Species

KNApSAcK Entry

Organism name Trichogonia grazielae
Genus Trichogonia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Asteraceae
Linked NCBI taxonomy ID 4210
Linked level family

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003110 External link 512 Caryophyllene
/ (E)-Caryophyllene
/ beta-Caryophyllene
/ (-)-(E)-Caryophyllene
/ (E)-beta-Caryophyllene
CHEMBL445740
CHEMBL448700
2 / 3 / 7 No. 478 No. 38
C00021230 External link 512 Aromadendrene
/ (+)-Aromadendrene
/ (+)-Aromadendr-7(15)-ene
CHEMBL509805
CHEMBL596664
No. 640
C00002476 External link 512 Herniarin
/ 7-Methoxycoumarin
CHEMBL49732
C007929
23 / 10 / 12 No. 864 No. 25
C00003147 External link 512 Humulene
/ alpha-Caryophyllene
/ (+/-)-alpha-Humulene
CHEMBL251280
C042686
No. 1421 No. 38
C00020134 External link 512 gamma-Muurolen-15-oic acid
No. 2025
C00023266 External link 512 2,2-Dimethyl-6-vinylchroman-4-one
No. 2514
C00023271 External link 512 2,2-Dimethyl-6-(1-hydroxyethyl)chroman-4-one
No. 2514
C00011720 External link 512 Germacrene D
/ (-)-Germacrene D
CHEMBL105432
CHEMBL1836650
No. 2639 No. 38
C00023264 External link 512 4-Methoxy-3-(isopenten-2-yl)acetophenone
No. 2709
C00023270 External link 512 1-[2-Hydroxy-5-(1-hydroxyethyl)phenyl]-3-methyl-2-buten-1-one
No. 2709
C00023268 External link 512 2-Senecioyl-4-[1-angeloyloxyethyl]-phenol
No. 4315
C00023265 External link 512 2-(3',3'-Dimethylallyl)-4-(1-angeloyloxyethyl)-anisole
No. 4315

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002476 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002476 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002476 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00002476 1 / 2
P23280 Carbonic anhydrase 6 Lyase C00002476 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002476 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002476 0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme C00002476 1 / 1
O43570 Carbonic anhydrase 12 Lyase C00002476 1 / 2
P15121 Aldose reductase Enzyme C00002476 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002476 0 / 0
P56817 Beta-secretase 1 A1A C00002476 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002476 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002476 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002476 2 / 2
Q00796 Sorbitol dehydrogenase Enzyme C00002476 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002476 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002476 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00002476 1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00002476 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00002476 0 / 0
O14980 Exportin-1 Unclassified protein C00002476 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002476 0 / 0
O00255 Menin Unclassified protein C00003110 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003110 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#218030 Apparent mineralocorticoid excess; ame P80365
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#119900 Digital clubbing, isolated congenital P15428
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (19)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)