Organism name | Boehmeria holosericea |
---|---|
Genus | Boehmeria |
Family | Urticaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Boehmeria |
---|---|
Linked NCBI taxonomy ID | 83905 |
Linked level | genus |
Family in NCBI taxonomy | Urticaceae |
---|---|
ID | 3499 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00005169
![]() |
Nicotiflorin
/ Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside |
CHEMBL431610
CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691 |
22 / 10 / 12 | No. 1 | No. 15 |
![]() |
||
C00005413
![]() |
Rutin
/ Birutan / 3-Rutinosylquercetin / Quercetin 3-O-rutinoside / (+)-Quercetin 3-O-rutinoside / Quercetin 3-O-beta-rutinoside / (+)-Quercetin 3-O-beta-rutinoside / 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside / Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside |
CHEMBL32579
CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989 |
D012431
|
25 / 18 / 16 | 29 / 8 | No. 1 | No. 15 |
![]() |
C00005372
![]() |
Hyperin
/ Hyperoside / Quercetin 3-O-galactoside / Quercetin 3-O-beta-D-galactoside / Quercetin 3-beta-galactopyranoside / Quercetin 3-O-beta-D-galactopyranoside |
CHEMBL33027
CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 |
C021304
|
38 / 43 / 34 | 4 / 0 | No. 2 | No. 15 |
![]() |
C00005138
![]() |
Astragalin
/ Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside |
CHEMBL233930
CHEMBL453290 CHEMBL1572115 |
C001579
|
10 / 6 / 7 | 0 / 1 | No. 2 | No. 15 |
![]() |
C00003647
![]() |
Campesterol
/ 24alpha-Methylcholesterol / (24R)24-Methylcholest-5-en-3beta-ol |
CHEMBL520535
CHEMBL485421 CHEMBL1836653 |
C021273
|
No. 53 | No. 11 |
![]() |
||
C00023774
![]() |
Fucostanol
/ Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol |
CHEMBL66943
CHEMBL186373 CHEMBL400247 CHEMBL1568947 |
D013265
|
5 / 0 / 0 | 1 / 0 | No. 53 | No. 11 |
![]() |
C00003672
![]() |
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
![]() |
||
C00001238
![]() |
Stearic acid
|
CHEMBL46403
|
C031183
|
15 / 17 / 19 | 6 / 1 | No. 184 | No. 68 |
![]() |
C00001233
![]() |
Palmitic acid
|
CHEMBL82293
|
D019308
|
16 / 8 / 8 | 35 / 1 | No. 184 | No. 68 |
![]() |
C00001224
![]() |
Linoleic acid
/ (Z,Z)-9,12-Octadecadienoic acid |
CHEMBL267476
|
29 / 31 / 28 | No. 367 | No. 68 |
![]() |
||
C00000615
![]() |
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00001224 C00001238 C00005169 C00005372 C00005413 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00000615 C00003672 C00005169 C00005372 C00005413 C00023774 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00005138 C00005169 C00005372 C00005413 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00000615 C00001224 C00001233 C00003672 C00005413 | 1 / 1 |
P14679 | Tyrosinase | Oxidoreductase | C00000615 C00003672 C00005138 C00005372 C00005413 | 4 / 2 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00001224 C00003672 C00005413 | 0 / 1 |
P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 C00005169 C00005372 C00005413 | 1 / 1 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00001224 C00001238 C00003672 | 1 / 1 |
O75496 | Geminin | Unclassified protein | C00001224 C00001233 C00005169 C00005372 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00005169 C00005372 C00005413 | 1 / 1 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 C00001224 C00001238 C00003672 | 3 / 2 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00001224 C00001238 C00005413 | 3 / 3 |
P15121 | Aldose reductase | Enzyme | C00000615 C00005138 C00005372 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000615 C00005372 C00005413 | 0 / 3 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00005372 C00005413 | 0 / 0 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005169 C00005372 C00005413 | 1 / 0 |
P15090 | Fatty acid-binding protein, adipocyte | Other cytosolic protein | C00001224 C00001233 C00001238 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00005372 C00005413 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00005372 C00005413 | 4 / 3 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 C00005372 C00005413 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00005169 C00005372 | 0 / 0 |
P07237 | Protein disulfide-isomerase | Enzyme | C00005138 C00005169 C00005372 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00005138 C00005169 C00005372 | 0 / 0 |
P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001224 C00001233 C00001238 | 2 / 2 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001224 C00001233 C00005413 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00005138 C00005169 C00005372 | 1 / 1 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00005169 C00005372 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00001224 C00005372 | 11 / 10 |
P11473 | Vitamin D3 receptor | NR1I1 | C00001238 C00005169 | 2 / 3 |
P08047 | Transcription factor Sp1 | Unclassified protein | C00001233 C00003672 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005138 C00005169 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001224 C00001238 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 C00001238 | 3 / 1 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00001238 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00003672 | 1 / 1 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00005372 C00005413 | 0 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00001224 | 2 / 2 |
