Species

KNApSAcK Entry

Organism name Ligusticum scoticum
Genus Ligusticum
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ligusticum scoticum
Linked NCBI taxonomy ID 49554
Linked level species

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002737 External link 512 Dillapiole
CHEMBL470874
C059115
1 / 0 / 0 No. 1917 No. 6
C00002762 External link 512 Myristicin
CHEMBL481044
C005246
6 / 4 / 2 2 / 0 No. 1917 No. 6

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00002762 4 / 1
P06746 DNA polymerase beta Enzyme C00002737 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00002762 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002762 0 / 0
O75496 Geminin Unclassified protein C00002762 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002762 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002762 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00002762
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00002762

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (2)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)