Onopordum acanthium

• Index
• Plant Species
• Natural Activity
• Metabolite list (15)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Onopordum acanthium
Genus	Onopordum
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Onopordum acanthium
Linked NCBI taxonomy ID	92915
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (10)

Species	Activity
Onopordum acanthium L.	Antipyretic
Onopordum acanthium L.	Antitussive
Onopordum acanthium L.	Aperitif
Onopordum acanthium L.	Cardiotonic
Onopordum acanthium L.	Diuretic
Onopordum acanthium L.	Emmenagogue
Onopordum acanthium L.	Expectorant
Onopordum acanthium L.	Laxative
Onopordum acanthium L.	Stimulant
Onopordum acanthium L.	Stomachic

Metabolite list (15)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004156	Apigenin 7-rutinoside / Apigenin 7-O-rutinoside / Apigenin 7-O-beta-rutinoside	CHEMBL454778				No. 1	No. 15
C00004266	Cinaroside / Luteolin 7-glucoside / Luteolin-7-O-glucoside / Luteolin 7-O-beta-D-glucopyranoside	CHEMBL233929 CHEMBL574683 CHEMBL1159535 CHEMBL1317166	C066408	26 / 31 / 53		No. 2	No. 15
C00005374	Quercetin	CHEMBL82242 CHEMBL479232 CHEMBL1437696	C012526	14 / 2 / 2	2 / 1	No. 2	No. 15
C00005373	Hirsutrin / Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside	CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336		38 / 43 / 34		No. 2	No. 15
C00001029	Chrysoeriol / Luteolin 3'-methyl ether	CHEMBL214321	C007054	20 / 24 / 20	8 / 0	No. 3	No. 15
C00003907	Onopordin / 8-Methoxyluteolin / 5,7,3',4'-Tetrahydroxy-8-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-methoxy-4H-1-benzopyran-4-one	CHEMBL476730				No. 3	No. 15
C00000960	Eriodictyol	CHEMBL8996 CHEMBL307893 CHEMBL1975989	C007619	32 / 29 / 55	5 / 0	No. 25	No. 14
C00007190	(+)-Pinoresinol	CHEMBL267963 CHEMBL487611 CHEMBL460862	C103298	7 / 5 / 6		No. 38	No. 21
C00003341	Onopordopicrin	CHEMBL522604	C075494			No. 60	No. 38
C00003817	Apigenin / 5,7,4'-Trihydroxyflavone	CHEMBL28	D047310	164 / 119 / 105	68 / 8	No. 71	No. 15
C00000609	(-)-Arctigenin	CHEMBL369142 CHEMBL435734 CHEMBL1966556	C071942	13 / 7 / 6		No. 223	No. 21
C00002724	Heriguard / Chlorogenic acid / 3-O-Caffeoylquinic acid	CHEMBL284616 CHEMBL230481 CHEMBL249450 CHEMBL1332980 CHEMBL1394423 CHEMBL1419611 CHEMBL1473644 CHEMBL1552319	D002726	30 / 19 / 22	37 / 9	No. 314	No. 6
C00000615	Caffeic acid	CHEMBL145 CHEMBL1320034		68 / 64 / 63		No. 904	No. 6
C00001205	Succinic acid	CHEMBL576	D019802	6 / 13 / 17	1 / 3	No. 5377
C00007298	Choline	CHEMBL920	D002794	11 / 5 / 5	51 / 20	No. 5945

Human Protein / Gene in interactions

234 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000615 C00000960 C00002724 C00003817 C00004266 C00005373 C00005374	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000615 C00000960 C00002724 C00003817 C00004266 C00005373 C00005374	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000609 C00000615 C00000960 C00001029 C00002724 C00003817 C00007298	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000615 C00000960 C00001029 C00002724 C00003817 C00004266 C00005374	0 / 0
O75496	Geminin	Unclassified protein	C00000960 C00001029 C00002724 C00003817 C00004266 C00005373	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000609 C00000615 C00000960 C00002724 C00003817 C00007298	0 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00000615 C00000960 C00003817 C00004266 C00005373 C00005374	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000615 C00000960 C00002724 C00003817 C00005373 C00005374	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000615 C00000960 C00001029 C00003817 C00004266 C00005373	4 / 3
P39748	Flap endonuclease 1	Enzyme	C00000960 C00001029 C00003817 C00004266 C00005373 C00005374	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000609 C00000960 C00003817 C00004266 C00005373 C00005374	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000609 C00000615 C00000960 C00003817 C00005373	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000609 C00000615 C00002724 C00003817 C00007298	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00000615 C00000960 C00002724 C00004266 C00005374	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000960 C00003817 C00004266 C00005373 C00005374	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000615 C00000960 C00002724 C00003817 C00004266	3 / 3
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000609 C00000615 C00002724 C00003817 C00007298	0 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000615 C00002724 C00003817 C00005373 C00007190	0 / 3
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000609 C00000615 C00002724 C00003817 C00007298	1 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000615 C00001205 C00003817 C00005373	11 / 10
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000615 C00003817 C00005373 C00005374	1 / 1
P15121	Aldose reductase	Enzyme	C00000615 C00002724 C00005373 C00005374	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001029 C00003817 C00004266 C00007190	0 / 0
O00255	Menin	Unclassified protein	C00000615 C00001029 C00003817 C00004266	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000615 C00001029 C00003817 C00004266	1 / 2
