Species

KNApSAcK Entry

Organism name Phlomis spectabilis
Genus Phlomis
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Phlomis
Linked NCBI taxonomy ID 316257
Linked level genus

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005138 External link 512 Astragalin
/ Kaempferol 3-glucoside
/ Kaempferol 3-O-beta-D-glucoside
/ Kaempferol 3-O-beta-D-glucopyranoside
CHEMBL233930
CHEMBL453290
CHEMBL1572115
C001579
10 / 6 / 7 0 / 1 No. 2 No. 15
C00005287 External link 512 Kaempferide 3-glucoside
/ Kaempferide 3-O-beta-D-glucopyranoside
No. 2 No. 15
C00005851 External link 512 Tiliroside
/ Potengriffioside A
/ Kaempferol 3-O-beta-D-(6''-coumaroyl)-glucopyranoside
CHEMBL266564
CHEMBL499705
C052083
2 / 1 / 2 No. 30 No. 15
C00005933 External link 512 Kaempferol 7,4'-dimethyl ether 3-(6''-(E)-p-coumarylglucoside)
No. 30 No. 15

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00005138 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005138 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005851 1 / 1
P07237 Protein disulfide-isomerase Enzyme C00005138 0 / 0
P15121 Aldose reductase Enzyme C00005138 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005138 1 / 1
P14679 Tyrosinase Oxidoreductase C00005138 4 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005138 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005851 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00005138 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005138 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00005138 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (9)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00036 Osteosarcoma P08684 (marker)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00192 Xanthinuria P47989 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003876 Dermatitis, Atopic C00005138