| Organism name | Pedilanthus tithymaloides | 
|---|---|
| Genus | Pedilanthus | 
| Family | Euphorbiaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Euphorbia tithymaloides | 
|---|---|
| Linked NCBI taxonomy ID | 212310 | 
| Linked level | species | 
| Family in NCBI taxonomy | Euphorbiaceae | 
|---|---|
| ID | 3977 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| Species | Activity | 
|---|---|
| Pedilanthus tithymaloides (L.) Poit. | Abortifacient | 
| Pedilanthus tithymaloides (L.) Poit. | Analgesic | 
| Pedilanthus tithymaloides (L.) Poit. | Antibiotic | 
| Pedilanthus tithymaloides (L.) Poit. | Antihemorrhagic | 
| Pedilanthus tithymaloides (L.) Poit. | Antiinflammatory | 
| Pedilanthus tithymaloides (L.) Poit. | Antiseptic | 
| Pedilanthus tithymaloides (L.) Poit. | Antitumor | 
| Pedilanthus tithymaloides (L.) Poit. | Antiviral | 
| Pedilanthus tithymaloides (L.) Poit. | Depurative | 
| Pedilanthus tithymaloides (L.) Poit. | Emetic | 
| Pedilanthus tithymaloides (L.) Poit. | Emmenagogue | 
| Pedilanthus tithymaloides (L.) Poit. | Pectoral | 
| Pedilanthus tithymaloides (L.) Poit. | Purgative | 
| Pedilanthus tithymaloides (L.) Poit. | Sialagogue | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00005373   | Hirsutrin / Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside | CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 | 38 / 43 / 34 | No. 2 | No. 15 |   | ||
| C00005374   | Quercetin | CHEMBL82242 CHEMBL479232 CHEMBL1437696 | C012526 | 14 / 2 / 2 | 2 / 1 | No. 2 | No. 15 |   | 
| C00003738   | beta-Amyrin / beta-Amirin / beta-Amyrine / beta-Amyrenol | C036380 | 0 / 4 | No. 23 | No. 51 |   | ||
| C00003749   | Lupeol / Lupenol / (+)-Lupenol | CHEMBL289191 CHEMBL459702 | C010480 | 3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |   | 
| C00003672   | Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol | CHEMBL221542 CHEMBL1398443 CHEMBL1875388 | 17 / 19 / 12 | No. 53 | No. 11 |   | ||
| C00040493   | Tirucalla-7,24-dien-3beta-ol | CHEMBL1835433 | No. 119 | No. 51 |   | |||
| C00003650   | Cycloartenol | CHEMBL119938 CHEMBL225815 CHEMBL226036 CHEMBL393145 CHEMBL2007217 | C100089 | 0 / 1 | No. 129 | No. 11 |   | |
| C00002499   | Scopoletin | CHEMBL71851 | D012603 | 48 / 37 / 34 | 9 / 0 | No. 864 | No. 25 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002499 C00005373 C00005374 | 0 / 0 | 
| P15121 | Aldose reductase | Enzyme | C00002499 C00005373 C00005374 | 0 / 0 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002499 C00005373 C00005374 | 1 / 1 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002499 C00005373 | 0 / 3 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005373 C00005374 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005373 C00005374 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00005373 C00005374 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002499 C00003672 | 0 / 1 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002499 C00003672 | 1 / 1 | 
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00002499 C00003672 | 0 / 0 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002499 C00003672 | 0 / 0 | 
| P06280 | Alpha-galactosidase A | Enzyme | C00002499 C00005373 | 1 / 1 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002499 C00003672 | 1 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00003672 C00005373 | 0 / 0 | 
| P04062 | Glucosylceramidase | Enzyme | C00002499 C00005373 | 6 / 4 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002499 C00005373 | 1 / 1 | 
| P14679 | Tyrosinase | Oxidoreductase | C00003672 C00005373 | 4 / 2 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00005373 C00005374 | 1 / 1 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002499 C00005373 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00002499 C00005373 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00005373 C00005374 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002499 C00005374 | 0 / 0 | 
| P07237 | Protein disulfide-isomerase | Enzyme | C00005373 C00005374 | 0 / 0 | 
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00003749 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002499 C00003672 | 0 / 1 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005373 C00005374 | 0 / 0 | 
| P00918 | Carbonic anhydrase 2 | Lyase | C00002499 | 1 / 2 | 
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00005373 | 0 / 0 | 
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 | 
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002499 | 1 / 0 | 
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00005373 | 1 / 0 | 
| P11387 | DNA topoisomerase 1 | Isomerase | C00003749 | 0 / 0 | 
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003749 | 0 / 0 | 
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00005373 | 0 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00005373 | 11 / 10 | 
| O43570 | Carbonic anhydrase 12 | Lyase | C00002499 | 1 / 2 | 
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00005373 | 1 / 1 | 
