Daucus carota

• Index
• Plant Species
• Natural Activity
• Metabolite list (34)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Daucus carota
Genus	Daucus
Family	Apiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Daucus carota
Linked NCBI taxonomy ID	4039
Linked level	species

Family

Family in NCBI taxonomy	Apiaceae
ID	4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (12)

Species	Activity
Daucus carota L. subsp. Carota	Antilithic
Daucus carota L. subsp. Carota	Aphrodisiac
Daucus carota L. subsp. Carota	Cardioactive
Daucus carota L. subsp. Carota	Carminative
Daucus carota L. subsp. Carota	Chemopreventive
Daucus carota L. subsp. Carota	Contraceptive
Daucus carota L. subsp. Carota	Diuretic
Daucus carota L. subsp. Carota	Emmenagogue
Daucus carota L. subsp. Carota	Hepatoprotective
Daucus carota L. subsp. Carota	Hypotensive
Daucus carota L. subsp. Carota	Myorelaxant
Daucus carota L. subsp. Carota	Vasdodilator

Metabolite list (34)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006655	Cyanidin 3-lathyroside					No. 1	No. 15
C00001067	Luteolin 7-O-(6''-malonylglucoside)					No. 2	No. 15
C00002374	Chrysanthemin / Cyanidin 3-O-glucoside	CHEMBL257839 CHEMBL1197952	C114438	1 / 0 / 1		No. 2	No. 15
C00006670	Cyanidin 3-glucosyl-(1->6)-[xylosyl-(1->2)-galactoside]					No. 5	No. 15
C00006832	Cyanidin 3-[6-(6-p-coumarylglucosyl)-2-xylosylgalactoside]					No. 7	No. 15
C00006833	Cyanidin 3-[6-(6-ferulylglucosyl)-2-xylosylgalactoside]					No. 7	No. 15
C00006834	Cyanidin 3-[6-(6-sinapylglucosyl)-2-xylosylgalactoside]					No. 7	No. 15
C00006831	Cyanidin 3-[6-(6-p-hydroxybenzoylglucosyl)-2-xylosylgalactoside]					No. 7	No. 15
C00000919	beta-Carotene	CHEMBL1293 CHEMBL1966639	D019207	7 / 12 / 11	104 / 19	No. 26	No. 59
C00003765	alpha-Carotene					No. 26	No. 59
C00000007	GA7 / Gibberellin A7					No. 40	No. 41
C00000004	GA4 / Gibberellin A4					No. 40	No. 41
C00000001	GA1 / Gibberellin A1		C422660			No. 40	No. 41
C00004330	Luteolin 4'-sulfate					No. 51	No. 15
C00000911	Lycopene / all-trans-Lycopene	CHEMBL501174 CHEMBL1984187	C015329	6 / 13 / 13	84 / 13	No. 97	No. 59
C00000934	zeta-Carotene					No. 97	No. 59
C00003766	delta-Carotene					No. 131	No. 59
C00000926	gamma-Carotene					No. 131	No. 59
C00002760	Methylisoeugenol	CHEMBL465829 CHEMBL1164609				No. 310	No. 6
C00021417	Carota-1,4-beta-oxide					No. 392	No. 38
C00003124	Daucol					No. 392	No. 38
C00007242	beta-Bisabolene / l-beta-Bisabolene / (-)-beta-Bisabolene	CHEMBL444389 CHEMBL1077088 CHEMBL2001434				No. 701	No. 38
C00002739	Elemicin	CHEMBL458690	C002135			No. 723	No. 6
C00001283	Falcarindiol	CHEMBL69018 CHEMBL1094112	C034379	3 / 0 / 0		No. 940	No. 69
C00000096	9-Ribosyl-trans-zeatin / Zeatin-9-beta-D-ribofuranoside					No. 989
C00003109	Carotol					No. 1187	No. 38
C00001497	3' 5'-cyclic AMP	CHEMBL9871 CHEMBL316966 CHEMBL1365681 CHEMBL1416083 CHEMBL1741513 CHEMBL2359042	D000242	29 / 24 / 19	80 / 7	No. 1201
C00003004	6-Methoxymellein	CHEMBL449604				No. 1274
C00000554	6HM / 6-Hydroxymellein	CHEMBL446047	C070622			No. 1274
C00002762	Myristicin	CHEMBL481044	C005246	6 / 4 / 2	2 / 0	No. 1917	No. 6
C00000094	2iP / N6-(delta2-Isopentenyl)adenine	CHEMBL476189	C001478	5 / 2 / 3	18 / 0	No. 2879
C00021380	Daucene					No. 4056	No. 38
C00002491	Peucedanin	CHEMBL1410943		10 / 8 / 6		No. 4483	No. 25
C00001533	Cucumopine		C082688			No. 6474

Human Protein / Gene in interactions

49 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00000911 C00000919 C00001497 C00002762	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000919 C00002491 C00002762	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000094 C00001497 C00002762	0 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000911 C00001497 C00002491	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000911 C00000919 C00001497	11 / 10
