Diospyros kaki

• Index
• Plant Species
• Metabolite list (38)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Diospyros kaki
Genus	Diospyros
Family	Ebenaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Diospyros kaki
Linked NCBI taxonomy ID	35925
Linked level	species

Family

Family in NCBI taxonomy	Ebenaceae
ID	19955

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (38)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005138	Astragalin / Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside	CHEMBL233930 CHEMBL453290 CHEMBL1572115	C001579	10 / 6 / 7	0 / 1	No. 2	No. 15
C00009020	Leucodelphinidin 3-glucoside					No. 12	No. 14
C00036107	Coussaric acid	CHEMBL492458		1 / 0 / 0		No. 13	No. 51
C00031074	Pomolic acid	CHEMBL486986 CHEMBL464567		2 / 0 / 0		No. 13	No. 51
C00029789	Barbinervic acid	CHEMBL523209 CHEMBL493908 CHEMBL1271052	C052363	2 / 0 / 0		No. 13	No. 51
C00019064	Oleanolic acid / Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid	CHEMBL56615 CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454	D009828	30 / 8 / 12	21 / 15	No. 13	No. 51
C00031228	Rotungenic acid / (+)-Rotungenic acid	CHEMBL523209 CHEMBL493908 CHEMBL1271052		2 / 0 / 0		No. 13	No. 51
C00032467	Uvaol / Uvalol / Urs-12-ene-3beta,28-diol / 3beta,28-Dihydroxyurs-12-ene	CHEMBL58872 CHEMBL399873	C013330	5 / 2 / 2		No. 13	No. 51
C00003758	Alnulin / Tiliadin / Skimmiol / Taraxerol	CHEMBL511822 CHEMBL470462	C005802			No. 13	No. 51
C00040339	Spathodic acid	CHEMBL493893		1 / 0 / 0		No. 13	No. 51
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00003737	alpha-Amyrin / alpha-Amyrine / alpha-Amyrenol					No. 23	No. 51
C00003740	Betulin	CHEMBL23236 CHEMBL140040 CHEMBL1610940 CHEMBL2000891 CHEMBL2069124	C002503	18 / 16 / 17	0 / 2	No. 23	No. 51
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51
C00003765	alpha-Carotene					No. 26	No. 59
C00000919	beta-Carotene	CHEMBL1293 CHEMBL1966639	D019207	7 / 12 / 11	104 / 19	No. 26	No. 59
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00023774	Fucostanol / Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol	CHEMBL66943 CHEMBL186373 CHEMBL400247 CHEMBL1568947	D013265	5 / 0 / 0	1 / 0	No. 53	No. 11
C00003647	Campesterol / 24alpha-Methylcholesterol / (24R)24-Methylcholest-5-en-3beta-ol	CHEMBL520535 CHEMBL485421 CHEMBL1836653	C021273			No. 53	No. 11
C00000911	Lycopene / all-trans-Lycopene	CHEMBL501174 CHEMBL1984187	C015329	6 / 13 / 13	84 / 13	No. 97	No. 59
C00005957	Quercetin 3-(2''-galloylglucoside)	CHEMBL459260 CHEMBL505880				No. 98
C00005846	Kaempferol 3-(2''-galloylglucoside)	CHEMBL444191				No. 98
C00000926	gamma-Carotene					No. 131	No. 59
C00029633	Ursolic acid / Acetylursolic acid	CHEMBL55086 CHEMBL410525		4 / 2 / 2		No. 177
C00002831	Isodiospyrin	CHEMBL1992900	C409666			No. 312
C00033160	Maritinone / 8,8'-Biplumbagin	CHEMBL512154	C079947			No. 312
C00002816	Euclein / Diospyrin	CHEMBL242550	C043546			No. 312
C00043762	Neodiospyrin	CHEMBL241392				No. 312
C00043693	Mamegakinone					No. 312
C00000107	IAN / Indole-3-acetonitrile	CHEMBL1812654	C016516			No. 710	No. 4
C00000332	Methyl pheophorbide a	CHEMBL408290 CHEMBL504821 CHEMBL1985396	C032625			No. 990
C00000323	Methyl pheophorbide b					No. 990
C00002852	Plumbagin / Plumbagine	CHEMBL295316	C014758	28 / 30 / 59	14 / 3	No. 1047	No. 80
C00000100	IAA / Indole-3-acetic acid	CHEMBL82411	C030737	3 / 0 / 0	2 / 1	No. 1432	No. 4
C00043916	Shinanolone	CHEMBL391802 CHEMBL459915				No. 1520
C00043192	3-Methoxy-7-methyljuglone	CHEMBL449429				No. 3269
C00000101	IAA methyl ester / Methyl indole-3-acetate					No. 4225
C00002859	Ramentaceone / 7-Methyljuglone	CHEMBL430853				No. 4286	No. 80

Human Protein / Gene in interactions

101 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672 C00003740 C00019064 C00029789 C00031074 C00031228 C00032467 C00036107 C00040339	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003672 C00003741 C00019064 C00023774 C00029633	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000911 C00000919 C00003740 C00003741	11 / 10
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002852 C00005138 C00019064 C00029633	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002852 C00003672 C00003740 C00003741	0 / 1
P11387	DNA topoisomerase 1	Isomerase	C00002852 C00003740 C00003741 C00003749	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003740 C00003741 C00003749 C00023774	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003740 C00003741 C00019064 C00032467	0 / 0
O75496	Geminin	Unclassified protein	C00000911 C00000919 C00003741 C00019064	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003740 C00003741 C00019064 C00032467	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00003741 C00019064	0 / 0
P15121	Aldose reductase	Enzyme	C00003741 C00005138 C00019064	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003672 C00003740 C00003741	0 / 1