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000615 C00002724 C00003817 C00004266	1 / 1
P06746	DNA polymerase beta	Enzyme	C00000615 C00000960 C00001029 C00005373	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000615 C00002724 C00005373 C00007298	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001029 C00003817 C00007190	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001029 C00003817 C00007190	5 / 3
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000960 C00001029 C00003817	4 / 4
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000615 C00000960 C00005373	1 / 1
P14679	Tyrosinase	Oxidoreductase	C00000615 C00004266 C00005373	4 / 2
Q99700	Ataxin-2	Unclassified protein	C00000609 C00003817 C00004266	1 / 1
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000960 C00003817 C00004266	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000960 C00003817 C00004266	7 / 37
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00001029 C00003817 C00004266	4 / 2
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00001029 C00003817 C00007190	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000960 C00001029 C00003817	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001029 C00003817 C00004266	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000615 C00000960 C00003817	2 / 2
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000960 C00003817 C00005373	1 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000609 C00001029 C00003817	2 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000615 C00002724 C00003817	3 / 2
P22303	Acetylcholinesterase	Hydrolase	C00000960 C00003817 C00007298	1 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00003817 C00005373	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00003817 C00005373	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000615 C00003817	3 / 1
P03372	Estrogen receptor	NR3A1	C00000615 C00003817	1 / 1
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000615 C00003817	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000615 C00003817	5 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00000609 C00003817	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000960 C00003817	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00001029 C00003817	1 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00003817 C00005373	2 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00003817 C00005373	4 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000615 C00005373	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00003817 C00005373	0 / 1
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000960 C00005373	0 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003817 C00004266	1 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00003817 C00005373	1 / 4
P06280	Alpha-galactosidase A	Enzyme	C00000615 C00005373	1 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002724 C00003817	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005373 C00005374	0 / 0
Q9GZT9	Egl nine homolog 1	Enzyme	C00000615 C00001205	1 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001029 C00005373	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000615 C00003817	1 / 8
P04062	Glucosylceramidase	Enzyme	C00003817 C00005373	6 / 4
P06239	Tyrosine-protein kinase Lck	Src	C00002724 C00003817	0 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000615 C00003817	0 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00003817 C00005373	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002724 C00003817	0 / 1
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000615 C00002724	3 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000960 C00004266	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00004266 C00005374	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000960 C00005373	3 / 1
P24298	Alanine aminotransferase 1	Enzyme	C00000615 C00004266	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000960 C00005373	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00001029 C00003817	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000615 C00002724	2 / 2
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000615 C00003817	0 / 0
P10145	Interleukin-8	Secreted protein	C00002724 C00003817	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00000615 C00002724	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00003817 C00005373	0 / 0
Q02750	Dual specificity mitogen-activated protein kinase kinase 1	Ste7	C00000609 C00003817	1 / 1
P14618	Pyruvate kinase PKM	Enzyme	C00000960 C00003817	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000615 C00007190	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00000960 C00004266	2 / 1
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00001205	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002724	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00000609	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00003817	0 / 0
P09769	Tyrosine-protein kinase Fgr	Src	C00003817	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00003817	0 / 1
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00000615	0 / 0