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000911 C00001497 C00002491	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000094 C00001497	1 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000919 C00001497	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000094 C00001497	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000094 C00001497	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000094 C00001497	0 / 1
O15439	Multidrug resistance-associated protein 4	Unclassified protein	C00001497	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00001497	3 / 1
P54132	Bloom syndrome protein	Enzyme	C00001497	1 / 2
P11473	Vitamin D3 receptor	NR1I1	C00000911	2 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001283	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00001283	0 / 0
Q9Y694	Solute carrier family 22 member 7	Unclassified protein	C00001497	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002491	2 / 2
P28907	ADP-ribosyl cyclase 1	Enzyme	C00002374	0 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002491	2 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001497	0 / 0
Q16280	Cyclic nucleotide-gated olfactory channel	Unclassified protein	C00001497	0 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00001497	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00001283	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001497	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001497	1 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00002762	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001497	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002491	3 / 3
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002491	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002491	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001497	2 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002491	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002762	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00001497	1 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000911	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002491	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002762	4 / 1
Q8WZA2	Rap guanine nucleotide exchange factor 4	Unclassified protein	C00001497	0 / 0
O15440	Multidrug resistance-associated protein 5	Unclassified protein	C00001497	0 / 0
Q08493	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	PDE_4C	C00001497	0 / 0
Q07343	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	PDE_4B	C00001497	0 / 0
P27815	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	PDE_4A	C00001497	0 / 0
Q08499	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	PDE_4D	C00001497	1 / 0
Q96J66	ATP-binding cassette sub-family C member 11	Unclassified protein	C00001497	1 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000919	0 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000919	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000919	0 / 0

269 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000911 C00000919 C00002762
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000911 C00000919 C00001497
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000911 C00000919 C00001497
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000911 C00000919 C00001497
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000911 C00001497
4842	NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS	nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)	C00000911 C00000919
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000911 C00000919
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00000911 C00001497
3713	IVL	involucrin	C00000911 C00000919
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00000911 C00001497
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000919 C00001497