P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 C00001224 | 0 / 0 |
P08183 | Multidrug resistance protein 1 | drug | C00001233 C00003672 | 1 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00003672 | 0 / 1 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 C00005169 | 0 / 0 |
Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00005372 C00005413 | 2 / 0 |
P10275 | Androgen receptor | NR3C4 | C00001224 C00001233 | 3 / 4 |
Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001224 C00001233 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00003672 | 0 / 0 |
P11388 | DNA topoisomerase 2-alpha | Isomerase | C00005413 C00023774 | 0 / 0 |
P05413 | Fatty acid-binding protein, heart | Other cytosolic protein | C00001224 C00001233 | 0 / 0 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 C00001224 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00005138 C00005169 | 1 / 1 |
P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 C00001224 | 0 / 0 |
Q96RI1 | Bile acid receptor | NR1H4 | C00001224 C00001233 | 0 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00001224 | 0 / 0 |
P06280 | Alpha-galactosidase A | Enzyme | C00000615 C00005372 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00000615 C00001238 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00001238 | 1 / 2 |
P04150 | Glucocorticoid receptor | NR3C1 | C00001233 C00001238 | 0 / 1 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00005169 C00005372 | 0 / 1 |
P39748 | Flap endonuclease 1 | Enzyme | C00005169 C00005372 | 0 / 0 |
P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00003672 | 0 / 0 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00005169 C00005372 | 1 / 4 |
Q9UGP5 | DNA polymerase lambda | Enzyme | C00001224 C00001238 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00003672 | 1 / 0 |
P03956 | Interstitial collagenase | M10A | C00000615 | 0 / 1 |
P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00005413 | 0 / 0 |
P12104 | Fatty acid-binding protein, intestinal | Other cytosolic protein | C00001233 | 0 / 0 |
P00915 | Carbonic anhydrase 1 | Lyase | C00000615 | 0 / 0 |
P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
P27487 | Dipeptidyl peptidase 4 | S9B | C00005413 | 0 / 1 |
P41143 | Delta-type opioid receptor | Opioid receptor | C00005372 | 0 / 0 |
P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001238 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001224 | 0 / 0 |
P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00005372 | 0 / 0 |
P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00005372 | 3 / 1 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005169 | 0 / 0 |
Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000615 | 0 / 0 |
P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000615 | 0 / 0 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 | 0 / 0 |
P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00005372 | 1 / 1 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001224 | 5 / 3 |
P06276 | Cholinesterase | Hydrolase | C00005413 | 0 / 0 |
O43570 | Carbonic anhydrase 12 | Lyase | C00000615 | 1 / 2 |
P13726 | Tissue factor | Membrane receptor | C00001224 | 0 / 0 |
Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000615 | 0 / 0 |
P23280 | Carbonic anhydrase 6 | Lyase | C00000615 | 0 / 0 |
P41145 | Kappa-type opioid receptor | Opioid receptor | C00005372 | 0 / 0 |
P10696 | Alkaline phosphatase, placental-like | Enzyme | C00005372 | 0 / 1 |
P11387 | DNA topoisomerase 1 | Isomerase | C00001233 | 0 / 0 |
Q16790 | Carbonic anhydrase 9 | Lyase | C00000615 | 0 / 1 |
P08253 | 72 kDa type IV collagenase | M10A | C00000615 | 1 / 3 |
Q01469 | Fatty acid-binding protein, epidermal | Other cytosolic protein | C00001233 | 0 / 0 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000615 | 1 / 8 |
Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000615 | 0 / 0 |
P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00023774 | 0 / 0 |
Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 | 5 / 2 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00005138 | 0 / 0 |
P00918 | Carbonic anhydrase 2 | Lyase | C00000615 | 1 / 2 |
P09884 | DNA polymerase alpha catalytic subunit | Transferase | C00023774 | 0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00005413 | 1 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00005372 | 0 / 0 |
P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00001224 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00000615 | 2 / 2 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001224 | 0 / 0 |
Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 |
O14842 | Free fatty acid receptor 1 | Free fatty acid receptor | C00001224 | 0 / 0 |
P43166 | Carbonic anhydrase 7 | Lyase | C00000615 | 0 / 0 |
P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000615 | 1 / 0 |
P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000615 | 0 / 0 |
Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000615 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00005372 | 6 / 4 |
P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005372 | 1 / 0 |
Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000615 | 3 / 0 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 | 2 / 2 |
P07451 | Carbonic anhydrase 3 | Lyase | C00000615 | 0 / 0 |
P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005372 | 1 / 1 |
P48147 | Prolyl endopeptidase | S9A | C00005413 | 0 / 0 |
P22748 | Carbonic anhydrase 4 | Lyase | C00000615 | 1 / 1 |
P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
Q12794 | Hyaluronidase-1 | Enzyme | C00000615 | 1 / 2 |
P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 | 0 / 0 |
P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000615 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00005169 | 0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00005372 | 4 / 1 |
Q9NPH5 | NADPH oxidase 4 | Enzyme | C00005372 | 0 / 0 |
P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000615 | 1 / 0 |
O60603 | Toll-like receptor 2 | Membrane receptor | C00001233 | 1 / 1 |
P35610 | Sterol O-acyltransferase 1 | Enzyme | C00001224 | 0 / 0 |
Q02880 | DNA topoisomerase 2-beta | Isomerase | C00023774 | 0 / 0 |
P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
P33527 | Multidrug resistance-associated protein 1 | drugs | C00005413 | 0 / 0 |
P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00005138 | 0 / 3 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00005169 | 2 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001233
C00005372
C00005413
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001233
C00001238
C00005413
|
6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00001233
C00001238
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001233
C00005413
|
9619 | ABCG1, ABC8, WHITE1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
C00001233
C00001238
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001233
C00005413
|
1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00001233
C00001238
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001233
C00005413
|
5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00001233
C00001238
|
10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00001233
C00001238
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001233
C00005413
|
3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00001233
|
405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00005413
|
177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00005413
|
23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00005372
|
847 | CAT | catalase (EC:1.11.1.6) |
C00005413
|
873 | CBR1, CBR, SDR21C1, hCBR1 | carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184) |
C00005413
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00005413
|
3627 | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 | chemokine (C-X-C motif) ligand 10 |
C00005413
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00005413
|
1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00005413
|
1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00005413
|
2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00005413
|
3458 | IFNG, IFG, IFI | interferon, gamma |
C00005413
|
3480 | IGF1R, CD221, IGFIR, IGFR, JTK13 | insulin-like growth factor 1 receptor (EC:2.7.10.1) |
C00005413
|
3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00005413
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00005413
|
3667 | IRS1, HIRS-1 | insulin receptor substrate 1 |
C00005413
|
3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00005413
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00005413
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00005413
|
4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00005413
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00005413
|
2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00005372
|
7039 | TGFA, TFGA | transforming growth factor, alpha |
C00005413
|
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00005372
|
7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00005413
|
10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00023774
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00001233
|
213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00001233
|
840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00001233
|
1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) |
C00001233
|
2876 | GPX1, GPXD, GSHPX1 | glutathione peroxidase 1 (EC:1.11.1.9) |
C00001233
|
3034 | HAL, HIS, HSTD | histidine ammonia-lyase (EC:4.3.1.3) |
C00001233
|
57817 | HAMP, HEPC, HFE2B, LEAP1, PLTR | hepcidin antimicrobial peptide |
C00001233
|
3481 | IGF2, C11orf43, IGF-II, PP9974 | insulin-like growth factor 2 (somatomedin A) |
C00001233
|
196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00005413
|
1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00001233
|
5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00001233
|
5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00001233
|
4493 | MT1E, MT1, MTD | metallothionein 1E |
C00001233
|
4494 | MT1F, MT1 | metallothionein 1F |
C00001233
|
4496 | MT1H, MT-0, MT-1H, MT-IH, MT1 | metallothionein 1H |