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000615	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000615	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003817	0 / 0
Q15418	Ribosomal protein S6 kinase alpha-1	Rskb	C00003817	0 / 0
O15264	Mitogen-activated protein kinase 13	p38	C00003817	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00002724	1 / 2
P09874	Poly [ADP-ribose] polymerase 1	Enzyme	C00003817	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000609	0 / 0
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00003817	1 / 1
P03956	Interstitial collagenase	M10A	C00000615	0 / 1
O43570	Carbonic anhydrase 12	Lyase	C00000615	1 / 2
P68871	Hemoglobin subunit beta	Secreted protein	C00003817	4 / 4
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000615	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000960	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00003817	0 / 0
O75582	Ribosomal protein S6 kinase alpha-5	CAMK serine/threonine protein kinase MSKB subfamily	C00003817	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003817	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000615	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00003817	2 / 2
P11473	Vitamin D3 receptor	NR1I1	C00003817	2 / 3
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003817	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00003817	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00002724	0 / 0
P06276	Cholinesterase	Hydrolase	C00003817	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00003817	0 / 0
P49137	MAP kinase-activated protein kinase 2	CAMK serine/threonine protein kinase MAPKAPK	C00003817	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003817	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00000615	0 / 0
P23443	Ribosomal protein S6 kinase beta-1	p70	C00003817	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00003817	0 / 0
P56817	Beta-secretase 1	A1A	C00003817	0 / 0
P08183	Multidrug resistance protein 1	drug	C00003817	1 / 0
Q7Z4W1	L-xylulose reductase	Enzyme	C00001205	0 / 1
Q16790	Carbonic anhydrase 9	Lyase	C00000615	0 / 1
P08253	72 kDa type IV collagenase	M10A	C00000615	1 / 3
Q00987	E3 ubiquitin-protein ligase Mdm2	Other nuclear protein	C00001205	1 / 5
Q9Y4K4	Mitogen-activated protein kinase kinase kinase kinase 5	STE serine/threonine protein kinase KHS subfamily	C00003817	0 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00000615	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00003817	0 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00003817	1 / 0
P51692	Signal transducer and activator of transcription 5B	Unclassified protein	C00002724	1 / 1
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000615	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005373	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00003817	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00000615	1 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00003817	0 / 0
P68400	Casein kinase II subunit alpha	Ck2	C00003817	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00003817	0 / 0
Q9H2K2	Tankyrase-2	Enzyme	C00003817	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00003817	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00003817	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003817	0 / 0
O95271	Tankyrase-1	Enzyme	C00003817	0 / 0
Q8IW41	MAP kinase-activated protein kinase 5	CAMK serine/threonine protein kinase MAPKAPK	C00003817	0 / 0
O75116	Rho-associated protein kinase 2	Rock	C00003817	0 / 0
O15245	Solute carrier family 22 member 1	Drug uniporter	C00007298	0 / 0
P07948	Tyrosine-protein kinase Lyn	Src	C00003817	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00003817	0 / 0
O14757	Serine/threonine-protein kinase Chk1	Chk1	C00003817	0 / 0
P31749	RAC-alpha serine/threonine-protein kinase	Akt	C00003817	4 / 1
O00141	Serine/threonine-protein kinase Sgk1	AGC serine/threonine protein kinase SGK subfamily	C00003817	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000615	2 / 2
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00003817	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00003817	0 / 0
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00000615	4 / 2
Q15046	Lysine--tRNA ligase	Enzyme	C00003817	2 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00003817	1 / 0
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000615	1 / 0
P43166	Carbonic anhydrase 7	Lyase	C00000615	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000615	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00003817	5 / 1
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000615	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00003817	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002724	0 / 0
P41240	Tyrosine-protein kinase CSK	Csk	C00003817	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00005373	1 / 0
P10275	Androgen receptor	NR3C4	C00003817	3 / 4
O15530	3-phosphoinositide-dependent protein kinase 1	Pdk1	C00003817	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000615	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00003817	0 / 0
