Morinda citrifolia

• Index
• Plant Species
• Metabolite list (30)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Morinda citrifolia
Genus	Morinda
Family	Rubiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Morinda citrifolia
Linked NCBI taxonomy ID	43522
Linked level	species

Family

Family in NCBI taxonomy	Rubiaceae
ID	24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (30)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005169	Nicotiflorin / Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside	CHEMBL431610 CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691		22 / 10 / 12		No. 1	No. 15
C00005413	Rutin / Birutan / 3-Rutinosylquercetin / Quercetin 3-O-rutinoside / (+)-Quercetin 3-O-rutinoside / Quercetin 3-O-beta-rutinoside / (+)-Quercetin 3-O-beta-rutinoside / 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside / Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside	CHEMBL32579 CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989	D012431	25 / 18 / 16	29 / 8	No. 1	No. 15
C00004215	Apigenin 5,7-dimethyl ether 4'-galactoside					No. 2	No. 15
C00005374	Quercetin	CHEMBL82242 CHEMBL479232 CHEMBL1437696	C012526	14 / 2 / 2	2 / 1	No. 2	No. 15
C00000587	(-)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862		7 / 5 / 6		No. 38	No. 21
C00038191	1-Hydroxyanthraquinone	CHEMBL501834	C061208	1 / 0 / 1		No. 41	No. 62
C00002862	Rubiadin / 1,3-Dihydroxy-2-methyl-9,10-anthraquinone	CHEMBL251251	C072500			No. 41	No. 62
C00002844	Morindone					No. 41	No. 62
C00002786	Alizarin 2-methyl ether / 1-Hydroxy-2-methoxyanthraquinone	CHEMBL451977		6 / 9 / 11		No. 41	No. 62
C00031546	6-Hydroxyrubiadin / 1,3,6-Trihydroxy-2-methylanthraquinone / 2-Methyl-1,3,6-trihydroxyanthraquinone / 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone	CHEMBL251491				No. 41	No. 62
C00002785	Alizarin	CHEMBL55814	C010078	44 / 36 / 35	12 / 0	No. 41	No. 62
C00038228	2-Hydroxy-3-(hydroxymethyl)anthraquinone	CHEMBL251490				No. 41	No. 62
C00040332	Soranjidiol		C569240			No. 41	No. 62
C00030089	Damnacanthol	CHEMBL522932				No. 41	No. 62
C00031525	Lucidin 3-methyl ether / 1-Hydroxy-2-hydroxymethyl-3-methoxyanthraquinone / 1-Hydroxy-2-(hydroxymethyl)-3-methoxyanthraquinone					No. 41	No. 62
C00042396	Citrifolinin B epimer b	CHEMBL518691 CHEMBL517315				No. 56	No. 36
C00042395	Citrifolinin B epimer a	CHEMBL518691 CHEMBL517315				No. 56	No. 36
C00004565	Kaempferol / Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL150	C006552	76 / 69 / 87	86 / 8	No. 71	No. 15
C00003072	Asperuloside	CHEMBL461910 CHEMBL1965021	C077956	1 / 0 / 0		No. 100	No. 36
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00042457	Dehydromethoxygaertneroside / (-)-Dehydromethoxygaertneroside	CHEMBL446254				No. 774
C00039452	Isoscopoletin	CHEMBL390320		12 / 3 / 8		No. 864	No. 25
C00002499	Scopoletin	CHEMBL71851	D012603	48 / 37 / 34	9 / 0	No. 864	No. 25
C00002683	Vanillin	CHEMBL13883		18 / 8 / 9		No. 1003
C00042470	D-Glucose	CHEMBL1206211	D005947		183 / 47	No. 1384
C00039795	Morintrifolin A					No. 1795
C00039796	Morintrifolin B					No. 1795
C00031592	Americanin / Americanin A	CHEMBL482240	C055022			No. 1955
C00042736	Methyl beta-D-fructofuranoside / (-)-Methyl beta-D-fructofuranoside	CHEMBL450037 CHEMBL500884	C099954			No. 2228
C00042440	Cytidine	CHEMBL6592 CHEMBL78 CHEMBL803 CHEMBL95606 CHEMBL1315342 CHEMBL2028065 CHEMBL2092816 CHEMBL2093067	D003562	115 / 62 / 54	2 / 1	No. 2366

Human Protein / Gene in interactions

225 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002499 C00004565 C00005169 C00005374 C00005413 C00039452	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002785 C00004565 C00005169 C00005374 C00005413 C00042440	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000587 C00002499 C00004565 C00005413 C00039452 C00042440	0 / 3
P10636	Microtubule-associated protein tau	Unclassified protein	C00002785 C00002786 C00004565 C00005413 C00042440	4 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002499 C00002785 C00004565 C00005413 C00042440	0 / 1
Q99700	Ataxin-2	Unclassified protein	C00002499 C00002785 C00004565 C00005169 C00042440	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002499 C00002683 C00002785 C00004565 C00005374	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002499 C00002785 C00004565 C00005374 C00005413	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002785 C00005169 C00005374 C00005413 C00039452	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002499 C00002785 C00002786 C00004565	1 / 2
O00255	Menin	Unclassified protein	C00002499 C00002785 C00002786 C00004565	2 / 5
Q9Y253	DNA polymerase eta	Enzyme	C00002785 C00004565 C00005169 C00005374	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00002785 C00004565 C00005169 C00005374	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002785 C00004565 C00005169 C00005374	0 / 0
O75496	Geminin	Unclassified protein	C00002499 C00002785 C00005169 C00042440	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002499 C00002785 C00005169 C00042440	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00002499 C00004565 C00005413 C00042440	1 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000587 C00002499 C00004565 C00039452	0 / 0
P03372	Estrogen receptor	NR3A1	C00002785 C00004565 C00005413 C00042440	1 / 1
P15121	Aldose reductase	Enzyme	C00002499 C00004565 C00005374 C00039452	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002499 C00002683 C00002785 C00004565	2 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002499 C00002785 C00004565 C00005413	3 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00004565 C00005169 C00005374 C00042440	0 / 0
P06746	DNA polymerase beta	Enzyme	C00005169 C00005413 C00019308	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002499 C00004565 C00042440	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002785 C00004565 C00005413	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002785 C00005413 C00042440	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002499 C00004565 C00042440	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002499 C00005169 C00005413	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002683 C00005169 C00005374	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002786 C00005169 C00005413	1 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002683 C00004565 C00042440	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002785 C00005169 C00042440	1 / 4
