Species

KNApSAcK Entry

Organism name Juniperus macropoda
Genus Juniperus
Family Cupressaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Juniperus
Linked NCBI taxonomy ID 13100
Linked level genus

Family

Family in NCBI taxonomy Cupressaceae
ID 3367

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00010148 External link 512 Iristectorigenin A 7-O-gentiobioside
No. 1 No. 15
C00005138 External link 512 Astragalin
/ Kaempferol 3-glucoside
/ Kaempferol 3-O-beta-D-glucoside
/ Kaempferol 3-O-beta-D-glucopyranoside
CHEMBL233930
CHEMBL453290
CHEMBL1572115
C001579
10 / 6 / 7 0 / 1 No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00005632 External link 512 Quercetagetin 3-rhamnoside
No. 2 No. 15
C00010137 External link 512 Iridin
/ Irigenin 7-O-glucoside
CHEMBL487014
CHEMBL1475472
No. 2 No. 15
C00010149 External link 512 Junipegenin B 7-O-glucoside
No. 2 No. 15
C00010151 External link 512 5,7,4'-Trihydroxy-6,3',5'-trimethoxyisoflavone 7-O-glucoside
No. 2 No. 15
C00009488 External link 512 Junipegenin C
/ 5,7-Dihydroxy-6,3',4',5'-tetramethoxyisoflavone
No. 3 No. 15
C00009465 External link 512 Junipegenin A
/ 5,7,3',5'-Tetrahydroxy-4'-methoxyisoflavone
No. 3 No. 15
C00009480 External link 512 Dalspinosin
/ Junipegenin B
/ 5,7-Dihydroxy-6,3',4'-trimethoxyisoflavone
No. 3 No. 15
C00009485 External link 512 Irigenin
/ 5,7,3'-Trimethoxy-6,4',5'-trimethoxyisoflavone
CHEMBL487013
No. 3 No. 15
C00001049 External link 512 Hinokiflavone
CHEMBL291426
C060299
2 / 1 / 2 No. 34 No. 18

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P07237 Protein disulfide-isomerase Enzyme C00005138 C00005374 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005138 C00005374 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005138 C00005374 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005138 C00005374 1 / 1
P15121 Aldose reductase Enzyme C00005138 C00005374 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00005374 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005374 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005374 1 / 1
P43235 Cathepsin K C1A C00001049 1 / 2
P14679 Tyrosinase Oxidoreductase C00005138 4 / 2
P56817 Beta-secretase 1 A1A C00001049 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005138 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005138 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00005374 0 / 0
Q99700 Ataxin-2 Unclassified protein C00005138 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00005374 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005374 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005374 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00005138 0 / 3

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005374

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#265800 Pycnodysostosis P43235
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (10)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00273 Pycnodysostosis P43235 (related)
H00425 Lysosomal cysteine protease deficiencies P43235 (related)
H00192 Xanthinuria P47989 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003876 Dermatitis, Atopic C00005138
D010146 Pain C00005374