P54646	5'-AMP-activated protein kinase catalytic subunit alpha-2	Ampk	C00003817	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00003817	0 / 0
P43405	Tyrosine-protein kinase SYK	Syk	C00003817	0 / 0
P34949	Mannose-6-phosphate isomerase	Enzyme	C00005373	1 / 1
Q13627	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	CMGC dual-specificity kinase DYRK1	C00003817	1 / 0
P22748	Carbonic anhydrase 4	Lyase	C00000615	1 / 1
P53778	Mitogen-activated protein kinase 12	p38	C00003817	0 / 0
Q12794	Hyaluronidase-1	Enzyme	C00000615	1 / 2
Q15759	Mitogen-activated protein kinase 11	p38	C00003817	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00003817	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00003817	0 / 0
Q16798	NADP-dependent malic enzyme, mitochondrial	Enzyme	C00001205	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00003817	1 / 1
P42224	Signal transducer and activator of transcription 1-alpha/beta	Unclassified protein	C00002724	3 / 3
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003817	2 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00003817	0 / 0
O15244	Solute carrier family 22 member 2	Drug uniporter	C00007298	0 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000615	1 / 0
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00005374	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000615	0 / 0
Q9UN88	Gamma-aminobutyric acid receptor subunit theta	GABA-A theta	C00003817	0 / 0
P28472	Gamma-aminobutyric acid receptor subunit beta-3	GABA-A beta	C00003817	1 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00003817	1 / 1
P48169	Gamma-aminobutyric acid receptor subunit alpha-4	GABA-A alpha	C00003817	0 / 0
O14764	Gamma-aminobutyric acid receptor subunit delta	GABA-A delta	C00003817	1 / 1
P31644	Gamma-aminobutyric acid receptor subunit alpha-5	GABA-A alpha	C00003817	0 / 0
Q99928	Gamma-aminobutyric acid receptor subunit gamma-3	GABA-A gamma	C00003817	0 / 0
P78334	Gamma-aminobutyric acid receptor subunit epsilon	GABA-A epsilon	C00003817	0 / 0
Q8N1C3	Gamma-aminobutyric acid receptor subunit gamma-1	GABA-A gamma	C00003817	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00003817	3 / 0
O00591	Gamma-aminobutyric acid receptor subunit pi	GABA-A pi	C00003817	0 / 0
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00003817	0 / 0
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00003817	4 / 2
P18505	Gamma-aminobutyric acid receptor subunit beta-1	GABA-A beta	C00003817	0 / 0
Q16445	Gamma-aminobutyric acid receptor subunit alpha-6	GABA-A alpha	C00003817	0 / 0
P47869	Gamma-aminobutyric acid receptor subunit alpha-2	GABA-A alpha	C00003817	1 / 0
P45983	Mitogen-activated protein kinase 8	Jnk	C00003817	0 / 0
P53779	Mitogen-activated protein kinase 10	Jnk	C00003817	0 / 1
P45984	Mitogen-activated protein kinase 9	Jnk	C00003817	0 / 0
Q9H015	Solute carrier family 22 member 4	Unclassified protein	C00007298	1 / 1
O76082	Solute carrier family 22 member 5	Unclassified protein	C00007298	1 / 2
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00003817	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00003817	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00003817	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00003817	0 / 0
P22694	cAMP-dependent protein kinase catalytic subunit beta	Pka	C00003817	0 / 0
P17612	cAMP-dependent protein kinase catalytic subunit alpha	Pka	C00003817	0 / 0
P22612	cAMP-dependent protein kinase catalytic subunit gamma	Pka	C00003817	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00000615	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00000615	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00003817	0 / 0
Q9HCP0	Casein kinase I isoform gamma-1	Ck1	C00003817	0 / 0
P48730	Casein kinase I isoform delta	Ck1	C00003817	1 / 0
P49674	Casein kinase I isoform epsilon	Ck1	C00003817	0 / 0
P78368	Casein kinase I isoform gamma-2	Ck1	C00003817	0 / 0
P48729	Casein kinase I isoform alpha	Ck1	C00003817	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00003817	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00007190	0 / 0
P34903	Gamma-aminobutyric acid receptor subunit alpha-3	GABA-A alpha	C00003817	0 / 0

159 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000960 C00001029 C00003817
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001029 C00003817 C00005374
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001029 C00003817 C00005374
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00003817 C00007298
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00001029 C00003817
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001029 C00003817
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002724 C00003817
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002724 C00003817
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002724 C00003817
5241	PGR, NR3C3, PR	progesterone receptor	C00002724 C00003817
1584	CYP11B1, CPN1, CYP11B, FHI, P450C11	cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4)	C00003817
29110	TBK1, NAK, T2K	TANK-binding kinase 1 (EC:2.7.11.1)	C00000960
47	ACLY, ACL, ATPCL, CLATP	ATP citrate lyase (EC:2.3.3.8)	C00002724