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002499 C00002683 C00002785	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002785 C00005169 C00042440	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002499 C00004565 C00042440	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002499 C00002683 C00002785	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002499 C00039452 C00042440	1 / 2
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002499 C00002785 C00005169	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002499 C00005413 C00042440	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002785 C00003072 C00042440	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002499 C00004565 C00042440	1 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002499 C00004565 C00042440	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002683 C00004565	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00004565 C00042440	11 / 10
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002499 C00039452	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002499 C00002785	5 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002785 C00004565	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002499 C00039452	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000587 C00004565	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002683 C00002785	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002499 C00002683	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005413 C00042440	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002499 C00002785	0 / 0
P29466	Caspase-1	C14	C00002499 C00042440	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004565 C00005413	2 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002499 C00039452	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002499 C00039452	0 / 1
P04062	Glucosylceramidase	Enzyme	C00002499 C00004565	6 / 4
P10275	Androgen receptor	NR3C4	C00002683 C00004565	3 / 4
Q96RI1	Bile acid receptor	NR1H4	C00002683 C00004565	0 / 0
P06276	Cholinesterase	Hydrolase	C00004565 C00005413	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000587 C00004565	5 / 3
P14679	Tyrosinase	Oxidoreductase	C00004565 C00005413	4 / 2
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000587 C00004565	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00004565 C00042440	0 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00038191 C00042440	0 / 1
P48147	Prolyl endopeptidase	S9A	C00004565 C00005413	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00004565 C00042440	2 / 2
Q16637	Survival motor neuron protein	Unclassified protein	C00002785 C00042440	4 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00005169 C00005374	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00004565 C00042440	1 / 8
P11388	DNA topoisomerase 2-alpha	Isomerase	C00004565 C00005413	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002683 C00004565	1 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002499 C00002785	7 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00004565 C00042440	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00004565 C00005413	0 / 1
P49841	Glycogen synthase kinase-3 beta	Gsk	C00004565 C00019308	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002499 C00039452	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002499 C00019308	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00002785 C00042440	0 / 1
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00005413 C00042440	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002499 C00002785	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002785 C00004565	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002499 C00002785	3 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00004565 C00005413	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000587 C00004565	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002499 C00039452	1 / 2
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002499 C00002785	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00002785 C00005169	2 / 1
P07237	Protein disulfide-isomerase	Enzyme	C00005169 C00005374	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00042440	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00004565	1 / 1
P41968	Melanocortin receptor 3	Melanocortin receptor	C00042440	1 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002786	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00042440	0 / 0
Q9HA47	Uridine-cytidine kinase 1	Enzyme	C00042440	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00042440	1 / 1
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00042440	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00004565	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00042440	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00042440	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00042440	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00042440	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00042440	0 / 0
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00042440	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00042440	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00042440	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00042440	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00042440	1 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00042440	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00042440	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00042440	0 / 0
P08311	Cathepsin G	S1A	C00042440	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00042440	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00042440	1 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00002683	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00042440	0 / 0
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00004565	1 / 1
P03956	Interstitial collagenase	M10A	C00042440	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00042440	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00042440	2 / 0
