Combretum quadrangulare

• Index
• Plant Species
• Metabolite list (48)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Combretum quadrangulare
Genus	Combretum
Family	Combretaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Combretum
Linked NCBI taxonomy ID	99434
Linked level	genus

Family

Family in NCBI taxonomy	Combretaceae
ID	3954

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (48)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001062	Isokaempferide / Kaempferol 3-methyl ether / 5,7,4'-trihydroxy-3-methoxyflavone	CHEMBL165064		19 / 4 / 3		No. 3	No. 15
C00004569	Jaranol / Kumatakenin / Kumatakillin / Kaempferol 3,7-O-dimethyl ether / 5,4'-Dihydroxy-3,7-dimethoxyflavone / 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL349724				No. 3	No. 15
C00004777	Combretol / 5-Hydroxy-3,3',4',5',7-pentamethoxyflavone / 5-Hydroxy-3,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL518300				No. 8	No. 15
C00004775	Myricetin 3,7,3',5'-tetramethyl ether					No. 8	No. 15
C00045579	6beta-Hydroxyarjunic acid	CHEMBL475889				No. 13	No. 51
C00029724	Arjunolic acid	CHEMBL464466 CHEMBL1774425 CHEMBL1797308	C061640	2 / 0 / 0	0 / 2	No. 13	No. 51
C00045663	Arjunic acid	CHEMBL515705				No. 13	No. 51
C00029412	19alpha-Hydroxyasiatic acid	CHEMBL515920				No. 13	No. 51
C00035051	Arjungenin / (+)-Arjungenin	CHEMBL499598 CHEMBL1078651 CHEMBL1078652				No. 13	No. 51
C00001110	Vitexin / Apigenin 8-C-glucoside / 8-D-Glucosyl-4',5,7-trihydroxyflavone / 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL487417 CHEMBL1332209 CHEMBL1357921		16 / 4 / 8		No. 22	No. 15
C00045580	6beta-Hydroxyhovenic acid	CHEMBL472852				No. 23	No. 51
C00047085	Quadranoside V / (+)-Quadranoside V	CHEMBL500700				No. 50	No. 51
C00046341	Quadranoside IV / (+)-Quadranoside IV	CHEMBL500352 CHEMBL1956941				No. 50	No. 51
C00046340	Quadranoside II / (+)-Quadranoside II	CHEMBL502086				No. 50	No. 51
C00047080	Pinfaensin		C090265			No. 50	No. 51
C00040129	Quadranoside III / (+)-Quadranoside III					No. 50	No. 51
C00032626	28-O-beta-D-glucopyranosyl-6beta,23-dihydroxytormentic acid					No. 50	No. 51
C00032735	Arjunetin / 24-Deoxysericoside		C484967			No. 50	No. 51
C00032736	Arjunglucoside II / Arjunoglucoside II / (+)-Arjunoglucoside II					No. 50	No. 51
C00032809	Chebuloside II	CHEMBL391767				No. 50	No. 51
C00032852	Combreglucoside					No. 50	No. 51
C00035052	Arjunglucoside I / (+)-Arjunglucoside I	CHEMBL446040				No. 50	No. 51
C00033332	Quadranoside VI / (+)-Quadranoside VI					No. 50	No. 51
C00033333	Quadranoside VII / (+)-Quadranoside VII					No. 50	No. 51
C00047084	Quadranoside I / (+)-Quadranoside I	CHEMBL510768				No. 50	No. 51
C00033335	Quadranoside X / (+)-Quadranoside X					No. 50	No. 51
C00033334	Quadranoside VIII / (+)-Quadranoside VIII	CHEMBL1077634				No. 50	No. 51
C00000947	D-Catechol / D-Catechin / Teafuran 30A / (+)-Catechin / Dexcyanidanol / (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol	CHEMBL80941 CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912	D002392	85 / 58 / 54	91 / 13	No. 52	No. 14
C00000956	(-)-Epicatechin	CHEMBL80941 CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912		85 / 58 / 54		No. 52	No. 14
C00008818	Epigallocatechin / (-)-Epigallocatechin	CHEMBL47386 CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845		26 / 17 / 29		No. 52	No. 14
C00008817	Gallocatechin / (+)-Gallocatechin / (+)-Gallocatechol / (2R,3S)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol	CHEMBL47386 CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845		26 / 17 / 29		No. 52	No. 14
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00008866	(-)-Epicatechin gallate / (-)-Epicatechin 3-O-gallate	CHEMBL36327 CHEMBL78573 CHEMBL328085 CHEMBL126142 CHEMBL129451 CHEMBL483083 CHEMBL1514905		41 / 20 / 30		No. 219	No. 14
C00046872	Quadrangularic acid J / (+)-Quadrangularic acid J	CHEMBL472834				No. 415
C00046874	Quadrangularic acid M / (+)-Quadrangularic acid M					No. 415
C00046573	24-Epiquadrangularic acid G / (+)-24-Epiquadrangularic acid G	CHEMBL500032 CHEMBL453000				No. 415
C00046590	7beta-Hydroxy-23-deoxojessic acid	CHEMBL473451				No. 415
C00046873	Quadrangularic acid L / (+)-Quadrangularic acid L	CHEMBL473039 CHEMBL514459				No. 415
C00046834	Norquadrangularic acid A / (+)-Norquadrangularic acid A	CHEMBL479490				No. 415
C00046869	Quadrangularic acid F / (+)-Quadrangularic acid F	CHEMBL462353				No. 415
C00046870	Quadrangularic acid G / (+)-Quadrangularic acid G	CHEMBL500032 CHEMBL453000				No. 415
C00046871	Quadrangularic acid H / (+)-Quadrangularic acid H	CHEMBL515770				No. 415
C00046822	Methyl quadrangularate I / (+)-Methyl quadrangularate I	CHEMBL475877				No. 415
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00002647	Gallic acid	CHEMBL288114	D005707	42 / 53 / 68	52 / 16	No. 817	No. 81
