Rhamnus disperma

• Index
• Plant Species
• Metabolite list (22)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Rhamnus disperma
Genus	Rhamnus
Family	Rhamnaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Rhamnus
Linked NCBI taxonomy ID	3609
Linked level	genus

Family

Family in NCBI taxonomy	Rhamnaceae
ID	3608

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (22)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00040131	Quercetin 3,4'-di-O-alpha-L-rhamnopyranoside					No. 1	No. 15
C00040151	Rhamnazin 3-O-robinoside					No. 1	No. 15
C00005401	Quercetin 3-robinoside / Quercetin 3-O-robinoside / Quercetin 3-O-robinobioside / Quercetin 3-O-rhamnosyl-(1->6)-galactoside	CHEMBL32579 CHEMBL310754 CHEMBL182108 CHEMBL226335 CHEMBL502782 CHEMBL1436093 CHEMBL1532989		25 / 18 / 16		No. 1	No. 15
C00005374	Quercetin	CHEMBL82242 CHEMBL479232 CHEMBL1437696	C012526	14 / 2 / 2	2 / 1	No. 2	No. 15
C00005381	Quercetin 7-galactoside / Quercetin 7-O-galactoside	CHEMBL248726				No. 2	No. 15
C00005372	Hyperin / Hyperoside / Quercetin 3-O-galactoside / Quercetin 3-O-beta-D-galactoside / Quercetin 3-beta-galactopyranoside / Quercetin 3-O-beta-D-galactopyranoside	CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336	C021304	38 / 43 / 34	4 / 0	No. 2	No. 15
C00005490	Quercetin 3-O-methyl 7-O-galactoside / Quercetin 3-methyl ether 3-galactoside	CHEMBL260805 CHEMBL574682		1 / 0 / 3		No. 2	No. 15
C00004632	Quercetin 3-methyl ether / Quercetin 3-O-methyl ether	CHEMBL163316		32 / 21 / 21		No. 3	No. 15
C00004567	Rhamnocitrin / 7-Methylkaempferol / 3,4',5-Trihydroxy-7-methoxyflavone / 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one	CHEMBL442289				No. 3	No. 15
C00004642	Rhamnazin / 7,3'-Di-O-methylquercetin / 3,4',5-Trihydroxy-3',7-dimethoxyflavone / 3,5-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one	CHEMBL457148				No. 3	No. 15
C00005253	Kaempferol 4'-rhamninoside / Kaempferol 4'-O-rhamninoside					No. 5	No. 15
C00005202	Kaempferol 3-rhamninoside / Kaempferol 3-O-rhamninoside					No. 5	No. 15
C00005611	Rhamnazin 3-rhamninoside / Rhamnazin 3-O-rhamninoside					No. 5	No. 15
C00040132	Quercetin 3-O-rhamninoside					No. 5	No. 15
C00005518	Rhamnetin 3-rhamninoside / Rhamnetin 3-O-rhamninoside	CHEMBL500372				No. 5	No. 15
C00040152	Rhamnocitrin 4'-O-rhamninoside					No. 5	No. 15
C00000960	Eriodictyol	CHEMBL8996 CHEMBL307893 CHEMBL1975989	C007619	32 / 29 / 55	5 / 0	No. 25	No. 14
C00000677	Distylin / Dihydroquercetin / (2R,3R)-Taxifolin	CHEMBL66 CHEMBL9249 CHEMBL337309 CHEMBL1492383	C003377	65 / 41 / 37	29 / 1	No. 42	No. 14
C00004565	Kaempferol / Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL150	C006552	76 / 69 / 87	86 / 8	No. 71	No. 15
C00002668	Protocatechuic acid / 3,4-Dihydroxybenzoic acid	CHEMBL37537	C009091	33 / 19 / 19	2 / 0	No. 817	No. 81
C00002648	Gentisic acid / 2,5-Dihydroxybenzoic acid	CHEMBL1461	C010925	15 / 6 / 8	2 / 1	No. 817	No. 81
C00039442	Isofraxetin					No. 864	No. 25

