KCF-S cluster No. 2320 (5 metabolites)
Corresponding Phytochemical cluster No. 6
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 6 |
| eudicotyledons | 3 |
| Liliopsida | 2 |
| rosids | 1 |
| Magnoliophyta | 1 |
Cumulative family count
| class name | count |
|---|---|
| Lamiaceae | 4 |
| Crassulaceae | 3 |
| Amaryllidaceae | 1 |
| Lauraceae | 1 |
| Hyacinthaceae | 1 |
| Burseraceae | 1 |
| Solanaceae | 1 |
| Araliaceae | 1 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
C00002725
|
Cinnamaldehyde
|
CHEMBL293492
|
C012843
|
98 / 49 / 42 | 151 / 23 |
|
|
C00032375
|
(E)-Cinnamic alcohol
/ trans-Cinnamyl alcohol |
CHEMBL118958
CHEMBL324794 |
4 / 2 / 1 |
|
||
|
C00035187
|
(E)-Cinnamaldehyde
|
CHEMBL293492
|
98 / 49 / 42 |
|
||
|
C00037855
|
Styrene
|
CHEMBL285235
|
D020058
|
5 / 6 / 4 | 27 / 9 |
|
|
C00042390
|
Cinnamyl alcohol
|
CHEMBL118958
CHEMBL324794 |
C020722
|
4 / 2 / 1 | 32 / 1 |
|
Human Protein / Gene in interactions
102 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002725 C00032375 C00035187 C00042390 | 1 / 1 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00002725 C00032375 C00035187 C00042390 | 1 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002725 C00035187 C00037855 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002725 C00035187 C00037855 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002725 C00035187 C00037855 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002725 C00035187 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002725 C00035187 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002725 C00035187 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00002725 C00035187 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002725 C00035187 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002725 C00035187 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002725 C00035187 | 2 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002725 C00035187 | 11 / 10 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002725 C00035187 | 1 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002725 C00035187 | 1 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002725 C00035187 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002725 C00035187 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002725 C00035187 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002725 C00035187 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002725 C00035187 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002725 C00035187 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002725 C00035187 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002725 C00035187 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002725 C00035187 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002725 C00035187 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002725 C00035187 | 0 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002725 C00035187 | 1 / 8 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002725 C00035187 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002725 C00035187 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002725 C00035187 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00002725 C00035187 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002725 C00035187 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002725 C00035187 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002725 C00035187 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002725 C00035187 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002725 C00035187 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002725 C00035187 | 1 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002725 C00035187 | 2 / 1 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002725 C00035187 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002725 C00035187 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00032375 C00042390 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002725 C00035187 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002725 C00035187 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002725 C00035187 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002725 C00035187 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00002725 C00035187 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002725 C00035187 | 0 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002725 C00035187 | 0 / 1 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002725 C00035187 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002725 C00035187 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00002725 C00035187 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002725 C00035187 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002725 C00035187 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002725 C00035187 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002725 C00035187 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002725 C00035187 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002725 C00035187 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002725 C00035187 | 2 / 2 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002725 C00035187 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002725 C00035187 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002725 C00035187 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002725 C00035187 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002725 C00035187 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002725 C00035187 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002725 C00035187 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002725 C00035187 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002725 C00035187 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002725 C00035187 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002725 C00035187 | 1 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002725 C00035187 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002725 C00035187 | 2 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002725 C00035187 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002725 C00035187 | 0 / 3 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00002725 C00035187 | 0 / 0 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00032375 C00042390 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002725 C00035187 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00002725 C00035187 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002725 C00035187 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002725 C00035187 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002725 C00035187 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00002725 C00035187 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002725 C00035187 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002725 C00035187 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002725 C00035187 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002725 C00035187 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002725 C00035187 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002725 C00035187 | 0 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002725 C00035187 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002725 C00035187 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002725 C00035187 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002725 C00035187 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002725 C00035187 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002725 C00035187 | 1 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002725 C00035187 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00037855 | 3 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00037855 | 3 / 2 |
189 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00002725
C00037855
C00042390
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002725
C00037855
C00042390
|
| 3251 | HPRT1, HGPRT, HPRT | hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8) |
C00002725
C00037855
|
| 140809 | SRXN1, C20orf139, Npn3, SRX, SRX1 | sulfiredoxin 1 (EC:1.8.98.2) |
C00002725
C00042390
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002725
C00037855
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00002725
C00042390
|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00002725
C00042390
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00002725
C00037855
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00037855
C00042390
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00002725
C00042390
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00002725
C00042390
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002725
C00037855
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00002725
C00037855
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002725
C00037855
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00002725
C00042390
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00002725
C00042390
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00002725
C00042390
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00002725
C00042390
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00002725
C00037855
|
| 7273 | TTN, CMD1G, CMH9, CMPD4, EOMFC, HMERF, LGMD2J, MYLK5, TMD | titin (EC:2.7.11.1) |
C00002725
|
| 91057 | CCDC34, NY-REN-41, RAMA3 | coiled-coil domain containing 34 |
C00002725
|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00002725
|
| 29126 | CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1 | CD274 molecule |
C00002725
|
| 942 | CD86, B7-2, B7.2, B70, CD28LG2, LAB72 | CD86 molecule |
C00002725
|
| 994 | CDC25B | cell division cycle 25B (EC:3.1.3.48) |
C00002725
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002725
|
| 1066 | CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1 | carboxylesterase 1 (EC:3.1.1.1 3.1.1.56) |
C00002725
|
| 1196 | CLK2, hCLK2 | CDC-like kinase 2 (EC:2.7.12.1) |
C00002725
|
| 4848 | CNOT2, CDC36, NOT2, NOT2H | CCR4-NOT transcription complex, subunit 2 |
C00002725
|
| 1294 | COL7A1, EBD1, EBDCT, EBR1 | collagen, type VII, alpha 1 |
C00002725
|
| 1385 | CREB1, CREB | cAMP responsive element binding protein 1 |
C00002725
|