C00030754	Methyl gallate / Methyl 3,4,5-trihydroxybenzoate	CHEMBL65675	C052082	16 / 15 / 13		No. 1722
C00033331	Quadranoside IX / (+)-Quadranoside IX					No. 5434
C00033336	Quadranoside XI / (+)-Quadranoside XI					No. 5434

Human Protein / Gene in interactions

128 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000947 C00000956 C00001062 C00001110 C00002647 C00008817 C00008818 C00008866 C00030754	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000947 C00000956 C00001062 C00001110 C00002647 C00008817 C00008818 C00008866	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000947 C00000956 C00002647 C00003672 C00008817 C00008818 C00008866 C00030754	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000947 C00000956 C00001062 C00002647 C00008817 C00008818 C00008866 C00030754	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00000947 C00000956 C00002647 C00008817 C00008818 C00008866	2 / 3
P11473	Vitamin D3 receptor	NR1I1	C00000947 C00000956 C00002647 C00008817 C00008818 C00008866	2 / 3
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000947 C00000956 C00001062 C00008817 C00008818 C00008866	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000947 C00000956 C00002647 C00008817 C00008818 C00008866	4 / 3
P02768	Serum albumin	Secreted protein	C00000947 C00000956 C00008817 C00008818 C00008866 C00030754	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000947 C00000956 C00002647 C00008817 C00008818 C00008866	3 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000947 C00000956 C00001062 C00001110 C00003672 C00008866	0 / 1
P06746	DNA polymerase beta	Enzyme	C00000947 C00000956 C00001062 C00003672 C00019308 C00030754	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
P00374	Dihydrofolate reductase	Oxidoreductase	C00000947 C00000956 C00008817 C00008818 C00008866	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000947 C00000956 C00002647 C00008817 C00008818	2 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000947 C00000956 C00002647 C00008817 C00008818	0 / 3
P56817	Beta-secretase 1	A1A	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
P52209	6-phosphogluconate dehydrogenase, decarboxylating	Enzyme	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 7
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000947 C00000956 C00008817 C00008818 C00030754	1 / 1
P41143	Delta-type opioid receptor	Opioid receptor	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000947 C00000956 C00002647 C00008817 C00008818	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000947 C00000956 C00001062 C00002647 C00030754	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000947 C00000956 C00001062 C00001110 C00003672	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000947 C00000956 C00008817 C00008818 C00008866	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000947 C00000956 C00001062 C00030754	0 / 0
P00734	Prothrombin	S1A	C00000947 C00000956 C00003672 C00019308	4 / 2
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000947 C00000956 C00001110 C00003672	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000947 C00000956 C00001062 C00001110	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00000947 C00000956 C00001062 C00001110	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000947 C00000956 C00003672 C00019308	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00000947 C00000956 C00001062 C00030754	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000947 C00000956 C00001110 C00003672	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000947 C00000956 C00001110 C00003672	1 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000947 C00000956 C00008817 C00008818	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000947 C00000956 C00008866	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000947 C00000956 C00002647	0 / 0
P41743	Protein kinase C iota type	Iota	C00000947 C00000956 C00008866	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000947 C00000956 C00002647	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000947 C00000956 C00030754	1 / 1
P24723	Protein kinase C eta type	Eta	C00000947 C00000956 C00008866	1 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000947 C00000956 C00002647	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001110 C00008817 C00008818	1 / 4
P05129	Protein kinase C gamma type	Alpha	C00000947 C00000956 C00008866	1 / 1
O43570	Carbonic anhydrase 12	Lyase	C00000947 C00000956 C00002647	1 / 2
P22748	Carbonic anhydrase 4	Lyase	C00000947 C00000956 C00002647	1 / 1
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000947 C00000956 C00002647	3 / 0
P17252	Protein kinase C alpha type	Alpha	C00000947 C00000956 C00008866	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00000947 C00000956 C00002647	4 / 1