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000919 C00001497
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000911 C00001497
673	BRAF, B-RAF1, BRAF1, NS7, RAFB1	v-raf murine sarcoma viral oncogene homolog B (EC:2.7.11.1)	C00000911 C00001497
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00000094 C00001497
3855	KRT7, CK7, K2C7, K7, SCL	keratin 7	C00000919
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000094
7431	VIM, CTRCT30	vimentin	C00000094
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002762
7029	TFDP2, DP2	transcription factor Dp-2 (E2F dimerization partner 2)	C00000094
118	ADD1, ADDA	adducin 1 (alpha)	C00000911
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00000911
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000911
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000911
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00000911
571	BACH1, BACH-1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	C00000911
8314	BAP1, HUCEP-13, UCHL2	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (EC:3.4.19.12)	C00000911
6286	S100P, MIG9	S100 calcium binding protein P	C00000094
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000911
847	CAT	catalase (EC:1.11.1.6)	C00000911
6016	RIT1, NS8, RIBB, RIT, ROC1	Ras-like without CAAX 1	C00000094
898	CCNE1, CCNE	cyclin E1	C00000911
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00000911
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000911
1020	CDK5, PSSALRE	cyclin-dependent kinase 5 (EC:2.7.11.22)	C00000911
1022	CDK7, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15	cyclin-dependent kinase 7 (EC:2.7.11.23 2.7.11.22)	C00000911
1025	CDK9, C-2k, CDC2L4, CTK1, PITALRE, TAK	cyclin-dependent kinase 9 (EC:2.7.11.23 2.7.11.22)	C00000911
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000911
1113	CHGA, CGA	chromogranin A (parathyroid secretory protein 1)	C00000911
1114	CHGB, SCG1	chromogranin B (secretogranin 1)	C00000911
23418	CRB1, LCA8, RP12	crumbs homolog 1 (Drosophila)	C00000911
1643	DDB2, DDBB, UV-DDB2	damage-specific DNA binding protein 2, 48kDa	C00000911
1981	EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18	eukaryotic translation initiation factor 4 gamma, 1	C00000911
6004	RGS16, A28-RGS14, A28-RGS14P, RGS-R	regulator of G-protein signaling 16	C00000094
5774	PTPN3, PTP-H1, PTPH1	protein tyrosine phosphatase, non-receptor type 3 (EC:3.1.3.48)	C00000094
2176	FANCC, FA3, FAC, FACC	Fanconi anemia, complementation group C	C00000911
2188	FANCF, FAF	Fanconi anemia, complementation group F	C00000911
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00000911
5782	PTPN12, PTP-PEST, PTPG1	protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48)	C00000094
2701	GJA4, CX37	gap junction protein, alpha 4, 37kDa	C00000911
2702	GJA5, ATFB11, CX40	gap junction protein, alpha 5, 40kDa	C00000911
2879	GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx	glutathione peroxidase 4 (EC:1.11.1.12)	C00000911
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00000911
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000911
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00000911
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00000911
3485	IGFBP2, IBP2, IGF-BP53	insulin-like growth factor binding protein 2, 36kDa	C00000911
9360	PPIG, CARS-Cyp, CYP, SCAF10, SRCyp	peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8)	C00000094
3716	JAK1, JAK1A, JAK1B, JTK3	Janus kinase 1 (EC:2.7.10.2)	C00000911
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00000094
3796	KIF2A, CDCBM3, HK2, KIF2	kinesin heavy chain member 2A	C00000911
3838	KPNA2, IPOA1, QIP2, RCH1, SRP1alpha	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	C00000911
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00000911