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000919 C00002852 C00019064	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003672 C00003740 C00003741	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003672 C00003740 C00003741	1 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003740 C00003741 C00019064	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003672 C00003740 C00003741	1 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00003749 C00031074	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000911 C00002852 C00003741	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741 C00029789 C00031228	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000911 C00002852 C00003740	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00003740 C00003741	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002852 C00003672	1 / 1
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002852 C00029633	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672 C00032467	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00005138 C00019064	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003740 C00003741	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00005138 C00019064	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672 C00003741	2 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00003741 C00019064	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672 C00005138	4 / 2
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00019064 C00029633	2 / 2
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00003740 C00019064	0 / 3
P11473	Vitamin D3 receptor	NR1I1	C00000911 C00002852	2 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00003741 C00005138	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00000919 C00002852	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00002852 C00003741	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003740 C00003741	0 / 0
P04054	Phospholipase A2	Enzyme	C00019064	0 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
P29466	Caspase-1	C14	C00002852	0 / 0
Q16773	Kynurenine--oxoglutarate transaminase 1	Enzyme	C00000100	0 / 0
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00019064	4 / 2
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003741	0 / 0
P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	Enzyme	C00032467	1 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00019064	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00019064	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002852	0 / 0
P24666	Low molecular weight phosphotyrosine protein phosphatase	Tyr	C00019064	0 / 0
P00734	Prothrombin	S1A	C00003672	4 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
P54132	Bloom syndrome protein	Enzyme	C00002852	1 / 2
Q9HBH1	Peptide deformylase, mitochondrial	Enzyme	C00000100	0 / 0
Q99558	Mitogen-activated protein kinase kinase kinase 14	Unique STE serine/threonine protein kinase	C00002852	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00019064	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002852	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005138	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002852	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002852	2 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00003740	3 / 1
P03372	Estrogen receptor	NR3A1	C00003672	1 / 1
P09884	DNA polymerase alpha catalytic subunit	Transferase	C00023774	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003741	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00023774	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002852	0 / 0
P55210	Caspase-7	C14	C00002852	0 / 0
P35228	Nitric oxide synthase, inducible	Enzyme	C00019064	1 / 1
Q99700	Ataxin-2	Unclassified protein	C00005138	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00002852	4 / 1
P10586	Receptor-type tyrosine-protein phosphatase F	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002852	7 / 37
P10636	Microtubule-associated protein tau	Unclassified protein	C00002852	4 / 3
P17706	Tyrosine-protein phosphatase non-receptor type 2	Tyr	C00019064	0 / 1
P04049	RAF proto-oncogene serine/threonine-protein kinase	Raf	C00002852	2 / 0
P29350	Tyrosine-protein phosphatase non-receptor type 6	Tyr	C00019064	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005138	0 / 0
P08183	Multidrug resistance protein 1	drug	C00003672	1 / 0
P23469	Receptor-type tyrosine-protein phosphatase epsilon	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
Q02750	Dual specificity mitogen-activated protein kinase kinase 1	Ste7	C00002852	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002852	0 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00019064	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000911	0 / 0
P02768	Serum albumin	Secreted protein	C00000100	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
O00255	Menin	Unclassified protein	C00002852	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002852	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00019064	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00019064	1 / 4
