KNApSAcK Entry

Organism name Arnica montana cv.ARBO
Genus Arnica
Family Asteraceae
Kingdom Plantae

NCBI taxonomy


Linked NCBI taxonomy name Arnica
Linked NCBI taxonomy ID 4246
Linked level genus


Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
C00005141 External link 512 Kaempferol 3-glucuronide
/ Kaempferol-3-O-beta-D-glucuronide
No. 2 No. 15
C00005639 External link 512 Patuletin 3-glucoside
/ Patuletin 3-O-beta-D-glucoside
No. 2 No. 15
C00005373 External link 512 Hirsutrin
/ Isoquercetin
/ Isoquercetrin
/ (-)-Isoquercetrin
/ Quercetin 3-glucoside
/ Quercetin 3-O-beta-D-glucoside
/ Quercetin-3-O-beta-D-glucopyranoside
/ Quercetin 3-O-beta-D-glucopyranoside
/ (-)-Quercetin-3-O-beta-D-glucopyranoside
38 / 43 / 34 No. 2 No. 15
C00005138 External link 512 Astragalin
/ Kaempferol 3-glucoside
/ Kaempferol 3-O-beta-D-glucoside
/ Kaempferol 3-O-beta-D-glucopyranoside
10 / 6 / 7 0 / 1 No. 2 No. 15
C00001050 External link 512 Dinatin
/ Hispidulin
/ 6-Methoxyapigenin
/ 6-O-Methylapigenin
32 / 34 / 59 0 / 1 No. 3 No. 15
C00002724 External link 512 Heriguard
/ Chlorogenic acid
/ 3-O-Caffeoylquinic acid
30 / 19 / 22 37 / 9 No. 314 No. 6
C00034862 External link 512 Isobutyryl helenalin
3 / 0 / 0 No. 470 No. 38
C00003298 External link 512 Helenalin
37 / 36 / 29 18 / 3 No. 495 No. 38
C00034768 External link 512 sochlorogenic acid c
/ 4,5-Dicaffeoylquinic acid
2 / 0 / 0 No. 518 No. 6
C00029481 External link 512 3,5-di-O-caffeate
/ sochlorogenic acid a
/ 3,5-Dicaffeoylquinic acid
2 / 0 / 0 No. 518 No. 6
C00003352 External link 512 Plenolin
/ Dihydrohelenalin
/ 11,13-Dihydrohelenalin
3 / 0 / 0 No. 755 No. 38

Human Protein / Gene in interactions

109 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
P15121 Aldose reductase Enzyme C00002724 C00005138 C00005373 C00029481 C00034768 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001050 C00002724 C00005138 C00005373 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002724 C00003298 C00005373 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00003298 C00003352 C00034862 0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor C00003298 C00003352 C00034862 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001050 C00002724 C00003298 1 / 1
Q9Y253 DNA polymerase eta Enzyme C00003298 C00005138 C00005373 1 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003298 C00003352 C00034862 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00002724 C00029481 C00034768 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001050 C00003298 C00005138 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00003298 C00005138 C00005373 0 / 0
O75496 Geminin Unclassified protein C00002724 C00003298 C00005373 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001050 C00003298 C00005373 4 / 3
P06746 DNA polymerase beta Enzyme C00001050 C00003298 C00005373 0 / 0
P04062 Glucosylceramidase Enzyme C00001050 C00003298 C00005373 6 / 4
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002724 C00003298 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001050 C00005373 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002724 C00005373 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002724 C00005373 0 / 3
O15118 Niemann-Pick C1 protein Unclassified protein C00001050 C00003298 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00003298 C00005373 0 / 0
P06280 Alpha-galactosidase A Enzyme C00003298 C00005373 1 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002724 C00003298 0 / 0
Q99700 Ataxin-2 Unclassified protein C00003298 C00005138 1 / 1
Q16637 Survival motor neuron protein Unclassified protein C00003298 C00005373 4 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002724 C00005373 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005138 C00005373 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00001050 C00003298 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003298 C00005138 0 / 3
P14679 Tyrosinase Oxidoreductase C00005138 C00005373 4 / 2
P41145 Kappa-type opioid receptor Opioid receptor C00005373 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00005373 1 / 1
P39748 Flap endonuclease 1 Enzyme C00005373 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00003298 0 / 0
P42858 Huntingtin Unclassified protein C00003298 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003298 2 / 0
P11473 Vitamin D3 receptor NR1I1 C00003298 2 / 3
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005373 1 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002724 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00003298 4 / 2
Q9Y2T6 G-protein coupled receptor 55 Lysophosphatidylinositol receptor C00003298 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00005373 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002724 0 / 1
P10145 Interleukin-8 Secreted protein C00002724 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002724 1 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003298 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00005373 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005373 1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme C00005373 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00005373 3 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00003298 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00003298 0 / 0
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00001050 2 / 2
P04150 Glucocorticoid receptor NR3C1 C00002724 0 / 1
P30556 Type-1 angiotensin II receptor Angiotensin receptor C00003298 1 / 1
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002724 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00002724 3 / 2
P55789 FAD-linked sulfhydryl oxidase ALR Enzyme C00001050 1 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00005373 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002724 0 / 0
Q00987 E3 ubiquitin-protein ligase Mdm2 Other nuclear protein C00003298 1 / 5
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002724 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00005373 2 / 0
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002724 1 / 1
P02545 Prelamin-A/C Unclassified protein C00005373 11 / 10
Q9Y5X4 Photoreceptor-specific nuclear receptor NR2E3 C00003298 2 / 2
P35372 Mu-type opioid receptor Opioid receptor C00005373 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002724 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002724 0 / 1
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00001050 1 / 4
O75164 Lysine-specific demethylase 4A Enzyme C00002724 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005138 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005373 1 / 1
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002724 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002724 3 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00005373 1 / 0
P06239 Tyrosine-protein kinase Lck Src C00002724 0 / 1
P34949 Mannose-6-phosphate isomerase Enzyme C00005373 1 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00001050 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002724 2 / 2
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002724 3 / 3
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003298 2 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00005373 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003298 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00003298 0 / 0
O00255 Menin Unclassified protein C00001050 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001050 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00005373 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00005373 1 / 4
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00001050 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00001050 1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00001050 1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00001050 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00001050 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00001050 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00001050 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00001050 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00001050 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00001050 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00001050 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00001050 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00001050 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00001050 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00001050 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00001050 1 / 0
P17861 X-box-binding protein 1 Unclassified protein C00003298 1 / 0
Q9NPH5 NADPH oxidase 4 Enzyme C00005373 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00001050 7 / 37
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002724 1 / 0

