Eucalyptus globulus
Species
KNApSAcK Entry
| Organism name | Eucalyptus globulus |
|---|---|
| Genus | Eucalyptus |
| Family | Myrtaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Eucalyptus globulus |
|---|---|
| Linked NCBI taxonomy ID | 34317 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Myrtaceae |
|---|---|
| ID | 3931 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (33)
| Species | Activity |
|---|---|
| Eucalyptus globulus Labill. | Analgesic |
| Eucalyptus globulus Labill. | Anesthetic |
| Eucalyptus globulus Labill. | Anthelminthic |
| Eucalyptus globulus Labill. | Antibacterial |
| Eucalyptus globulus Labill. | Antidiabetic |
| Eucalyptus globulus Labill. | Antiinflammatory |
| Eucalyptus globulus Labill. | Antiproliferative |
| Eucalyptus globulus Labill. | Antipyretic |
| Eucalyptus globulus Labill. | Antiseptic |
| Eucalyptus globulus Labill. | Antispasmodic |
| Eucalyptus globulus Labill. | Antitumor |
| Eucalyptus globulus Labill. | Antitussive |
| Eucalyptus globulus Labill. | Antiviral |
| Eucalyptus globulus Labill. | Astringent |
| Eucalyptus globulus Labill. | Bronchodilator |
| Eucalyptus globulus Labill. | Carminative |
| Eucalyptus globulus Labill. | Decongestant |
| Eucalyptus globulus Labill. | Deodorant |
| Eucalyptus globulus Labill. | Diuretic |
| Eucalyptus globulus Labill. | Expectorant |
| Eucalyptus globulus Labill. | Fungicide |
| Eucalyptus globulus Labill. | Hyperemic |
| Eucalyptus globulus Labill. | Hypoglycemic |
| Eucalyptus globulus Labill. | Insecticide |
| Eucalyptus globulus Labill. | Insectifuge |
| Eucalyptus globulus Labill. | Memorigenic |
| Eucalyptus globulus Labill. | Rubefacient |
| Eucalyptus globulus Labill. | Secretolytic |
| Eucalyptus globulus Labill. | Secretomotoric |
| Eucalyptus globulus Labill. | Sedative |
| Eucalyptus globulus Labill. | Sialagogue |
| Eucalyptus globulus Labill. | Stimulant |
| Eucalyptus globulus Labill. | Vermifuge |
Metabolite list (30)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005413
|
Rutin
/ Birutan / 3-Rutinosylquercetin / Quercetin 3-O-rutinoside / (+)-Quercetin 3-O-rutinoside / Quercetin 3-O-beta-rutinoside / (+)-Quercetin 3-O-beta-rutinoside / 3,3',4',5,7-Pentahydroxyflavone 3-rutinoside / Quercetin 3-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside |
CHEMBL32579
CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989 |
D012431
|
25 / 18 / 16 | 29 / 8 | No. 1 | No. 15 |
|
|
C00014075
|
8-C-Glucosylquercetin 2''-O-rhamnoside
|
No. 1 | No. 15 |
|
||||
|
C00005372
|
Hyperin
/ Hyperoside / Quercetin 3-O-galactoside / Quercetin 3-O-beta-D-galactoside / Quercetin 3-beta-galactopyranoside / Quercetin 3-O-beta-D-galactopyranoside |
CHEMBL33027
CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336 |
C021304
|
38 / 43 / 34 | 4 / 0 | No. 2 | No. 15 |
|
|
C00005374
|
Quercetin
|
CHEMBL82242
CHEMBL479232 CHEMBL1437696 |
C012526
|
14 / 2 / 2 | 2 / 1 | No. 2 | No. 15 |
|
|
C00001071
|
Myricetin
|
CHEMBL164
|
C040015
|
78 / 70 / 56 | 39 / 2 | No. 3 | No. 15 |
|
|
C00007190
|
(+)-Pinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
C103298
|
7 / 5 / 6 | No. 38 | No. 21 |
|
|
|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00000081
|
GA81
/ Gibberellin A81 |
No. 40 | No. 41 |
|
||||
|
C00000004
|
GA4
/ Gibberellin A4 |
No. 40 | No. 41 |
|
||||
|
C00000044
|
GA44
/ Gibberellin A44 |
No. 40 | No. 41 |
|
||||
|
C00000020
|
GA20
/ Gibberellin A20 |
No. 40 | No. 41 |
|
||||
|
C00000029
|
GA29
/ Gibberellin A29 |
No. 40 | No. 41 |
|
||||
|
C00000008
|
GA8
/ Gibberellin A8 |
No. 40 | No. 41 |
|
||||
|
C00013328
|
Tricetin
/ 5,7,3',4',5'-Pentahydroxyflavone / 5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL247484
|
C469689
|
20 / 20 / 26 | 2 / 0 | No. 71 | No. 15 |
|
|
C00000019
|
GA19
/ Gibberellin A19 |
C120175
|
No. 187 | No. 41 |
|
|||
|
C00021213
|
Globulol
/ (-)-Globulol |
CHEMBL2171207
|
1 / 2 / 3 | No. 197 | No. 38 |
|
||
|
C00000164
|
beta-Eudesmol
|
CHEMBL88244
|
C051082
|
No. 524 | No. 38 |
|
||
|
C00000163
|
alpha-Eudesmol
|
C118684
|
No. 524 | No. 38 |
|
|||
|
C00033838
|
Eucaglobulin
|
No. 810 |
|
|||||
|
C00033746
|
Cypellocarpin A
|
CHEMBL486175
|
No. 810 |
|
||||
|
C00033890
|
Globulusin B
/ (+)-Globulusin B |
No. 810 |
|
|||||
|
C00003053
|
(+-)-Pinocarvone
/ alpha-Pinocarvone |
No. 1561 | No. 35 |
|
||||
|
C00011043
|
(-)-Pinocarvone
|
No. 1561 | No. 35 |
|
||||
|
C00010802
|
1-Acetyl-4-isopropenylcyclopentene
/ 4-Isopropenyl-1-cyclopenten-1-yl methyl ketone |
No. 1740 | No. 35 |
|
||||
|
C00003039
|
Cuminaldehyde
/ Cuminyl aldehyde / 4-Isopropyl benzaldehyde |
CHEMBL161577
|
C007165
|
2 / 4 / 2 | No. 3751 | No. 35 |
|
|
|
C00002989
|
Euglobal-Ia1
|
CHEMBL454049
|
1 / 1 / 2 | No. 3849 |
|
|||
|
C00033737
|
Cuniloside
|
No. 4168 |
|
|||||
|
C00048366
|
Cuniloside B
/ (-)-Cuniloside B |
No. 4168 |
|
|||||
|
C00000136
|
1,8-Cineole
|
CHEMBL485259
CHEMBL1397305 |
99 / 57 / 50 | No. 5413 | No. 35 |
|
||
|
C00033889
|
Globulusin A
/ (+)-Globulusin A |
No. 5910 |
|
Human Protein / Gene in interactions
189 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000136 C00001071 C00005372 C00005413 C00013328 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001071 C00005372 C00005374 C00005413 C00013328 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001071 C00005372 C00005374 C00005413 C00013328 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000136 C00001071 C00005372 C00005413 C00007190 | 0 / 3 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001071 C00005372 C00005374 C00005413 C00013328 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000136 C00001071 C00005413 C00013328 | 0 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00001071 C00005372 C00005374 C00005413 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001071 C00005372 C00005374 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000136 C00001071 C00013328 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001071 C00005372 C00005413 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001071 C00005372 C00005374 | 1 / 1 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000136 C00005372 C00005413 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001071 C00005413 C00013328 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00001071 C00005372 C00005374 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001071 C00005372 C00005374 