KCF-S cluster No. 1740 (6 metabolites)
Corresponding Phytochemical cluster No. 35
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 12 |
| rosids | 1 |
| eudicotyledons | 1 |
Cumulative family count
| class name | count |
|---|---|
| Lamiaceae | 6 |
| Ganodermataceae | 2 |
| Verbenaceae | 2 |
| Asteraceae | 2 |
| Apiaceae | 2 |
| Acaridae | 1 |
| Cyprinidae | 1 |
| Myrtaceae | 1 |
| Crassulaceae | 1 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Cyclic monoterpenes | 4 |
metabolites link (4)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Cyclic monoterpenes | C01767 | C00000807 |
| Cyclic monoterpenes | C02485 | C00000809 |
| Cyclic monoterpenes | C02289 | C00010890 |
| Cyclic monoterpenes | C11383 | C00010891 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00000807
|
(R)-(-)-Carvone
|
CHEMBL15676
CHEMBL501949 |
8 / 9 / 9 |
|
||
|
C00000809
|
(-)-Isopiperitenone
|
|
||||
|
C00010802
|
1-Acetyl-4-isopropenylcyclopentene
/ 4-Isopropenyl-1-cyclopenten-1-yl methyl ketone |
|
||||
|
C00010890
|
(+)-Isopiperitenone
/ p-Mentha-1,8-dien-3-one |
|
||||
|
C00010891
|
(S)-(+)-Carvone
|
CHEMBL15676
CHEMBL501949 |
8 / 9 / 9 |
|
||
|
C00035062
|
Carvone
|
CHEMBL15676
CHEMBL501949 |
C006923
|
8 / 9 / 9 | 5 / 2 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00000807 C00010891 C00035062 | 2 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000807 C00010891 C00035062 | 3 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000807 C00010891 C00035062 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000807 C00010891 C00035062 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000807 C00010891 C00035062 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00000807 C00010891 C00035062 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000807 C00010891 C00035062 | 1 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000807 C00010891 C00035062 | 1 / 1 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2554 | GABRA1, ECA4, EJM, EJM5 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
C00035062
|
| 2561 | GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
C00035062
|
| 2566 | GABRG2, CAE2, ECA2, GEFSP3 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
C00035062
|
| 387 | RHOA, ARH12, ARHA, RHO12, RHOH12 | ras homolog family member A |
C00035062
|
| 388 | RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 | ras homolog family member B |
C00035062
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (9)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|