| 1390 | CREM, CREM-2, ICER, hCREM-2 | cAMP responsive element modulator |
C00002725
|
| 51232 | CRIM1, CRIM-1, S52 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
C00002725
|
| 1399 | CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
C00002725
|
| 1490 | CTGF, CCN2, HCS24, IGFBP8, NOV2 | connective tissue growth factor |
C00002725
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002725
|
| 1581 | CYP7A1, CP7A, CYP7, CYPVII | cytochrome P450, family 7, subfamily A, polypeptide 1 (EC:1.14.13.17) |
C00002725
|
| 1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00002725
|
| 54541 | DDIT4, Dig2, REDD-1, REDD1 | DNA-damage-inducible transcript 4 |
C00002725
|
| 56616 | DIABLO, DFNA64, SMAC | diablo, IAP-binding mitochondrial protein |
C00002725
|
| 2039 | DMTN, DMT, EPB49 | dematin actin binding protein |
C00002725
|
| 1789 | DNMT3B, ICF, ICF1, M.HsaIIIB | DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) |
C00002725
|
| 1848 | DUSP6, HH19, MKP3, PYST1 | dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48) |
C00002725
|
| 83658 | DYNLRB1, BITH, BLP, DNCL2A, DNLC2A, ROBLD1 | dynein, light chain, roadblock-type 1 |
C00002725
|
| 55840 | EAF2, BM040, TRAITS, U19 | ELL associated factor 2 |
C00002725
|
| 1958 | EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 | early growth response 1 |
C00002725
|
| 2034 | EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 | endothelial PAS domain protein 1 |
C00002725
|
| 2150 | F2RL1, GPR11, PAR2 | coagulation factor II (thrombin) receptor-like 1 |
C00002725
|
| 2213 | FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2 | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
C00002725
|
| 9103 | FCGR2C, CD32, CD32C, CDW32, FCG2, FCRIIC, IGFR2 | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
C00002725
|
| 2263 | FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25 | fibroblast growth factor receptor 2 (EC:2.7.10.1) |
C00002725
|
| 2330 | FMO5 | flavin containing monooxygenase 5 (EC:1.14.13.8) |
C00002725
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002725
|
| 2495 | FTH1, FHC, FTH, FTHL6, PIG15, PLIF | ferritin, heavy polypeptide 1 (EC:1.16.3.1) |
C00002725
|
| 2535 | FZD2, Fz2, fz-2, fzE2, hFz2 | frizzled family receptor 2 |
C00002725
|
| 834 | CASP1, ICE, IL1BC, P45 | caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) |
C00002725
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00002725
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00002725
|
| 2745 | GLRX, GRX, GRX1 | glutaredoxin (thioltransferase) (EC:1.8.4.1) |
C00002725
|
| 2844 | GPR21 | G protein-coupled receptor 21 |
C00002725
|
| 2877 | GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 | glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9) |
C00002725
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00002725
|
| 55973 | BCAP29, BAP29 | B-cell receptor-associated protein 29 |
C00002725
|
| 3077 | HFE, HFE1, HH, HLA-H, MVCD7, TFQTL2 | hemochromatosis |
C00002725
|
| 23250 | ATP11A, ATPIH, ATPIS | ATPase, class VI, type 11A (EC:3.6.3.1) |
C00002725
|
| 57636 | ARHGAP23 | Rho GTPase activating protein 23 |
C00002725
|
| 3304 | HSPA1B, HSP70-1B, HSP70-2 | heat shock 70kDa protein 1B |
C00002725
|
| 10553 | HTATIP2, CC3, SDR44U1, TIP30 | HIV-1 Tat interactive protein 2, 30kDa (EC:1.1.1.-) |
C00002725
|
| 27429 | HTRA2, OMI, PARK13, PRSS25 | HtrA serine peptidase 2 (EC:3.4.21.108) |
C00002725
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00002725
|
| 3429 | IFI27, FAM14D, ISG12, ISG12A, P27 | interferon, alpha-inducible protein 27 |
C00002725
|
| 10964 | IFI44L, C1orf29 | interferon-induced protein 44-like |
C00002725
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00002725
|
| 3575 | IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA | interleukin 7 receptor |
C00002725
|
| 57679 | ALS2, ALS2CR6, ALSJ, IAHSP, PLSJ | amyotrophic lateral sclerosis 2 (juvenile) |
C00002725
|
| 3638 | INSIG1, CL-6, CL6 | insulin induced gene 1 |
C00002725
|
| 22801 | ITGA11, HsT18964 | integrin, alpha 11 |
C00002725
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002725
|
| 3727 | JUND, AP-1 | jun D proto-oncogene |
C00002725
|
| 9817 | KEAP1, INrf2, KLHL19 | kelch-like ECH-associated protein 1 |
C00002725
|
| 10186 | LHFP | lipoma HMGIC fusion partner (EC:3.6.5.4) |
C00002725
|
| 29995 | LMCD1 | LIM and cysteine-rich domains 1 |
C00002725
|
| 29967 | LRP12, ST7 | low density lipoprotein receptor-related protein 12 |
C00002725
|
| 4049 | LTA, LT, TNFB, TNFSF1 | lymphotoxin alpha |
C00002725
|
| 79917 | MAGIX, JM10, PDZX | MAGI family member, X-linked |
C00002725
|
| 5605 | MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2 | mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) |
C00002725
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002725
|
| 1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00002725
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002725
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00002725
|
| 8550 | MAPKAPK5, MAPKAP-K5, MK-5, MK5, PRAK | mitogen-activated protein kinase-activated protein kinase 5 (EC:2.7.11.1) |
C00002725
|
