PCIDB

Semecarpus vitiensis

Species

KNApSAcK Entry

Organism name Semecarpus vitiensis
Genus Semecarpus
Family Anacardiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Semecarpus
Linked NCBI taxonomy ID 173682
Linked level genus

Family

Family in NCBI taxonomy Anacardiaceae
ID 4011

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00005290 External link 512 Mumenin
No. 2 No. 15
C00005732 External link 512 Myricetin 7-glucoside
No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00001060 External link 512 Kaempferide
CHEMBL40919
6 / 7 / 4 No. 3 No. 15
C00001071 External link 512 Myricetin
CHEMBL164
C040015
78 / 70 / 56 39 / 2 No. 3 No. 15
C00008724 External link 512 Ampelopsin 3'-glucoside
No. 12 No. 14
C00004565 External link 512 Kaempferol
/ Nimbecetin
/ Rhamnolutein
/ Pelargidenolon
/ 5,7,4'-Trihydroxyflavonol
/ 3,5,7,4'-Tetrahydroxyflavone
/ 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL150
C006552
76 / 69 / 87 86 / 8 No. 71 No. 15
C00006924 External link 512 3,4,2'-Trihydroxychalcone
CHEMBL339587
25 / 18 / 47 No. 92 No. 13
C00002647 External link 512 Gallic acid
CHEMBL288114
D005707
42 / 53 / 68 52 / 16 No. 817 No. 81
C00002644 External link 512 Catechol
/ Pyrocatechol
CHEMBL280998
C034221
148 / 82 / 64 22 / 5 No. 1590 No. 82