3988	LIPA, CESD, LAL	lipase A, lysosomal acid, cholesterol esterase (EC:3.1.1.13)	C00000911
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00000911
5605	MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2	mitogen-activated protein kinase kinase 2 (EC:2.7.12.2)	C00000911
6416	MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1	mitogen-activated protein kinase kinase 4 (EC:2.7.12.2)	C00000911
5608	MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3	mitogen-activated protein kinase kinase 6 (EC:2.7.12.2)	C00000911
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00000911
8544	PIR	pirin (iron-binding nuclear protein) (EC:1.13.11.24)	C00000094
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000911
4247	MGAT2, CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143)	C00000911
100507436	MICA, MIC-A, PERB11.1	MHC class I polypeptide-related sequence A	C00000911
4292	MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1	mutL homolog 1	C00000911
4436	MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2	mutS homolog 2	C00000911
2956	MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160	mutS homolog 6	C00000911
440	ASNS, TS11	asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)	C00000094
8021	NUP214, CAIN, CAN, D9S46E, N214, p250	nucleoporin 214kDa	C00000911
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00000911
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00000911
10111	RAD50, NBSLD, RAD502, hRad50	RAD50 homolog (S. cerevisiae)	C00000911
8045	RASSF7, C11orf13, HRAS1, HRC1	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	C00000911
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000911
5962	RDX, DFNB24	radixin	C00000911
6195	RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)	C00000911
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00000911
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00000911
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00000911
6414	SEPP1, SELP, SeP	selenoprotein P, plasma, 1	C00000911
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00000911
8243	SMC1A, CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB	structural maintenance of chromosomes 1A	C00000911
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00000911
9818	NUPL1, PRO2463	nucleoporin like 1	C00000094
7980	TFPI2, PP5, REF1, TFPI-2	tissue factor pathway inhibitor 2	C00000911
7039	TGFA, TFGA	transforming growth factor, alpha	C00000911
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00000911
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00000911
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00000094
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000911
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000911
7415	VCP, ALS14, IBMPFD, IBMPFD1, TERA, p97	valosin containing protein (EC:3.6.4.6)	C00000911
7485	WRB, CHD5	tryptophan rich basic protein	C00000911
7697	ZNF138, pHZ-32	zinc finger protein 138	C00000911
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00001497
116	ADCYAP1, PACAP	adenylate cyclase activating polypeptide 1 (pituitary)	C00001497
9370	ADIPOQ, ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28	adiponectin, C1Q and collagen domain containing	C00001497
153	ADRB1, ADRB1R, B1AR, BETA1AR, RHR	adrenoceptor beta 1	C00001497
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001497
155	ADRB3, BETA3AR	adrenoceptor beta 3	C00001497
250	ALPP, ALP, PALP, PLAP, PLAP-1	alkaline phosphatase, placental (EC:3.1.3.1)	C00001497
551	AVP, ADH, ARVP, AVP-NPII, AVRP, VP	arginine vasopressin	C00001497
554	AVPR2, ADHR, DI1, DIR, DIR3, NDI, V2R	arginine vasopressin receptor 2	C00001497
796	CALCA, CALC1, CGRP, CGRP-I, CGRP1, CT, KC	calcitonin-related polypeptide alpha	C00001497
10498	CARM1, PRMT4	coactivator-associated arginine methyltransferase 1 (EC:2.1.1.125)	C00001497
