Species

KNApSAcK Entry

Organism name Pedilanthus tithymaloides
Genus Pedilanthus
Family Euphorbiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Euphorbia tithymaloides
Linked NCBI taxonomy ID 212310
Linked level species

Family

Family in NCBI taxonomy Euphorbiaceae
ID 3977

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (14)

Species Activity
Pedilanthus tithymaloides (L.) Poit. Abortifacient
Pedilanthus tithymaloides (L.) Poit. Analgesic
Pedilanthus tithymaloides (L.) Poit. Antibiotic
Pedilanthus tithymaloides (L.) Poit. Antihemorrhagic
Pedilanthus tithymaloides (L.) Poit. Antiinflammatory
Pedilanthus tithymaloides (L.) Poit. Antiseptic
Pedilanthus tithymaloides (L.) Poit. Antitumor
Pedilanthus tithymaloides (L.) Poit. Antiviral
Pedilanthus tithymaloides (L.) Poit. Depurative
Pedilanthus tithymaloides (L.) Poit. Emetic
Pedilanthus tithymaloides (L.) Poit. Emmenagogue
Pedilanthus tithymaloides (L.) Poit. Pectoral
Pedilanthus tithymaloides (L.) Poit. Purgative
Pedilanthus tithymaloides (L.) Poit. Sialagogue

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005373 External link 512 Hirsutrin
/ Isoquercetin
/ Isoquercetrin
/ (-)-Isoquercetrin
/ Quercetin 3-glucoside
/ Quercetin 3-O-beta-D-glucoside
/ Quercetin-3-O-beta-D-glucopyranoside
/ Quercetin 3-O-beta-D-glucopyranoside
/ (-)-Quercetin-3-O-beta-D-glucopyranoside
CHEMBL33027
CHEMBL309323
CHEMBL250450
CHEMBL251254
CHEMBL457304
CHEMBL1098724
CHEMBL2337335
CHEMBL2337336
38 / 43 / 34 No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00003738 External link 512 beta-Amyrin
/ beta-Amirin
/ beta-Amyrine
/ beta-Amyrenol
C036380
0 / 4 No. 23 No. 51
C00003749 External link 512 Lupeol
/ Lupenol
/ (+)-Lupenol
CHEMBL289191
CHEMBL459702
C010480
3 / 0 / 0 2 / 6 No. 23 No. 51
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00040493 External link 512 Tirucalla-7,24-dien-3beta-ol
CHEMBL1835433
No. 119 No. 51
C00003650 External link 512 Cycloartenol
CHEMBL119938
CHEMBL225815
CHEMBL226036
CHEMBL393145
CHEMBL2007217
C100089
0 / 1 No. 129 No. 11
C00002499 External link 512 Scopoletin
CHEMBL71851
D012603
48 / 37 / 34 9 / 0 No. 864 No. 25

Human Protein / Gene in interactions

91 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002499 C00005373 C00005374 0 / 0
P15121 Aldose reductase Enzyme C00002499 C00005373 C00005374 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00002499 C00005373 C00005374 1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002499 C00005373 0 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00005373 C00005374 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005373 C00005374 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005373 C00005374 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002499 C00003672 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002499 C00003672 1 / 1
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00002499 C00003672 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002499 C00003672 0 / 0
P06280 Alpha-galactosidase A Enzyme C00002499 C00005373 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002499 C00003672 1 / 0
P06746 DNA polymerase beta Enzyme C00003672 C00005373 0 / 0
P04062 Glucosylceramidase Enzyme C00002499 C00005373 6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase C00002499 C00005373 1 / 1
P14679 Tyrosinase Oxidoreductase C00003672 C00005373 4 / 2
Q9Y253 DNA polymerase eta Enzyme C00005373 C00005374 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002499 C00005373 0 / 0
O75496 Geminin Unclassified protein C00002499 C00005373 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005373 C00005374 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002499 C00005374 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005373 C00005374 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003672 C00003749 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002499 C00003672 0 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005373 C00005374 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00002499 1 / 2
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00005373 0 / 0
P08183 Multidrug resistance protein 1 drug C00003672 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00003672 3 / 2
P55789 FAD-linked sulfhydryl oxidase ALR Enzyme C00002499 1 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005373 1 / 0
P11387 DNA topoisomerase 1 Isomerase C00003749 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00003749 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00005373 0 / 0
P02545 Prelamin-A/C Unclassified protein C00005373 11 / 10
O43570 Carbonic anhydrase 12 Lyase C00002499 1 / 2
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00005373 1 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00002499 0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase C00002499 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002499 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00002499 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002499 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00002499 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00005373 0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00002499 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002499 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002499 7 / 3
Q04206 Transcription factor p65 Transcription Factor C00002499 0 / 0
P29466 Caspase-1 C14 C00002499 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00005373 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00005373 3 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
P00734 Prothrombin S1A C00003672 4 / 2
P43166 Carbonic anhydrase 7 Lyase C00002499 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002499 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00005373 0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00005373 0 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002499 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002499 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00005373 2 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002499 2 / 2
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00002499 0 / 0
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002499 0 / 0
P03372 Estrogen receptor NR3A1 C00003672 1 / 1
Q99700 Ataxin-2 Unclassified protein C00002499 1 / 1
P35372 Mu-type opioid receptor Opioid receptor C00005373 0 / 0
Q00796 Sorbitol dehydrogenase Enzyme C00002499 0 / 0
P55210 Caspase-7 C14 C00002499 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00002499 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00005373 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00005373 4 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00005374 0 / 0
Q9NPH5 NADPH oxidase 4 Enzyme C00005373 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00002499 5 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00005373 4 / 3
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00005373 1 / 0
P34949 Mannose-6-phosphate isomerase Enzyme C00005373 1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
O75795 UDP-glucuronosyltransferase 2B17 Enzyme C00002499 1 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002499 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00002499 3 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003672 1 / 1
O00255 Menin Unclassified protein C00002499 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002499 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00005373 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00005373 1 / 4
P22303 Acetylcholinesterase Hydrolase C00002499 1 / 0

13 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00003749
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00003749
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005374
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00002499
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002499
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002499
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00002499
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002499
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002499
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00002499
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00002499
7508 XPC, RAD4, XP3, XPCC xeroderma pigmentosum, complementation group C C00002499

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (84)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#218030 Apparent mineralocorticoid excess; ame P80365
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#615363 Estrogen resistance; estrr P03372
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#143500 Gilbert syndrome P22309
P22310
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#601626 Leukemia, acute myeloid; aml P36888
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613076 Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay P55789
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#614674 Periodic fever, menstrual cycle-dependent P08908
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P00734
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (63)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00213 Hypophosphatasia P05186 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00192 Xanthinuria P47989 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

10 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D012878 Skin Neoplasms C00003749
C00003650
D010146 Pain C00005374
C00003738
D014947 Wounds and Injuries C00003749
D009374 Neoplasms, Experimental C00003749
D006528 Carcinoma, Hepatocellular C00003749
D006937 Hypercholesterolemia C00003749
D009202 Cardiomyopathies C00003749
D005157 Facial Pain C00003738
D006930 Hyperalgesia C00003738
D007249 Inflammation C00003738