Q04206	Transcription factor p65	Transcription Factor	C00002499	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00005169	2 / 3
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00004565	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00002683	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00004565	0 / 0
Q99816	Tumor susceptibility gene 101 protein	Unclassified protein	C00002785	0 / 0
P00734	Prothrombin	S1A	C00019308	4 / 2
Q00535	Cyclin-dependent kinase 5	Cdk5	C00004565	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00042440	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00042440	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00042440	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00042440	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00042440	2 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00042440	0 / 0
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00002683	1 / 1
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00042440	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00042440	1 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00004565	4 / 4
P21452	Substance-K receptor	Neurokinin receptor	C00042440	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00042440	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00042440	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00042440	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00042440	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00042440	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002499	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00004565	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00002785	2 / 0
P08183	Multidrug resistance protein 1	drug	C00004565	1 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00042440	1 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00004565	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00042440	2 / 1
P11309	Serine/threonine-protein kinase pim-1	Pim	C00004565	0 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00004565	1 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002683	0 / 0
Q99873	Protein arginine N-methyltransferase 1	Enzyme	C00002785	0 / 0
P04183	Thymidine kinase, cytosolic	Enzyme	C00042440	0 / 1
P27707	Deoxycytidine kinase	Enzyme	C00042440	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002786	1 / 1
Q9Y6Q9	Nuclear receptor coactivator 3	Enzyme	C00042440	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00004565	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000587	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00042440	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00042440	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00042440	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00042440	1 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00042440	1 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00042440	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00042440	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00042440	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00042440	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00042440	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00042440	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00042440	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00042440	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00042440	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00042440	1 / 1
P55210	Caspase-7	C14	C00002499	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00042440	0 / 1
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00004565	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00002683	1 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00042440	0 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00004565	1 / 1
O00142	Thymidine kinase 2, mitochondrial	Enzyme	C00042440	1 / 1
P10828	Thyroid hormone receptor beta	NR1A2	C00042440	3 / 1
P08047	Transcription factor Sp1	Unclassified protein	C00019308	0 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00002499	1 / 0
P14780	Matrix metalloproteinase-9	M10A	C00042440	2 / 2
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002499	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00042440	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00042440	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00042440	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00042440	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00042440	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00042440	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00042440	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00042440	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00042440	1 / 1
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00002683	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00004565	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00004565	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00042440	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00042440	0 / 0
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00002785	0 / 7
P08246	Neutrophil elastase	S1A	C00042440	2 / 1
Q14145	Kelch-like ECH-associated protein 1	Unclassified protein	C00002785	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00042440	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005169	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00042440	1 / 1
Q15788	Nuclear receptor coactivator 1	Enzyme	C00042440	0 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00004565	0 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00002499	1 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00002785	0 / 0
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00005374	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00004565	7 / 37
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00004565	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00004565	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00004565	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00004565	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00004565	0 / 0
P32320	Cytidine deaminase	Enzyme	C00042440	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00004565	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00042440	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002785	1 / 1