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00001497
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00001497
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00001497
1082	CGB, CGB3, CGB5, CGB7, CGB8, hCGB	chorionic gonadotropin, beta polypeptide	C00001497
1268	CNR1, CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR	cannabinoid receptor 1 (brain)	C00001497
1269	CNR2, CB-2, CB2, CX5	cannabinoid receptor 2 (macrophage)	C00001497
1387	CREBBP, CBP, KAT3A, RSTS	CREB binding protein (EC:2.3.1.48)	C00001497
1392	CRH, CRF	corticotropin releasing hormone	C00001497
1394	CRHR1, CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRH-R1h, CRHR, CRHR1L, CRHR1f	corticotropin releasing hormone receptor 1	C00001497
1440	CSF3, C17orf33, CSF3OS, GCSF, G-CSF	colony stimulating factor 3 (granulocyte)	C00001497
1584	CYP11B1, CPN1, CYP11B, FHI, P450C11	cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4)	C00001497
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00001497
27185	DISC1, C1orf136, SCZD9	disrupted in schizophrenia 1	C00001497
22943	DKK1, DKK-1, SK	dickkopf WNT signaling pathway inhibitor 1	C00001497
1812	DRD1, DADR, DRD1A	dopamine receptor D1	C00001497
1813	DRD2, D2DR, D2R	dopamine receptor D2	C00001497
2150	F2RL1, GPR11, PAR2	coagulation factor II (thrombin) receptor-like 1	C00001497
2488	FSHB	follicle stimulating hormone, beta polypeptide	C00001497
2668	GDNF, ATF1, ATF2, HFB1-GDNF, HSCR3	glial cell derived neurotrophic factor	C00001497
2778	GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH	GNAS complex locus	C00001497
338442	HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g	hydroxycarboxylic acid receptor 2	C00001497
8843	HCAR3, GPR109B, HCA3, HM74, PUMAG, Puma-g	hydroxycarboxylic acid receptor 3	C00001497
3269	HRH1, H1-R, hisH1	histamine receptor H1	C00001497
3274	HRH2, H2R	histamine receptor H2	C00001497
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00001497
3350	HTR1A, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	C00001497
3351	HTR1B, 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	C00001497
3363	HTR7, 5-HT7	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled	C00001497
3592	IL12A, CLMF, IL-12A, NFSK, NKSF1, P35	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	C00001497
3593	IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	C00001497
10681	GNB5, GB5	guanine nucleotide binding protein (G protein), beta 5	C00000094
694	BTG1	B-cell translocation gene 1, anti-proliferative	C00000094
3624	INHBA, EDF, FRP	inhibin, beta A	C00001497
3952	LEP, LEPD, OB, OBS	leptin	C00001497
3972	LHB, CGB4, LSH-B, hLHB	luteinizing hormone beta polypeptide	C00001497
3973	LHCGR, HHG, LCGR, LGR2, LH/CG-R, LH/CGR, LHR, LHRHR, LSH-R, ULG5	luteinizing hormone/choriogonadotropin receptor	C00001497
3991	LIPE, HSL, LHS	lipase, hormone-sensitive (EC:3.1.1.79)	C00001497
4158	MC2R, ACTHR	melanocortin 2 receptor (adrenocorticotropic hormone)	C00001497
54539	NDUFB11, CI-ESSS, ESSS, NP17.3, Np15, P17.3	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa	C00001497
4988	OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM	opioid receptor, mu 1	C00001497
10846	PDE10A, HSPDE10A	phosphodiesterase 10A (EC:3.1.4.35 3.1.4.17)	C00001497
50940	PDE11A, PPNAD2	phosphodiesterase 11A (EC:3.1.4.35 3.1.4.17)	C00001497
5150	PDE7A, HCP1, PDE7	phosphodiesterase 7A (EC:3.1.4.17)	C00001497
27115	PDE7B, bA472E5.1	phosphodiesterase 7B (EC:3.1.4.17)	C00001497
5151	PDE8A, HsT19550	phosphodiesterase 8A (EC:3.1.4.17)	C00001497
8622	PDE8B, ADSD, PPNAD3	phosphodiesterase 8B (EC:3.1.4.17)	C00001497
5152	PDE9A, HSPDE9A2	phosphodiesterase 9A (EC:3.1.4.35)	C00001497
5617	PRL	prolactin	C00001497
84432	PROK1, EGVEGF, PK1, PRK1	prokineticin 1	C00001497
5739	PTGIR, IP, PRIPR	prostaglandin I2 (prostacyclin) receptor (IP)	C00001497