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000947 C00000956 C00008866	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00000947 C00000956 C00008866	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000947 C00000956 C00002647	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000947 C00000956 C00002647	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00000947 C00000956 C00008866	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000947 C00000956 C00002647	0 / 0
O00255	Menin	Unclassified protein	C00000947 C00000956 C00008866	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000947 C00000956 C00008866	1 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00000947 C00000956 C00003672	3 / 2
P43166	Carbonic anhydrase 7	Lyase	C00000947 C00000956 C00002647	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000947 C00000956 C00002647	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000947 C00000956 C00002647	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001110 C00008817 C00008818	0 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000947 C00000956 C00002647	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000947 C00000956 C00002647	5 / 1
Q04759	Protein kinase C theta type	Delta	C00000947 C00000956 C00008866	0 / 1
Q05513	Protein kinase C zeta type	Iota	C00000947 C00000956 C00008866	0 / 0
P05771	Protein kinase C beta type	Alpha	C00000947 C00000956 C00008866	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00000947 C00000956	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001110 C00030754	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00000947 C00000956	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000947 C00000956	0 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00001062 C00030754	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001110 C00030754	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000947 C00000956	3 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000947 C00000956	0 / 0
P07711	Cathepsin L1	C1A	C00000947 C00000956	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00019308	0 / 0
P15121	Aldose reductase	Enzyme	C00001110 C00002647	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000947 C00000956	5 / 2
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000947 C00000956	3 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000947 C00000956	0 / 1
P03372	Estrogen receptor	NR3A1	C00002647 C00003672	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000947 C00000956	2 / 0
P07998	Ribonuclease pancreatic	Enzyme	C00000947 C00000956	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000947 C00000956	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000947 C00000956	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002647 C00030754	11 / 10
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000947 C00000956	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001062 C00002647	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00000947 C00000956	1 / 2
P49327	Fatty acid synthase	Transferase	C00000947 C00000956	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001110 C00002647	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00000947 C00000956	1 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001062 C00030754	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000947 C00000956	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00019308	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
P16109	P-selectin	Adhesion	C00002647	1 / 0
P14151	L-selectin	Adhesion	C00002647	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00008866	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672	2 / 0
Q07817	Bcl-2-like protein 1	Other cytosolic protein	C00001062	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00008866	1 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00001062	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002647	7 / 37
P12821	Angiotensin-converting enzyme	M2	C00002647	4 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001062	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00008866	0 / 0
P27540	Aryl hydrocarbon receptor nuclear translocator	Unclassified protein	C00008866	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00008866	1 / 1
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002647	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00029724	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00002647	0 / 1
P10145	Interleukin-8	Secreted protein	C00002647	0 / 0
O75496	Geminin	Unclassified protein	C00001110	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002647	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00008866	0 / 0