251 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002785 C00004565 C00005374 C00005413 C00042470
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00002785 C00004565 C00005374 C00005413
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00004565 C00005413 C00042470
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00004565 C00005413 C00042470
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00004565 C00005413 C00042470
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00004565 C00005413 C00042470
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00004565 C00005413 C00042470
581	BAX, BCL2L4	BCL2-associated X protein	C00004565 C00005413 C00042470
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00004565 C00005413 C00042470
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00004565 C00005413 C00042470
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004565 C00005413 C00042470
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00004565 C00005413 C00042470
7039	TGFA, TFGA	transforming growth factor, alpha	C00004565 C00005413 C00042470
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00002785 C00004565 C00042470
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00004565 C00005413 C00042470
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00004565 C00005413 C00042470
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00004565 C00005413 C00042470
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002499 C00002785 C00004565
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002499 C00002785 C00004565
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002499 C00002785 C00004565
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002499 C00002785 C00004565
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002499 C00002785 C00004565
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002499 C00004565
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002499 C00002785
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00005413 C00042470
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002785 C00004565
847	CAT	catalase (EC:1.11.1.6)	C00005413 C00042470
7352	UCP3, SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	C00004565 C00042470
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00004565 C00042470
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00005413 C00042470
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00005413 C00042470
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004565 C00042470
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00004565 C00042470
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00004565 C00042470
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00004565 C00042470
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00005413 C00042470
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00004565 C00042470
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00004565 C00042470
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00004565 C00042470
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00005413 C00042470
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00004565 C00042470
3667	IRS1, HIRS-1	insulin receptor substrate 1	C00005413 C00042470
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00004565 C00042470
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00005413 C00042470
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00004565 C00042470
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00005413 C00042470
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004565 C00042470
155184	SLC2A7, GLUT7	solute carrier family 2 (facilitated glucose transporter), member 7	C00042470
4297	KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS	lysine (K)-specific methyltransferase 2A (EC:2.1.1.43)	C00004565
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00004565
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00004565
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00004565
110357			C00004565
4502	MT2A, MT2	metallothionein 2A	C00004565
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00004565
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00004565
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00004565
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00004565
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00004565
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00004565
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00004565
5241	PGR, NR3C3, PR	progesterone receptor	C00004565
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00004565
8000	PSCA, PRO232	prostate stem cell antigen	C00004565
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00004565
6119	RPA3, REPA3	replication protein A3, 14kDa	C00004565
2810	SFN, YWHAS	stratifin	C00004565
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00004565
6773	STAT2, ISGF-3, P113, STAT113	signal transducer and activator of transcription 2, 113kDa	C00004565
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00004565
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004565
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00004565
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00004565
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00004565
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00004565
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00004565
7161	TP73, P73	tumor protein p73	C00004565
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00004565
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00004565
37618			C00004565
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00004565
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00004565
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00004565
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00004565
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00004565
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00004565
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00002785
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002785
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00004565
