| Organism name | Clitoria ternata | 
|---|---|
| Genus | Clitoria | 
| Family | Fabaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Clitoria | 
|---|---|
| Linked NCBI taxonomy ID | 43365 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Fabaceae | 
|---|---|
| ID | 3803 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00007247   | Linolenic acid / alpha-Linolenic acid / (Z,Z,Z)-Octadeca-9,12,15-trienoic acid | D017962 | 22 / 5 |   | ||||
| C00005169   | Nicotiflorin / Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside | CHEMBL431610 CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691 | 22 / 10 / 12 | No. 1 | No. 15 |   | ||
| C00005167   | Kaempferol 3-neohesperidoside | CHEMBL507493 | No. 1 | No. 15 |   | |||
| C00005138   | Astragalin / Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside | CHEMBL233930 CHEMBL453290 CHEMBL1572115 | C001579 | 10 / 6 / 7 | 0 / 1 | No. 2 | No. 15 |   | 
| C00005219   | Clitorin / Kaempferol 3-(2G-rhamnosylrutinoside) | CHEMBL362593 CHEMBL1454324 CHEMBL2005346 | C077190 | 1 / 0 / 0 | No. 5 | No. 15 |   | |
| C00031394   | Stigmast 4-ene 3,6-dione / (-)-Stigmast 4-ene 3,6-dione | C017726 | No. 53 | No. 11 |   | |||
| C00001238   | Stearic acid | CHEMBL46403 | C031183 | 15 / 17 / 19 | 6 / 1 | No. 184 | No. 68 |   | 
| C00001233   | Palmitic acid | CHEMBL82293 | D019308 | 16 / 8 / 8 | 35 / 1 | No. 184 | No. 68 |   | 
| C00001232   | Oleic acid / (Z)-9-Octadecenoic acid | CHEMBL8659 CHEMBL460657 | D019301 | 30 / 19 / 20 | 26 / 9 | No. 184 | No. 68 |   | 
| C00001209   | Arachidic acid / Eicosanoic acid | CHEMBL1173381 | C094477 | No. 184 | No. 68 |   | ||
| C00001224   | Linoleic acid / (Z,Z)-9,12-Octadecadienoic acid | CHEMBL267476 | 29 / 31 / 28 | No. 367 | No. 68 |   | ||
| C00001211   | Behenic acid | CHEMBL1173474 | C007547 | No. 1100 | No. 68 |   | ||
| C00001223   | Lignoceric acid | CHEMBL1173620 | C010210 | 1 / 0 | No. 1100 | No. 68 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P15090 | Fatty acid-binding protein, adipocyte | Other cytosolic protein | C00001224 C00001232 C00001233 C00001238 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00001224 C00001232 C00001233 C00005169 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001224 C00001232 C00001238 C00005169 | 0 / 0 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001224 C00001232 C00001233 C00001238 | 2 / 2 | 
| Q9UGP5 | DNA polymerase lambda | Enzyme | C00001224 C00001232 C00001238 | 0 / 0 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001224 C00001232 C00001233 | 0 / 0 | 
| P11387 | DNA topoisomerase 1 | Isomerase | C00001232 C00001233 C00005219 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001232 C00005138 C00005169 | 0 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001224 C00001232 C00001233 | 0 / 0 | 
| Q96RI1 | Bile acid receptor | NR1H4 | C00001224 C00001232 C00001233 | 0 / 0 | 
| P05413 | Fatty acid-binding protein, heart | Other cytosolic protein | C00001224 C00001232 C00001233 | 0 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001224 C00001232 C00001238 | 3 / 3 | 
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001224 C00001238 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00001224 C00001233 | 1 / 1 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001232 C00005138 | 0 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001224 C00001238 | 3 / 2 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005138 C00005169 | 0 / 0 | 
| Q01469 | Fatty acid-binding protein, epidermal | Other cytosolic protein | C00001232 C00001233 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005138 C00005169 | 0 / 0 | 
| P13726 | Tissue factor | Membrane receptor | C00001224 C00001232 | 0 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001224 C00001232 | 5 / 3 | 
| P07237 | Protein disulfide-isomerase | Enzyme | C00005138 C00005169 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001232 C00005169 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00001233 C00001238 | 0 / 1 | 
| P10275 | Androgen receptor | NR3C4 | C00001224 C00001233 | 3 / 4 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00001238 C00005169 | 2 / 3 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00005138 C00005169 | 1 / 1 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001232 C00001238 | 1 / 2 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00005138 C00005169 | 1 / 1 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001224 C00001232 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001224 C00001238 | 1 / 1 | 
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001232 C00001238 | 0 / 0 | 
| P35610 | Sterol O-acyltransferase 1 | Enzyme | C00001224 C00001232 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001238 | 0 / 0 | 
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00001232 | 0 / 0 | 
| P15121 | Aldose reductase | Enzyme | C00005138 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00005169 | 0 / 0 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005169 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001224 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001232 | 0 / 0 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001224 | 0 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005169 | 1 / 0 | 
| P54132 | Bloom syndrome protein | Enzyme | C00001232 | 1 / 2 | 
| P14679 | Tyrosinase | Oxidoreductase | C00005138 | 4 / 2 | 
| P08183 | Multidrug resistance protein 1 | drug | C00001233 | 1 / 0 | 
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00001224 | 0 / 0 | 
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00001224 | 0 / 0 | 
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00001224 | 0 / 0 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001238 | 3 / 1 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00005169 | 1 / 1 | 
| P07148 | Fatty acid-binding protein, liver | Unclassified protein | C00001232 | 0 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001224 | 2 / 2 | 
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00001232 | 0 / 0 | 