P16581	E-selectin	Adhesion	C00002647	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00029724	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00008866	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00008866	0 / 0
P78536	Disintegrin and metalloproteinase domain-containing protein 17	M12B	C00002647	1 / 0
P08183	Multidrug resistance protein 1	drug	C00003672	1 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00030754	1 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001062	2 / 1

128 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000947 C00002647
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000947 C00002647
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000947 C00002647
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000947 C00002647
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00000947 C00002647
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00000947 C00002647
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000947 C00002647
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000947 C00002647
581	BAX, BCL2L4	BCL2-associated X protein	C00000947 C00002647
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000947 C00002647
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000947 C00002647
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00000947 C00002647
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00000947 C00002647
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000947 C00002647
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000947 C00002647
898	CCNE1, CCNE	cyclin E1	C00002647
694	BTG1	B-cell translocation gene 1, anti-proliferative	C00000947
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000947
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00000947
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000947
930	CD19, B4, CVID3	CD19 molecule	C00000947
975	CD81, CVID6, S5.7, TAPA1, TSPAN28	CD81 molecule	C00000947
928	CD9, BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29	CD9 molecule	C00000947
1054	CEBPG, GPE1BP, IG/EBP-1	CCAAT/enhancer binding protein (C/EBP), gamma	C00000947
10978	CLP1, HEAB, hClp1	cleavage and polyadenylation factor I subunit 1 (EC:2.7.1.78)	C00000947
10063	COX17	COX17 cytochrome c oxidase copper chaperone	C00000947
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00000947
79184	BRCC3, BRCC36, C6.1A, CXorf53	BRCA1/BRCA2-containing complex, subunit 3 (EC:3.1.2.15)	C00000947
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000947
7913	DEK, D6S231E	DEK oncogene	C00000947
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00000947
2130	EWSR1, EWS, bK984G1.4	EWS RNA-binding protein 1	C00000947
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00000947
2323	FLT3LG, FL, FLT3L	fms-related tyrosine kinase 3 ligand	C00000947
2495	FTH1, FHC, FTH, FTHL6, PIG15, PLIF	ferritin, heavy polypeptide 1 (EC:1.16.3.1)	C00000947
2896	GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN	granulin	C00000947
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00000947
3054	HCFC1, CFF, HCF-1, HCF1, HFC1, MRX3, VCAF	host cell factor C1 (VP16-accessory protein)	C00000947
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000947
3232	HOXD3, HOX1D, HOX4, HOX4A, Hox-4.1	homeobox D3	C00000947
3329	HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13	heat shock 60kDa protein 1 (chaperonin)	C00000947
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000947
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00000947
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000947
3559	IL2RA, CD25, IDDM10, IL2R, TCGFR	interleukin 2 receptor, alpha	C00000947
9235	IL32, IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd	interleukin 32	C00000947
3662	IRF4, LSIRF, MUM1, NF-EM5	interferon regulatory factor 4	C00000947
3683	ITGAL, CD11A, LFA-1, LFA1A	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	C00000947
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00000947
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00000947
388962	BOLA3, MMDS2	bolA family member 3	C00000947
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00000947
637	BID, FP497	BH3 interacting domain death agonist	C00000947
56751	BARHL1	BarH-like homeobox 1	C00000947
4282	MIF, GIF, GLIF, MMIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)	C00000947
64975	MRPL41, BMRP, MRP-L27, MRPL27, RPML27	mitochondrial ribosomal protein L41	C00000947
4493	MT1E, MT1, MTD	metallothionein 1E	C00000947
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00000947
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000947
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00000947
4851	NOTCH1, TAN1, hN1	notch 1	C00000947
4869	NPM1, B23, NPM	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	C00000947
5175	PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM	platelet/endothelial cell adhesion molecule 1	C00000947