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00042440
9154	SLC28A1, CNT1, HCNT1	solute carrier family 28 (concentrative nucleoside transporter), member 1	C00042440
31	ACACA, ACAC, ACACAD, ACC, ACC1, ACCA	acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14)	C00042470
1636	ACE, ACE1, CD143, DCP, DCP1, ICH, MVCD3	angiotensin I converting enzyme (EC:3.4.15.1)	C00042470
59	ACTA2, AAT6, ACTSA, MYMY5	actin, alpha 2, smooth muscle, aorta	C00042470
60	ACTB, BRWS1, PS1TP5BP1	actin, beta	C00042470
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00004565
183	AGT, ANHU, SERPINA8	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	C00042470
185	AGTR1, AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R	angiotensin II receptor, type 1	C00042470
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00042470
219	ALDH1B1, ALDH5, ALDHX	aldehyde dehydrogenase 1 family, member B1 (EC:1.2.1.3)	C00042470
440	ASNS, TS11	asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)	C00042470
476	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)	C00042470
650	BMP2, BDA2, BMP2A	bone morphogenetic protein 2	C00042470
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00004565
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00042470
891	CCNB1, CCNB	cyclin B1	C00004565
929	CD14	CD14 molecule	C00042470
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00042470
634	CEACAM1, BGP, BGP1, BGPI	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	C00042470
1152	CKB, B-CK, CKBB	creatine kinase, brain (EC:2.7.3.2)	C00042470
1278	COL1A2, OI4	collagen, type I, alpha 2	C00042470
1490	CTGF, CCN2, HCS24, IGFBP8, NOV2	connective tissue growth factor	C00042470
1508	CTSB, APPS, CPSB	cathepsin B (EC:3.4.22.1)	C00042470
6376	CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin	chemokine (C-X3-C motif) ligand 1	C00042470
1535	CYBA, p22-PHOX	cytochrome b-245, alpha polypeptide	C00042470
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00042470
1616	DAXX, BING2, DAP6, EAP1	death-domain associated protein	C00042470
8527	DGKD, DGKdelta, dgkd-2	diacylglycerol kinase, delta 130kDa (EC:2.7.1.107)	C00042470
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00042470
1950	EGF, HOMG4, URG	epidermal growth factor	C00042470
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00042470
2021	ENDOG	endonuclease G	C00042470
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00042470
2194	FASN, FAS, OA-519, SDR27X1	fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39)	C00042470
26291	FGF21	fibroblast growth factor 21	C00042470
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00042470
2348	FOLR1, FBP, FOLR	folate receptor 1 (adult)	C00042470
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00042470
2538	G6PC, G6PC1, G6PT, GSD1, GSD1a	glucose-6-phosphatase, catalytic subunit (EC:3.1.3.9)	C00042470
2597	GAPDH, G3PD, GAPD	glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)	C00042470
2641	GCG, GLP1, GLP2, GRPP	glucagon	C00042470
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00042470
2697	GJA1, AVSD3, CMDR, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD	gap junction protein, alpha 1, 43kDa	C00042470
2720	GLB1, EBP, ELNR1, MPS4B	galactosidase, beta 1 (EC:3.2.1.23)	C00042470
26585	GREM1, CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2	gremlin 1, DAN family BMP antagonist	C00042470
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00042470
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00004565
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00042470
6927	HNF1A, HNF-1A, HNF1, IDDM20, LFB1, MODY3, TCF-1, TCF1	HNF1 homeobox A	C00042470
3172	HNF4A, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14	hepatocyte nuclear factor 4, alpha	C00042470
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00042470
3329	HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13	heat shock 60kDa protein 1 (chaperonin)	C00042470
3375	IAPP, DAP, IAP	islet amyloid polypeptide	C00042470
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00004565
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00004565
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00042470
3643	INSR, CD220, HHF5	insulin receptor (EC:2.7.10.1)	C00042470
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00004565
8660	IRS2, IRS-2	insulin receptor substrate 2	C00042470
3674	ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	C00042470
3690	ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	C00042470
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00042470
3778	KCNMA1, BKTM, KCa1.1, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, bA205K10.1, mSLO1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	C00042470
3779	KCNMB1, BKbeta1, K(VCA)beta, SLO-BETA, hbeta1, hslo-beta, k(VCA)beta-1, slo-beta-1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	C00042470
7071	KLF10, EGR-alpha, EGRA, TIEG, TIEG1	Kruppel-like factor 10	C00042470
54474	KRT20, CD20, CK-20, CK20, K20, KRT21	keratin 20	C00042470
3920	LAMP2, CD107b, LAMP-2, LAMPB, LGP110	lysosomal-associated membrane protein 2	C00042470
3945	LDHB, LDH-B, LDH-H, LDHBD, TRG-5	lactate dehydrogenase B (EC:1.1.1.27)	C00042470
3952	LEP, LEPD, OB, OBS	leptin	C00042470
3976	LIF, CDF, DIA, HILDA, MLPLI	leukemia inhibitory factor	C00042470
4023	LPL, HDLCQ11, LIPD	lipoprotein lipase (EC:3.1.1.34)	C00042470
389692	MAFA, RIPE3b1, hMafA	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	C00042470
4217	MAP3K5, ASK1, MAPKKK5, MEKK5	mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25)	C00042470
1432	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA	mitogen-activated protein kinase 14 (EC:2.7.11.24)	C00042470
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00042470
100314030			C00042470
387164			C00042470
406938	MIR146A, MIRN146, MIRN146A, miR-146a, miRNA146A	microRNA 146a	C00042470
406940	MIR148A, MIRN148, MIRN148A, hsa-mir-148	microRNA 148a	C00042470
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00042470
4323	MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS	matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80)	C00042470
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00042470
10135	NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN	nicotinamide phosphoribosyltransferase (EC:2.4.2.12)	C00042470
