| Organism name | Adiantum spp. |
|---|---|
| Genus | Adiantum |
| Family | Pteridaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Adiantum |
|---|---|
| Linked NCBI taxonomy ID | 13817 |
| Linked level | genus |
| Family in NCBI taxonomy | Pteridaceae |
|---|---|
| ID | 13819 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Euphyllophyta |
|---|---|
| ID | 78536 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00006620
|
Gesnerin
|
No. 2 | No. 15 |
|
||||
|
C00005376
|
Miquelianin
/ Quercetin 3-O-beta-D-glucuronide |
CHEMBL520546
CHEMBL1506682 |
23 / 30 / 21 | No. 2 | No. 15 |
|
||
|
C00003784
|
Rhodoxanthin
|
C038054
|
No. 26 | No. 59 |
|
|||
|
C00000983
|
Naringin
|
CHEMBL451532
CHEMBL451512 CHEMBL1742953 CHEMBL1970019 |
C005274
|
18 / 12 / 6 | 12 / 4 | No. 48 | No. 14 |
|
|
C00006610
|
Apigeninidin
|
CHEMBL1197890
|
C104027
|
No. 71 | No. 15 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000983 C00005376 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000983 C00005376 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00005376 | 3 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00005376 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000983 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00005376 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00005376 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00005376 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00005376 | 11 / 10 |
| P08183 | Multidrug resistance protein 1 | drug | C00000983 | 1 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005376 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00005376 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00005376 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000983 | 0 / 0 |
| P46721 | Solute carrier organic anion transporter family member 1A2 | Unclassified protein | C00000983 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000983 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00005376 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00005376 | 1 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00005376 | 0 / 0 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000983 | 1 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00000983 | 1 / 2 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000983 | 3 / 0 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000983 | 1 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000983 | 2 / 2 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00005376 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005376 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00005376 | 0 / 0 |
| P61088 | Ubiquitin-conjugating enzyme E2 N | Enzyme | C00000983 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005376 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000983 | 5 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00005376 | 4 / 3 |
| Q9Y251 | Heparanase | Enzyme | C00000983 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005376 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00005376 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000983 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000983 | 1 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005376 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00005376 | 2 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000983 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000983
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000983
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000983
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000983
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000983
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000983
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000983
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000983
|
| 8772 | FADD, MORT1 | Fas (TNFRSF6)-associated via death domain |
C00000983
|
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00000983
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000983
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000983
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|