PCIDB

KNApSAcK Metabolite C00002476

Metabolite

KNApSAcK Entry

id C00002476
Name Herniarin / 7-Methoxycoumarin
CAS RN 531-59-9
Standard InChI InChI=1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3
Standard InChI (Main Layer) InChI=1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3

Cluster

Phytochemical cluster No. 25
KCF-S cluster No. 864

Link

ChEMBL

By standard InChI CHEMBL49732
By standard InChI Main Layer CHEMBL49732

KEGG

By LinkDB C09268

CTD

By CAS RN C007929

Human Protein / Gene in interaction

23 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL49732 CHEMBL1044456 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL49732 CHEMBL1044455 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL49732 CHEMBL1044458 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL49732 CHEMBL1041799 (1)
1 / 2
P23280 Carbonic anhydrase 6 Lyase CHEMBL49732 CHEMBL1044457 (1)
0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL49732 CHEMBL1044462 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL49732 CHEMBL1614458 (2)
0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme CHEMBL49732 CHEMBL1656573 (1) CHEMBL1656574 (1)
1 / 1
O43570 Carbonic anhydrase 12 Lyase CHEMBL49732 CHEMBL1044460 (1)
1 / 2
P15121 Aldose reductase Enzyme CHEMBL49732 CHEMBL1260797 (1) CHEMBL1942674 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL49732 CHEMBL1041798 (1)
0 / 0
P56817 Beta-secretase 1 A1A CHEMBL49732 CHEMBL1936881 (1) CHEMBL1936882 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL49732 CHEMBL1044459 (1)
0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL49732 CHEMBL1613910 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL49732 CHEMBL1614038 (2)
2 / 2
Q00796 Sorbitol dehydrogenase Enzyme CHEMBL49732 CHEMBL1260799 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL49732 CHEMBL1614211 (1)
0 / 0
P07451 Carbonic anhydrase 3 Lyase CHEMBL49732 CHEMBL1044453 (1)
0 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL49732 CHEMBL1044454 (1)
1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme CHEMBL49732 CHEMBL1656575 (1) CHEMBL1656576 (1)
1 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL49732 CHEMBL1794536 (1)
0 / 0
O14980 Exportin-1 Unclassified protein CHEMBL49732 CHEMBL1120677 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL49732 CHEMBL1613914 (2)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#218030 Apparent mineralocorticoid excess; ame P80365
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#119900 Digital clubbing, isolated congenital P15428
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (12)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)