PCIDB

KNApSAcK Metabolite C00005138

Metabolite

KNApSAcK Entry

id C00005138
Name Astragalin / Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside
CAS RN 480-10-4
Standard InChI InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2/t13-,15-,17?,18?,21+/m1/s1
Standard InChI (Main Layer) InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 2

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL233930 CHEMBL453290 CHEMBL1572115

KEGG

By LinkDB C12249

CTD

By CAS RN C001579

Species

Summary

Plant class

class name count
rosids 43
asterids 34
Magnoliophyta 10
Spermatophyta 5
Liliopsida 5
Euphyllophyta 4
eudicotyledons 4

Family (Top 10)

family name count
Fabaceae 19
Asteraceae 11
Annonaceae 8
Lamiaceae 5
Euphorbiaceae 5
Apiaceae 3
Iridaceae 3
Urticaceae 2
Hypericaceae 2
Podocarpaceae 2

List (105)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Abies amabilis 97174 Pinaceae Spermatophyta Viridiplantae
Agrimonia eupatoria 57912 Rosaceae rosids Viridiplantae
Alkanna orientalis 543563 Boraginaceae asterids Viridiplantae
Allium porrum L. 4678 Amaryllidaceae Liliopsida Viridiplantae
Ammi majus L. 48026 Apiaceae asterids Viridiplantae
Angelica furcijuga KITAGAWA 40948 Apiaceae asterids Viridiplantae
Annona crassiflora 508206 Annonaceae Magnoliophyta Viridiplantae
Arnica montana cv.ARBO 4246 Asteraceae asterids Viridiplantae
Ascarina lucida 130721 Chloranthaceae Magnoliophyta Viridiplantae
Astragalus dipelta 144095 Fabaceae rosids Viridiplantae
Astragalus spp. 20400 Fabaceae rosids Viridiplantae
Baptisia spp. 49796 Fabaceae rosids Viridiplantae
Bauhinia variegata L. 167791 Fabaceae rosids Viridiplantae
Belamcanda chinensis 58944 Iridaceae Liliopsida Viridiplantae
Bocagea sp.nov. 22140 Annonaceae Magnoliophyta Viridiplantae
Boehmeria holosericea 83905 Urticaceae rosids Viridiplantae
Boehmeria tricuspis 644073 Urticaceae rosids Viridiplantae
Camellia sinensis 4442 Theaceae asterids Viridiplantae
Cardiopetalum calophyllum 22140 Annonaceae Magnoliophyta Viridiplantae
Carthamus tinctorius 4222 Asteraceae asterids Viridiplantae
Carum carvi 48032 Apiaceae asterids Viridiplantae
Clibadium spp. 183010 Asteraceae asterids Viridiplantae
Clitoria ternata 43365 Fabaceae rosids Viridiplantae
Clitoria ternatea 43366 Fabaceae rosids Viridiplantae
Conyza filaginoides 41552 Asteraceae asterids Viridiplantae
Cornus kousa 28501 Cornaceae asterids Viridiplantae
Crocus antalyensis 481018 Iridaceae Liliopsida Viridiplantae
Crocus sativus 82528 Iridaceae Liliopsida Viridiplantae
Curcuma mangga 379528 Zingiberaceae Liliopsida Viridiplantae
Diospyros kaki 35925 Ebenaceae asterids Viridiplantae
Duguetia chrysocarpa 294142 Annonaceae Magnoliophyta Viridiplantae
Euphorbia chamaesyce 1046441 Euphorbiaceae rosids Viridiplantae
Euphorbia larica 1031526 Euphorbiaceae rosids Viridiplantae
Euphorbia magalanta 3977 Euphorbiaceae rosids Viridiplantae
Euphorbia virgata 526204 Euphorbiaceae rosids Viridiplantae
Evolvulus alsinoides 439689 Convolvulaceae asterids Viridiplantae
Fraxinus oxycarba 38871 Oleaceae asterids Viridiplantae
Gerbera jamesonii 13547 Asteraceae asterids Viridiplantae
Gossypium barbadense 3634 Malvaceae rosids Viridiplantae
Guatteria rupestris 295187 Annonaceae Magnoliophyta Viridiplantae
Guatteria villosissima 295194 Annonaceae Magnoliophyta Viridiplantae
Gutierrezia wrightii 71047 Asteraceae asterids Viridiplantae
Haplopappus foliosus 147773 Asteraceae asterids Viridiplantae
Haplophyllum glabrinum 266078 Rutaceae rosids Viridiplantae
Hebe parviflora 163752 Plantaginaceae asterids Viridiplantae
Helichrysum graveolen 59430 Asteraceae asterids Viridiplantae
Helicteres angustifolia 190244 Malvaceae rosids Viridiplantae
Hirschfeldia incana 71354 Brassicaceae rosids Viridiplantae
Hypericum erectum Thunb. 282539 Hypericaceae rosids Viridiplantae
Hypericum sampsonii 282553 Hypericaceae rosids Viridiplantae
Juniperus macropoda 13100 Cupressaceae Spermatophyta Viridiplantae
Larix decidua 71402 Pinaceae Spermatophyta Viridiplantae
Leonurus persicus 4137 Lamiaceae asterids Viridiplantae