| 57787 | MARK4, MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D | MAP/microtubule affinity-regulating kinase 4 (EC:2.7.11.1) |
C00002725
|
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00002725
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00002725
|
| 4599 | MX1, IFI-78K, IFI78, MX, MxA | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) |
C00002725
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002725
|
| 100132406 | NBPF10, AB6, AG1, NBPF9 | neuroblastoma breakpoint family, member 10 |
C00002725
|
| 653361 | NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox | neutrophil cytosolic factor 1 |
C00002725
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00002725
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002725
|
| 22981 | NINL, NLP, dJ691N24.1 | ninein-like |
C00002725
|
| 4854 | NOTCH3, CADASIL, CASIL, IMF2 | notch 3 |
C00002725
|
| 8714 | ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
C00002725
|
| 56666 | PANX2, PX2, hPANX2 | pannexin 2 |
C00002725
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002725
|
| 5140 | PDE3B, HcGIP1, cGIPDE1 | phosphodiesterase 3B, cGMP-inhibited (EC:3.1.4.17) |
C00002725
|
| 7262 | PHLDA2, BRW1C, BWR1C, HLDA2, IPL, TSSC3 | pleckstrin homology-like domain, family A, member 2 |
C00002725
|
| 8544 | PIR | pirin (iron-binding nuclear protein) (EC:1.13.11.24) |
C00002725
|
| 5366 | PMAIP1, APR, NOXA | phorbol-12-myristate-13-acetate-induced protein 1 |
C00002725
|
| 5447 | POR, CPR, CYPOR, P450R | P450 (cytochrome) oxidoreductase (EC:1.6.2.4) |
C00002725
|
| 8496 | PPFIBP1, L2, SGT2, hSGT2, hSgt2p | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
C00002725
|
| 5514 | PPP1R10, CAT53, FB19, PNUTS, PP1R10, R111, p99 | protein phosphatase 1, regulatory subunit 10 |
C00002725
|
| 11107 | PRDM5, BCS2, PFM2 | PR domain containing 5 |
C00002725
|
| 133 | ADM, AM | adrenomedullin |
C00002725
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002725
|
| 146760 | RTN4RL1, NGRH2, NgR3 | reticulon 4 receptor-like 1 |
C00002725
|
| 5054 | SERPINE1, PAI, PAI-1, PAI1, PLANH1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
C00002725
|
| 6444 | SGCD, 35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
C00002725
|
| 6563 | SLC14A1, HUT11, HsT1341, JK, RACH1, RACH2, UT-B1, UT1, UTE | solute carrier family 14 (urea transporter), member 1 |
C00002725
|
| 6506 | SLC1A2, EAAT2, GLT-1 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
C00002725
|
| 115111 | SLC26A7, SUT2 | solute carrier family 26 (anion exchanger), member 7 |
C00002725
|
| 114134 | SLC2A13, HMIT | solute carrier family 2 (facilitated glucose transporter), member 13 |
C00002725
|
| 11046 | SLC35D2, HFRC1, SQV7L, UGTrel8, hfrc | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
C00002725
|
| 23657 | SLC7A11, CCBR1, xCT | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
C00002725
|
| 6546 | SLC8A1, NCX1 | solute carrier family 8 (sodium/calcium exchanger), member 1 |
C00002725
|
| 4087 | SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2 | SMAD family member 2 |
C00002725
|
| 28966 | SNX24, PRO1284 | sorting nexin 24 |
C00002725
|
| 9295 | SRSF11, NET2, SFRS11, dJ677H15.2, p54 | serine/arginine-rich splicing factor 11 |
C00002725
|
| 132 | ADK, AK | adenosine kinase (EC:2.7.1.20) |
C00002725
|
| 27067 | STAU2, 39K2, 39K3 | staufen double-stranded RNA binding protein 2 |
C00002725
|
| 8428 | STK24, MST3, MST3B, STE20, STK3 | serine/threonine kinase 24 (EC:2.7.11.1) |
C00002725
|
| 51684 | SUFU, PRO1280, SUFUH, SUFUXL | suppressor of fused homolog (Drosophila) |
C00002725
|
| 6915 | TBXA2R, BDPLT13, TXA2-R | thromboxane A2 receptor |
C00002725
|
| 7041 | TGFB1I1, ARA55, HIC-5, HIC5, TSC-5 | transforming growth factor beta 1 induced transcript 1 |
C00002725
|
| 55258 | THNSL2, SOFAT, THS2, TSH2 | threonine synthase-like 2 (S. cerevisiae) (EC:4.2.3.-) |
C00002725
|
| 7099 | TLR4, ARMD10, CD284, TLR-4, TOLL | toll-like receptor 4 |
C00002725
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002725
|
| 27242 | TNFRSF21, BM-018, CD358, DR6 | tumor necrosis factor receptor superfamily, member 21 |
C00002725
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002725
|
| 10626 | TRIM16, EBBP | tripartite motif containing 16 |
C00002725
|
| 8989 | TRPA1, ANKTM1, FEPS | transient receptor potential cation channel, subfamily A, member 1 |
C00002725
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00002725
|
| 8745 | ADAM23, MDC-3, MDC3 | ADAM metallopeptidase domain 23 |
C00002725
|
| 7321 | UBE2D1, E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A | ubiquitin-conjugating enzyme E2D 1 (EC:6.3.2.19) |
C00002725
|
| 7360 | UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379 | UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9) |
C00002725
|
| 7374 | UNG, DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2 | uracil-DNA glycosylase (EC:3.2.2.27) |
C00002725
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00002725
|
| 340481 | ZDHHC21, 9130404H11Rik, DHHC-21, DHHC21, DNZ1, HSPC097 | zinc finger, DHHC-type containing 21 (EC:2.3.1.225) |
C00002725
|
| 79973 | ZNF442 | zinc finger protein 442 |
C00002725
|
| 440515 | ZNF506 | zinc finger protein 506 |