Human Protein / Gene in interactions

233 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001071 C00002644 C00002647 C00004565 C00005374 C00006924 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001071 C00002644 C00004565 C00005374 C00006924 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001071 C00002644 C00002647 C00005374 C00006924 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001071 C00002644 C00004565 C00005374 C00006924 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001071 C00002644 C00004565 C00005374 C00006924 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001071 C00002644 C00002647 C00004565 C00006924 0 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00001071 C00002644 C00002647 C00004565 C00006924 4 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001071 C00002644 C00002647 C00004565 C00005374 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001071 C00002644 C00002647 C00004565 C00005374 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001071 C00002644 C00004565 C00005374 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001071 C00002644 C00002647 C00006924 0 / 0
P15121 Aldose reductase Enzyme C00001071 C00002647 C00004565 C00005374 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001071 C00002644 C00002647 C00004565 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002644 C00002647 C00004565 C00006924 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001071 C00002644 C00004565 C00005374 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001071 C00002644 C00002647 C00004565 2 / 2
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001071 C00002644 C00002647 C00004565 3 / 3
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001060 C00001071 C00002644 C00004565 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001071 C00002644 C00004565 C00006924 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001071 C00002644 C00002647 C00005374 0 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001060 C00001071 C00004565 4 / 4
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001071 C00002644 C00004565 0 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00002644 C00002647 C00006924 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001060 C00001071 C00004565 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002644 C00002647 C00004565 0 / 1
P02545 Prelamin-A/C Unclassified protein C00002644 C00002647 C00004565 11 / 10
P83916 Chromobox protein homolog 1 Unclassified protein C00001071 C00002644 C00006924 0 / 0
P03372 Estrogen receptor NR3A1 C00002644 C00002647 C00004565 1 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001071 C00004565 C00006924 1 / 2
P22303 Acetylcholinesterase Hydrolase C00001071 C00002644 C00004565 1 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001071 C00002644 C00005374 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002644 C00004565 C00006924 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002647 C00004565 C00006924 7 / 37
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001071 C00002644 C00004565 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001071 C00002644 C00004565 0 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001071 C00002644 C00004565 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001071 C00002644 C00004565 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00001071 C00002644 C00004565 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001071 C00002644 C00004565 1 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001071 C00002644 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00001060 C00001071 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00002644 C00002647 1 / 2
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001071 C00002644 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002644 C00002647 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00002644 C00004565 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00001071 C00002644 5 / 2
P43166 Carbonic anhydrase 7 Lyase C00002644 C00002647 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001060 C00004565 2 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002644 C00002647 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002644 C00002647 0 / 1
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002644 C00002647 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00001071 C00004565 0 / 0
Q04760 Lactoylglutathione lyase Enzyme C00001071 C00004565 0 / 0
P08183 Multidrug resistance protein 1 drug C00001060 C00004565 1 / 0
P04062 Glucosylceramidase Enzyme C00001071 C00004565 6 / 4
Q96RI1 Bile acid receptor NR1H4 C00002644 C00004565 0 / 0
P04745 Alpha-amylase 1 Enzyme C00001071 C00004565 0 / 0
P06276 Cholinesterase Hydrolase C00001071 C00004565 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00002644 C00002647 1 / 1
P06746 DNA polymerase beta Enzyme C00001071 C00002644 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00002644 C00004565 5 / 3
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001071 C00002644 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001071 C00004565 0 / 0
P54132 Bloom syndrome protein Enzyme C00001071 C00002644 1 / 2
P40225 Thrombopoietin Unclassified protein C00001071 C00002644 1 / 1
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00001071 C00002644 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002644 C00004565 2 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00002644 C00004565 1 / 8
P21728 D(1A) dopamine receptor Dopamine receptor C00001071 C00002644 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00001071 C00004565 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00001071 C00002647 2 / 3
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002644 C00004565 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001071 C00002644 2 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001071 C00006924 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002644 C00002647 0 / 0
P10145 Interleukin-8 Secreted protein C00002644 C00002647 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00002644 C00002647 4 / 1
P23280 Carbonic anhydrase 6 Lyase C00002644 C00002647 0 / 0
O75496 Geminin Unclassified protein C00002644 C00006924 0 / 0
O00255 Menin Unclassified protein C00001071 C00004565 2 / 5
Q9Y3R4 Sialidase-2 Enzyme C00001071 C00004565 0 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00001071 C00004565 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00001071 C00002644 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00001071 C00004565 1 / 1
O43570 Carbonic anhydrase 12 Lyase C00002644 C00002647 1 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase C00002644 C00002647 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00002644 C00006924 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00002644 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00002644 1 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00002644 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002644 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00002644 1 / 1
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00002644 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002647 0 / 0
Q15746 Myosin light chain kinase, smooth muscle Mlck C00001071 1 / 1
P51151 Ras-related protein Rab-9A Unclassified protein C00002644 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00002644 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00002644 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00002644 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00002644 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00002644 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00002644 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002644 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00002644 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00002644 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00002644 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00002644 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00002644 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00002644 1 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00002644 0 / 0
Q14790 Caspase-8 C14 C00001071 2 / 1
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00002644 0 / 0
P08311 Cathepsin G S1A C00002644 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00004565 0 / 1
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002644 1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00006924 0 / 0
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x C00004565 1 / 1
P03956 Interstitial collagenase M10A C00002644 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00002644 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00002644 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00001071 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00001071 3 / 1
P14416 D(2) dopamine receptor Dopamine receptor C00002644 2 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00006924 1 / 2
P11387 DNA topoisomerase 1 Isomerase C00001071 0 / 0
Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Enzyme C00004565 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001071 1 / 0
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00001071 0 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00002644 1 / 1
P07237 Protein disulfide-isomerase Enzyme C00005374 0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00001071 5 / 4
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00002644 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00002644 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00001071 2 / 2
P14679 Tyrosinase Oxidoreductase C00004565 4 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002644 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00002644 2 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00004565 0 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00002644 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00002644 1 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00004565 0 / 0
P21452 Substance-K receptor Neurokinin receptor C00002644 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00002644 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00002644 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00002644 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00002644 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00002644 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001071 2 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00002644 0 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00002647 2 / 3
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00002644 1 / 0
P78536 Disintegrin and metalloproteinase domain-containing protein 17 M12B C00002647 1 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00001071 0 / 1
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00002644 2 / 1
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00004565 1 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00002644 0 / 0
P08253 72 kDa type IV collagenase M10A C00002644 1 / 3
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00002644 0 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00002644 0 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001071 1 / 1
Q01959 Sodium-dependent dopamine transporter Dopamine C00002644 1 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00002644 1 / 1
P35367 Histamine H1 receptor Histamine receptor C00002644 0 / 0
P25021 Histamine H2 receptor Histamine receptor C00002644 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00006924 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00002644 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002644 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00002644 1 / 0
P12821 Angiotensin-converting enzyme M2 C00002647 4 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00002644 0 / 1
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00002644 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00002644 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00002644 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00002644 0 / 0
P16581 E-selectin Adhesion C00002647 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00002644 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00002644 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00002644 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00004565 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00001071 0 / 0
P14151 L-selectin Adhesion C00002647 0 / 0
P16109 P-selectin Adhesion C00002647 1 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme C00001071 0 / 1
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00004565 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002644 2 / 2
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00002644 0 / 0
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00004565 1 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00004565 0 / 0
Q15046 Lysine--tRNA ligase Enzyme C00001071 2 / 1
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00006924 1 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00002647 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00002644 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00002647 5 / 1
P17252 Protein kinase C alpha type Alpha C00002644 0 / 0
P29466 Caspase-1 C14 C00002644 0 / 0
P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Enzyme C00001071 9 / 1
P10275 Androgen receptor NR3C4 C00004565 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00002644 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00002644 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00002644 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00004565 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00002644 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00002644 1 / 1
P22894 Neutrophil collagenase M10A C00002644 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00002644 0 / 1
P10253 Lysosomal alpha-glucosidase Hydrolase C00006924 1 / 1
P35869 Aryl hydrocarbon receptor Transcription Factor C00004565 0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00002644 0 / 0
P08254 Stromelysin-1 M10A C00002644 1 / 0
P48147 Prolyl endopeptidase S9A C00004565 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00002644 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00002644 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002647 3 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00002644 0 / 0
P08246 Neutrophil elastase S1A C00002644 2 / 1
P31941 DNA dC->dU-editing enzyme APOBEC-3A Enzyme C00001071 0 / 0
Q9NPH5 NADPH oxidase 4 Enzyme C00004565 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002644 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00006924 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001071 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001071 1 / 4
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00004565 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00004565 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00004565 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00004565 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00004565 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00004565 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00004565 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00004565 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001071 2 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00006924 1 / 1
Q9HCT0 Fibroblast growth factor 22 Unclassified protein C00001071 0 / 0

