Species

KNApSAcK Entry

Organism name Stenochlaena palustris
Genus Stenochlaena
Family Blechnaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stenochlaena palustris
Linked NCBI taxonomy ID 32079
Linked level species

Family

Family in NCBI taxonomy Blechnaceae
ID 29600

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Euphyllophyta
ID 78536

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005138 External link 512 Astragalin
/ Kaempferol 3-glucoside
/ Kaempferol 3-O-beta-D-glucoside
/ Kaempferol 3-O-beta-D-glucopyranoside
CHEMBL233930
CHEMBL453290
CHEMBL1572115
C001579
10 / 6 / 7 0 / 1 No. 2 No. 15
C00003776 External link 512 Lutein
/ (all-E)-Lutein
/ all-trans-(+)-Xanthophyll
/ (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol
CHEMBL173929
CHEMBL172477
CHEMBL1559643
CHEMBL1979448
D014975
4 / 2 / 3 7 / 2 No. 26 No. 59
C00049311 External link 512 Stenopalustroside D
CHEMBL452961
CHEMBL446770
No. 231
C00013776 External link 512 Stenopalustroside A
/ Kaempfero 3-(3'',6''-di-(Z)-p-coumaroylglucoside)
/ 3-[[3,6-bis-O-[(2Z)-3-(4-Hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL452961
CHEMBL446770
No. 231
C00049310 External link 512 Stenopalustroside C
CHEMBL452961
CHEMBL446770
No. 231
C00049309 External link 512 Stenopalustroside B
/ (-)-Stenopalustroside B
CHEMBL510341
CHEMBL461206
No. 231
C00049312 External link 512 Stenopalustroside E
CHEMBL500228
No. 231
C00019308 External link 512 Doursterol
/ Daucosterin
/ 3-O-beta-D-Glucopyranosyl sitosterol
/ beta-Sitosterol 3-O-beta-D-glucopyranoside
CHEMBL197711
CHEMBL506678
CHEMBL2304043
C011015
5 / 4 / 2 0 / 3 No. 520
C00041126 External link 512 Stenopaluside
/ (-)-Stenopaluside
No. 8527

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00019308 0 / 0
Q99700 Ataxin-2 Unclassified protein C00005138 1 / 1
P06746 DNA polymerase beta Enzyme C00019308 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005138 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00019308 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005138 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003776 2 / 3
O75496 Geminin Unclassified protein C00003776 0 / 0
P15121 Aldose reductase Enzyme C00005138 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00019308 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005138 1 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003776 0 / 0
P00734 Prothrombin S1A C00019308 4 / 2
P14679 Tyrosinase Oxidoreductase C00005138 4 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005138 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005138 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005138 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003776 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00005138 0 / 3

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00003776
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00003776
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00003776
847 CAT catalase (EC:1.11.1.6) C00003776
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00003776
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00003776
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00003776

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (12)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003876 Dermatitis, Atopic C00005138
D002493 Central Nervous System Diseases C00019308
D003072 Cognition Disorders C00019308
D013118 Spinal Cord Diseases C00019308
D007939 Leukemia L1210 C00003776
D014605 Uveitis C00003776