| Organism name | Apium graveolens |
|---|---|
| Genus | Apium |
| Family | Apiaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Apium graveolens |
|---|---|
| Linked NCBI taxonomy ID | 4045 |
| Linked level | species |
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001019
|
Apiin
|
CHEMBL1077561
CHEMBL1451695 CHEMBL1535342 |
C012186
|
7 / 4 / 7 | No. 1 | No. 15 |
|
|
|
C00004281
|
Luteolin 7-apiosyl-(1->2)-glucoside
/ Luteolin 7-O-[2-(beta-D-apiofuranosyl)-beta-D-glucopyranoside] |
No. 1 | No. 15 |
|
||||
|
C00004342
|
Graveobioside B
/ Luteolin 3'-methyl ether 7-apiosyl-(1->2)-glucoside |
CHEMBL2332117
|
No. 1 | No. 15 |
|
|||
|
C00005374
|
Quercetin
|
CHEMBL82242
CHEMBL479232 CHEMBL1437696 |
C012526
|
14 / 2 / 2 | 2 / 1 | No. 2 | No. 15 |
|
|
C00031677
|
Chrysoeriol 7-O-glucoside
/ Chrysoeriol 7-O-beta-D-glucopyranoside |
CHEMBL486391
|
No. 2 | No. 15 |
|
|||
|
C00001029
|
Chrysoeriol
/ Luteolin 3'-methyl ether |
CHEMBL214321
|
C007054
|
20 / 24 / 20 | 8 / 0 | No. 3 | No. 15 |
|
|
C00006834
|
Cyanidin 3-[6-(6-sinapylglucosyl)-2-xylosylgalactoside]
|
No. 7 | No. 15 |
|
||||
|
C00006832
|
Cyanidin 3-[6-(6-p-coumarylglucosyl)-2-xylosylgalactoside]
|
No. 7 | No. 15 |
|
||||
|
C00000674
|
Luteolin
|
CHEMBL151
|
D047311
|
99 / 91 / 95 | 76 / 6 | No. 71 | No. 15 |
|
|
C00003817
|
Apigenin
/ 5,7,4'-Trihydroxyflavone |
CHEMBL28
|
D047310
|
164 / 119 / 105 | 68 / 8 | No. 71 | No. 15 |
|
|
C00003186
|
beta-Selinene
|
C087920
|
No. 151 | No. 38 |
|
|||
|
C00019835
|
(-)-2,3-Dihydro-9-O-beta-glucosyloxy-2-isopropenyl-7H-furo[3,2-g][1]benzopyran-7-one
|
No. 491 | No. 25 |
|
||||
|
C00019957
|
5-Methoxy-8-O-beta-D-glucosyloxy-psoralen
|
No. 491 | No. 25 |
|
||||
|
C00000300
|
Seselin
/ Amyrolin / Seseline |
CHEMBL71358
|
2 / 0 / 0 | No. 750 | No. 25 |
|
||
|
C00002476
|
Herniarin
/ 7-Methoxycoumarin |
CHEMBL49732
|
C007929
|
23 / 10 / 12 | No. 864 | No. 25 |
|
|
|
C00000575
|
Bergaptan
|
CHEMBL24171
|
C022909
|
22 / 22 / 17 | 0 / 3 | No. 1282 | No. 25 |
|
|
C00000576
|
Xanthotoxin
|
CHEMBL416
|
D008730
|
104 / 55 / 45 | 22 / 18 | No. 1282 | No. 25 |
|
|
C00002762
|
Myristicin
|
CHEMBL481044
|
C005246
|
6 / 4 / 2 | 2 / 0 | No. 1917 | No. 6 |
|
|
C00002654
|
Guaiacol
/ o-Guaiacol |
CHEMBL13766
|
D006139
|
15 / 18 / 47 | 3 / 1 | No. 2352 |
|
|
|
C00019837
|
(+)-2,3-Dihydro-9-hydroxy-2[1-(6-sinapinoyl)beta-D-glucosyloxy-1-methylethyl]-7H-furo[3,2-g][1]benzopyran-7-one
|
No. 2585 |
|
|||||
|
C00002502
|
4,8,5'-Trimethylpsoralen
|
CHEMBL1475
|
D014307
|
95 / 36 / 34 | 0 / 5 | No. 3235 | No. 25 |
|
|
C00001193
|
Malonic acid
|
CHEMBL7942
|
C030290
|
6 / 1 / 5 | 1 / 2 | No. 5377 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000575 C00000674 C00001029 C00002476 C00002502 C00002762 C00003817 C00005374 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000575 C00000674 C00001019 C00002476 C00002502 C00003817 C00005374 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000575 C00000576 C00000674 C00002502 C00002762 C00003817 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000575 C00000576 C00000674 C00002502 C00003817 | 1 / 1 |
| P10275 | Androgen receptor | NR3C4 | C00000575 C00000576 C00000674 C00002654 C00003817 | 3 / 4 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000575 C00000576 C00000674 C00002502 C00003817 | 0 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000575 C00000576 C00000674 C00002654 C00003817 | 3 / 2 |
| P56817 | Beta-secretase 1 | A1A | C00000300 C00000575 C00000576 C00002476 C00003817 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000576 C00000674 C00001029 C00002502 C00003817 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000674 C00001019 C00001029 C00002762 C00003817 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000575 C00000576 C00000674 C00002502 C00003817 | 1 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000674 C00001029 C00002502 C00002654 C00003817 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000674 C00002762 C00003817 C00005374 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000576 C00000674 C00002502 C00002654 | 0 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000575 C00000674 C00002476 C00003817 | 3 / 3 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000576 C00002476 C00002502 C00002654 | 1 / 2 |
| O00255 | Menin | Unclassified protein | C00000674 C00001019 C00001029 C00003817 | 2 / 5 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000576 C00000674 C00002502 C00003817 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000674 C00002476 C00003817 C00005374 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000575 C00000674 C00002654 C00003817 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000576 C00000674 C00002502 C00002654 | 2 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000576 C00000674 C00002502 C00003817 | 0 / 1 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000576 C00000674 C00002502 C00003817 | 0 / 3 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000674 C00001019 C00001029 C00003817 | 1 / 2 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000576 C00000674 C00002502 C00003817 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000576 C00000674 C00002502 C00003817 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000674 C00002476 C00003817 C00005374 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000576 C00000674 C00002502 C00003817 | 0 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000674 C00001029 