152 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001071 C00002644 C00002647 C00004565
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001071 C00004565 C00005374
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00001071 C00002647 C00004565
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001071 C00004565 C00005374
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00001071 C00002647 C00004565
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00001071 C00002647 C00004565
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00001071 C00002647 C00004565
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00001071 C00002647 C00004565
581 BAX, BCL2L4 BCL2-associated X protein C00001071 C00002647 C00004565
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001071 C00002647 C00004565
1147 CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) C00002647 C00004565
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00001071 C00002644
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00001071 C00004565
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00002644 C00004565
891 CCNB1, CCNB cyclin B1 C00001071 C00004565
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00001071 C00002644
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00002647 C00004565
1031 CDKN2C, INK4C, p18, p18-INK4C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) C00001071 C00004565
7161 TP73, P73 tumor protein p73 C00001071 C00004565
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002644 C00002647
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00001071 C00004565
9540 TP53I3, PIG3 tumor protein p53 inducible protein 3 C00001071 C00004565
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00002647 C00004565
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 ataxia telangiectasia mutated (EC:2.7.11.1) C00002647 C00004565
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00002644 C00002647
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00001071 C00002647
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002647 C00004565
6513 SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED solute carrier family 2 (facilitated glucose transporter), member 1 C00001071 C00004565
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001071 C00002647
8000 PSCA, PRO232 prostate stem cell antigen C00001071 C00004565
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00001071 C00004565
4233 MET, AUTS9, HGFR, RCCP2, c-Met met proto-oncogene (EC:2.7.10.1) C00001071 C00004565
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00001071 C00004565
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002647 C00004565
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002647 C00004565
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001071 C00004565
3082 HGF, DFNB39, F-TCF, HGFB, HPTA, SF hepatocyte growth factor (hepapoietin A; scatter factor) C00001071 C00004565
3043 HBB, CD113t-C, beta-globin hemoglobin, beta C00002644 C00004565
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00001071
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00004565
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00004565
9687 GREB1 growth regulation by estrogen in breast cancer 1 C00004565
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00004565
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00004565
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00004565
3567 IL5, EDF, IL-5, TRF interleukin 5 (colony-stimulating factor, eosinophil) C00004565
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00004565
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00004565
4297 KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) C00004565
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00004565
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00004565
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00004565
110357 C00004565
4502 MT2A, MT2 metallothionein 2A C00004565
4586 MUC5AC, MUC5, TBM, leB mucin 5AC, oligomeric mucus/gel-forming C00004565
8202 NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP nuclear receptor coactivator 3 (EC:2.3.1.48) C00004565
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00004565
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00004565
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00004565
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00004565
9970 NR1I3, CAR, CAR1, MB67 nuclear receptor subfamily 1, group I, member 3 C00004565
5241 PGR, NR3C3, PR progesterone receptor C00004565
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00004565
1734 DIO2, 5DII, D2, DIOII, SelY, TXDI2 deiodinase, iodothyronine, type II (EC:1.97.1.10) C00004565
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00004565
6119 RPA3, REPA3 replication protein A3, 14kDa C00004565
2810 SFN, YWHAS stratifin C00004565
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00004565
6773 STAT2, ISGF-3, P113, STAT113 signal transducer and activator of transcription 2, 113kDa C00004565
7019 TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 transcription factor A, mitochondrial C00004565
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00004565
7039 TGFA, TFGA transforming growth factor, alpha C00004565
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00004565
37618 C00004565
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00004565
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00004565
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00004565
7352 UCP3, SLC25A9 uncoupling protein 3 (mitochondrial, proton carrier) C00004565
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00004565
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00004565
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00004565
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00004565
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00004565
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00004565
7402 UTRN, DMDL, DRP, DRP1 utrophin C00004565
8839 WISP2, CCN5, CT58, CTGF-L WNT1 inducible signaling pathway protein 2 C00004565
212 ALAS2, ALAS-E, ALASE, ANH1, ASB, XLDPP, XLEPP, XLSA aminolevulinate, delta-, synthase 2 (EC:2.3.1.37) C00002644
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00002644
6356 CCL11, SCYA11 chemokine (C-C motif) ligand 11 C00002644
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00002644
6348 CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 chemokine (C-C motif) ligand 3 C00002644
6351 CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 chemokine (C-C motif) ligand 4 C00002644
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00004565
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00002644
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00002644
3145 HMBS, PBG-D, PBGD, PORC, UPS hydroxymethylbilane synthase (EC:2.5.1.61) C00002644
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00002644
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00004565
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00004565
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00002644
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00004565
6799 SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) C00002644
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00002644
6819 SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2 sulfotransferase family, cytosolic, 1C, member 2 (EC:2.8.2.-) C00002644
7037 TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 transferrin receptor C00002644
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00001071
397 ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 Rho GDP dissociation inhibitor (GDI) beta C00001071
847 CAT catalase (EC:1.11.1.6) C00001071
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00001071
1786 DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) C00001071
54583 EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29) C00001071
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001071
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001071
239 ALOX12, 12-LOX, 12S-LOX, LOG12 arachidonate 12-lipoxygenase (EC:1.13.11.31) C00004565
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00004565
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001071
196 AHR, bHLHe76 aryl hydrocarbon receptor C00004565
23411 SIRT1, SIR2L1 sirtuin 1 C00001071
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00001071
25 ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) C00002647
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00002647
545 ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 ataxia telangiectasia and Rad3 related (EC:2.7.11.1) C00002647
613 BCR, ALL, BCR1, CML, D22S11, D22S662, PHL breakpoint cluster region (EC:2.7.11.1) C00002647
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002647
898 CCNE1, CCNE cyclin E1 C00002647
998 CDC42, CDC42Hs, G25K cell division cycle 42 C00002647
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00002647
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00002647
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002647
2551 GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07 GA binding protein transcription factor, alpha subunit 60kDa C00002647
2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 growth factor receptor-bound protein 2 C00002647
3551 IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) C00002647
3949 LDLR, FH, FHC, LDLCQ2 low density lipoprotein receptor C00002647
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00002647
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00002647
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00002647
4255 MGMT O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) C00002647
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002647
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) C00002647
4793 NFKBIB, IKBB, TRIP9 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta C00002647
5578 PRKCA, AAG6, PKC-alpha, PKCA, PRKACA protein kinase C, alpha (EC:2.7.11.13) C00002647
5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) C00002647
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00002647
19412 C00002647
387 RHOA, ARH12, ARHA, RHO12, RHOH12 ras homolog family member A C00002647
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00002647
6195 RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) C00002647
9252 RPS6KA5, MSK1, MSPK1, RLPK ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1) C00002647
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00002647
7224 TRPC5, TRP5 transient receptor potential cation channel, subfamily C, member 5 C00002647
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00002647
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00002647

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (161)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#600807 Asthma, susceptibility to Q13093
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#114480 Breast cancer P42336
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#607271 Caspase 8 deficiency Q14790
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#114500 Colorectal cancer; crc P18054
P42336
Q14191
#612918 Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi P42336
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#615108 Cowden syndrome 5; cws5 P42336
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#162800 Cyclic neutropenia P08246
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#612219 Ewing sarcoma; es P11308
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#232300 Glycogen storage disease ii P10253
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#114550 Hepatocellular carcinoma P08581
P42336
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#147050 Ige responsiveness, atopic; iger Q13093
#612244 Inflammatory bowel disease 13; ibd13 P08183
#614328 Inflammatory skin and bowel disease, neonatal; nisbd P78536
#603932 Intervertebral disc disease; idd P14780
#182000 Keratosis, seborrheic P42336
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
Q14790
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#602501 Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap P42336
#603387 Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph P42336
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P42336
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#267430 Renal tubular dysgenesis; rtd P12821
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P12821
P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (125)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P42336 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P08581 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
P28907 (marker)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P27487 (marker)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00213 Hypophosphatasia P05186 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
P11308 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00035 Ewing's sarcoma P11308 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00409 Type II diabetes mellitus P37231 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00107 Other well-defined immunodeficiency syndromes P98170 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00108 Autoimmune lymphoproliferative syndromes (ALPS) Q14790 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) Q15746 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

30 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009203 Myocardial Infarction C00001071
C00002647
D006943 Hyperglycemia C00004565
C00002647
D050197 Atherosclerosis C00004565
D002318 Cardiovascular Diseases C00004565
D001943 Breast Neoplasms C00004565
D007938 Leukemia C00004565
D010024 Osteoporosis C00004565
D011297 Prenatal Exposure Delayed Effects C00004565
D010146 Pain C00005374
D002869 Chromosome Aberrations C00002644
D048629 Micronuclei, Chromosome-Defective C00002644
D009784 Occupational Diseases C00002644
D011041 Poisoning C00002644
D012640 Seizures C00002644
D005909 Glioblastoma C00001071
D009202 Cardiomyopathies C00004565
D003921 Diabetes Mellitus, Experimental C00002647
D050171 Dyslipidemias C00002647
D005234 Fatty Liver C00002647
D018149 Glucose Intolerance C00002647
D006937 Hypercholesterolemia C00002647
D006949 Hyperlipidemias C00002647
D015228 Hypertriglyceridemia C00002647
D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive C00002647
D008546 Melanoma, Experimental C00002647
D009069 Movement Disorders C00002647
D009361 Neoplasm Invasiveness C00002647
D009362 Neoplasm Metastasis C00002647
D012516 Osteosarcoma C00002647
D010182 Pancreatic Diseases C00002647