Species

KNApSAcK Entry

Organism name Lupinus albus L.
Genus Lupinus
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lupinus albus
Linked NCBI taxonomy ID 3870
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036495 External link 512 2'-Hydroxygenistein 7,4'-O-diglucoside
No. 1 No. 15
C00010106 External link 512 Genistein 7,4'-O-diglucoside
/ Genistein 7,4'-di-O-glucoside
/ Genistein-7,4'-di-O-beta-glucopyranoside
No. 1 No. 15
C00005138 External link 512 Astragalin
/ Kaempferol 3-glucoside
/ Kaempferol 3-O-beta-D-glucoside
/ Kaempferol 3-O-beta-D-glucopyranoside
CHEMBL233930
CHEMBL453290
CHEMBL1572115
C001579
10 / 6 / 7 0 / 1 No. 2 No. 15
C00005137 External link 512 Trifolin
/ Kaempferol 3-O-beta-D-galactopyranoside
CHEMBL233930
CHEMBL453290
CHEMBL1572115
C066407
10 / 6 / 7 1 / 1 No. 2 No. 15
C00010119 External link 512 Oroboside
/ Orobol 7-O-glucoside
No. 2 No. 15
C00005525 External link 512 Isorhamnetin 3-glucoside
/ Isorhamnetin 3-O-glucoside
/ Isorhamnetin 3-O-beta-D-glucoside
/ Isorhamnetin 3-O-beta-D-glucopyranoside
CHEMBL234316
CHEMBL516621
1 / 1 / 0 No. 2 No. 15
C00001017 External link 512 Cosmosiin
/ Apigenin 7-glucoside
/ (-)-Apigenin 7-glucoside
/ Apigenin 7-O-beta-D-glucopyranoside
CHEMBL487995
CHEMBL487017
CHEMBL1591566
CHEMBL2165585
C057792
5 / 6 / 1 No. 2 No. 15
C00009453 External link 512 2'-Hydroxygenistein
CHEMBL6665
8 / 6 / 5 No. 71 No. 15

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005137 C00005138 C00009453 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005137 C00005138 C00009453 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005137 C00005138 C00009453 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005137 C00005138 C00009453 1 / 1
P07237 Protein disulfide-isomerase Enzyme C00005137 C00005138 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005137 C00005138 0 / 0
P15121 Aldose reductase Enzyme C00005137 C00005138 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00005137 C00005138 0 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00001017 C00009453 0 / 0
Q99700 Ataxin-2 Unclassified protein C00005137 C00005138 1 / 1
P14679 Tyrosinase Oxidoreductase C00005137 C00005138 4 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001017 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001017 2 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001017 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00009453 1 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00009453 4 / 3
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00005525 1 / 0
P06746 DNA polymerase beta Enzyme C00009453 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001017 4 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5320 PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) C00005137

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#614490 Blood group, junior system; jr Q9UNQ0
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#260540 Parkinson-dementia syndrome P10636
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003876 Dermatitis, Atopic C00005138
D004487 Edema C00005137