C00003817 C00005374 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000576 C00000674 C00002502 C00003817 | 1 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000575 C00000576 C00002502 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000576 C00002502 C00003817 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000575 C00000576 C00002502 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000576 C00002502 C00003817 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000674 C00002654 C00003817 | 7 / 37 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000576 C00002502 C00003817 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000576 C00002502 C00003817 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000576 C00002502 C00003817 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000674 C00001029 C00003817 | 2 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000576 C00002502 C00003817 | 1 / 8 |
| P17252 | Protein kinase C alpha type | Alpha | C00000576 C00002502 C00003817 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00000674 C00001019 C00001029 | 1 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000674 C00001019 C00003817 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00000674 C00001029 C00003817 | 4 / 2 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001029 C00002762 C00003817 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000576 C00002654 C00003817 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00000674 C00001029 C00003817 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000674 C00002762 C00003817 | 4 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000576 C00002502 C00003817 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000674 C00001029 C00003817 | 4 / 3 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000576 C00002502 C00003817 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000674 C00001029 C00003817 | 4 / 4 |
| P08183 | Multidrug resistance protein 1 | drug | C00000575 C00000674 C00003817 | 1 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000674 C00001029 C00003817 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000576 C00002502 C00003817 | 0 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000674 C00003817 C00005374 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000674 C00003817 C00005374 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000674 C00002476 C00003817 | 2 / 2 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000674 C00003817 C00005374 | 1 / 1 |
| P15121 | Aldose reductase | Enzyme | C00002476 C00005374 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000674 C00003817 | 3 / 1 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 0 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000674 C00003817 | 11 / 10 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000576 C00002502 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000576 C00002502 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000576 C00002502 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000576 C00002502 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 0 / 0 |
| Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00000674 C00003817 | 1 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00000674 C00003817 | 0 / 0 |
| Q15046 | Lysine--tRNA ligase | Enzyme | C00000674 C00003817 | 2 / 1 |
| O95271 | Tankyrase-1 | Enzyme | C00000674 C00003817 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000674 C00005374 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000576 C00002502 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000674 C00003817 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000576 C00002502 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000576 C00002502 | 0 / 0 |
| P20813 | Cytochrome P450 2B6 | Cytochrome P450 2B6 | C00000575 C00000576 | 1 / 0 |
| P23443 | Ribosomal protein S6 kinase beta-1 | p70 | C00000576 C00003817 | 0 / 0 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00000674 C00003817 | 0 / 0 |
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00000674 C00003817 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000576 C00002502 | 1 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000674 C00003817 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000576 C00002502 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000576 C00002502 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000576 C00002502 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000576 C00002502 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000576 C00002502 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000576 C00002502 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00000674 C00003817 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000576 C00003817 | 2 / 3 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000576 C00002502 | 2 / 0 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000576 C00002502 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000576 C00002502 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000576 C00002502 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000576 C00002502 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001029 C00003817 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000576 C00002502 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000576 C00002502 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000576 C00002502 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00000674 C00003817 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000576 C00002502 | 1 / 1 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000576 C00002502 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000576 C00002502 | 1 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 1 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000576 C00002502 | 1 / 1 |
| P04062 | Glucosylceramidase | Enzyme | C00000674 C00003817 | 6 / 4 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000576 C00002502 | 0 / 0 |
| Q9H2K2 | Tankyrase-2 | Enzyme | C00000674 C00003817 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000674 C00003817 | 1 / 1 |
| P08254 | Stromelysin-1 | M10A | C00000674 C00002654 | 1 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000674 C00003817 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000576 C00002502 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00000674 C00001029 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00000576 C00002502 | 2 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000576 C00002502 | 2 / 2 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00000674 C00003817 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000576 C00002502 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000576 C00002502 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000576 C00002502 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000576 C00002502 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000576 C00002502 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000576 C00002502 | 1 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000674 C00002654 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000674 C00003817 | 1 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000576 C00002502 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000576 C00002502 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000576 C00002502 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000576 C00002502 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000674 C00003817 | 1 / 1 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000576 C00002502 | 1 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002476 C00002654 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00000674 C00003817 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000576 C00002502 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000576 C00002502 | 0 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001029 C00003817 | 1 / 1 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000674 C00003817 | 2 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000576 C00002502 | 1 / 0 |
| P09874 | Poly [ADP-ribose] polymerase 1 | Enzyme | C00000674 C00003817 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000576 C00002502 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000674 C00003817 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000674 C00003817 | 1 / 4 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000576 C00002502 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000674 C00002654 | 1 / 3 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000575 C00000576 | 7 / 3 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000674 C00001019 | 0 / 0 |
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00000674 C00003817 | 0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00000674 C00003817 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00000674 C00003817 | 0 / 0 |
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 |
| Q09470 | Potassium voltage-gated channel subfamily A member 1 | KCNA, Kv1.x (Shaker) | C00000575 C00000576 | 1 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000576 C00002502 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000576 C00002502 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000576 C00002502 | 2 / 1 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00001029 C00003817 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000576 C00002502 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000576 C00002502 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001029 C00003817 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000576 C00002502 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000576 C00002502 | 1 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000576 C00002502 | 1 / 0 |
| P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00000674 C00003817 | 0 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000576 C00002502 | 0 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000576 C00002502 | 0 / 0 |
| P06276 | Cholinesterase | Hydrolase | C00000674 C00003817 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000576 C00002502 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000576 C00002502 | 3 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005374 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000674 | 1 / 1 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000674 | 0 / 0 |
| P45452 | Collagenase 3 | M10A | C00000674 | 1 / 1 |
| P49137 | MAP kinase-activated protein kinase 2 | CAMK serine/threonine protein kinase MAPKAPK | C00003817 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000674 | 2 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00003817 | 0 / 0 |
| P00338 | L-lactate dehydrogenase A chain | Enzyme | C00001193 | 1 / 5 |
| P14679 | Tyrosinase | Oxidoreductase | C00000674 | 4 / 2 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003817 | 2 / 2 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000576 | 1 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00001193 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002476 | 0 / 1 |
| Q9GZT4 | Serine racemase | Enzyme | C00001193 | 0 / 0 |
| Q9Y4K4 | Mitogen-activated protein kinase kinase kinase kinase 5 | STE serine/threonine protein kinase KHS subfamily | C00003817 | 0 / 0 |
| Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | C00003817 | 1 / 1 |
| O15264 | Mitogen-activated protein kinase 13 | p38 | C00003817 | 0 / 0 |
| Q15418 | Ribosomal protein S6 kinase alpha-1 | Rskb | C00003817 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00003817 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003817 | 1 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00003817 | 5 / 2 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00003817 | 0 / 0 |
| P09769 | Tyrosine-protein kinase Fgr | Src | C00003817 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00003817 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002476 | 1 / 2 |
| O14763 | Tumor necrosis factor receptor superfamily member 10B | Unclassified protein | C00000674 | 1 / 0 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00003817 | 4 / 4 |
| P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Enzyme | C00002476 | 1 / 1 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002476 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000674 | 0 / 0 |
| P16389 | Potassium voltage-gated channel subfamily A member 2 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
| O75582 | Ribosomal protein S6 kinase alpha-5 | CAMK serine/threonine protein kinase MSKB subfamily | C00003817 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00002476 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00000674 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00000674 | 0 / 0 |
| P51570 | Galactokinase | Enzyme | C00000674 | 1 / 1 |
| P54132 | Bloom syndrome protein | Enzyme | C00000674 | 1 / 2 |
| Q8IW41 | MAP kinase-activated protein kinase 5 | CAMK serine/threonine protein kinase MAPKAPK | C00003817 | 0 / 0 |
| O75116 | Rho-associated protein kinase 2 | Rock | C00003817 | 0 / 0 |
| Q00796 | Sorbitol dehydrogenase | Enzyme | C00002476 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003817 | 0 / 0 |
| P07948 | Tyrosine-protein kinase Lyn | Src | C00003817 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00003817 | 0 / 0 |
| P14920 | D-amino-acid oxidase | Enzyme | C00001193 | 0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00003817 | 4 / 1 |
| O00141 | Serine/threonine-protein kinase Sgk1 | AGC serine/threonine protein kinase SGK subfamily | C00003817 | 0 / 0 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005374 | 0 / 0 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00003817 | 0 / 0 |
| P49327 | Fatty acid synthase | Transferase | C00000674 | 0 / 0 |
| P68400 | Casein kinase II subunit alpha | Ck2 | C00003817 | 0 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00003817 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003817 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00003817 | 1 / 0 |
| Q99489 | D-aspartate oxidase | Enzyme | C00001193 | 0 / 0 |
| P17658 | Potassium voltage-gated channel subfamily A member 6 | K | C00000575 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003817 | 5 / 1 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000674 | 0 / 1 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00003817 | 0 / 0 |
| O14757 | Serine/threonine-protein kinase Chk1 | Chk1 | C00003817 | 0 / 0 |
| P39900 | Macrophage metalloelastase | M10A | C00000674 | 0 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00000300 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00002654 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002476 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00002476 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00002476 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000674 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00002476 | 0 / 0 |
| P41240 | Tyrosine-protein kinase CSK | Csk | C00003817 | 0 / 0 |
| P22460 | Potassium voltage-gated channel subfamily A member 5 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000674 | 0 / 0 |
| P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Ampk | C00003817 | 0 / 0 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00003817 | 0 / 0 |
| O15530 | 3-phosphoinositide-dependent protein kinase 1 | Pdk1 | C00003817 | 0 / 0 |
| P43405 | Tyrosine-protein kinase SYK | Syk | C00003817 | 0 / 0 |
| P22001 | Potassium voltage-gated channel subfamily A member 3 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00003817 | 1 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00002476 | 1 / 1 |
| P53778 | Mitogen-activated protein kinase 12 | p38 | C00003817 | 0 / 0 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00002476 | 1 / 1 |
| Q15759 | Mitogen-activated protein kinase 11 | p38 | C00003817 | 0 / 0 |
| O14980 | Exportin-1 | Unclassified protein | C00002476 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002654 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000674 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00003817 | 1 / 1 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00003817 | 0 / 0 |
| Q16798 | NADP-dependent malic enzyme, mitochondrial | Enzyme | C00001193 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003817 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003817 | 2 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00003817 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000576 | 0 / 0 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00003817 | 0 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00003817 | 1 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00003817 | 1 / 1 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00003817 | 0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00003817 | 1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00003817 | 0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00003817 | 0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00003817 | 0 / 0 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00003817 | 0 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00003817 | 0 / 0 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00003817 | 0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00003817 | 0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00003817 | 4 / 2 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00003817 | 0 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00003817 | 0 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00003817 | 1 / 0 |
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00003817 | 0 / 0 |
| P53779 | Mitogen-activated protein kinase 10 | Jnk | C00003817 | 0 / 1 |
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00003817 | 0 / 0 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000576 | 1 / 0 |
| P48547 | Potassium voltage-gated channel subfamily C member 1 | K | C00000575 | 0 / 0 |
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00005374 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00003817 | 3 / 0 |
| P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00003817 | 0 / 0 |
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00003817 | 0 / 0 |
| P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00003817 | 0 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00003817 | 0 / 0 |
| Q9HCP0 | Casein kinase I isoform gamma-1 | Ck1 | C00003817 | 0 / 0 |
| P48730 | Casein kinase I isoform delta | Ck1 | C00003817 | 1 / 0 |
| P49674 | Casein kinase I isoform epsilon | Ck1 | C00003817 | 0 / 0 |
| P78368 | Casein kinase I isoform gamma-2 | Ck1 | C00003817 | 0 / 0 |
| P48729 | Casein kinase I isoform alpha | Ck1 | C00003817 | 0 / 0 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00003817 | 1 / 1 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00002502 | 0 / 3 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00000674 | 2 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000576 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000576
C00000674
C00001029
C00003817
C00005374 |
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000576
C00000674
C00002762
C00003817
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000576
C00001029
C00002762
C00003817
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000674
C00001029
C00003817
C00005374
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000674
C00001029
C00003817
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000674
C00001029
C00003817
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000576
C00000674
C00003817
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000576
C00000674
C00003817
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00000576
C00000674
C00003817
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000576
C00000674
C00003817
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000576
C00000674
C00003817
|
| 4793 | NFKBIB, IKBB, TRIP9 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
C00000674
C00003817
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00000674
C00003817
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000576
C00000674
|
| 7161 | TP73, P73 | tumor protein p73 |
C00000674
C00003817
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00000674
C00003817
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00000674
C00003817
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000674
C00003817
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00000674
C00003817
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00000674
C00003817
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00000576
C00000674
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00000674
C00003817
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00000674
C00003817
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00000674
C00003817
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000576
C00003817
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00000674
C00003817
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00000674
C00003817
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00000674
C00003817
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000674
C00003817
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00000674
C00003817
|
| 8839 | WISP2, CCN5, CT58, CTGF-L | WNT1 inducible signaling pathway protein 2 |
C00000674
C00003817
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000576
C00003817
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000674
C00003817
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00000674
C00003817
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000674
C00003817
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00000674
C00003817
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00000674
C00003817
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00000674
C00003817
|
| 958 | CD40, Bp50, CDW40, TNFRSF5, p50 | CD40 molecule, TNF receptor superfamily member 5 |
C00000674
C00003817
|
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00000674
C00003817
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00000674
C00003817
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00000674
C00003817
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00000674
C00003817
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00000674
C00003817
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000674
C00003817
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00000674
C00003817
|
| 1586 | CYP17A1, CPT7, CYP17, P450C17, S17AH | cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) |
C00003817
|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003817
|
| 1589 | CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B | cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10) |
C00003817
|
| 2064 | ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) |
C00003817
|
| 1584 | CYP11B1, CPN1, CYP11B, FHI, P450C11 | cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4) |
C00003817
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00003817
|
| 6387 | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B | chemokine (C-X-C motif) ligand 12 |
C00003817
|
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00003817
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00003817
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00003817
|
| 3284 | HSD3B2, HSD3B, HSDB, SDR11E2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) |
C00003817
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00003817
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00003817
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00000576
|
| 3355109 |
C00000576
|
||
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00000576
|
| 3034 | HAL, HIS, HSTD | histidine ammonia-lyase (EC:4.3.1.3) |
C00000576
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00000576
|
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00000576
|
| 1553 | CYP2A13, CPAD, CYP2A, CYPIIA13 | cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1) |
C00000576
|
| 5241 | PGR, NR3C3, PR | progesterone receptor |
C00003817
|
| 5562 | PRKAA1, AMPK, AMPKa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) |
C00003817
|
| 8824 | CES2, CE-2, CES2A1, PCE-2, iCE | carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56) |
C00000576
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00000576
|
| 6198 | RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha | ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) |
C00003817
|
| 8553 | BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14 | basic helix-loop-helix family, member e40 |
C00000576
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00003817
|
| 6783 | SULT1E1, EST, EST-1, ST1E1, STE | sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) |
C00003817
|
| 760 | CA2, CA-II, CAC, CAII, Car2 | carbonic anhydrase II (EC:4.2.1.1) |
C00002654
|
| 759 | CA1, CA-I, CAB, Car1 | carbonic anhydrase I (EC:4.2.1.1) |
C00002654
|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00002654
|
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00001193
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00003817
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00003817
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00003817
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00003817
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00003817
|
| 7402 | UTRN, DMDL, DRP, DRP1 | utrophin |
C00003817
|
| 4835 | NQO2, DHQV, DIA6, NMOR2, QR2 | NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2) |
C00001029
|
| 4544 | MTNR1B, FGQTL2, MEL-1B-R, MT2 | melatonin receptor 1B |
C00001029
|
| 4543 | MTNR1A, MEL-1A-R, MT1 | melatonin receptor 1A |
C00001029
|
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00000674
|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00000674
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00000674
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00000674
|
| 890 | CCNA2, CCN1, CCNA | cyclin A2 |
C00000674
|
| 972 | CD74, DHLAG, HLADG, II, Ia-GAMMA | CD74 molecule, major histocompatibility complex, class II invariant chain |
C00000674
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00000674
|
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00000674
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00000674
|
| 1950 | EGF, HOMG4, URG | epidermal growth factor |
C00000674
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00000674
|
| 1958 | EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 | early growth response 1 |
C00000674
|
| 2354 | FOSB, AP-1, G0S3, GOS3, GOSB | FBJ murine osteosarcoma viral oncogene homolog B |
C00000674
|
| 4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta |
C00000674
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000674
|
| 3726 | JUNB, AP-1 | jun B proto-oncogene |
C00000674
|
| 3727 | JUND, AP-1 | jun D proto-oncogene |
C00000674
|
| 5602 | MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK | mitogen-activated protein kinase 10 (EC:2.7.11.24) |
C00000674
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00000674
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00000674
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00000674
|
| 9572 | NR1D1, EAR1, THRA1, THRAL, ear-1, hRev | nuclear receptor subfamily 1, group D, member 1 |
C00000674
|
| 5347 | PLK1, PLK, STPK13 | polo-like kinase 1 (EC:2.7.11.21) |
C00000674
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000674
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00000674
|
| 2810 | SFN, YWHAS | stratifin |
C00000674
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00000674
|
| 29110 | TBK1, NAK, T2K | TANK-binding kinase 1 (EC:2.7.11.1) |
C00000674
|
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) |
C00000674
|
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
C00000674
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00000674
|
| 10451 | VAV3 | vav 3 guanine nucleotide exchange factor |
C00000674
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00000674
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #615224 | Advanced sleep phase syndrome, familial, 2; fasps2 |
P48730
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 P47869 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #612240 | Atrial fibrillation, familial, 7; atfb7 |
P22460
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P31749
P38398 |
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib |
Q15046
|
| #114500 | Colorectal cancer; crc |
P18054
P31749 P84022 Q14191 |
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #604931 | Cortisone reductase deficiency 1; cortrd1 |
P28845
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #613916 | Deafness, autosomal recessive 89; dfnb89 |
Q15046
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #614546 | Efavirenz, poor metabolism of |
P20813
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #160120 | Episodic ataxia, type 1; ea1 |
Q09470
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #230200 | Galactokinase deficiency |
P51570
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd |
Q12791
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #612933 | Glycogen storage disease xi; gsd11 |
P00338
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #176920 | Proteus syndrome |
P31749
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #603903 | Sickle cell anemia |
P68871
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
O14763
P04637 |
| %612223 | Stature quantitative trait locus 11; stqtl11 |
Q00534
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00069 | Glycogen storage diseases (GSD) |
P00338
(related)
P10253 (related) |
| H00010 | Multiple myeloma |
P00338
(marker)
P04637 (related) |
| H00023 | Testicular cancer |
P00338
(marker)
|
| H00035 | Ewing's sarcoma |
P00338
(marker)
|
| H00043 | Neuroblastoma |
P00338
(marker)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) P68871 (marker) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
P16473 (related) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) Q15046 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P28907 (marker) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H00731 | Atrial fibrillation |
P22460
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01111 | Cortisone reductase deficiency (CRD) |
P28845
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00070 | Galactosemia |
P51570
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
P53779
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00749 | Episodic ataxias |
Q09470
(related)
|
| H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) |
Q12791
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D011565 | Psoriasis |
C00000575
C00000576 C00002502 |
| D010146 | Pain |
C00005374
C00002654 |
| D009182 | Mycosis Fungoides |
C00000576
C00002502 |
| D014820 | Vitiligo |
C00000576
C00002502 |
| D004485 | Eczema |
C00000576
C00002502 |
| D056486 | Drug-Induced Liver Injury |
C00000576
C00003817 |
| D011693 | Purpura |
C00000576
|
| D020258 | Neurotoxicity Syndromes |
C00001193
|
| D001930 | Brain Injuries |
C00001193
|
| D006261 | Headache |
C00000576
|
| D007674 | Kidney Diseases |
C00000576
|
| D017114 | Liver Failure, Acute |
C00000576
|
| D008175 | Lung Neoplasms |
C00000576
|
| D016410 | Lymphoma, T-Cell, Cutaneous |
C00000576
|
| D008881 | Migraine Disorders |
C00000576
|
| D010787 | Photosensitivity Disorders |
C00000575
|
| D009325 | Nausea |
C00000576
|
| D000857 | Olfaction Disorders |
C00000576
|
| D015746 | Abdominal Pain |
C00000576
|
| D007319 | Sleep Initiation and Maintenance Disorders |
C00000576
|
| D014006 | Tinea Capitis |
C00000576
|
| D015837 | Vestibular Diseases |
C00000576
|
| D006505 | Hepatitis |
C00000575
|
| D011605 | Psychoses, Substance-Induced |
C00002502
|
| D000257 | Adenoviridae Infections |
C00003817
|
| D001943 | Breast Neoplasms |
C00003817
|
| D003110 | Colonic Neoplasms |
C00003817
|
| D009361 | Neoplasm Invasiveness |
C00003817
|
| D009362 | Neoplasm Metastasis |
C00003817
|
| D011041 | Poisoning |
C00003817
|
| D011471 | Prostatic Neoplasms |
C00003817
|
| D009202 | Cardiomyopathies |
C00000674
|
| D002386 | Cataract |
C00000674
|
| D005483 | Flushing |
C00000674
|
| D006529 | Hepatomegaly |
C00000674
|
| D008103 | Liver Cirrhosis |
C00000674
|
| D010051 | Ovarian Neoplasms |
C00000674
|