C00001233
|
4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00001233
|
4502 | MT2A, MT2 | metallothionein 2A |
C00001233
|
4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) |
C00001233
|
3651 | PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1 | pancreatic and duodenal homeobox 1 |
C00001233
|
29893 | PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP | PSMC3 interacting protein |
C00001233
|
5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
C00001233
|
6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00001233
|
23216 | TBC1D1, TBC, TBC1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
C00001233
|
7351 | UCP2, BMIQ4, SLC25A8, UCPH | uncoupling protein 2 (mitochondrial, proton carrier) |
C00001233
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
#103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
#203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
#606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#218030 | Apparent mineralocorticoid excess; ame |
P80365
|
#613546 | Aromatase deficiency |
P11511
|
#139300 | Aromatase excess syndrome; aexs |
P11511
|
#600807 | Asthma, susceptibility to |
Q13093
|
#614490 | Blood group, junior system; jr |
Q9UNQ0
|
%606641 | Body mass index; bmi |
P37231
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
#114500 | Colorectal cancer; crc |
Q14191
|
#602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
#615363 | Estrogen resistance; estrr |
P03372
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#137800 | Glioma susceptibility 1; glm1 |
P37231
|
#232300 | Glycogen storage disease ii |
P10253
|
#139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#143860 | Hyperchlorhidrosis, isolated |
O43570
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#146300 | Hypophosphatasia, adult |
P05186
|
#241510 | Hypophosphatasia, childhood |
P05186
|
#241500 | Hypophosphatasia, infantile |
P05186
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#147050 | Ige responsiveness, atopic; iger |
Q13093
|
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
#151100 | Leopard syndrome 1 |
Q06124
|
#246300 | Leprosy, susceptibility to, 3; lprs3 |
O60603
|
#601626 | Leukemia, acute myeloid; aml |
P36888
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#156250 | Metachondromatosis; metcds |
Q06124
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
#259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
#163950 | Noonan syndrome 1; ns1 |
Q06124
|
#601665 | Obesity |
P37231
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
#172700 | Pick disease of brain |
P10636
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
#614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
#613679 | Prothrombin deficiency, congenital |
P00734
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#601367 | Stroke, ischemic |
P00734
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278300 | Xanthinuria, type i |
P47989
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
H00344 | Leprosy |
O60603
(related)
|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
|
H00022 | Bladder cancer |
P00533
(related)
|
H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P08253 (related) |
H00030 | Cervical cancer |
P00533
(related)
|
H00042 | Glioma |
P00533
(related)
P00533 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
H00223 | Inherited thrombophilia |
P00734
(related)
|
H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
H00082 | Graves' disease |
P01215
(marker)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
P16473 (related) |
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
|
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
H00213 | Hypophosphatasia |
P05186
(related)
|
H00125 | Fabry disease |
P06280
(related)
|
H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
H00472 | Torg-Winchester syndrome |
P08253
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00023 | Testicular cancer |
P10696
(marker)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00794 | Aromatase excess syndrome |
P11511
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
H00038 | Malignant melanoma |
P14679
(marker)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
H00032 | Thyroid cancer |
P27487
(marker)
P37231 (related) |
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
H00046 | Cholangiocarcinoma |
P35354
(related)
|
H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00192 | Xanthinuria |
P47989
(related)
|
H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
H01018 | Metachondromatosis |
Q06124
(related)
|
H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00296 | Defects in RecQ helicases |
Q14191
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D003072 | Cognition Disorders |
C00001238
C00001233 |
D015212 | Inflammatory Bowel Diseases |
C00005413
|
D001424 | Bacterial Infections |
C00005413
|
D003092 | Colitis |
C00005413
|
D004409 | Dyskinesia, Drug-Induced |
C00005413
|
D003876 | Dermatitis, Atopic |
C00005138
|
D007674 | Kidney Diseases |
C00005413
|
D028361 | Mitochondrial Diseases |
C00005413
|
D010243 | Paralysis |
C00005413
|
D013276 | Stomach Ulcer |
C00005413
|