358	AQP1, AQP-CHIP, CHIP28, CO	aquaporin 1	C00002724
360	AQP3, AQP-3, GIL	aquaporin 3 (Gill blood group)	C00002724
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00002724
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00002724
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00002724
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002724
4512	COX1, COI, MTCO1, MT-CO1	cytochrome c oxidase subunit I	C00002724
114757	CYGB, HGB, STAP	cytoglobin	C00002724
1830	DSG3, CDHF6, PVA	desmoglein 3	C00002724
1950	EGF, HOMG4, URG	epidermal growth factor	C00002724
2200	FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2	fibrillin 1	C00002724
2201	FBN2, CCA, DA9	fibrillin 2	C00002724
2246	FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1	fibroblast growth factor 1 (acidic)	C00002724
2896	GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN	granulin	C00002724
3036	HAS1, HAS	hyaluronan synthase 1 (EC:2.4.1.212)	C00002724
3315	HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27	heat shock 27kDa protein 1	C00002724
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00002724
3852	KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A	keratin 5	C00002724
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00002724
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002724
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000960
8985	PLOD3, LH3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4)	C00002724
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00002724
5886	RAD23A, HHR23A, HR23A	RAD23 homolog A (S. cerevisiae)	C00002724
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00002724
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00002724
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00002724
6716	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22)	C00002724
7178	TPT1, HRF, TCTP, p02, p23	tumor protein, translationally-controlled 1	C00002724
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00002724
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00002724
7306	TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN	tyrosinase-related protein 1 (EC:1.14.18.-)	C00002724
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000960
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002724
4835	NQO2, DHQV, DIA6, NMOR2, QR2	NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2)	C00001029
4544	MTNR1B, FGQTL2, MEL-1B-R, MT2	melatonin receptor 1B	C00001029
43	ACHE, ACEE, ARACHE, N-ACHE, YT	acetylcholinesterase (EC:3.1.1.7)	C00007298
8854	ALDH1A2, RALDH(II), RALDH2, RALDH2-T	aldehyde dehydrogenase 1 family, member A2 (EC:1.2.1.36)	C00007298
64333	ARHGAP9, 10C, RGL1	Rho GTPase activating protein 9	C00007298
590	BCHE, CHE1, CHE2, E1	butyrylcholinesterase (EC:3.1.1.8)	C00007298
701	BUB1B, BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1	BUB1 mitotic checkpoint serine/threonine kinase B (EC:2.7.11.1)	C00007298
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00007298
9332	CD163, M130, MM130	CD163 molecule	C00007298
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00007298
55143	CDCA8, BOR, BOREALIN, DasraB, MESRGP	cell division cycle associated 8	C00007298
55349	CHDH	choline dehydrogenase (EC:1.1.99.1)	C00007298
1111	CHEK1, CHK1	checkpoint kinase 1 (EC:2.7.11.1)	C00007298
1137	CHRNA4, BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4	cholinergic receptor, nicotinic, alpha 4 (neuronal)	C00007298
1139	CHRNA7, CHRNA7-2, NACHRA7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	C00007298
1141	CHRNB2, EFNL3, nAChRB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	C00007298
81035	COLEC12, CLP1, NSR2, SCARA4, SRCL	collectin sub-family member 12	C00007298
1440	CSF3, C17orf33, CSF3OS, GCSF, G-CSF	colony stimulating factor 3 (granulocyte)	C00007298
1471	CST3, ARMD11	cystatin C	C00007298
1514	CTSL, CATL, CTSL1, MEP	cathepsin L (EC:3.4.22.15)	C00007298
1524	CX3CR1, CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28	chemokine (C-X3-C motif) receptor 1	C00007298
1794	DOCK2	dedicator of cytokinesis 2	C00007298
3169	FOXA1, HNF3A, TCF3A	forkhead box A1	C00007298
2632	GBE1, APBD, GBE, GSD4	glucan (1,4-alpha-), branching enzyme 1 (EC:2.4.1.18)	C00007298
3003	GZMK, TRYP2	granzyme K (granzyme 3; tryptase II) (EC:3.4.21.-)	C00007298
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00007298
396742			C00007298
3560	IL2RB, CD122, IL15RB, P70-75	interleukin 2 receptor, beta	C00007298
10112	KIF20A, MKLP2, RAB6KIFL	kinesin family member 20A	C00007298
9493	KIF23, CHO1, KNSL5, MKLP-1, MKLP1	kinesin family member 23	C00007298
51348	KLRF1, CLEC5C, NKp80	killer cell lectin-like receptor subfamily F, member 1	C00007298
114569	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)	C00007298
55016	MARCH1, MARCH-I, RNF171	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase	C00007298
4256	MGP, MGLAP, NTI	matrix Gla protein	C00007298
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00007298
4522	MTHFD1, MTHFC, MTHFD	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (EC:1.5.1.5 6.3.4.3 3.5.4.9)	C00007298
9172	MYOM2, TTNAP	myomesin 2	C00007298
4543	MTNR1A, MEL-1A-R, MT1	melatonin receptor 1A	C00001029