5187	PER1, PER, RIGUI, hPER	period circadian clock 1	C00000947
5327	PLAT, T-PA, TPA	plasminogen activator, tissue (EC:3.4.21.68)	C00000947
5328	PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA	plasminogen activator, urokinase (EC:3.4.21.73)	C00000947
7916	PRRC2A, BAT2, D6S51, D6S51E, G2	proline-rich coiled-coil 2A	C00000947
2683	B4GALT1, B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38)	C00000947
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00000947
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00000947
5915	RARB, HAP, NR1B2, RRB2	retinoic acid receptor, beta	C00000947
393	ARHGAP4, C1, RGC1, RhoGAP4, SrGAP4, p115	Rho GTPase activating protein 4	C00000947
6128	RPL6, L6, SHUJUN-2, TAXREB107, TXREB1	ribosomal protein L6	C00000947
6285	S100B, NEF, S100, S100-B, S100beta	S100 calcium binding protein B	C00000947
6286	S100P, MIG9	S100 calcium binding protein P	C00000947
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00000947
7536	SF1, BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162	splicing factor 1	C00000947
6574	SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1	solute carrier family 20 (phosphate transporter), member 1	C00000947
6699	SPRR1B, CORNIFIN, GADD33, SPRR1	small proline-rich protein 1B	C00000947
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000947
6777	STAT5B, STAT5	signal transducer and activator of transcription 5B	C00000947
6778	STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C	signal transducer and activator of transcription 6, interleukin-4 induced	C00000947
302	ANXA2, ANX2, ANX2L4, CAL1H, LIP2, LPC2, LPC2D, P36, PAP-IV	annexin A2	C00000947
6932	TCF7, TCF-1	transcription factor 7 (T-cell specific, HMG-box)	C00000947
7083	TK1, TK2	thymidine kinase 1, soluble (EC:2.7.1.21)	C00000947
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00000947
943	TNFRSF8, CD30, D1S166E, Ki-1	tumor necrosis factor receptor superfamily, member 8	C00000947
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00000947
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00000947
2829	XCR1, CCXCR1, GPR5	chemokine (C motif) receptor 1	C00000947
51042	ZNF593, ZT86	zinc finger protein 593	C00000947
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002647
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00002647
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00002647
545	ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1	ataxia telangiectasia and Rad3 related (EC:2.7.11.1)	C00002647
613	BCR, ALL, BCR1, CML, D22S11, D22S662, PHL	breakpoint cluster region (EC:2.7.11.1)	C00002647
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00000947
998	CDC42, CDC42Hs, G25K	cell division cycle 42	C00002647
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002647
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002647
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002647
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002647
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002647
2551	GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07	GA binding protein transcription factor, alpha subunit 60kDa	C00002647
2885	GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2	growth factor receptor-bound protein 2	C00002647
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00002647
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002647
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002647
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002647
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002647
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002647
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00002647
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002647
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00002647
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002647
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00002647
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00002647
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002647
19412			C00002647
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00002647
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00002647
6195	RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)	C00002647
9252	RPS6KA5, MSK1, MSPK1, RLPK	ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1)	C00002647
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00002647
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002647
7224	TRPC5, TRP5	transient receptor potential cation channel, subfamily C, member 5	C00002647
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00002647
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002647

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