Haplopappus foliosus

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Haplopappus foliosus
Genus	Haplopappus
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Haplopappus foliosus
Linked NCBI taxonomy ID	147773
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005264	Isokaempferide 7-glucoside	CHEMBL1689265		1 / 0 / 3		No. 2	No. 15
C00005372	Hyperin / Hyperoside / Quercetin 3-O-galactoside / Quercetin 3-O-beta-D-galactoside / Quercetin 3-beta-galactopyranoside / Quercetin 3-O-beta-D-galactopyranoside	CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336	C021304	38 / 43 / 34	4 / 0	No. 2	No. 15
C00005373	Hirsutrin / Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside	CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336		38 / 43 / 34		No. 2	No. 15
C00005525	Isorhamnetin 3-glucoside / Isorhamnetin 3-O-glucoside / Isorhamnetin 3-O-beta-D-glucoside / Isorhamnetin 3-O-beta-D-glucopyranoside	CHEMBL234316 CHEMBL516621		1 / 1 / 0		No. 2	No. 15
C00005138	Astragalin / Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside	CHEMBL233930 CHEMBL453290 CHEMBL1572115	C001579	10 / 6 / 7	0 / 1	No. 2	No. 15
C00005374	Quercetin	CHEMBL82242 CHEMBL479232 CHEMBL1437696	C012526	14 / 2 / 2	2 / 1	No. 2	No. 15
C00004635	Isorhamnetin / 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL379064	C047368	12 / 10 / 13	10 / 0	No. 3	No. 15
C00004565	Kaempferol / Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL150	C006552	76 / 69 / 87	86 / 8	No. 71	No. 15
C00023486	Haplopappic acid					No. 221
C00002471	Esculetin / Aesculetin / 6,7-Dihydroxycoumarin	CHEMBL244743	C007628	40 / 44 / 32	19 / 4	No. 1030	No. 25
C00005036	Haplopappin					No. 2096
C00005037	Haplopappin A					No. 2096

Human Protein / Gene in interactions

116 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UNA4	DNA polymerase iota	Enzyme	C00002471 C00004565 C00005138 C00005372 C00005373 C00005374	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00004565 C00004635 C00005138 C00005372 C00005373 C00005374	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002471 C00004565 C00004635 C00005372 C00005373 C00005374	1 / 1
P15121	Aldose reductase	Enzyme	C00002471 C00004565 C00005138 C00005372 C00005373 C00005374	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002471 C00004635 C00005372 C00005373 C00005374	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00004565 C00004635 C00005372 C00005373 C00005374	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002471 C00004565 C00005372 C00005373 C00005374	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00004565 C00005138 C00005372 C00005373 C00005374	1 / 1
P07237	Protein disulfide-isomerase	Enzyme	C00005138 C00005372 C00005373 C00005374	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002471 C00004565 C00005372 C00005373	4 / 3
P02545	Prelamin-A/C	Unclassified protein	C00002471 C00004565 C00005372 C00005373	11 / 10
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002471 C00005372 C00005373 C00005374	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00004565 C00005264 C00005372 C00005373	0 / 3
P14679	Tyrosinase	Oxidoreductase	C00004565 C00005138 C00005372 C00005373	4 / 2
P04062	Glucosylceramidase	Enzyme	C00002471 C00004565 C00005372 C00005373	6 / 4
O75164	Lysine-specific demethylase 4A	Enzyme	C00002471 C00004565 C00005374	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002471 C00005372 C00005373	1 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004565 C00005372 C00005373	2 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002471 C00004565 C00004635	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002471 C00005372 C00005373	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00002471 C00004565 C00005138	1 / 1
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00005372 C00005373 C00005525	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002471 C00005372 C00005373	4 / 1
Q9NPH5	NADPH oxidase 4	Enzyme	C00004565 C00005372 C00005373	0 / 0
O75496	Geminin	Unclassified protein	C00002471 C00005372 C00005373	0 / 0
P34949	Mannose-6-phosphate isomerase	Enzyme	C00002471 C00005372 C00005373	1 / 1
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00004565 C00005372 C00005373	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002471 C00004565 C00005374	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002471 C00005372 C00005373	1 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002471 C00005372 C00005373	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002471 C00004565	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002471 C00004565	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00005372 C00005373	1 / 4
Q13951	Core-binding factor subunit beta	Unclassified protein	C00005372 C00005373	0 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00004565 C00004635	1 / 2
O00255	Menin	Unclassified protein	C00004565 C00004635	2 / 5
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005372 C00005373	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002471 C00004565	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00005372 C00005373	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00004565 C00004635	0 / 0
P06746	DNA polymerase beta	Enzyme	C00005372 C00005373	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002471 C00004565	0 / 1
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00004565 C00004635	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002471 C00004565	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002471 C00004565	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002471 C00004565	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00005372 C00005373	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00005372 C00005373	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005372 C00005373	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002471 C00004565	2 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002471 C00004565	3 / 3
P10696	Alkaline phosphatase, placental-like	Enzyme	C00005372 C00005373	0 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00005372 C00005373	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00005372 C00005373	3 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00005372 C00005373	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00004565 C00004635	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00004565 C00004635	4 / 4
Q04760	Lactoylglutathione lyase	Enzyme	C00004565	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00004565	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00004565	5 / 3
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00004565	0 / 0
P06276	Cholinesterase	Hydrolase	C00004565	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005138	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002471	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00004565	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00005374	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00004565	0 / 0
P56817	Beta-secretase 1	A1A	C00002471	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00004565	0 / 0
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00004565	1 / 1
P29466	Caspase-1	C14	C00002471	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00004565	0 / 1
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00004565	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00005138	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002471	0 / 0
P03372	Estrogen receptor	NR3A1	C00004565	1 / 1
P22303	Acetylcholinesterase	Hydrolase	C00004565	1 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002471	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002471	0 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00004565	1 / 0
P55210	Caspase-7	C14	C00002471	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00004565	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00004565	0 / 0
P08183	Multidrug resistance protein 1	drug	C00004565	1 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00004565	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00004565	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00004565	2 / 2
Q9Y3R4	Sialidase-2	Enzyme	C00004565	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002471	5 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002471	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00004565	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00004565	0 / 0
P10275	Androgen receptor	NR3C4	C00004565	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00004565	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00004565	0 / 1
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00004565	0 / 0
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00005374	0 / 0
P48147	Prolyl endopeptidase	S9A	C00004565	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00004565	7 / 37
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002471	3 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00004565	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00004565	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002471	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00004565	1 / 8
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00004565	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00004565	0 / 0
P04792	Heat shock protein beta-1	Unclassified protein	C00004635	2 / 1
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00004565	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00004565	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00004565	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00004565	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00004565	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00004565	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00004565	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00005138	0 / 3
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00004565	0 / 0