Leptarrhena pyrolifolia 23253 Saxifragaceae eudicotyledons Viridiplantae
Liquidambar formosana 63359 Altingiaceae eudicotyledons Viridiplantae
Lotus corniculatus 47247 Fabaceae rosids Viridiplantae
Lotus japonicus 34305 Fabaceae rosids Viridiplantae
Lupinus albus L. 3870 Fabaceae rosids Viridiplantae
Marah oreganus 252534 Cucurbitaceae rosids Viridiplantae
Morus alba L. 3498 Moraceae rosids Viridiplantae
Morus insignis 1031565 Moraceae rosids Viridiplantae
Nyctanthes arbortristis 41398 Oleaceae asterids Viridiplantae
Nymphaea caerulea 49506 Nymphaeaceae Magnoliophyta Viridiplantae
Ochna beddomei 56628 Ochnaceae rosids Viridiplantae
Ochna obtusata 56628 Ochnaceae rosids Viridiplantae
Onobrychis amoena 1233737 Fabaceae rosids Viridiplantae
Onobrychis bobrovi 3881 Fabaceae rosids Viridiplantae
Onobrychis chlorassanica 3881 Fabaceae rosids Viridiplantae
Onobrychis echidna 3881 Fabaceae rosids Viridiplantae
Onobrychis ferganica 3881 Fabaceae rosids Viridiplantae
Onobrychis grandis 3881 Fabaceae rosids Viridiplantae
Onobrychis seravschanica 3881 Fabaceae rosids Viridiplantae
Ononis leiosperma 58889 Fabaceae rosids Viridiplantae
Pelargonium reniforme 59871 Geraniaceae rosids Viridiplantae
Phegopteris connectilis 173899 Thelypteridaceae Euphyllophyta Viridiplantae
Phellodendron amurense 68554 Rutaceae rosids Viridiplantae
Phlomis caucasica 316257 Lamiaceae asterids Viridiplantae
Phlomis spectabilis 316257 Lamiaceae asterids Viridiplantae
Phlomis spinidens 316257 Lamiaceae asterids Viridiplantae
Phyllanthus niruri 296034 Phyllanthaceae rosids Viridiplantae
Podocarpus fasciculus 120615 Podocarpaceae Spermatophyta Viridiplantae
Podocarpus nivalis 120625 Podocarpaceae Spermatophyta Viridiplantae
Pteridium aquilinum 32101 Dennstaedtiaceae Euphyllophyta Viridiplantae
Pulsatilla cernua 231674 Ranunculaceae eudicotyledons Viridiplantae
Pyrola spp. 13650 Ericaceae asterids Viridiplantae
Rollinia dolabripetala 301698 Annonaceae Magnoliophyta Viridiplantae
Saintpaulia ionatha 48792 Gesneriaceae asterids Viridiplantae
Salvia cavaleriei 424418 Lamiaceae asterids Viridiplantae
Sapium haematospermum 316852 Euphorbiaceae rosids Viridiplantae
Silphium perfoliatum L. 53588 Asteraceae asterids Viridiplantae
Sinocrassula indica 91157 Crassulaceae eudicotyledons Viridiplantae
Solanum elaeagnifolium 115664 Solanaceae asterids Viridiplantae
Solenostemma argel 219273 Apocynaceae asterids Viridiplantae
Solidago altissima 59294 Asteraceae asterids Viridiplantae
Sophora japonica 3897 Fabaceae rosids Viridiplantae
Spermacoce laevis Roxb. 35916 Rubiaceae asterids Viridiplantae
Spiraea formosana 409510 Rosaceae rosids Viridiplantae
Stenochlaena palustris 32079 Blechnaceae Euphyllophyta Viridiplantae
Strychnos spinosa 99302 Loganiaceae asterids Viridiplantae
Tephrosia calophylla 998011 Fabaceae rosids Viridiplantae
Tetrapanax papyriferus 46417 Araliaceae asterids Viridiplantae
Thelypteris nipponica 746521 Thelypteridaceae Euphyllophyta Viridiplantae
Tribulus alatus Del. 43873 Zygophyllaceae rosids Viridiplantae
Xylopia aromatica 225838 Annonaceae Magnoliophyta Viridiplantae
Zinnia elegans 34245 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1572115 CHEMBL2114784 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1572115 CHEMBL1794585 (1)
0 / 0
P07237 Protein disulfide-isomerase Enzyme CHEMBL233930 CHEMBL1572115 CHEMBL1964080 (2) CHEMBL2114805 (2)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL233930 CHEMBL1942674 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1572115 CHEMBL1794569 (1)
1 / 1
P14679 Tyrosinase Oxidoreductase CHEMBL233930 CHEMBL814345 (1)
4 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL233930 CHEMBL1738588 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL233930 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL233930 CHEMBL1614211 (1)
0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein CHEMBL233930 CHEMBL2114913 (1)
0 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (7)

KEGG disease name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D003876 C001579 Dermatitis, Atopic therapeutic
22210036