Species

KNApSAcK Entry

Organism name Ephedra alata
Genus Ephedra
Family Ephedraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ephedra alata
Linked NCBI taxonomy ID 302006
Linked level species

Family

Family in NCBI taxonomy Ephedraceae
ID 3386

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00005337 External link 512 Herbacetin 7-glucoside
No. 2 No. 15
C00005364 External link 512 Sexangularetin 3-glucoside-7-rutinoside
No. 5 No. 15
C00002631 External link 512 (+)-Lirioresinol B
/ (+)-Syringaresinol
CHEMBL361362
CHEMBL402653
C042192
1 / 0 / 0 No. 38 No. 21
C00005938 External link 512 Herbacetin 7-(6''-quinoylglucoside)
No. 1511

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005374 1 / 1
P07237 Protein disulfide-isomerase Enzyme C00005374 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00002631 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00005374 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005374 0 / 0
P15121 Aldose reductase Enzyme C00005374 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005374 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005374 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00005374 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005374 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005374 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005374 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005374 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00005374

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (2)

KEGG name UniProt
H00192 Xanthinuria P47989 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D010146 Pain C00005374