PCIDB

KNApSAcK Metabolite C00005376

Metabolite

KNApSAcK Entry

id C00005376
Name Miquelianin / Quercetin 3-O-beta-D-glucuronide
CAS RN 22688-79-5
Standard InChI InChI=1S/C21H18O13/c22-7-4-10(25)12-11(5-7)32-17(6-1-2-8(23)9(24)3-6)18(13(12)26)33-21-16(29)14(27)15(28)19(34-21)20(30)31/h1-5,14-16,19,21-25,27-29H,(H,30,31)/t14?,15-,16?,19-,21+/m0/s1
Standard InChI (Main Layer) InChI=1S/C21H18O13/c22-7-4-10(25)12-11(5-7)32-17(6-1-2-8(23)9(24)3-6)18(13(12)26)33-21-16(29)14(27)15(28)19(34-21)20(30)31/h1-5,14-16,19,21-25,27-29H,(H,30,31)

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 2

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL520546 CHEMBL1506682

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
asterids 9
rosids 8
Liliopsida 4
eudicotyledons 3
Euphyllophyta 1
Magnoliophyta 1

Family (Top 10)

family name count
Apiaceae 3
Zingiberaceae 3
Polygonaceae 3
Asteraceae 3
Geraniaceae 2
Campanulaceae 1
Hypericaceae 1
Malvaceae 1
Salicaceae 1
Onagraceae 1

List (26)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Adiantum spp. 13817 Pteridaceae Euphyllophyta Viridiplantae
Alpinia elatior 4642 Zingiberaceae Liliopsida Viridiplantae
Anethum sowa 40921 Apiaceae asterids Viridiplantae
Arnica chamissonis 436195 Asteraceae asterids Viridiplantae
Beilschmiedia miersii 263808 Lauraceae Magnoliophyta Viridiplantae
Campanula glomerata L. 82281 Campanulaceae asterids Viridiplantae
Cautleya spicata 105370 Zingiberaceae Liliopsida Viridiplantae
Eriogonum nudum 430753 Polygonaceae eudicotyledons Viridiplantae
Euphorbia spp. 3977 Euphorbiaceae rosids Viridiplantae
Foeniculum vulgare 48038 Apiaceae asterids Viridiplantae
Fuchsia fulgens 253484 Onagraceae rosids Viridiplantae
Gaultheria miqueliana 95633 Ericaceae asterids Viridiplantae
Geranium dissectum 326028 Geraniaceae rosids Viridiplantae
Gutierrezia wrightii 71047 Asteraceae asterids Viridiplantae
Hedychium thyrsiforme 110726 Zingiberaceae Liliopsida Viridiplantae
Hypericum perforatum 65561 Hypericaceae rosids Viridiplantae
Monsonia spp. 21556 Geraniaceae rosids Viridiplantae
Orlaya spp. Lasthenia spp. 40860 Apiaceae asterids Viridiplantae
Philydrum lanuginosum 44976 Philydraceae Liliopsida Viridiplantae
Polygonum hydropiper L. 46901 Polygonaceae eudicotyledons Viridiplantae
Polygonum viviparum 371026 Polygonaceae eudicotyledons Viridiplantae
Populus grandidentata 482945 Salicaceae rosids Viridiplantae
Psidium guaijava 120289 Myrtaceae rosids Viridiplantae
Salvia blepharophylla 933122 Lamiaceae asterids Viridiplantae
Stephanodoria tomentella 4210 Asteraceae asterids Viridiplantae
Theobroma grandiflorum 108881 Malvaceae rosids Viridiplantae

Human Protein / Gene in interaction

23 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1506682 CHEMBL1738312 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL1506682 CHEMBL1614079 (1)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL1506682 CHEMBL1614076 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1506682 CHEMBL1794585 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL1506682 CHEMBL1614544 (1)
11 / 10
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL1506682 CHEMBL1614166 (1)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL1506682 CHEMBL1614458 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL1506682 CHEMBL1794486 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1506682 CHEMBL2114810 (1)
7 / 3
Q9Y253 DNA polymerase eta Enzyme CHEMBL1506682 CHEMBL1794569 (1)
1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL1506682 CHEMBL1738087 (1) CHEMBL1738192 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL1506682 CHEMBL1738668 (1)
3 / 1
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1506682 CHEMBL1794401 (1)
0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme CHEMBL1506682 CHEMBL1738185 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1506682 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1506682 CHEMBL1737991 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL1506682 CHEMBL1614211 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL1506682 CHEMBL1614421 (1)
4 / 3
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1506682 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL1506682 CHEMBL1613914 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL1506682 CHEMBL1738442 (1)
0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL1506682 CHEMBL2114738 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL1506682 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (30)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc Q14191
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#275210 Restrictive dermopathy, lethal P02545
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (21)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00213 Hypophosphatasia P05186 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)