C00002725
|
| 51193 | ZNF639, 6230400O18Rik, ANC-2H01, ANC_2H01, ZASC1 | zinc finger protein 639 |
C00002725
|
| 231 | AKR1B1, ADR, ALDR1, ALR2, AR | aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) |
C00042390
|
| 57016 | AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI | aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) |
C00042390
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00042390
|
| 145447 | ABHD12B, BEM46L3, C14orf29, c14_5314 | abhydrolase domain containing 12B |
C00002725
|
| 2235 | FECH, EPP, FCE | ferrochelatase (EC:4.99.1.1) |
C00042390
|
| 2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00042390
|
| 2878 | GPX3, GPx-P, GSHPx-3, GSHPx-P | glutathione peroxidase 3 (plasma) (EC:1.11.1.9) |
C00042390
|
| 23764 | MAFF, U-MAF, hMafF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
C00042390
|
| 4097 | MAFG, hMAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
C00042390
|
| 7975 | MAFK, NFE2U, P18 | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
C00042390
|
| 4199 | ME1, HUMNDME, MES | malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) |
C00042390
|
| 4257 | MGST1, GST12, MGST, MGST-I | microsomal glutathione S-transferase 1 (EC:2.5.1.18) |
C00042390
|
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00042390
|
| 5226 | PGD, 6PGD | phosphogluconate dehydrogenase (EC:1.1.1.44) |
C00042390
|
| 22949 | PTGR1, LTB4DH, PGR1, ZADH3 | prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) |
C00042390
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00042390
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00042390
|
| 6649 | SOD3, EC-SOD | superoxide dismutase 3, extracellular (EC:1.15.1.1) |
C00042390
|
| 25828 | TXN2, MT-TRX, MTRX, TRX2 | thioredoxin 2 |
C00042390
|
| 10587 | TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2 | thioredoxin reductase 2 (EC:1.8.1.9) |
C00042390
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00042390
|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00037855
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00037855
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00037855
|
| 1230 | CCR1, CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 | chemokine (C-C motif) receptor 1 |
C00037855
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00037855
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00037855
|
| 2052 | EPHX1, EPHX, EPOX, HYL1, MEH | epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) |
C00037855
|
| 2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00037855
|
| 2952 | GSTT1 | glutathione S-transferase theta 1 (EC:2.5.1.18) |
C00037855
|
| 3303 | HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 | heat shock 70kDa protein 1A |
C00037855
|
| 3937 | LCP2, SLP-76, SLP76 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
C00037855
|
| 4968 | OGG1, HMMH, HOGG1, MUTM, OGH1 | 8-oxoguanine DNA glycosylase (EC:4.2.99.18) |
C00037855
|
| 5894 | RAF1, CRAF, NS5, Raf-1, c-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) |
C00037855
|
| 7042 | TGFB2, LDS4, TGF-beta2 | transforming growth factor, beta 2 |
C00037855
|
| 7049 | TGFBR3, BGCAN, betaglycan | transforming growth factor, beta receptor III |
C00037855
|
| 7515 | XRCC1, RCC | X-ray repair complementing defective repair in Chinese hamster cells 1 |
C00037855
|
| 7517 | XRCC3, CMM6 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
C00037855
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (55)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 |
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (45)
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
Diseases related to CTD interactions
32 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D017449 | Dermatitis, Allergic Contact |
C00002725
C00042390 |
| D011655 | Pulmonary Embolism |
C00002725
|
| D003110 | Colonic Neoplasms |
C00002725
|
| D003371 | Cough |
C00002725
|
| D003384 | Coxsackievirus Infections |
C00002725
|
| D006528 | Carcinoma, Hepatocellular |
C00002725
|
| D003921 | Diabetes Mellitus, Experimental |
C00002725
|
| D003924 | Diabetes Mellitus, Type 2 |
C00002725
|
| D004487 | Edema |
C00002725
|
| D004890 | Erythema |
C00002725
|
| D006470 | Hemorrhage |
C00002725
|
| D006930 | Hyperalgesia |
C00002725
|
| D006943 | Hyperglycemia |
C00002725
|
| D006984 | Hypertrophy |
C00002725
|
| D008545 | Melanoma |
C00002725
|
| D010146 | Pain |
C00002725
|
| D002471 | Cell Transformation, Neoplastic |
C00002725
|
| D012478 | Salmonella Food Poisoning |
C00002725
|
| D012481 | Salmonella Infections, Animal |
C00002725
|
| D012678 | Sensation Disorders |
C00002725
|
| D013927 | Thrombosis |
C00002725
|
| D014581 | Urticaria |
C00002725
|
| D014735 | Vibrio Infections |
C00002725
|
| D001943 | Breast Neoplasms |
C00037855
|
| D056486 | Drug-Induced Liver Injury |
C00037855
|
| D005119 | Extravasation of Diagnostic and Therapeutic Materials |
C00037855
|
| D034381 | Hearing Loss |
C00037855
|
| D055370 | Lung Injury |
C00037855
|
| D008175 | Lung Neoplasms |
C00037855
|
| D015674 | Mammary Neoplasms, Animal |
C00037855
|
| D011014 | Pneumonia |
C00037855
|
| D011041 | Poisoning |
C00037855
|