PCIDB

KNApSAcK Metabolite C00005137

Metabolite

KNApSAcK Entry

id C00005137
Name Trifolin / Kaempferol 3-O-beta-D-galactopyranoside
CAS RN 23627-87-4
Standard InChI InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2/t13-,15+,17?,18?,21+/m1/s1
Standard InChI (Main Layer) InChI=1S/C21H20O11/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8/h1-6,13,15,17-18,21-26,28-29H,7H2

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 2

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL233930 CHEMBL453290 CHEMBL1572115

KEGG

By LinkDB C12626

CTD

By CAS RN C066407

Species

Summary

Plant class

class name count
rosids 14
asterids 12
eudicotyledons 5
Spermatophyta 2
Liliopsida 1
Euphyllophyta 1
Magnoliophyta 1

Family (Top 10)

family name count
Fabaceae 6
Casuarinaceae 3
Asteraceae 3
Pinaceae 2
Euphorbiaceae 2
Saxifragaceae 2
Theaceae 2
Rubiaceae 1
Loganiaceae 1
Geraniaceae 1

List (37)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Abies amabilis 97174 Pinaceae Spermatophyta Viridiplantae
Adiantum monochlamys 872338 Pteridaceae Euphyllophyta Viridiplantae
Adina racemosa 170034 Rubiaceae asterids Viridiplantae
Amsonia ciliata 141529 Apocynaceae asterids Viridiplantae
Annona crassiflora 508206 Annonaceae Magnoliophyta Viridiplantae
Anthyllis onobrychioides 181248 Fabaceae rosids Viridiplantae
Astragalus dipelta 144095 Fabaceae rosids Viridiplantae
Barbacenia rubro-virens 85167 Velloziaceae Liliopsida Viridiplantae
Camellia sinensis 4442 Theaceae asterids Viridiplantae
Camellia sinensis (L.) O.KUNTZE 4441 Theaceae asterids Viridiplantae
Campanula glomerata L. 82281 Campanulaceae asterids Viridiplantae
Carum carvi 48032 Apiaceae asterids Viridiplantae
Casuarina equisetifolia L. 3523 Casuarinaceae rosids Viridiplantae
Casuarina junghaniana 3521 Casuarinaceae rosids Viridiplantae
Casuarina rigida 3521 Casuarinaceae rosids Viridiplantae
Clibadium spp. 183010 Asteraceae asterids Viridiplantae
Consolida oliveriana 984861 Ranunculaceae eudicotyledons Viridiplantae
Desmanthodium spp. 183021 Asteraceae asterids Viridiplantae
Eskemukerjea megacarpum HARA 3615 Polygonaceae eudicotyledons Viridiplantae
Euphorbia condylocarpon 3977 Euphorbiaceae rosids Viridiplantae
Euphorbia lanata 3977 Euphorbiaceae rosids Viridiplantae
Hypericum erectum Thunb. 282539 Hypericaceae rosids Viridiplantae
Leptarrhena pyrolifolia 23253 Saxifragaceae eudicotyledons Viridiplantae
Lespedeza cuneata G. Don 53892 Fabaceae rosids Viridiplantae
Lupinus albus L. 3870 Fabaceae rosids Viridiplantae
Lysimachia nummularia 175113 Primulaceae asterids Viridiplantae
Melochia corchorifolia 133573 Malvaceae rosids Viridiplantae
Monochaetun multiflorum
Opuntia ficus-indica var.saboten 106975 Cactaceae eudicotyledons Viridiplantae
Panax ginseng C.A.Meyer. 4053 Araliaceae asterids Viridiplantae
Pelargonium reniforme 59871 Geraniaceae rosids Viridiplantae
Pinus slyvestris 3318 Pinaceae Spermatophyta Viridiplantae
Saxifraga stellaris 90614 Saxifragaceae eudicotyledons Viridiplantae
Silphium perfoliatum L. 53588 Asteraceae asterids Viridiplantae
Strychnos spinosa 99302 Loganiaceae asterids Viridiplantae
Trifolium pratense 57577 Fabaceae rosids Viridiplantae
Trifolium repens L. 3899 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL1572115 CHEMBL2114784 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1572115 CHEMBL1794585 (1)
0 / 0
P07237 Protein disulfide-isomerase Enzyme CHEMBL233930 CHEMBL1572115 CHEMBL1964080 (2) CHEMBL2114805 (2)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL233930 CHEMBL1942674 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1572115 CHEMBL1794569 (1)
1 / 1
P14679 Tyrosinase Oxidoreductase CHEMBL233930 CHEMBL814345 (1)
4 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL233930 CHEMBL1738588 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL233930 CHEMBL1794483 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL233930 CHEMBL1614211 (1)
0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein CHEMBL233930 CHEMBL2114913 (1)
0 / 3

CTD interaction (1)

compound gene gene name gene description interaction interaction type form reference
pmid
C066407 5320 PLA2G2A
MOM1
PLA2
PLA2B
PLA2L
PLA2S
PLAS1
sPLA2
phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) kaempferol-3-O-galactoside affects the activity of PLA2G2A protein affects activity
protein 8190018

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (7)

KEGG disease name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D004487 C066407 Edema therapeutic
8190018