Phlomis spinidens

• Index
• Plant Species
• Metabolite list (13)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Phlomis spinidens
Genus	Phlomis
Family	Labiatae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Phlomis
Linked NCBI taxonomy ID	316257
Linked level	genus

Family

Family in NCBI taxonomy	Lamiaceae
ID	4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (13)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00033294	Phlomisflavoside B / (-)-Phlomisflavoside B					No. 1	No. 15
C00033293	Phlomisflavoside A / (-)-Phlomisflavoside A					No. 1	No. 15
C00005373	Hirsutrin / Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside	CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336		38 / 43 / 34		No. 2	No. 15
C00005138	Astragalin / Kaempferol 3-glucoside / Kaempferol 3-O-beta-D-glucoside / Kaempferol 3-O-beta-D-glucopyranoside	CHEMBL233930 CHEMBL453290 CHEMBL1572115	C001579	10 / 6 / 7	0 / 1	No. 2	No. 15
C00030317	Forsythoside B	CHEMBL393292		1 / 0 / 3		No. 33
C00031274	Salidroside / Rhodioloside / (-)-Rhodioloside / Tyrosol alpha-(beta-D-glucopyranoside)	CHEMBL465208 CHEMBL1899113	C009172	3 / 0 / 0		No. 45	No. 72
C00010690	Barlerin / (-)-Barlerin / 8-O-Acetylshanzhiside methyl ester	CHEMBL463751 CHEMBL463377	C099473			No. 56	No. 36
C00033295	Phlomoside A / (-)-Phlomoside A					No. 56	No. 36
C00010687	Shanzhiside methyl ester	CHEMBL1081414		1 / 1 / 1		No. 56	No. 36
C00010589	Lamalbid / Lamalbide / Lamiridoside	CHEMBL1079619 CHEMBL2048642				No. 56	No. 36
C00033296	Phlorigidoside C / (-)-Phlorigidoside C	CHEMBL2048531				No. 56	No. 36
C00029980	Citroside A / (-)-Citroside A	CHEMBL1814429				No. 316
C00000602	(+)-Lariciresinol	CHEMBL518421		2 / 1 / 1		No. 700	No. 21

Human Protein / Gene in interactions

47 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9Y253	DNA polymerase eta	Enzyme	C00005138 C00005373	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00005138 C00005373	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00005138 C00005373	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00005138 C00005373	4 / 2
P15121	Aldose reductase	Enzyme	C00005138 C00005373	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00005373 C00030317	0 / 3
O75496	Geminin	Unclassified protein	C00005373 C00031274	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005138 C00005373	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000602	1 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005138	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00005373	11 / 10
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00005373	1 / 1
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005373	0 / 0
P04062	Glucosylceramidase	Enzyme	C00005373	6 / 4
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00005373	1 / 0
P60033	CD81 antigen	Unclassified protein	C00010687	1 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00031274	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00005373	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00005373	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00005373	0 / 0
P06746	DNA polymerase beta	Enzyme	C00005373	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00005373	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00005138	1 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00005373	1 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00005373	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00005373	3 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00031274	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005373	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00005373	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00005373	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00005373	0 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00005373	2 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00005138	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00005373	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000602	0 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00005373	4 / 1
Q9NPH5	NADPH oxidase 4	Enzyme	C00005373	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00005373	4 / 3
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00005373	1 / 0
P34949	Mannose-6-phosphate isomerase	Enzyme	C00005373	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00005373	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00005373	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00005373	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00005373	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00005373	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00005373	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00005138	0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions