PCIDB

Beilschmiedia miersii

Species

KNApSAcK Entry

Organism name Beilschmiedia miersii
Genus Beilschmiedia
Family Lauraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Beilschmiedia miersii
Linked NCBI taxonomy ID 263808
Linked level species

Family

Family in NCBI taxonomy Lauraceae
ID 3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00005501 External link 512 Azaleatin 3-glucuronide
No. 2 No. 15
C00005376 External link 512 Miquelianin
/ Quercetin 3-O-beta-D-glucuronide
CHEMBL520546
CHEMBL1506682
23 / 30 / 21 No. 2 No. 15
C00005140 External link 512 Afzelin
/ Kaempferol 3-O-alpha-rhamnoside
/ Kaempferol 3-O-alpha-L-rhamnopyranoside
CHEMBL240528
CHEMBL515798
C477954
4 / 2 / 2 No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00004633 External link 512 Azaleatin
CHEMBL470848
2 / 2 / 1 No. 3 No. 15
C00002773 External link 512 Sarisan
/ Asaricin
/ 1-Allyl-2-methoxy-4,5-methylene-dioxybenzene
C056048
No. 1917 No. 6

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00005374 C00005376 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005374 C00005376 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005374 C00005376 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005374 C00005376 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005374 C00005376 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00005374 C00005376 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005374 C00005376 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005374 C00005376 1 / 1
P39748 Flap endonuclease 1 Enzyme C00005374 C00005376 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00005376 0 / 0
P04792 Heat shock protein beta-1 Unclassified protein C00004633 2 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005376 1 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00005140 1 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005374 1 / 1
P15121 Aldose reductase Enzyme C00005374 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00005376 7 / 3
P02545 Prelamin-A/C Unclassified protein C00005376 11 / 10
P07237 Protein disulfide-isomerase Enzyme C00005374 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00005376 3 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00005376 0 / 0
P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] Enzyme C00005140 0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00005376 0 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005140 0 / 1
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00005140 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005376 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005376 1 / 1
P06746 DNA polymerase beta Enzyme C00005376 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00005376 4 / 3
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00005376 0 / 0
Q9NPH5 NADPH oxidase 4 Enzyme C00004633 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00005376 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00005376 2 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005374

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (35)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#606595 Charcot-marie-tooth disease, axonal, type 2f; cmt2f P04792
#114500 Colorectal cancer; crc Q14191
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#608634 Neuronopathy, distal hereditary motor, type iib; hmn2b P04792
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#275210 Restrictive dermopathy, lethal P02545
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (25)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00856 Distal hereditary motor neuropathies (dHMN) P04792 (related)
H00213 Hypophosphatasia P05186 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00192 Xanthinuria P47989 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00107 Other well-defined immunodeficiency syndromes P98170 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D010146 Pain C00005374