 1 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00019221 | 1 / 1 |
| P40925 | Malate dehydrogenase, cytoplasmic | Enzyme | C00019221 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00034054 | 3 / 4 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00035128 | 0 / 0 |
| P30556 | Type-1 angiotensin II receptor | Angiotensin receptor | C00019221 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003110 | 2 / 5 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00034054 | 3 / 2 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00035059 | 2 / 2 |
4 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00019221
C00035059
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00019221
C00035059
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00019221
C00035059
|
| 6329 | SCN4A, HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1 | sodium channel, voltage-gated, type IV, alpha subunit |
C00035128
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (19)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #267430 | Renal tubular dysgenesis; rtd |
P30556
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (22)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00575 | Renal tubular dysgenesis |
P30556
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|