Hypericum erectum Thunb.
Species
KNApSAcK Entry
| Organism name | Hypericum erectum Thunb. |
|---|---|
| Genus | Hypericum |
| Family | Hypericaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Hypericum erectum |
|---|---|
| Linked NCBI taxonomy ID | 282539 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Hypericaceae |
|---|---|
| ID | 629714 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (16)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004273
|
Dracocephaloside
/ Luteolin 3'-glucoside / Luteolin 3'-O-beta-glucoside / Luteolin 3'-beta-D-glucopyranoside |
CHEMBL1221790
|
No. 2 | No. 15 |
|
|||
|
C00004276
|
Juncein
/ Luteolin 4'-glucoside / Luteolin 4'-O-beta-D-glucopyranoside / 5,7,3',4'-Tetrahydroxyflavone 4'-beta-D-glucopyranoside |
CHEMBL459822
|
No. 2 | No. 15 |
|
|||
|
C00005137
|
Trifolin
/ Kaempferol 3-O-beta-D-galactopyranoside |
CHEMBL233930
CHEMBL453290 CHEMBL1572115 |
C066407
|
10 / 6 / 7 | 1 / 1 | No. 2 | No. 15 |
|
|
C00005138
|
Astragalin
/ Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside |
CHEMBL233930
CHEMBL453290 CHEMBL1572115 |
C001579
|
10 / 6 / 7 | 0 / 1 | No. 2 | No. 15 |
|
|
C00005368
|
Guaijaverin
/ Quercetin 3-O-alpha-L-arabinopyranoside |
CHEMBL183031
CHEMBL185461 CHEMBL488198 CHEMBL464507 CHEMBL520637 |
C088178
|
No. 2 | No. 15 |
|
||
|
C00029500
|
2,4-Dimethoxy-3-hydroxyxanthone
/ 3-Hydroxy-2,4-dimethoxyxanthone |
No. 3 | No. 15 |
|
||||
|
C00008846
|
Catechin-5-O-beta-D-glucopyranoside
/ (+)-Catechin-5-O-beta-D-glucopyranoside |
No. 12 | No. 14 |
|
||||
|
C00008847
|
Epicatechin-5-O-beta-D-glucopyranoside
/ (-)-Epicatechin-5-O-beta-D-glucopyranoside |
No. 12 | No. 14 |
|
||||
|
C00008709
|
Taxifolin 7-glucoside
/ Taxifolin 7-O-beta-D-glucopyranoside / 3,5,7,3',4'-Pentahydroxyflavanone 7-beta-D-glucopyranoside |
No. 12 | No. 14 |
|
||||
|
C00030503
|
Hyperxanthone
|
No. 24 | No. 15 |
|
||||
|
C00019029
|
Tachioside
/ 3-Methoxy-4-hydroxyphenyl-beta-D-glucopyranoside |
CHEMBL1077078
|
No. 45 | No. 72 |
|
|||
|
C00032471
|
Vanilloloside
|
CHEMBL468568
|
1 / 0 / 3 | No. 45 | No. 72 |
|
||
|
C00019030
|
Isotachioside
/ Methoxy-hydroquinone-1-O-beta-D-glucopyranoside / 4-Hydroxy-2-methoxyphenyl-beta-D-Glucopyranoside |
No. 45 | No. 72 |
|
||||
|
C00031274
|
Salidroside
/ Rhodioloside / (-)-Rhodioloside / Tyrosol alpha-(beta-D-glucopyranoside) |
CHEMBL465208
CHEMBL1899113 |
C009172
|
3 / 0 / 0 | No. 45 | No. 72 |
|
|
|
C00030898
|
Osmanthuside F
|
No. 45 | No. 72 |
|
||||
|
C00029501
|
3-Hydroxy-2-methoxyxanthone
|
No. 76 | No. 15 |
|
Human Protein / Gene in interactions
14 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00005137 C00005138 | 1 / 1 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00005137 C00005138 | 0 / 3 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005137 C00005138 | 0 / 0 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005137 C00005138 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005137 C00005138 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005137 C00005138 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00005137 C00005138 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00005137 C00005138 | 4 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00005137 C00005138 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005137 C00005138 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00031274 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00031274 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00031274 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00032471 | 0 / 3 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5320 | PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 | phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) |
C00005137
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|