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00003039 C00005372 C00005413 | 4 / 2 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001071 C00005372 C00005374 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001071 C00005372 C00005413 | 1 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00001071 C00005372 C00005413 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001071 C00005374 C00013328 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000136 C00005372 C00005413 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001071 C00005413 C00013328 | 3 / 3 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000136 C00001071 C00005413 | 1 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00001071 C00005372 | 0 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001071 C00013328 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000136 C00005413 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001071 C00013328 | 2 / 2 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00005372 C00005413 | 2 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00005372 C00005413 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000136 C00001071 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000136 C00005372 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000136 C00005372 | 11 / 10 |
| P04062 | Glucosylceramidase | Enzyme | C00001071 C00005372 | 6 / 4 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000136 C00001071 | 1 / 1 |
| P06276 | Cholinesterase | Hydrolase | C00001071 C00005413 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001071 C00005374 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000136 C00001071 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000136 C00001071 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001071 C00013328 | 1 / 2 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001071 C00005374 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00001071 C00005372 | 3 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001071 C00005372 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00001071 C00005372 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00001071 C00013328 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001071 C00013328 | 2 / 5 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001071 C00005372 | 0 / 1 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000136 C00005372 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000136 C00005413 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000136 C00001071 | 0 / 1 |
| P07237 | Protein disulfide-isomerase | Enzyme | C00005372 C00005374 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00001071 C00013328 | 1 / 2 |
| O75496 | Geminin | Unclassified protein | C00000136 C00005372 | 0 / 0 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001071 C00005372 | 1 / 4 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00001071 C00005413 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00001071 C00005372 | 1 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000136 C00001071 | 1 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00001071 C00005413 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00001071 C00013328 | 2 / 3 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001071 C00013328 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00001071 C00013328 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000136 C00005372 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000136 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000136 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000136 | 0 / 0 |
| Q15746 | Myosin light chain kinase, smooth muscle | Mlck | C00001071 | 1 / 1 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000136 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000136 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000136 | 1 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000136 | 2 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000136 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000136 | 1 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001071 | 0 / 0 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00013328 | 4 / 4 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000136 | 1 / 8 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000136 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001071 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00001071 | 0 / 0 |
| P51570 | Galactokinase | Enzyme | C00013328 | 1 / 1 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000136 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000136 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000136 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000136 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000136 | 1 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000136 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000136 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000136 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000136 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000136 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000136 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000136 | 1 / 0 |
| Q14790 | Caspase-8 | C14 | C00001071 | 2 / 1 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000136 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000136 | 0 / 0 |
| P05121 | Plasminogen activator inhibitor 1 | Secreted protein | C00002989 | 1 / 2 |
| P27487 | Dipeptidyl peptidase 4 | S9B | C00005413 | 0 / 1 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000136 | 1 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00003039 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000136 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000136 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001071 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000136 | 0 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000136 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000136 | 1 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000136 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000136 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00001071 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000136 | 1 / 1 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000136 | 0 / 1 |
