KCF-S cluster No. 33 (105 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (105)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	289
rosids	5
Magnoliophyta	1

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Cumulative family count

class name	count
Plantaginaceae	79
Lamiaceae	53
Oleaceae	42
Bignoniaceae	37
Scrophulariaceae	18
Verbenaceae	18
Acanthaceae	17
Gesneriaceae	9
Orobanchaceae	7
Asteraceae	5
Malvaceae	3
Magnoliaceae	1
Celastraceae	1
Fabaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (105)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002726	4'-Cinnamoylmussatioside		C064379
C00002738	Echinacoside	CHEMBL393090 CHEMBL510539	C060297	6 / 3 / 4	3 / 1
C00002744	Forsythiaside / Forsythoside A	CHEMBL504363	C058049	1 / 0 / 0
C00002750	Hellicoside
C00002754	Jionoside B1	CHEMBL233094
C00002761	Myricoside
C00002763	Orobanchoside
C00002767	Plantamajoside		C421173
C00002769	Purpureaside C	CHEMBL393090 CHEMBL510539		6 / 3 / 4
C00002781	Suspensaside		C037876
C00002783	Kusaginin / Acteoside / Verbascoside	CHEMBL231853 CHEMBL444478 CHEMBL1364101	C058956	12 / 1 / 1	34 / 3
C00024144	Scroside A
C00024145	Scroside B
C00024146	Scroside C
C00029848	Brandioside		C070029
C00030155	Dolichandroside / (-)-Dolichandroside
C00030317	Forsythoside B	CHEMBL393292		1 / 0 / 3
C00030516	Isoacteoside / Isoverbascoside	CHEMBL504873	C064683	6 / 5 / 4
C00030623	Lamiuside A / (-)-Lamiuside A
C00030624	Lamiuside B / (-)-Lamiuside B
C00030625	Lamiuside C
C00030626	Lamiuside D / (-)-Lamiuside D
C00030627	Lamiuside E	CHEMBL233094
C00030657	Leucosceptoside A	CHEMBL450121		1 / 0 / 0
C00030695	Luteoside B / Newbouldioside	CHEMBL450497
C00030993	Phlinoside C		C064692
C00031052	Plantainoside D / (+)-Plantainoside D	CHEMBL452413		1 / 0 / 0
C00031070	Poliumoside	CHEMBL499145		1 / 0 / 0
C00031192	Rossicaside A	CHEMBL459779
C00031193	Rossicaside B
C00031194	Rossicaside E
C00031325	Scroside D / (-)-Scroside D
C00031760	Ehrenoside
C00031850	Hemiphroside A
C00032921	Dracunculifoside H / (-)-Dracunculifoside H
C00032922	Dracunculifoside I / (-)-Dracunculifoside I
C00032927	Dracunculifoside N / (-)-Dracunculifoside N
C00032928	Dracunculifoside O / (-)-Dracunculifoside O
C00033467	Verpectoside A / (-)-Verpectoside A
C00033468	Verpectoside B / (+)-Verpectoside B
C00033469	Verpectoside C / (+)-Verpectoside C
C00033613	Aeschynanthoside A / (-)-Aeschynanthoside A
C00033614	Aeschynanthoside B / (-)-Aeschynanthoside B
C00033615	Aeschynanthoside C / (-)-Aeschynanthoside C
C00033616	Aeschynanthoside D / (-)-Aeschynanthoside D
C00033687	Calceolarioside E
C00033958	Isonuomioside A
C00034095	Oxoverbascoside
C00034553	Isomartynoside
C00034563	Jionoside D	CHEMBL555710
C00034577	Leucosceptoside B
C00034597	Martynoside	CHEMBL234764 CHEMBL503531 CHEMBL2134071		1 / 7 / 3
C00034734	Turrillioside A
C00034798	Arenarioside / Forsythoside F	CHEMBL506436 CHEMBL455827		1 / 0 / 3
C00034810	Calceolarioside C
C00034857	Hebeoside
C00034943	Newbouldioside A / (-)-Newbouldioside A
C00035177	Angoroside C		C413578
C00035379	Purpureaside B
C00035713	Osmanthuside I		C080858
C00035714	Osmanthuside J		C080859
C00036035	Alyssonoside		C077613
C00036040	Aragoside / (-)-Aragoside
C00036042	Ballotetroside
C00036138	Marruboside / (-)-Marruboside
C00036235	Velutinoside I	CHEMBL434389
C00036236	Velutinoside II
C00036501	O-Apiosylverbascoside / 2''-O-beta-Apiosylverbascoside
C00036800	beta-Hydroxyacteoside
C00036871	Campneoside I
C00036912	Cistanoside D	CHEMBL1714031		3 / 2 / 2
C00037437	Lugrandoside / (-)-Lugrandoside
C00037442	Luteoside A / (-)-Luteoside A	CHEMBL511027
C00037477	Markhamioside B / (-)-Markhamioside B
C00037478	Markhamioside C / (+)-Markhamioside C
C00037479	Markhamioside D / (-)-Markhamioside D
C00037480	Markhamioside E / (-)-Markhamioside E
C00037656	Plantalloside / (-)-Plantalloside
C00038592	Betonyoside F / (-)-Betonyoside F
C00038693	Campneoside II / (-)-Campneoside II
C00038792	Cistanoside C
C00039615	Leonoside B	CHEMBL428306
C00040370	Stachysoside B	CHEMBL436809 CHEMBL595544
C00043199	3''-O-Methylcrenatoside / (-)-3''-O-Methylcrenatoside	CHEMBL502701		1 / 4 / 2
C00044877	Ligupurpuroside A	CHEMBL442944
C00044878	Ligupurpuroside B	CHEMBL443461
C00044879	Ligupurpuroside C / (-)-Ligupurpuroside C
C00044881	Ligurobustoside N / (-)-Ligurobustoside N	CHEMBL502885
C00044985	Osmanthuside B / (-)-Osmanthuside B	CHEMBL448999
C00044986	Osmanthuside B6	CHEMBL449440
C00046045	Isocrenatoside	CHEMBL402471		1 / 4 / 2
C00046473	Trichosanthoside A / (-)-Trichosanthoside A	CHEMBL506843
C00046474	Trichosanthoside B / (-)-Trichosanthoside B	CHEMBL500194
C00047894	Fucatoside A / (-)-Fucatoside A	CHEMBL1077833		1 / 0 / 3
C00047895	Fucatoside B / (+)-Fucatoside B	CHEMBL1077834
C00047896	Fucatoside C / (+)-Fucatoside C	CHEMBL1077923
C00048045	Parvifloroside A / (-)-Parvifloroside A	CHEMBL1077924
C00048098	Samioside / (-)-Samioside	CHEMBL469152
C00049135	cis-Leucosceptoside A	CHEMBL450121		1 / 0 / 0
C00049136	cis-Martynoside / (-)-cis-Martynoside	CHEMBL234764 CHEMBL503531 CHEMBL2134071		1 / 7 / 3
C00049586	Angoroside A	CHEMBL506436 CHEMBL455827		1 / 0 / 3
C00049587	cis-Acteoside	CHEMBL231853 CHEMBL444478 CHEMBL1364101		12 / 1 / 1
C00049599	Scrophuloside B1 / (-)-Scrophuloside B1
C00049600	Scrophuloside B2 / (-)-Scrophuloside B2
C00049880	Luteoside C	CHEMBL502937