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000919	0 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000919	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000919	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00023774	0 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00005138	0 / 3

205 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000911 C00000919 C00002852 C00003741 C00019064
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000919 C00002852 C00003741 C00019064
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000919 C00003741 C00019064
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000911 C00000919 C00019064
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000911 C00000919 C00019064
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000911 C00002852 C00003741
3713	IVL	involucrin	C00000911 C00000919
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000911 C00019064
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741 C00019064
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741 C00019064
4842	NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS	nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)	C00000911 C00000919
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749 C00019064
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00000911 C00019064
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000911 C00019064
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00000911 C00019064
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002852 C00019064
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000911 C00000919
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000911 C00000919
581	BAX, BCL2L4	BCL2-associated X protein	C00000919 C00003741
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000911 C00019064
847	CAT	catalase (EC:1.11.1.6)	C00000911 C00019064
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000911 C00019064
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000100 C00000911
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00000911 C00019064
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00000919
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002852
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00000911
571	BACH1, BACH-1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	C00000911
8314	BAP1, HUCEP-13, UCHL2	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (EC:3.4.19.12)	C00000911
673	BRAF, B-RAF1, BRAF1, NS7, RAFB1	v-raf murine sarcoma viral oncogene homolog B (EC:2.7.11.1)	C00000911
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002852
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002852
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002852
898	CCNE1, CCNE	cyclin E1	C00000911
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00000911
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000911
1020	CDK5, PSSALRE	cyclin-dependent kinase 5 (EC:2.7.11.22)	C00000911
1022	CDK7, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15	cyclin-dependent kinase 7 (EC:2.7.11.23 2.7.11.22)	C00000911
1025	CDK9, C-2k, CDC2L4, CTK1, PITALRE, TAK	cyclin-dependent kinase 9 (EC:2.7.11.23 2.7.11.22)	C00000911
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000911
1113	CHGA, CGA	chromogranin A (parathyroid secretory protein 1)	C00000911
1114	CHGB, SCG1	chromogranin B (secretogranin 1)	C00000911
23418	CRB1, LCA8, RP12	crumbs homolog 1 (Drosophila)	C00000911
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002852
1643	DDB2, DDBB, UV-DDB2	damage-specific DNA binding protein 2, 48kDa	C00000911
1981	EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18	eukaryotic translation initiation factor 4 gamma, 1	C00000911
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00002852
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002852
2176	FANCC, FA3, FAC, FACC	Fanconi anemia, complementation group C	C00000911
2188	FANCF, FAF	Fanconi anemia, complementation group F	C00000911
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00000911
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00000911
2701	GJA4, CX37	gap junction protein, alpha 4, 37kDa	C00000911
2702	GJA5, ATFB11, CX40	gap junction protein, alpha 5, 40kDa	C00000911
2879	GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx	glutathione peroxidase 4 (EC:1.11.1.12)	C00000911
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002852
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00002852
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00000911
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00000911
3485	IGFBP2, IBP2, IGF-BP53	insulin-like growth factor binding protein 2, 36kDa	C00000911
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00002852
3716	JAK1, JAK1A, JAK1B, JTK3	Janus kinase 1 (EC:2.7.10.2)	C00000911
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000911
3796	KIF2A, CDCBM3, HK2, KIF2	kinesin heavy chain member 2A	C00000911
3838	KPNA2, IPOA1, QIP2, RCH1, SRP1alpha	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	C00000911
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00000911
3988	LIPA, CESD, LAL	lipase A, lysosomal acid, cholesterol esterase (EC:3.1.1.13)	C00000911
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00000911
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00000911
6416	MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1	mitogen-activated protein kinase kinase 4 (EC:2.7.12.2)	C00000911
5608	MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3	mitogen-activated protein kinase kinase 6 (EC:2.7.12.2)	C00000911
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00000911
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000911
4247	MGAT2, CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143)	C00000911
100507436	MICA, MIC-A, PERB11.1	MHC class I polypeptide-related sequence A	C00000911
4292	MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1	mutL homolog 1	C00000911
4436	MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2	mutS homolog 2	C00000911
2956	MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160	mutS homolog 6	C00000911
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
8021	NUP214, CAIN, CAN, D9S46E, N214, p250	nucleoporin 214kDa	C00000911
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00000911
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00000911
10111	RAD50, NBSLD, RAD502, hRad50	RAD50 homolog (S. cerevisiae)	C00000911
8045	RASSF7, C11orf13, HRAS1, HRC1	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	C00000911
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000911
5962	RDX, DFNB24	radixin	C00000911
6195	RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)	C00000911
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00000911
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00000911
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741
6414	SEPP1, SELP, SeP	selenoprotein P, plasma, 1	C00000911
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00000911
8243	SMC1A, CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB	structural maintenance of chromosomes 1A	C00000911
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00000911
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00000911
7980	TFPI2, PP5, REF1, TFPI-2	tissue factor pathway inhibitor 2	C00000911
7039	TGFA, TFGA	transforming growth factor, alpha	C00000911
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00000911
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00000911
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003741
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000911
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
7415	VCP, ALS14, IBMPFD, IBMPFD1, TERA, p97	valosin containing protein (EC:3.6.4.6)	C00000911
7485	WRB, CHD5	tryptophan rich basic protein	C00000911
7697	ZNF138, pHZ-32	zinc finger protein 138	C00000911
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00000100
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00019064
3065	HDAC1, GON-10, HD1, RPD3, RPD3L1	histone deacetylase 1 (EC:3.5.1.98)	C00019064
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00019064
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019064
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00023774
124	ADH1A, ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1)	C00000919
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00000919
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00000919
8659	ALDH4A1, ALDH4, P5CD, P5CDh	aldehyde dehydrogenase 4 family, member A1 (EC:1.2.1.88)	C00000919
287	ANK2, ANK-2, LQT4, brank-2	ankyrin 2, neuronal	C00000919
288	ANK3, ANKYRIN-G, MRT37	ankyrin 3, node of Ranvier (ankyrin G)	C00000919
427	ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME	N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)	C00000919
51665	ASB1, ASB-1	ankyrin repeat and SOCS box containing 1	C00000919
140462	ASB9	ankyrin repeat and SOCS box containing 9	C00000919
9531	BAG3, BAG-3, BIS, CAIR-1, MFM6	BCL2-associated athanogene 3	C00000919
9530	BAG4, BAG-4, SODD	BCL2-associated athanogene 4	C00000919
9529	BAG5, BAG-5	BCL2-associated athanogene 5	C00000919
53630	BCMO1, BCDO, BCDO1, BCMO, BCO, BCO1	beta-carotene 15,15'-monooxygenase 1 (EC:1.14.99.36)	C00000919
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00000919
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00000919
9071	CLDN10, CPETRL3, OSP-L	claudin 10	C00000919
51208	CLDN18, SFTA5, SFTPJ	claudin 18	C00000919
1277	COL1A1, OI4	collagen, type I, alpha 1	C00000919
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00000919
1284	COL4A2, ICH, POREN2	collagen, type IV, alpha 2	C00000919
8738	CRADD, MRT34, RAIDD	CASP2 and RIPK1 domain containing adaptor with death domain	C00000919
1508	CTSB, APPS, CPSB	cathepsin B (EC:3.4.22.1)	C00000919
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00000919
6372	CXCL6, CKA-3, GCP-2, GCP2, SCYB6	chemokine (C-X-C motif) ligand 6	C00000919
