Species

KNApSAcK Entry

Organism name Sedum album
Genus Sedum
Family Crassulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Sedum album
Linked NCBI taxonomy ID 23029
Linked level species

Family

Family in NCBI taxonomy Crassulaceae
ID 3781

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005558 External link 512 Isorhamnetin 3-rhamnoside-7-glucoside
No. 1 No. 15
C00005563 External link 512 Isorhamnetin 7-sophoroside
No. 1 No. 15
C00005387 External link 512 Spiraeoside
CHEMBL402947
C080613
5 / 4 / 8 No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00005526 External link 512 Isorhamnetin 3-rhamnoside
/ 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL485261
No. 2 No. 15
C00005343 External link 512 Herbacetin 8-glucuronide
No. 2 No. 15
C00005691 External link 512 Gossypetin 8-glucuronide
CHEMBL1822703
C087346
0 / 1 No. 2 No. 15
C00005530 External link 512 Isorhamnetin 7-glucoside
/ Isorhamnetin 7-O-beta-D-glucopyranoside
No. 2 No. 15
C00001048 External link 512 Herbacetin
CHEMBL611029
No. 3 No. 15
C00005587 External link 512 Isorhamnetin 3-rhamnoside-7-sophoroside
No. 5 No. 15

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P15121 Aldose reductase Enzyme C00005374 C00005387 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005374 C00005387 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005374 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00005374 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005374 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005374 1 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005374 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00005374 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00005374 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005387 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00005374 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005374 0 / 0
O00255 Menin Unclassified protein C00005387 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00005387 1 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005374 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005374

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (10)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D010146 Pain C00005374
D004487 Edema C00005691