| P08047 | Transcription factor Sp1 | Unclassified protein | C00001233 | 0 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00001224 | 11 / 10 | 
| P12104 | Fatty acid-binding protein, intestinal | Other cytosolic protein | C00001233 | 0 / 0 | 
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00001232 | 1 / 4 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001224 | 0 / 1 | 
| O14842 | Free fatty acid receptor 1 | Free fatty acid receptor | C00001224 | 0 / 0 | 
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001224 | 0 / 0 | 
| P17252 | Protein kinase C alpha type | Alpha | C00001232 | 0 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00005169 | 1 / 1 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001232 | 4 / 3 | 
| P06746 | DNA polymerase beta | Enzyme | C00005169 | 0 / 0 | 
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001232 | 2 / 2 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00005169 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00005169 | 0 / 0 | 
| O60603 | Toll-like receptor 2 | Membrane receptor | C00001233 | 1 / 1 | 
| O00255 | Menin | Unclassified protein | C00001238 | 2 / 5 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00005169 | 0 / 1 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00005169 | 1 / 4 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005169 | 0 / 0 | 
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00005138 | 0 / 3 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00005169 | 2 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 | C00001223
                          C00001232
                          C00001233
                          C00001238 | 
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha | C00001232
                          C00001233
                          C00001238
                          C00007247 | 
| 9619 | ABCG1, ABC8, WHITE1 | ATP-binding cassette, sub-family G (WHITE), member 1 | C00001232
                          C00001233
                          C00001238 | 
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 | C00001232
                          C00001233
                          C00001238 | 
| 1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) | C00001233
                          C00007247 | 
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | C00001233
                          C00001238 | 
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor | C00001232
                          C00001233 | 
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 | C00001233
                          C00001238 | 
| 5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | C00001232
                          C00001233 | 
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin | C00001232
                          C00001233 | 
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin | C00001232
                          C00001233 | 
| 6256 | RXRA, NR2B1 | retinoid X receptor, alpha | C00001232
                          C00007247 | 
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma | C00001232
                          C00007247 | 
| 5467 | PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB | peroxisome proliferator-activated receptor delta | C00001232
                          C00007247 | 
| 100136658 | C00001232
                          C00007247 | ||
| 3034 | HAL, HIS, HSTD | histidine ammonia-lyase (EC:4.3.1.3) | C00001233 | 
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) | C00007247 | 
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta | C00007247 | 
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 | C00007247 | 
| 3827 | KNG1, BDK, BK, KNG | kininogen 1 | C00007247 | 
| 9971 | NR1H4, BAR, FXR, HRR-1, HRR1, RIP14 | nuclear receptor subfamily 1, group H, member 4 | C00007247 | 
| 3992 | FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12 | fatty acid desaturase 1 (EC:1.14.19.-) | C00007247 | 
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | C00007247 | 
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | C00007247 | 
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) | C00007247 | 
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | C00007247 | 
| 7421 | VDR, NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor | C00007247 | 
| 19 | ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD | ATP-binding cassette, sub-family A (ABC1), member 1 | C00001232 | 
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 | C00001232 | 
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | C00007247 | 
| 335 | APOA1 | apolipoprotein A-I | C00001232 | 
| 338 | APOB, FLDB, LDLCQ4 | apolipoprotein B | C00001232 | 
| 847 | CAT | catalase (EC:1.11.1.6) | C00001232 | 
| 1401 | CRP, PTX1 | C-reactive protein, pentraxin-related | C00001232 | 
| 1869 | E2F1, E2F-1, RBAP1, RBBP3, RBP3 | E2F transcription factor 1 | C00001232 | 
| 1591 | CYP24A1, CP24, CYP24, HCAI, P450-CC24 | cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) | C00007247 | 
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) | C00001232 | 
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) | C00001232 | 
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) | C00001232 | 
| 778733 | C00001232 | ||
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 | C00001232 | 
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | C00007247 | 
| 6514 | SLC2A2, GLUT2 | solute carrier family 2 (facilitated glucose transporter), member 2 | C00001232 | 
| 6720 | SREBF1, SREBP-1c, SREBP1, bHLHd1 | sterol regulatory element binding transcription factor 1 | C00001232 | 
| 8647 | ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | C00007247 | 
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | C00001233 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00001233 | 
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 | C00001233 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00001233 | 
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | C00001233 | 
| 2876 | GPX1, GPXD, GSHPX1 | glutathione peroxidase 1 (EC:1.11.1.9) | C00001233 | 