4283	CXCL9, CMK, Humig, MIG, SCYB9, crg-10	chemokine (C-X-C motif) ligand 9	C00000919
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00000919
1592	CYP26A1, CP26, CYP26, P450RAI, P450RAI1	cytochrome P450, family 26, subfamily A, polypeptide 1 (EC:1.14.-.-)	C00000919
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000919
64816	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43 (EC:1.14.14.1)	C00000919
1746	DLX2, TES-1, TES1	distal-less homeobox 2	C00000919
1748	DLX4, BP1, DLX7, DLX8, DLX9	distal-less homeobox 4	C00000919
2068	ERCC2, COFS2, EM9, TTD, XPD	excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12)	C00000919
23017	FAIM2, LFG, LFG2, NGP35, NMP35, TMBIM2	Fas apoptotic inhibitory molecule 2	C00000919
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00000919
3169	FOXA1, HNF3A, TCF3A	forkhead box A1	C00000919
2627	GATA6	GATA binding protein 6	C00000919
2633	GBP1	guanylate binding protein 1, interferon-inducible	C00000919
81025	GJA9, CX58, CX59, GJA10	gap junction protein, alpha 9, 59kDa	C00000919
373156	GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1	glutathione S-transferase kappa 1 (EC:2.5.1.18)	C00000919
2946	GSTM2, GST4, GSTM, GSTM2-2, GTHMUS	glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18)	C00000919
2948	GSTM4, GSTM4-4, GTM4	glutathione S-transferase mu 4 (EC:2.5.1.18)	C00000919
2949	GSTM5, GSTM5-5, GTM5	glutathione S-transferase mu 5 (EC:2.5.1.18)	C00000919
2954	GSTZ1, GSTZ1-1, MAAI, MAI	glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2)	C00000919
3204	HOXA7, ANTP, HOX1, HOX1.1, HOX1A	homeobox A7	C00000919
3216	HOXB6, HOX2, HOX2B, HU-2, Hox-2.2	homeobox B6	C00000919
3226	HOXC10, HOX3I	homeobox C10	C00000919
3448	IFNA14, IFN-alphaH, LEIF2H	interferon, alpha 14	C00000919
3449	IFNA16, IFN-alphaO	interferon, alpha 16	C00000919
3451	IFNA17, IFN-alphaI, IFNA, INFA, LEIF2C1	interferon, alpha 17	C00000919
3442	IFNA5, IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF_G	interferon, alpha 5	C00000919
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000919
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000919
3394	IRF8, H-ICSBP, ICSBP, ICSBP1, IRF-8	interferon regulatory factor 8	C00000919
50805	IRX4, IRXA3	iroquois homeobox 4	C00000919
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00000919
3691	ITGB4, CD104	integrin, beta 4	C00000919
3875	KRT18, CYK18, K18	keratin 18	C00000919
3880	KRT19, CK19, K19, K1CS	keratin 19	C00000919
3849	KRT2, CK-2e, K2e, KRT2A, KRT2E, KRTE	keratin 2	C00000919
3855	KRT7, CK7, K2C7, K7, SCL	keratin 7	C00000919
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00000919
8022	LHX3, CPHD3, LIM3, M2-LHX3	LIM homeobox 3	C00000919
4153	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD	mannose-binding lectin (protein C) 2, soluble	C00000919
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00000919
4212	MEIS2, HsT18361, MRG1	Meis homeobox 2	C00000919
4222	MEOX1, KFS2, MOX1	mesenchyme homeobox 1	C00000919
118	ADD1, ADDA	adducin 1 (alpha)	C00000911
3110	MNX1, HB9, HLXB9, HOXHB9, SCRA1	motor neuron and pancreas homeobox 1	C00000919
4439	MSH5, G7, MUTSH5, NG23	mutS homolog 5	C00000919
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00000919
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000919
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00000919
5098	PCDHGC3, PC43, PCDH-GAMMA-C3, PCDH2	protocadherin gamma subfamily C, 3	C00000919
5359	PLSCR1, MMTRA1B	phospholipid scramblase 1	C00000919
57048	PLSCR3	phospholipid scramblase 3	C00000919
57088	PLSCR4, TRA1	phospholipid scramblase 4	C00000919
10635	RAD51AP1, PIR51	RAD51 associated protein 1	C00000919
5892	RAD51D, BROVCA4, R51H3, RAD51L3, TRAD	RAD51 paralog D	C00000919
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00000919
5915	RARB, HAP, NR1B2, RRB2	retinoic acid receptor, beta	C00000919
5918	RARRES1, LXNL, TIG1	retinoic acid receptor responder (tazarotene induced) 1	C00000919
5950	RBP4, RDCCAS	retinol binding protein 4, plasma	C00000919
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00000919
949	SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1	scavenger receptor class B, member 1	C00000919
4990	SIX6, MCOPCT2, OPTX2, Six9	SIX homeobox 6	C00000919
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000919
9517	SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a	serine palmitoyltransferase, long chain base subunit 2 (EC:2.3.1.50)	C00000919
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00000919
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00000919
7047	TGM4, TGP, hTGP	transglutaminase 4 (EC:2.3.2.13)	C00000919
3604	TNFRSF9, 4-1BB, CD137, CDw137, ILA	tumor necrosis factor receptor superfamily, member 9	C00000919
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00000919
10190	TXNDC9, APACD, PHLP3	thioredoxin domain containing 9	C00000919
7517	XRCC3, CMM6	X-ray repair complementing defective repair in Chinese hamster cells 3	C00000919

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