11333	PDAP1, HASPP28, PAP, PAP1	PDGFA associated protein 1	C00007298
10400	PEMT, PEAMT, PEMPT, PEMT2, PNMT	phosphatidylethanolamine N-methyltransferase (EC:2.1.1.17 2.1.1.71)	C00007298
5329	PLAUR, CD87, U-PAR, UPAR, URKR	plasminogen activator, urokinase receptor	C00007298
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00007298
23532	PRAME, CT130, MAPE, OIP-4, OIP4	preferentially expressed antigen in melanoma	C00007298
5790	PTPRCAP, CD45-AP, LPAP	protein tyrosine phosphatase, receptor type, C-associated protein	C00007298
10287	RGS19, GAIP, RGSGAIP	regulator of G-protein signaling 19	C00007298
57140	RNPEPL1	arginyl aminopeptidase (aminopeptidase B)-like 1	C00007298
6422	SFRP1, FRP, FRP-1, FRP1, FrzA, SARP2	secreted frizzled-related protein 1	C00007298
6584	SLC22A5, CDSP, OCTN2, OCTN2VT	solute carrier family 22 (organic cation/carnitine transporter), member 5	C00007298
9056	SLC7A7, LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7	C00007298
6594	SMARCA1, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SNF2LT, SWI, SWI2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	C00007298
7015	TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT	telomerase reverse transcriptase (EC:2.7.7.49)	C00007298
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00007298
83549	UCK1, URK1	uridine-cytidine kinase 1 (EC:2.7.1.48)	C00007298
64849	SLC13A3, NADC3, SDCT2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	C00001205
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003817
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00003817
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00003817
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003817
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003817
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003817
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00003817
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00003817
847	CAT	catalase (EC:1.11.1.6)	C00003817
891	CCNB1, CCNB	cyclin B1	C00003817
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00003817
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00003817
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003817
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00003817
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00003817
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00003817
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00003817
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000960
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00003817
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003817
1589	CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B	cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10)	C00003817
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00003817
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00003817
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00003817
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00003817
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00003817
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00003817
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00003817
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003817
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00003817
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00003817
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00003817
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00003817
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003817
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003817
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003817
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00003817
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00003817
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00003817
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00003817
8000	PSCA, PRO232	prostate stem cell antigen	C00003817
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00003817
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00003817
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00003817
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00003817
6783	SULT1E1, EST, EST-1, ST1E1, STE	sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4)	C00003817
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00003817
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00003817
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00003817
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00003817
7161	TP73, P73	tumor protein p73	C00003817
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00003817
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00003817
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00003817
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00003817
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00003817
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00003817
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00003817

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