| P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00001071 | 5 / 4 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000136 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000136 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00001071 | 2 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000136 | 0 / 1 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000136 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000136 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000136 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000136 | 1 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001071 | 4 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000136 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000136 | 1 / 2 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000136 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000136 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000136 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00005372 | 1 / 1 |
| P04745 | Alpha-amylase 1 | Enzyme | C00001071 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00001071 | 2 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00000136 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00021213 | 2 / 3 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000136 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000136 | 3 / 2 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00001071 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000136 | 2 / 1 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00001071 | 0 / 1 |
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | C00000136 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001071 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000136 | 2 / 2 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001071 | 1 / 1 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001071 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000136 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000136 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000136 | 1 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000136 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000136 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000136 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000136 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000136 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000136 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000136 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000136 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00001071 | 0 / 0 |
| P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Enzyme | C00001071 | 9 / 1 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000136 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000136 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000136 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000136 | 0 / 0 |
| Q15046 | Lysine--tRNA ligase | Enzyme | C00001071 | 2 / 1 |
| P08246 | Neutrophil elastase | S1A | C00000136 | 2 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000136 | 2 / 2 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001071 | 0 / 0 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005372 | 1 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000136 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000136 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000136 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000136 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000136 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000136 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000136 | 0 / 1 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00001071 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000136 | 0 / 0 |
| P34949 | Mannose-6-phosphate isomerase | Enzyme | C00005372 | 1 / 1 |
| P48147 | Prolyl endopeptidase | S9A | C00005413 | 0 / 0 |
| Q7Z2W7 | Transient receptor potential cation channel subfamily M member 8 | Unclassified protein | C00000136 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001071 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001071 | 1 / 1 |
| P40225 | Thrombopoietin | Unclassified protein | C00001071 | 1 / 1 |
| P31941 | DNA dC->dU-editing enzyme APOBEC-3A | Enzyme | C00001071 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001071 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00005372 | 4 / 1 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00005372 | 0 / 0 |
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00005374 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001071 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001071 | 2 / 1 |
| Q9HCT0 | Fibroblast growth factor 22 | Unclassified protein | C00001071 | 0 / 0 |
59 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001071
C00005374
C00005413
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001071
C00005374
C00005413
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001071
C00005372
C00005413
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001071
C00005413
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00005413
C00013328
|
| 23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00001071
C00005372
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001071
C00005413
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00001071
C00005372
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00001071
C00005413
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001071
C00005413
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001071
C00005413
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001071
C00013328
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00001071
C00005413
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00001071
C00005413
|
| 8505 | PARG, PARG99 | poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) |
C00001071
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00001071
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00001071
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00001071
|
| 1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) |
C00001071
|
| 54583 | EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 | egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29) |
C00001071