55 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
468 ATF4, CREB-2, CREB2, TAXREB67, TXREB activating transcription factor 4 C00003298
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC: C00003298
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC: C00003298
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00003298
941 CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 CD80 molecule C00003298
9308 CD83, BL11, HB15 CD83 molecule C00003298
942 CD86, B7-2, B7.2, B70, CD28LG2, LAB72 CD86 molecule C00003298
1649 DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 DNA-damage-inducible transcript 3 C00003298
54541 DDIT4, Dig2, REDD-1, REDD1 DNA-damage-inducible transcript 4 C00003298
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00003298
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00003298
3592 IL12A, CLMF, IL-12A, NFSK, NKSF1, P35 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) C00003298
3593 IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) C00003298
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00003298
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00003298
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00003298
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC: C00003298
8797 TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1 tumor necrosis factor receptor superfamily, member 10a C00003298
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC: C00002724
358 AQP1, AQP-CHIP, CHIP28, CO aquaporin 1 C00002724
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00002724
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00002724
960 CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 CD44 molecule (Indian blood group) C00002724
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00002724
1277 COL1A1, OI4 collagen, type I, alpha 1 C00002724
4512 COX1, COI, MTCO1, MT-CO1 cytochrome c oxidase subunit I C00002724
114757 CYGB, HGB, STAP cytoglobin C00002724
1830 DSG3, CDHF6, PVA desmoglein 3 C00002724
1950 EGF, HOMG4, URG epidermal growth factor C00002724
2200 FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 fibrillin 1 C00002724
2201 FBN2, CCA, DA9 fibrillin 2 C00002724
2246 FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 fibroblast growth factor 1 (acidic) C00002724
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00002724
3036 HAS1, HAS hyaluronan synthase 1 (EC: C00002724
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00002724
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002724
3852 KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A keratin 5 C00002724
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00002724
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC: C00002724
5241 PGR, NR3C3, PR progesterone receptor C00002724
8985 PLOD3, LH3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC: C00002724
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00002724
5886 RAD23A, HHR23A, HR23A RAD23 homolog A (S. cerevisiae) C00002724
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00002724
6256 RXRA, NR2B1 retinoid X receptor, alpha C00002724
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC: C00002724
6716 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC: C00002724
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00002724
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00002724
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC: C00002724
7306 TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN tyrosinase-related protein 1 (EC:1.14.18.-) C00002724
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC: C00002724
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC: C00002724
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC: C00002724
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC: C00002724

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (103)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300018 46,xy sex reversal 2; srxy2 P51843
#614401 Accelerated tumor formation, susceptibility to; actfs Q00987
#300200 Adrenal hypoplasia, congenital; ahc P51843
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P47869
#600807 Asthma, susceptibility to Q13093
#208900 Ataxia-telangiectasia; at Q13315
#209950 Atypical mycobacteriosis, familial P42224
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#614490 Blood group, junior system; jr Q9UNQ0
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#614162 Candidiasis, familial, 7; candf7 P42224
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#268100 Enhanced s-cone syndrome; escs Q9Y5X4
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#133239 Esophageal cancer P04637
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#245590 Growth hormone insensitivity with immunodeficiency P51692
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P04637
#612371 Major affective disorder 7; mafd7 P17861
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#613076 Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay P55789
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#267430 Renal tubular dysgenesis; rtd P30556
#275210 Restrictive dermopathy, lethal P02545
#611131 Retinitis pigmentosa 37; rp37 Q9Y5X4
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253


KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
P16473 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
Q13315 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
P40763 (related)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
Q00987 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
Q00987 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
Q00987 (related)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
Q00987 (related)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00213 Hypophosphatasia P05186 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00575 Renal tubular dysgenesis P30556 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00192 Xanthinuria P47989 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00037 Alveolar rhabdomyosarcoma Q00987 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)
H00527 Retinitis pigmentosa (RP) Q9Y5X4 (related)
H00805 Vitreoretinal degeneration Q9Y5X4 (related)

Diseases related to CTD interactions

14 disease in interactions with metabolites

D002292 Carcinoma, Renal Cell C00003298
D003110 Colonic Neoplasms C00003298
D007249 Inflammation C00003298
D003876 Dermatitis, Atopic C00005138
D004487 Edema C00001050
D000647 Amnesia C00002724
D056486 Drug-Induced Liver Injury C00002724
D006937 Hypercholesterolemia C00002724
D006951 Hyperlipoproteinemias C00002724
D015228 Hypertriglyceridemia C00002724
D052456 Hypoalphalipoproteinemias C00002724
D008545 Melanoma C00002724
D009336 Necrosis C00002724
D015431 Weight Loss C00002724