8775	NAPA, SNAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	C00042470
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00042470
57447	NDRG2, SYLD	NDRG family member 2	C00042470
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00042470
4825	NKX6-1, NKX6.1, NKX6A	NK6 homeobox 1	C00042470
4842	NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS	nitric oxide synthase 1 (neuronal) (EC:1.14.13.39)	C00042470
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00042470
8431	NR0B2, SHP, SHP1	nuclear receptor subfamily 0, group B, member 2	C00042470
7025	NR2F1, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1	nuclear receptor subfamily 2, group F, member 1	C00042470
26471	NUPR1, COM1, P8	nuclear protein, transcriptional regulator, 1	C00042470
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00042470
5033	P4HA1, P4HA	prolyl 4-hydroxylase, alpha polypeptide I (EC:1.14.11.2)	C00042470
51247	PAIP2, PAIP2A	poly(A) binding protein interacting protein 2	C00042470
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00042470
3651	PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1	pancreatic and duodenal homeobox 1	C00042470
5037	PEBP1, HCNP, HCNPpp, PBP, PEBP, PEBP-1, RKIP	phosphatidylethanolamine binding protein 1	C00042470
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00042470
5315	PKM, CTHBP, OIP3, PK3, PKM2, TCB, THBP1	pyruvate kinase, muscle (EC:2.7.1.40)	C00042470
5358	PLS3, BMND18, T-plastin	plastin 3	C00042470
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00042470
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00042470
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00042470
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00042470
5563	PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA	protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31)	C00042470
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00042470
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00042470
5621	PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30	prion protein	C00042470
5682	PSMA1, HC2, NU, PROS30	proteasome (prosome, macropain) subunit, alpha type, 1 (EC:3.4.25.1)	C00042470
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00042470
5935	RBM3, IS1-RNPL, RNPL	RNA binding motif (RNP1, RRM) protein 3	C00042470
239	ALOX12, 12-LOX, 12S-LOX, LOG12	arachidonate 12-lipoxygenase (EC:1.13.11.31)	C00004565
56729	RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1	resistin	C00042470
6206	RPS12, S12	ribosomal protein S12	C00042470
3921	RPSA, 37LRP, 67LR, LAMBR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, NEM/1CHD4, SA, lamR, p40	ribosomal protein SA	C00042470
6396	SEC13, D3S1231E, SEC13L1, SEC13R, npp-20	SEC13 homolog (S. cerevisiae)	C00042470
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00042470
6403	SELP, CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL	selectin P (granule membrane protein 140kDa, antigen CD62)	C00042470
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00042470
6462	SHBG, ABP, SBP, TEBG	sex hormone-binding globulin	C00042470
23411	SIRT1, SIR2L1	sirtuin 1	C00042470
4891	SLC11A2, DCT1, DMT1, NRAMP2	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2	C00042470
66035	SLC2A11, GLUT10, GLUT11	solute carrier family 2 (facilitated glucose transporter), member 11	C00042470
6514	SLC2A2, GLUT2	solute carrier family 2 (facilitated glucose transporter), member 2	C00042470
6515	SLC2A3, GLUT3	solute carrier family 2 (facilitated glucose transporter), member 3	C00042470
6518	SLC2A5, GLUT-5, GLUT5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	C00042470
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00004565
56606	SLC2A9, GLUT9, GLUTX, UAQTL2, URATv1	solute carrier family 2 (facilitated glucose transporter), member 9	C00042470
169026	SLC30A8, ZNT8, ZnT-8	solute carrier family 30 (zinc transporter), member 8	C00042470
6523	SLC5A1, D22S675, NAGT, SGLT1	solute carrier family 5 (sodium/glucose cotransporter), member 1	C00042470
4087	SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2	SMAD family member 2	C00042470
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00042470
4089	SMAD4, DPC4, JIP, MADH4, MYHRS	SMAD family member 4	C00042470
6615	SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1	snail family zinc finger 1	C00042470
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00042470
6648	SOD2, IPOB, MNSOD, MVCD6	superoxide dismutase 2, mitochondrial (EC:1.15.1.1)	C00042470
6667	SP1	Sp1 transcription factor	C00042470
6678	SPARC, ON	secreted protein, acidic, cysteine-rich (osteonectin)	C00042470
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00042470
9882	TBC1D4, AS160	TBC1 domain family, member 4	C00042470
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00042470
7046	TGFBR1, AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, MSSE, SKR4, TGFR-1	transforming growth factor, beta receptor 1 (EC:2.7.11.30)	C00042470
7048	TGFBR2, AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII	transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30)	C00042470
54974	THG1L, ICF45, IHG-1	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) (EC:2.7.7.79)	C00042470
7077	TIMP2, CSC-21K, DDC8	TIMP metallopeptidase inhibitor 2	C00042470
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00042470
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00042470
4982	TNFRSF11B, OCIF, OPG, TR1	tumor necrosis factor receptor superfamily, member 11b	C00042470
10628	TXNIP, EST01027, HHCPA78, THIF, VDUP1	thioredoxin interacting protein	C00042470
7351	UCP2, BMIQ4, SLC25A8, UCPH	uncoupling protein 2 (mitochondrial, proton carrier)	C00042470
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00042470
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00004565
7431	VIM, CTRCT30	vimentin	C00042470
873	CBR1, CBR, SDR21C1, hCBR1	carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184)	C00005413
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00005413
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00005413
3458	IFNG, IFG, IFI	interferon, gamma	C00005413
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00002499
7508	XPC, RAD4, XP3, XPCC	xeroderma pigmentosum, complementation group C	C00002499

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