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00001071
|
| 3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00001071
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00001071
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00001071
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00001071
|
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00001071
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00001071
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00001071
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00001071
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001071
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001071
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00001071
|
| 397 | ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 | Rho GDP dissociation inhibitor (GDI) beta |
C00001071
|
| 1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00001071
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00001071
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001071
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00001071
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00001071
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00001071
|
| 7161 | TP73, P73 | tumor protein p73 |
C00001071
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00005372
|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00005413
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00005413
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00005413
|
| 873 | CBR1, CBR, SDR21C1, hCBR1 | carbonyl reductase 1 (EC:1.1.1.189 1.1.1.197 1.1.1.184) |
C00005413
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00005413
|
| 3627 | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 | chemokine (C-X-C motif) ligand 10 |
C00005413
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00005413
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00005413
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00005413
|
| 3480 | IGF1R, CD221, IGFIR, IGFR, JTK13 | insulin-like growth factor 1 receptor (EC:2.7.10.1) |
C00005413
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00005413
|
| 3667 | IRS1, HIRS-1 | insulin receptor substrate 1 |
C00005413
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00005413
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00005413
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00005413
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00005413
|
| 7039 | TGFA, TFGA | transforming growth factor, alpha |
C00005413
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00005413
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (142)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613780 | Aortic aneurysm, familial thoracic 7; aat7 |
Q15746
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P42336
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #607271 | Caspase 8 deficiency |
Q14790
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib |
Q15046
|
| #114500 | Colorectal cancer; crc |
P18054
P42336 Q14191 |
| #602579 | Congenital disorder of glycosylation, type ib; cdg1b |
P34949
|
| #612918 | Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi |
P42336
|
| #615108 | Cowden syndrome 5; cws5 |
P42336
|
| #162800 | Cyclic neutropenia |
P08246
|
| #613916 | Deafness, autosomal recessive 89; dfnb89 |
Q15046
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #246200 | Donohue syndrome |
P06213
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P18054
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #230200 | Galactokinase deficiency |
P51570
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #114550 | Hepatocellular carcinoma |
P08581
P42336 |
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #182000 | Keratosis, seborrheic |
P42336
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 Q14790 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #602501 | Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap |
P42336
|
| #603387 | Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph |
P42336
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P42336 |
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
| #613329 | Plasminogen activator inhibitor-1 deficiency |
P05121
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #603903 | Sickle cell anemia |
P68871
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (108)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P08581 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P68871 (marker) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) Q15046 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
P42336 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P08581 (related) P35354 (related) |
| H00223 | Inherited thrombophilia |
P05121
(related)
|
| H01106 | Plasminogen activator inhibitor type 1 (PAI-1) deficiency |
P05121
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00719 | Leprechaunism |
P06213
(related)
|
| H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
| H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00021 | Renal cell carcinoma |
P08581
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H00032 | Thyroid cancer |
P27487
(marker)
P37231 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P28907
(marker)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00118 | Congenital disorders of glycosylation (CDG) type I |
P34949
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00070 | Galactosemia |
P51570
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H00020 | Colorectal cancer |
P68871
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00108 | Autoimmune lymphoproliferative syndromes (ALPS) |
Q14790
(related)
|
| H00801 | Familial thoracic aortic aneurysm and dissection (TAAD) |
Q15746
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
11 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D010146 | Pain |
C00005374
|
| D005909 | Glioblastoma |
C00001071
|
| D009203 | Myocardial Infarction |
C00001071
|
| D001424 | Bacterial Infections |
C00005413
|
| D003092 | Colitis |
C00005413
|
| D004409 | Dyskinesia, Drug-Induced |
C00005413
|
| D015212 | Inflammatory Bowel Diseases |
C00005413
|
| D007674 | Kidney Diseases |
C00005413
|
| D028361 | Mitochondrial Diseases |
C00005413
|
| D010243 | Paralysis |
C00005413
|
| D013276 | Stomach Ulcer |
C00005413
|