Human Protein / Gene in interactions

160 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UNA4	DNA polymerase iota	Enzyme	C00000677 C00000960 C00002648 C00002668 C00004565 C00004632 C00005372 C00005374	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000677 C00000960 C00002668 C00004565 C00004632 C00005372 C00005374 C00005401	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000677 C00000960 C00004565 C00004632 C00005372 C00005374 C00005401	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000677 C00000960 C00002668 C00004565 C00004632 C00005372 C00005401	4 / 3
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000677 C00000960 C00002668 C00004632 C00005372 C00005401	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00000677 C00000960 C00004565 C00004632 C00005372 C00005374	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000677 C00000960 C00004632 C00005372 C00005374 C00005401	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000677 C00000960 C00002668 C00004632 C00005372 C00005401	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000677 C00000960 C00004565 C00004632 C00005372 C00005374	1 / 1
O75496	Geminin	Unclassified protein	C00000677 C00000960 C00002668 C00004632 C00005372	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000960 C00002668 C00004632 C00005372 C00005374	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000677 C00004565 C00005372 C00005374 C00005401	1 / 1
P15121	Aldose reductase	Enzyme	C00002668 C00004565 C00004632 C00005372 C00005374	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000677 C00000960 C00004565 C00004632 C00005401	3 / 3
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000677 C00002648 C00002668 C00004565	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00004565 C00005372 C00005401 C00005490	0 / 3
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000677 C00000960 C00004565 C00005372	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000677 C00000960 C00004565 C00005401	0 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00000677 C00000960 C00005372 C00005401	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00000960 C00004565 C00004632 C00005374	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000677 C00000960 C00004632	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000677 C00000960 C00004565	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000677 C00000960 C00004632	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000677 C00005372 C00005401	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000960 C00004565 C00005374	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000677 C00002648 C00002668	2 / 2
P08254	Stromelysin-1	M10A	C00000677 C00002648 C00002668	1 / 0
P08253	72 kDa type IV collagenase	M10A	C00000677 C00002648 C00002668	1 / 3
O00255	Menin	Unclassified protein	C00000677 C00004565 C00004632	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000677 C00004565 C00004632	1 / 2
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004565 C00005372 C00005401	2 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000677 C00000960 C00004565	2 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000677 C00002668 C00005372	0 / 1
P03372	Estrogen receptor	NR3A1	C00002668 C00004565 C00005401	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000677 C00004632 C00005372	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000677 C00002668 C00005372	1 / 4
P03956	Interstitial collagenase	M10A	C00000677 C00002648 C00002668	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00004632 C00005372 C00005401	1 / 0
P14679	Tyrosinase	Oxidoreductase	C00004565 C00005372 C00005401	4 / 2
P22303	Acetylcholinesterase	Hydrolase	C00000960 C00004565 C00005401	1 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000677 C00000960 C00004565	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000677 C00004565	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005372 C00005374	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000677 C00005372	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000677 C00004565	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00000677 C00004632	1 / 2
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000960 C00004565	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005372 C00005401	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002648 C00002668	1 / 2
P11388	DNA topoisomerase 2-alpha	Isomerase	C00004565 C00005401	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00004565 C00004632	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000677 C00005372	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00004565 C00005372	11 / 10
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00004565 C00005401	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000960 C00004565	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002648 C00002668	0 / 0
P48147	Prolyl endopeptidase	S9A	C00004565 C00005401	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002648 C00002668	0 / 1
O43570	Carbonic anhydrase 12	Lyase	C00002648 C00002668	1 / 2
P22894	Neutrophil collagenase	M10A	C00002648 C00002668	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000677 C00004565	1 / 1
P43166	Carbonic anhydrase 7	Lyase	C00002648 C00002668	0 / 0
P04062	Glucosylceramidase	Enzyme	C00004565 C00005372	6 / 4
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000960 C00005372	0 / 1
Q99700	Ataxin-2	Unclassified protein	C00004565 C00004632	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00000677 C00005372	4 / 1
P41143	Delta-type opioid receptor	Opioid receptor	C00000677 C00005372	0 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00004565 C00005372	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002648 C00002668	0 / 0
P06276	Cholinesterase	Hydrolase	C00004565 C00005401	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00004565 C00005401	0 / 1
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000960 C00004565	4 / 4
P04637	Cellular tumor antigen p53	Transcription Factor	C00000960 C00004565	7 / 37
P33527	Multidrug resistance-associated protein 1	drugs	C00004565 C00005401	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000960 C00005372	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000960 C00005372	3 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002668 C00005374	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000677 C00002648	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00004565 C00004632	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000677 C00004565	1 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00000960 C00004632	2 / 1
P04150	Glucocorticoid receptor	NR3C1	C00004565	0 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00004632	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00004565	5 / 3
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00004565	1 / 1
P07711	Cathepsin L1	C1A	C00002668	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00005372	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00004565	0 / 0
P45452	Collagenase 3	M10A	C00000677	1 / 1
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00000677	2 / 0
Q96RI1	Bile acid receptor	NR1H4	C00004565	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00005401	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00004632	2 / 0
P56817	Beta-secretase 1	A1A	C00000677	0 / 0
P42858	Huntingtin	Unclassified protein	C00004632	1 / 1
P16581	E-selectin	Adhesion	C00002668	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00004565	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002668	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00004565	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00000677	1 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00004565	1 / 8
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000677	5 / 2
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00004565	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00004632	0 / 0
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00004565	0 / 0
P04792	Heat shock protein beta-1	Unclassified protein	C00004632	2 / 1
Q9GZT9	Egl nine homolog 1	Enzyme	C00002668	1 / 1
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000677	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00004565	0 / 0
P14151	L-selectin	Adhesion	C00002668	0 / 0
P16109	P-selectin	Adhesion	C00002668	1 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00004565	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00004565	0 / 0
P08183	Multidrug resistance protein 1	drug	C00004565	1 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00004565	1 / 1
P11309	Serine/threonine-protein kinase pim-1	Pim	C00004565	0 / 0
P02768	Serum albumin	Secreted protein	C00002668	0 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00004565	1 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00004632	0 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00004565	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000677	0 / 1
P10275	Androgen receptor	NR3C4	C00004565	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00004565	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00004565	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00004565	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000677	0 / 0
P34949	Mannose-6-phosphate isomerase	Enzyme	C00005372	1 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00004565	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002668	1 / 1
P39900	Macrophage metalloelastase	M10A	C00000677	0 / 0
P24298	Alanine aminotransferase 1	Enzyme	C00000677	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00002668	3 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000677	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00004565	2 / 2
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00004565	1 / 1
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00004632	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000677	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00000960	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00000677	2 / 0
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00005374	0 / 0
Q05513	Protein kinase C zeta type	Iota	C00000677	0 / 0
Q04759	Protein kinase C theta type	Delta	C00000677	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00000677	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00000677	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000677	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000677	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00000677	1 / 1
P05771	Protein kinase C beta type	Alpha	C00000677	0 / 0
P24723	Protein kinase C eta type	Eta	C00000677	1 / 0
P41743	Protein kinase C iota type	Iota	C00000677	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000677	0 / 0
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00004565	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00004565	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00004565	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00004565	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00004565	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00004565	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002648	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00004565	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00005372	1 / 0