5744	PTHLH, BDE2, HHM, PLP, PTHR, PTHRP	parathyroid hormone-like hormone	C00001497
5908	RAP1B, K-REV, RAL1B	RAP1B, member of RAS oncogene family	C00001497
9376	SLC22A8, OAT3	solute carrier family 22 (organic anion transporter), member 8	C00001497
6518	SLC2A5, GLUT-5, GLUT5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	C00001497
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00001497
7252	TSHB, TSH-B, TSH-BETA	thyroid stimulating hormone, beta	C00001497
7253	TSHR, CHNG1, LGR3, hTSHR-I	thyroid stimulating hormone receptor	C00001497
7432	VIP, PHM27	vasoactive intestinal peptide	C00001497
7434	VIPR2, C16DUPq36.3, DUP7q36.3, PACAP-R-3, PACAP-R3, VIP-R-2, VPAC2, VPAC2R, VPCAP2R	vasoactive intestinal peptide receptor 2	C00001497
7474	WNT5A, hWNT5A	wingless-type MMTV integration site family, member 5A	C00001497
124	ADH1A, ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1)	C00000919
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00000919
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00000919
8659	ALDH4A1, ALDH4, P5CD, P5CDh	aldehyde dehydrogenase 4 family, member A1 (EC:1.2.1.88)	C00000919
287	ANK2, ANK-2, LQT4, brank-2	ankyrin 2, neuronal	C00000919
288	ANK3, ANKYRIN-G, MRT37	ankyrin 3, node of Ranvier (ankyrin G)	C00000919
427	ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME	N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23)	C00000919
51665	ASB1, ASB-1	ankyrin repeat and SOCS box containing 1	C00000919
140462	ASB9	ankyrin repeat and SOCS box containing 9	C00000919
9531	BAG3, BAG-3, BIS, CAIR-1, MFM6	BCL2-associated athanogene 3	C00000919
9530	BAG4, BAG-4, SODD	BCL2-associated athanogene 4	C00000919
9529	BAG5, BAG-5	BCL2-associated athanogene 5	C00000919
581	BAX, BCL2L4	BCL2-associated X protein	C00000919
53630	BCMO1, BCDO, BCDO1, BCMO, BCO, BCO1	beta-carotene 15,15'-monooxygenase 1 (EC:1.14.99.36)	C00000919
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000919
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00000919
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00000919
9071	CLDN10, CPETRL3, OSP-L	claudin 10	C00000919
51208	CLDN18, SFTA5, SFTPJ	claudin 18	C00000919
1277	COL1A1, OI4	collagen, type I, alpha 1	C00000919
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00000919
1284	COL4A2, ICH, POREN2	collagen, type IV, alpha 2	C00000919
8738	CRADD, MRT34, RAIDD	CASP2 and RIPK1 domain containing adaptor with death domain	C00000919
1508	CTSB, APPS, CPSB	cathepsin B (EC:3.4.22.1)	C00000919
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00000919
6372	CXCL6, CKA-3, GCP-2, GCP2, SCYB6	chemokine (C-X-C motif) ligand 6	C00000919
4283	CXCL9, CMK, Humig, MIG, SCYB9, crg-10	chemokine (C-X-C motif) ligand 9	C00000919
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00000919
1592	CYP26A1, CP26, CYP26, P450RAI, P450RAI1	cytochrome P450, family 26, subfamily A, polypeptide 1 (EC:1.14.-.-)	C00000919
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000919
64816	CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43 (EC:1.14.14.1)	C00000919
1746	DLX2, TES-1, TES1	distal-less homeobox 2	C00000919
1748	DLX4, BP1, DLX7, DLX8, DLX9	distal-less homeobox 4	C00000919
2068	ERCC2, COFS2, EM9, TTD, XPD	excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12)	C00000919
23017	FAIM2, LFG, LFG2, NGP35, NMP35, TMBIM2	Fas apoptotic inhibitory molecule 2	C00000919
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00000919
3169	FOXA1, HNF3A, TCF3A	forkhead box A1	C00000919
2627	GATA6	GATA binding protein 6	C00000919
2633	GBP1	guanylate binding protein 1, interferon-inducible	C00000919
81025	GJA9, CX58, CX59, GJA10	gap junction protein, alpha 9, 59kDa	C00000919
373156	GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1	glutathione S-transferase kappa 1 (EC:2.5.1.18)	C00000919
