Tetrapanax papyriferus

• Index
• Plant Species
• Metabolite list (9)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Tetrapanax papyriferus
Genus	Tetrapanax
Family	Araliaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Tetrapanax papyrifer
Linked NCBI taxonomy ID	46417
Linked level	species

Family

Family in NCBI taxonomy	Araliaceae
ID	4050

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (9)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005140	Afzelin / Kaempferol 3-O-alpha-rhamnoside / Kaempferol 3-O-alpha-L-rhamnopyranoside	CHEMBL240528 CHEMBL515798	C477954	4 / 2 / 2		No. 2	No. 15
C00005138	Astragalin / Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside	CHEMBL233930 CHEMBL453290 CHEMBL1572115	C001579	10 / 6 / 7	0 / 1	No. 2	No. 15
C00034622	Papyriogenin A		C038914			No. 13	No. 51
C00004565	Kaempferol / Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL150	C006552	76 / 69 / 87	86 / 8	No. 71	No. 15
C00042023	1,2,3-Trimethoxybenzene		C091694			No. 856
C00000170	trans-Cinnamate / trans-Cinnamic acid	CHEMBL27246		5 / 2 / 2		No. 904	No. 6
C00002460	Coumarin	CHEMBL6466	C030123	122 / 60 / 55	11 / 7	No. 1030	No. 25
C00042390	Cinnamyl alcohol	CHEMBL118958 CHEMBL324794	C020722	4 / 2 / 1	32 / 1	No. 2320	No. 6
C00042152	5-Formylbenzofuran					No. 2878

Human Protein / Gene in interactions

188 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P15121	Aldose reductase	Enzyme	C00000170 C00002460 C00004565 C00005138	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002460 C00004565 C00005140	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000170 C00004565 C00042390	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002460 C00004565 C00005138	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002460 C00004565 C00005140	0 / 1
P03372	Estrogen receptor	NR3A1	C00000170 C00002460 C00004565	1 / 1
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00004565 C00005140	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00004565 C00005138	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00004565 C00005138	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002460 C00004565	1 / 1
P22303	Acetylcholinesterase	Hydrolase	C00002460 C00004565	1 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002460 C00004565	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002460 C00004565	2 / 2
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002460 C00004565	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002460 C00004565	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002460 C00004565	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00004565 C00005138	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00002460 C00004565	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002460 C00004565	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00004565 C00005138	1 / 1
P10275	Androgen receptor	NR3C4	C00002460 C00004565	3 / 4
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002460 C00004565	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002460 C00004565	1 / 8
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002460 C00004565	0 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002460 C00004565	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00002460 C00004565	11 / 10
P35372	Mu-type opioid receptor	Opioid receptor	C00002460	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005138	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002460	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00004565	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002460	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00002460	3 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00004565	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002460	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002460	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002460	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00002460	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00002460	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00002460	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00002460	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00002460	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00002460	0 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00004565	1 / 0
P02768	Serum albumin	Secreted protein	C00002460	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00004565	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00004565	0 / 0
P08183	Multidrug resistance protein 1	drug	C00004565	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00002460	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002460	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00002460	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00002460	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00004565	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00004565	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005138	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002460	1 / 0
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00004565	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00002460	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00004565	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00002460	2 / 0
P29466	Caspase-1	C14	C00002460	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00002460	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00002460	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00002460	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00002460	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002460	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00002460	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00004565	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00002460	1 / 1
P17538	Chymotrypsinogen B	S1A	C00002460	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00004565	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002460	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00002460	1 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002460	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00004565	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002460	1 / 2
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00004565	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002460	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00004565	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00000170	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00004565	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00042390	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00002460	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00002460	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00002460	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00002460	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00002460	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00002460	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00002460	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00002460	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002460	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00002460	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00002460	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00002460	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002460	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00002460	0 / 0
P08311	Cathepsin G	S1A	C00002460	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00004565	0 / 1
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00002460	1 / 0
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00004565	1 / 1
P03956	Interstitial collagenase	M10A	C00002460	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00002460	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002460	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00002460	1 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002460	0 / 0
P04062	Glucosylceramidase	Enzyme	C00004565	6 / 4
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00002460	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00002460	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00002460	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002460	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00002460	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00004565	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002460	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00002460	1 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00004565	4 / 4
P16083	Ribosyldihydronicotinamide dehydrogenase [quinone]	Enzyme	C00005140	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00002460	0 / 0
P06276	Cholinesterase	Hydrolase	C00004565	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00002460	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00002460	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00002460	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00004565	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00002460	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00002460	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002460	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00002460	2 / 1
P56817	Beta-secretase 1	A1A	C00002460	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00002460	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002460	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00004565	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004565	2 / 0
O75762	Transient receptor potential cation channel subfamily A member 1	Unclassified protein	C00042390	1 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00004565	2 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00004565	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00005138	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00042390	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00002460	0 / 0
P08246	Neutrophil elastase	S1A	C00002460	2 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00002460	1 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002460	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00002460	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00002460	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00002460	2 / 2
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00002460	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00002460	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002460	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00002460	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002460	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00004565	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00004565	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00004565	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00002460	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00002460	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00002460	1 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00004565	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00004565	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00004565	7 / 37
P10636	Microtubule-associated protein tau	Unclassified protein	C00004565	4 / 3
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000170	0 / 0
P07477	Trypsin-1	S1A	C00002460	1 / 1
P33527	Multidrug resistance-associated protein 1	drugs	C00004565	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00002460	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00002460	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00002460	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00004565	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00002460	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00002460	1 / 1
P07451	Carbonic anhydrase 3	Lyase	C00002460	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00002460	0 / 1
Q04760	Lactoylglutathione lyase	Enzyme	C00004565	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00004565	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00002460	0 / 0
P48147	Prolyl endopeptidase	S9A	C00004565	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002460	1 / 1
O14980	Exportin-1	Unclassified protein	C00002460	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00004565	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00004565	0 / 0
O00255	Menin	Unclassified protein	C00004565	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00004565	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002460	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002460	1 / 4
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00004565	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00004565	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00004565	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00004565	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00004565	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00004565	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00005138	0 / 3
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00004565	0 / 0