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002499 | 0 / 0 | 
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002499 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002499 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002499 | 0 / 0 | 
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00002499 | 0 / 0 | 
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002499 | 0 / 0 | 
| P41143 | Delta-type opioid receptor | Opioid receptor | C00005373 | 0 / 0 | 
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002499 | 0 / 0 | 
| P00915 | Carbonic anhydrase 1 | Lyase | C00002499 | 0 / 0 | 
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002499 | 7 / 3 | 
| Q04206 | Transcription factor p65 | Transcription Factor | C00002499 | 0 / 0 | 
| P29466 | Caspase-1 | C14 | C00002499 | 0 / 0 | 
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00005373 | 0 / 0 | 
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00005373 | 3 / 1 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005374 | 0 / 0 | 
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 | 
| P43166 | Carbonic anhydrase 7 | Lyase | C00002499 | 0 / 0 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002499 | 0 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00005373 | 0 / 0 | 
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00005373 | 0 / 1 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 | 
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002499 | 0 / 1 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002499 | 3 / 3 | 
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00005373 | 2 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002499 | 2 / 2 | 
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00002499 | 0 / 0 | 
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002499 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00003672 | 1 / 1 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00002499 | 1 / 1 | 
| P35372 | Mu-type opioid receptor | Opioid receptor | C00005373 | 0 / 0 | 
| Q00796 | Sorbitol dehydrogenase | Enzyme | C00002499 | 0 / 0 | 
| P55210 | Caspase-7 | C14 | C00002499 | 0 / 0 | 
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002499 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00005373 | 0 / 0 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00005373 | 4 / 1 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00005374 | 0 / 0 | 
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00005373 | 0 / 0 | 
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002499 | 5 / 1 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00005373 | 4 / 3 | 
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005373 | 1 / 0 | 
| P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005373 | 1 / 1 | 
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 | 
| O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00002499 | 1 / 0 | 
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00005374 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002499 | 0 / 0 | 
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00002499 | 3 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 | 
| O00255 | Menin | Unclassified protein | C00002499 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002499 | 1 / 2 | 
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00005373 | 0 / 1 | 
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00005373 | 1 / 4 | 
| P22303 | Acetylcholinesterase | Hydrolase | C00002499 | 1 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa | C00003749 | 
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | C00003749 | 
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00005374 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00005374 | 
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | C00002499 | 
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) | C00002499 | 
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) | C00002499 | 
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) | C00002499 | 
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) | C00002499 | 
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) | C00002499 | 
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) | C00002499 | 
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) | C00002499 | 
| 7508 | XPC, RAD4, XP3, XPCC | xeroderma pigmentosum, complementation group C | C00002499 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #103470 | Albinism, ocular, with sensorineural deafness | P14679 | 
| #203100 | Albinism, oculocutaneous, type ia; oca1a | P14679 | 
| #606952 | Albinism, oculocutaneous, type ib; oca1b | P14679 | 
| #218030 | Apparent mineralocorticoid excess; ame | P80365 | 
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 | P22309 | 
| #614490 | Blood group, junior system; jr | Q9UNQ0 | 
| #612560 | Bone mineral density quantitative trait locus 12; bmnd12 | O75795 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #602579 | Congenital disorder of glycosylation, type ib; cdg1b | P34949 | 
| #218800 | Crigler-najjar syndrome, type i | P22309 P22310 | 
| #606785 | Crigler-najjar syndrome, type ii | P22309 P22310 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #301500 | Fabry disease | P06280 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #608013 | Gaucher disease, perinatal lethal | P04062 | 
| #230800 | Gaucher disease, type i | P04062 | 
| #230900 | Gaucher disease, type ii | P04062 | 
| #231000 | Gaucher disease, type iii | P04062 | 
| #231005 | Gaucher disease, type iiic | P04062 | 
| #143500 | Gilbert syndrome | P22309 P22310 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn | P22309 | 
| #143860 | Hyperchlorhidrosis, isolated | O43570 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #146300 | Hypophosphatasia, adult | P05186 | 
| #241510 | Hypophosphatasia, childhood | P05186 | 
| #241500 | Hypophosphatasia, infantile | P05186 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #601626 | Leukemia, acute myeloid; aml | P36888 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay | P55789 | 
| #160900 | Myotonic dystrophy 1; dm1 | Q9NR56 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 | P00918 | 
| #168600 | Parkinson disease, late-onset; pd | P04062 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #614674 | Periodic fever, menstrual cycle-dependent | P08908 | 
| #172700 | Pick disease of brain | P10636 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #601399 | Platelet disorder, familial, with associated myeloid malignancy | Q01196 | 
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 | P00734 | 
| #613679 | Prothrombin deficiency, congenital | P00734 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | P14679 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #601367 | Stroke, ischemic | P00734 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #188050 | Thrombophilia due to thrombin defect; thph1 | P00734 | 
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 | Q9UNQ0 | 
| #278300 | Xanthinuria, type i | P47989 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| #112100 | Yt blood group antigen | P22303 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H01302 | Hyperchlorhidrosis isolated (HCHLH) | O43570
                            (related) | 
| H00021 | Renal cell carcinoma | O43570
                            (marker) Q16790 (marker) | 
| H00223 | Inherited thrombophilia | P00734
                            (related) | 
| H01254 | Congenital prothrombin deficiency | P00734
                            (related) | 
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) | P00918
                            (related) | 
| H00436 | Osteopetrosis | P00918
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) | 
| H00066 | Lewy body dementia (LBD) | P04062
                            (related) | 
| H00126 | Gaucher disease | P04062
                            (related) | 
| H00426 | Defects in the degradation of ganglioside | P04062
                            (related) | 
| H00810 | Progressive myoclonic epilepsy (PME) | P04062
                            (related) | 
| H00213 | Hypophosphatasia | P05186
                            (related) | 
| H00125 | Fabry disease | P06280
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00023 | Testicular cancer | P10696
                            (marker) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00168 | Oculocutaneous albinism (OCA) | P14679
                            (related) | 
| H00038 | Malignant melanoma | P14679
                            (marker) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00208 | Hyperbilirubinemia | P22309
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00118 | Congenital disorders of glycosylation (CDG) type I | P34949
                            (related) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00003 | Acute myeloid leukemia (AML) | P36888
                            (related) Q01196 (related) Q01196 (marker) Q13951 (marker) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00259 | Apparent mineralocorticoid excess syndrome | P80365
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q01196
                            (related) Q01196 (marker) Q03164 (related) Q03164 (marker) | 
| H00004 | Chronic myeloid leukemia (CML) | Q01196
                            (related) | 
| H00978 | Thrombocytopenia (THC) | Q01196
                            (related) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) Q9NUW8 (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D012878 | Skin Neoplasms | C00003749 C00003650 | 
| D010146 | Pain | C00005374 C00003738 | 
| D014947 | Wounds and Injuries | C00003749 | 
| D009374 | Neoplasms, Experimental | C00003749 | 
| D006528 | Carcinoma, Hepatocellular | C00003749 | 
| D006937 | Hypercholesterolemia | C00003749 | 
| D009202 | Cardiomyopathies | C00003749 | 
| D005157 | Facial Pain | C00003738 | 
| D006930 | Hyperalgesia | C00003738 | 
| D007249 | Inflammation | C00003738 |