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) | C00007247 | 
| 57817 | HAMP, HEPC, HFE2B, LEAP1, PLTR | hepcidin antimicrobial peptide | C00001233 | 
| 3481 | IGF2, C11orf43, IGF-II, PP9974 | insulin-like growth factor 2 (somatomedin A) | C00001233 | 
| 1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) | C00001233 | 
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) | C00001233 | 
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) | C00001233 | 
| 4493 | MT1E, MT1, MTD | metallothionein 1E | C00001233 | 
| 4494 | MT1F, MT1 | metallothionein 1F | C00001233 | 
| 4496 | MT1H, MT-0, MT-1H, MT-IH, MT1 | metallothionein 1H | C00001233 | 
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X | C00001233 | 
| 4502 | MT2A, MT2 | metallothionein 2A | C00001233 | 
| 4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) | C00001233 | 
| 3651 | PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1 | pancreatic and duodenal homeobox 1 | C00001233 | 
| 29893 | PSMC3IP, GT198, HOP2, HUMGT198A, ODG3, TBPIP | PSMC3 interacting protein | C00001233 | 
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A | C00001233 | 
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) | C00001233 | 
| 23216 | TBC1D1, TBC, TBC1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | C00001233 | 
| 7351 | UCP2, BMIQ4, SLC25A8, UCPH | uncoupling protein 2 (mitochondrial, proton carrier) | C00001233 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #103470 | Albinism, ocular, with sensorineural deafness | P14679 | 
| #203100 | Albinism, oculocutaneous, type ia; oca1a | P14679 | 
| #606952 | Albinism, oculocutaneous, type ib; oca1b | P14679 | 
| #300068 | Androgen insensitivity syndrome; ais | P10275 | 
| #312300 | Androgen insensitivity, partial; pais | P10275 | 
| #613546 | Aromatase deficiency | P11511 | 
| #139300 | Aromatase excess syndrome; aexs | P11511 | 
| #208900 | Ataxia-telangiectasia; at | Q13315 | 
| #210900 | Bloom syndrome; blm | P54132 | 
| %606641 | Body mass index; bmi | P37231 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #114500 | Colorectal cancer; crc | Q14191 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137800 | Glioma susceptibility 1; glm1 | P37231 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #246300 | Leprosy, susceptibility to, 3; lprs3 | O60603 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #613688 | Long qt syndrome 2; lqt2 | Q12809 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #601665 | Obesity | P37231 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | Q01196 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #609620 | Short qt syndrome 1; sqt1 | Q12809 | 
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | P14679 | 
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 | P10275 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| #277700 | Werner syndrome; wrn | Q14191 | 
| #278300 | Xanthinuria, type i | P47989 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00344 | Leprosy | O60603
                            (related) | 
| H00081 | Hashimoto's thyroiditis | P01215
                            (marker) | 
| H00082 | Graves' disease | P01215
                            (marker) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P01215
                            (marker) P16473 (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) P37231 (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) P11511 (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00024 | Prostate cancer | P10275
                            (related) | 
| H00062 | Spinal and bulbar muscular atrophy (SBMA) | P10275
                            (related) | 
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) | P10275
                            (related) | 
| H00609 | 46,XY disorders of sex development (Other) | P10275
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00794 | Aromatase excess syndrome | P11511
                            (related) | 
| H00168 | Oculocutaneous albinism (OCA) | P14679
                            (related) | 
| H00038 | Malignant melanoma | P14679
                            (marker) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00094 | DNA repair defects | P54132
                            (related) Q13315 (related) | 
| H00296 | Defects in RecQ helicases | P54132
                            (related) Q14191 (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q01196
                            (related) Q01196 (marker) Q03164 (related) Q03164 (marker) | 
| H00003 | Acute myeloid leukemia (AML) | Q01196
                            (related) Q01196 (marker) Q13951 (marker) | 
| H00004 | Chronic myeloid leukemia (CML) | Q01196
                            (related) | 
| H00978 | Thrombocytopenia (THC) | Q01196
                            (related) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00720 | Long QT syndrome | Q12809
                            (related) | 
| H00725 | Short QT syndrome | Q12809
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | Q13315
                            (related) | 
| H00064 | Ataxia telangiectasia (AT) | Q13315
                            (related) | 
| H00848 | Ataxia with ocular apraxia (AOA) | Q13315
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) Q9NUW8 (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D003072 | Cognition Disorders | C00001238 C00001232 C00001233 | 
| D055371 | Acute Lung Injury | C00001232 | 
| D001930 | Brain Injuries | C00007247 | 
| D003866 | Depressive Disorder | C00007247 | 
| D064420 | Drug-Related Side Effects and Adverse Reactions | C00007247 | 
| D007249 | Inflammation | C00007247 | 
| D009422 | Nervous System Diseases | C00007247 | 
| D003876 | Dermatitis, Atopic | C00005138 | 
| D000860 | Anoxia | C00001232 | 
| D005234 | Fatty Liver | C00001232 | 
| D006520 | Hepatitis, Animal | C00001232 | 
| D007333 | Insulin Resistance | C00001232 | 
| D055370 | Lung Injury | C00001232 | 
| D011654 | Pulmonary Edema | C00001232 | 
| D012128 | Respiratory Distress Syndrome, Adult | C00001232 |