125 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
581	BAX, BCL2L4	BCL2-associated X protein	C00002460 C00004565
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00004565 C00042390
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00002460 C00004565
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002460 C00004565
2512	FTL, NBIA3	ferritin, light polypeptide	C00042390
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00004565
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00004565
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004565
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00004565
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00004565
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00004565
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00004565
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00004565
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00004565
891	CCNB1, CCNB	cyclin B1	C00004565
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00004565
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00004565
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00004565
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00004565
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00004565
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00004565
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00004565
37618			C00004565
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00004565
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00004565
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00004565
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00004565
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004565
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00004565
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00004565
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00004565
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004565
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00004565
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00004565
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00004565
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00004565
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00004565
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00004565
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00004565
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00004565
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00004565
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00004565
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00004565
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00004565
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00004565
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00004565
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00004565
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00004565
4297	KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS	lysine (K)-specific methyltransferase 2A (EC:2.1.1.43)	C00004565
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00004565
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00004565
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00004565
110357			C00004565
4502	MT2A, MT2	metallothionein 2A	C00004565
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00004565
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00004565
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00004565
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00004565
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00004565
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00004565
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00004565
5241	PGR, NR3C3, PR	progesterone receptor	C00004565
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00004565
8000	PSCA, PRO232	prostate stem cell antigen	C00004565
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00004565
6119	RPA3, REPA3	replication protein A3, 14kDa	C00004565
2810	SFN, YWHAS	stratifin	C00004565
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00004565
6773	STAT2, ISGF-3, P113, STAT113	signal transducer and activator of transcription 2, 113kDa	C00004565
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00004565
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004565
7039	TGFA, TFGA	transforming growth factor, alpha	C00004565
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00004565
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00004565
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00004565
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00004565
7161	TP73, P73	tumor protein p73	C00004565
7352	UCP3, SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	C00004565
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00004565
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00004565
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00004565
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00004565
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00004565
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00004565
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00004565
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00004565
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00042390
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00042390
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00042390
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00042390
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00042390
847	CAT	catalase (EC:1.11.1.6)	C00042390
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00042390
239	ALOX12, 12-LOX, 12S-LOX, LOG12	arachidonate 12-lipoxygenase (EC:1.13.11.31)	C00004565
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00042390
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00042390
2878	GPX3, GPx-P, GSHPx-3, GSHPx-P	glutathione peroxidase 3 (plasma) (EC:1.11.1.9)	C00042390
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00042390
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00042390
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00042390
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00042390
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00042390
7975	MAFK, NFE2U, P18	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	C00042390
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00042390
4257	MGST1, GST12, MGST, MGST-I	microsomal glutathione S-transferase 1 (EC:2.5.1.18)	C00042390
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00042390
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00042390
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00042390
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00042390
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00042390
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00042390
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00042390
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00042390
25828	TXN2, MT-TRX, MTRX, TRX2	thioredoxin 2	C00042390
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00042390
10587	TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2	thioredoxin reductase 2 (EC:1.8.1.9)	C00042390
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00042390
1546			C00002460
1553	CYP2A13, CPAD, CYP2A, CYPIIA13	cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1)	C00002460
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00002460
2158	F9, FIX, HEMB, P19, PTC, THPH8	coagulation factor IX (EC:3.4.21.22)	C00002460
3292	HSD17B1, EDH17B2, EDHB17, HSD17, SDR28C1	hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62)	C00002460
4256	MGP, MGLAP, NTI	matrix Gla protein	C00002460
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002460
79001	VKORC1, EDTP308, IMAGE3455200, MST134, MST576, VKCFD2, VKOR	vitamin K epoxide reductase complex, subunit 1 (EC:1.1.4.1)	C00002460

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