117 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000677 C00000960 C00004565
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000677 C00000960 C00004565
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00004565 C00005372
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00004565 C00005374
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00004565 C00005374
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00004565 C00005372
581	BAX, BCL2L4	BCL2-associated X protein	C00004565 C00005372
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000960 C00004565
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000677 C00004565
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000677 C00004565
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000677 C00000960
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00004565
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00000677
2621	GAS6, AXLLG, AXSF	growth arrest-specific 6	C00000677
2248	FGF3, HBGF-3, INT2	fibroblast growth factor 3	C00000677
3458	IFNG, IFG, IFI	interferon, gamma	C00000677
8817	FGF18, FGF-18, ZFGF5	fibroblast growth factor 18	C00000677
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000677
4547	MTTP, ABL, MTP	microsomal triglyceride transfer protein	C00000677
1950	EGF, HOMG4, URG	epidermal growth factor	C00000677
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000677
5155	PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis	platelet-derived growth factor beta polypeptide	C00000677
5921	RASA1, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	C00000677
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000677
7187	TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1	TNF receptor-associated factor 3	C00000677
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000677
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00000677
7507	XPA, XP1, XPAC	xeroderma pigmentosum, complementation group A	C00000677
7518	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	C00000677
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004565
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004565
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00004565
239	ALOX12, 12-LOX, 12S-LOX, LOG12	arachidonate 12-lipoxygenase (EC:1.13.11.31)	C00004565
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00004565
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00004565
1630	DCC, CRC18, CRCR1, IGDCC1, MRMV1	deleted in colorectal carcinoma	C00000677
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00004565
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00004565
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00004565
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00004565
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00004565
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00004565
891	CCNB1, CCNB	cyclin B1	C00004565
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00004565
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00004565
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00004565
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00004565
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00004565
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00004565
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00004565
37618			C00004565
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00000677
993	CDC25A, CDC25A2	cell division cycle 25A (EC:3.1.3.48)	C00000677
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00004565
8900	CCNA1	cyclin A1	C00000677
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00004565
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00004565
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00004565
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00000677
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004565
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00004565
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00004565
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00004565
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00004565
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00004565
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00004565
335	APOA1	apolipoprotein A-I	C00000677
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00004565
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00004565
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00004565
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00004565
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00004565
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00004565
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00004565
4297	KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS	lysine (K)-specific methyltransferase 2A (EC:2.1.1.43)	C00004565
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00004565
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00004565
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00004565
110357			C00004565
4502	MT2A, MT2	metallothionein 2A	C00004565
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00004565
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00004565
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00004565
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00004565
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00004565
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00004565
5241	PGR, NR3C3, PR	progesterone receptor	C00004565
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00000677
8000	PSCA, PRO232	prostate stem cell antigen	C00004565
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00004565
6119	RPA3, REPA3	replication protein A3, 14kDa	C00004565
2810	SFN, YWHAS	stratifin	C00004565
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00004565
6773	STAT2, ISGF-3, P113, STAT113	signal transducer and activator of transcription 2, 113kDa	C00004565
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00004565
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004565
7039	TGFA, TFGA	transforming growth factor, alpha	C00004565
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00004565
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00004565
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00004565
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00004565
7161	TP73, P73	tumor protein p73	C00004565
7352	UCP3, SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	C00004565
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00004565
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00004565
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00004565
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00004565
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00004565
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00004565
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00004565
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00004565
29110	TBK1, NAK, T2K	TANK-binding kinase 1 (EC:2.7.11.1)	C00000960
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00002668
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00002668
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00002648
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002648
23411	SIRT1, SIR2L1	sirtuin 1	C00005372

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