PCIDB

KNApSAcK Metabolite C00002762

Metabolite

KNApSAcK Entry

id C00002762
Name Myristicin
CAS RN 607-91-0
Standard InChI InChI=1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3
Standard InChI (Main Layer) InChI=1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3

Cluster

Phytochemical cluster No. 6
KCF-S cluster No. 1917

Link

ChEMBL

By standard InChI CHEMBL481044
By standard InChI Main Layer CHEMBL481044

KEGG

By LinkDB C10480

CTD

By CAS RN C005246

Human Protein / Gene in interaction

6 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL481044 CHEMBL1613842 (1)
4 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL481044 CHEMBL1794524 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL481044 CHEMBL1614458 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL481044 CHEMBL2114843 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL481044 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL481044 CHEMBL1794483 (1)
0 / 0

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C005246 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein affects the oxidation of myristicin affects oxidation
protein 12523956
C005246 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) CYP3A4 protein affects the oxidation of myristicin affects oxidation
protein 12523956

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (2)

KEGG disease name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)