Species

KNApSAcK Entry

Organism name Nyctanthes arbortristis
Genus Nyctanthes
Family Oleaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Nyctanthes arbor-tristis
Linked NCBI taxonomy ID 41398
Linked level species

Family

Family in NCBI taxonomy Oleaceae
ID 4144

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005169 External link 512 Nicotiflorin
/ Nicotifloroside
/ Kaempferol 3-O-rutinoside
/ Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside
/ (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside
CHEMBL431610
CHEMBL79790
CHEMBL255020
CHEMBL501550
CHEMBL498879
CHEMBL1419228
CHEMBL1875691
22 / 10 / 12 No. 1 No. 15
C00005138 External link 512 Astragalin
/ Kaempferol 3-glucoside
/ Kaempferol 3-O-beta-D-glucoside
/ Kaempferol 3-O-beta-D-glucopyranoside
CHEMBL233930
CHEMBL453290
CHEMBL1572115
C001579
10 / 6 / 7 0 / 1 No. 2 No. 15
C00037566 External link 512 Nyctanthoside
/ (-)-Nyctanthoside
No. 56 No. 36

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00005138 C00005169 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005138 C00005169 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005138 C00005169 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005138 C00005169 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005138 C00005169 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005138 C00005169 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005169 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005169 1 / 0
P11473 Vitamin D3 receptor NR1I1 C00005169 2 / 3
P39748 Flap endonuclease 1 Enzyme C00005169 0 / 0
O75496 Geminin Unclassified protein C00005169 0 / 0
P15121 Aldose reductase Enzyme C00005138 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005169 1 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005169 1 / 1
P14679 Tyrosinase Oxidoreductase C00005138 4 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005138 0 / 0
P06746 DNA polymerase beta Enzyme C00005169 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00005169 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00005169 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005169 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00005169 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00005169 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00005169 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005169 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00005138 0 / 3
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00005169 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#114500 Colorectal cancer; crc Q14191
#232300 Glycogen storage disease ii P10253
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (17)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003876 Dermatitis, Atopic C00005138