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P17252	Protein kinase C alpha type	Alpha	C00002744 C00002783 C00030657 C00031052 C00031070 C00049135 C00049587	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00030317 C00034798 C00047894 C00049586	0 / 3
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002783 C00036912 C00049587	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002783 C00049587	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002783 C00049587	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002783 C00049587	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002738 C00002769	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002783 C00049587	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002783 C00049587	0 / 0
O75496	Geminin	Unclassified protein	C00002783 C00049587	0 / 0
P10145	Interleukin-8	Secreted protein	C00002738 C00002769	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002783 C00049587	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00034597 C00049136	7 / 3
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002783 C00049587	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002783 C00049587	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002783 C00049587	0 / 0
P12821	Angiotensin-converting enzyme	M2	C00043199 C00046045	4 / 2
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002738 C00002769	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002738 C00002769	3 / 3
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002738 C00002769	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002738 C00002769	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00036912	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00030516	1 / 3
P45452	Collagenase 3	M10A	C00030516	1 / 1
P03956	Interstitial collagenase	M10A	C00030516	0 / 1
P08254	Stromelysin-1	M10A	C00030516	1 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00036912	2 / 2
P14780	Matrix metalloproteinase-9	M10A	C00030516	2 / 2
P39900	Macrophage metalloelastase	M10A	C00030516	0 / 0

37 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00002783
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00002783
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002783
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002783
894	CCND2, KIAK0002	cyclin D2	C00002783
896	CCND3	cyclin D3	C00002783
898	CCNE1, CCNE	cyclin E1	C00002783
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00002783
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00002783
1021	CDK6, PLSTIRE	cyclin-dependent kinase 6 (EC:2.7.11.22)	C00002783
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002783
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002783
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00002783
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002783
1869	E2F1, E2F-1, RBAP1, RBBP3, RBP3	E2F transcription factor 1	C00002783
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00002783
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002783
3458	IFNG, IFG, IFI	interferon, gamma	C00002783
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002783
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002783
3689	ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	C00002783
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002783
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002783
27035	NOX1, GP91-2, MOX1, NOH-1, NOH1	NADPH oxidase 1	C00002783
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002783
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002783
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002783
4087	SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2	SMAD family member 2	C00002783
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00002783
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00002783
7039	TGFA, TFGA	transforming growth factor, alpha	C00002783
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00002783
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002783
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002783
571	BACH1, BACH-1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	C00002738
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00002738
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00002738

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions