PCIDB

Eupatorium triplinerve

Species

KNApSAcK Entry

Organism name Eupatorium triplinerve
Genus Eupatorium
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ayapana triplinervis
Linked NCBI taxonomy ID 1090619
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00004647 External link 512 Ayanin
/ 3,7,4'-Tri-O-methylquercetin
/ 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone
/ 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL74898
18 / 10 / 2 No. 3 No. 15
C00002476 External link 512 Herniarin
/ 7-Methoxycoumarin
CHEMBL49732
C007929
23 / 10 / 12 No. 864 No. 25

Human Protein / Gene in interactions

41 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs C00004647 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002476 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002476 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002476 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00002476 1 / 2
P08183 Multidrug resistance protein 1 drug C00004647 1 / 0
P23280 Carbonic anhydrase 6 Lyase C00002476 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002476 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002476 0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme C00002476 1 / 1
O43570 Carbonic anhydrase 12 Lyase C00002476 1 / 2
P15121 Aldose reductase Enzyme C00002476 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002476 0 / 0
P56817 Beta-secretase 1 A1A C00002476 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002476 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002476 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00004647 2 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002476 2 / 2
Q00796 Sorbitol dehydrogenase Enzyme C00002476 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002476 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002476 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00002476 1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00002476 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00002476 0 / 0
O14980 Exportin-1 Unclassified protein C00002476 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002476 0 / 0
Q13748 Tubulin alpha-3C/D chain Structural C00004647 0 / 0
P68366 Tubulin alpha-4A chain Structural C00004647 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00004647 1 / 0
P04350 Tubulin beta-4A chain Structural C00004647 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00004647 0 / 0
P07437 Tubulin beta chain Structural C00004647 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00004647 1 / 1
P68371 Tubulin beta-4B chain Structural C00004647 0 / 0
Q13509 Tubulin beta-3 chain Structural C00004647 2 / 1
P68363 Tubulin alpha-1B chain Unclassified protein C00004647 0 / 0
Q13885 Tubulin beta-2A chain Structural C00004647 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00004647 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00004647 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00004647 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00004647 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#218030 Apparent mineralocorticoid excess; ame P80365
#614490 Blood group, junior system; jr Q9UNQ0
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#119900 Digital clubbing, isolated congenital P15428
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#612244 Inflammatory bowel disease 13; ibd13 P08183
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#600852 Retinitis pigmentosa 17; rp17 P22748
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (14)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)