2946	GSTM2, GST4, GSTM, GSTM2-2, GTHMUS	glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18)	C00000919
2948	GSTM4, GSTM4-4, GTM4	glutathione S-transferase mu 4 (EC:2.5.1.18)	C00000919
2949	GSTM5, GSTM5-5, GTM5	glutathione S-transferase mu 5 (EC:2.5.1.18)	C00000919
2954	GSTZ1, GSTZ1-1, MAAI, MAI	glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2)	C00000919
3204	HOXA7, ANTP, HOX1, HOX1.1, HOX1A	homeobox A7	C00000919
3216	HOXB6, HOX2, HOX2B, HU-2, Hox-2.2	homeobox B6	C00000919
3226	HOXC10, HOX3I	homeobox C10	C00000919
3448	IFNA14, IFN-alphaH, LEIF2H	interferon, alpha 14	C00000919
3449	IFNA16, IFN-alphaO	interferon, alpha 16	C00000919
3451	IFNA17, IFN-alphaI, IFNA, INFA, LEIF2C1	interferon, alpha 17	C00000919
3442	IFNA5, IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF_G	interferon, alpha 5	C00000919
3394	IRF8, H-ICSBP, ICSBP, ICSBP1, IRF-8	interferon regulatory factor 8	C00000919
50805	IRX4, IRXA3	iroquois homeobox 4	C00000919
3688	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	C00000919
3691	ITGB4, CD104	integrin, beta 4	C00000919
3875	KRT18, CYK18, K18	keratin 18	C00000919
3880	KRT19, CK19, K19, K1CS	keratin 19	C00000919
3849	KRT2, CK-2e, K2e, KRT2A, KRT2E, KRTE	keratin 2	C00000919
7127	TNFAIP2, B94, EXOC3L3	tumor necrosis factor, alpha-induced protein 2	C00000094
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00000919
8022	LHX3, CPHD3, LIM3, M2-LHX3	LIM homeobox 3	C00000919
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000919
4153	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD	mannose-binding lectin (protein C) 2, soluble	C00000919
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00000919
4212	MEIS2, HsT18361, MRG1	Meis homeobox 2	C00000919
4222	MEOX1, KFS2, MOX1	mesenchyme homeobox 1	C00000919
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00000919
3110	MNX1, HB9, HLXB9, HOXHB9, SCRA1	motor neuron and pancreas homeobox 1	C00000919
4439	MSH5, G7, MUTSH5, NG23	mutS homolog 5	C00000919
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00000919
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000919
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00000919
5098	PCDHGC3, PC43, PCDH-GAMMA-C3, PCDH2	protocadherin gamma subfamily C, 3	C00000919
5359	PLSCR1, MMTRA1B	phospholipid scramblase 1	C00000919
57048	PLSCR3	phospholipid scramblase 3	C00000919
57088	PLSCR4, TRA1	phospholipid scramblase 4	C00000919
10635	RAD51AP1, PIR51	RAD51 associated protein 1	C00000919
5892	RAD51D, BROVCA4, R51H3, RAD51L3, TRAD	RAD51 paralog D	C00000919
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00000919
5915	RARB, HAP, NR1B2, RRB2	retinoic acid receptor, beta	C00000919
5918	RARRES1, LXNL, TIG1	retinoic acid receptor responder (tazarotene induced) 1	C00000919
5950	RBP4, RDCCAS	retinol binding protein 4, plasma	C00000919
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00000919
949	SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1	scavenger receptor class B, member 1	C00000919
4990	SIX6, MCOPCT2, OPTX2, Six9	SIX homeobox 6	C00000919
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000919
9517	SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a	serine palmitoyltransferase, long chain base subunit 2 (EC:2.3.1.50)	C00000919
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00000919
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00000919
7047	TGM4, TGP, hTGP	transglutaminase 4 (EC:2.3.2.13)	C00000919
3604	TNFRSF9, 4-1BB, CD137, CDw137, ILA	tumor necrosis factor receptor superfamily, member 9	C00000919
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00000919
10190	TXNDC9, APACD, PHLP3	thioredoxin domain containing 9	C00000919
7517	XRCC3, CMM6	X-ray repair complementing defective repair in Chinese hamster cells 3	C00000919

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