100 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002471 C00004565 C00005372
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00004565 C00004635 C00005374
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00004565 C00004635 C00005374
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00004565 C00004635 C00005372
581	BAX, BCL2L4	BCL2-associated X protein	C00002471 C00004565 C00005372
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002471 C00004565
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002471 C00004565
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004565 C00004635
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002471 C00004565
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004565 C00004635
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00002471 C00004565
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002471 C00004565
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002471 C00004565
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004565 C00004635
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00004565 C00004635
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004565 C00004635
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00004565
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00004565
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00004565
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00004565
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00004565
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00004565
37618			C00004565
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00004565
891	CCNB1, CCNB	cyclin B1	C00004565
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00004565
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00004565
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00004565
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00004565
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00004565
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00004565
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00004565
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00004565
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00004565
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00004565
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00004565
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00004565
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00004565
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00004565
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00004565
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00004565
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00004565
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00004565
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00004565
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00004565
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00004565
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00004565
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00004565
4297	KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS	lysine (K)-specific methyltransferase 2A (EC:2.1.1.43)	C00004565
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00004565
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00004565
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00004565
110357			C00004565
4502	MT2A, MT2	metallothionein 2A	C00004565
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00004565
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00004565
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00004565
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00004565
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00004565
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00004565
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00004565
5241	PGR, NR3C3, PR	progesterone receptor	C00004565
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00004565
8000	PSCA, PRO232	prostate stem cell antigen	C00004565
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00004565
6119	RPA3, REPA3	replication protein A3, 14kDa	C00004565
2810	SFN, YWHAS	stratifin	C00004565
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00004565
6773	STAT2, ISGF-3, P113, STAT113	signal transducer and activator of transcription 2, 113kDa	C00004565
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00004565
239	ALOX12, 12-LOX, 12S-LOX, LOG12	arachidonate 12-lipoxygenase (EC:1.13.11.31)	C00004565
7039	TGFA, TFGA	transforming growth factor, alpha	C00004565
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00004565
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00004565
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00004565
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00004565
7161	TP73, P73	tumor protein p73	C00004565
7352	UCP3, SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	C00004565
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00004565
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00004565
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00004565
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00004565
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00004565
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00004565
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00004565
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00004565
637	BID, FP497	BH3 interacting domain death agonist	C00002471
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002471
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00002471
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00002471
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002471
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00002471
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002471
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002471
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002471
8797	TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1	tumor necrosis factor receptor superfamily, member 10a	C00002471
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002471
23411	SIRT1, SIR2L1	sirtuin 1	C00005372
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00004635
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00004635

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