| Organism name | Artemisia capillaris | 
|---|---|
| Genus | Artemisia | 
| Family | Asteraceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Artemisia capillaris | 
|---|---|
| Linked NCBI taxonomy ID | 265783 | 
| Linked level | species | 
| Family in NCBI taxonomy | Asteraceae | 
|---|---|
| ID | 4210 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00005374   | Quercetin | CHEMBL82242 CHEMBL479232 CHEMBL1437696 | C012526 | 14 / 2 / 2 | 2 / 1 | No. 2 | No. 15 |   | 
| C00003938   | Arcapillin | No. 3 | No. 15 |   | ||||
| C00002420   | Capillarisin | C011185 | No. 3 | No. 15 |   | |||
| C00001043   | Genkwanin | CHEMBL210635 | C014568 | 5 / 4 / 5 | 3 / 0 | No. 3 | No. 15 |   | 
| C00000601   | (+)-Sesamin | CHEMBL43469 CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861 | C054125 | 20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 |   | 
| C00000330   | Capillarin | CHEMBL479330 | 2 / 0 / 0 | No. 1865 |   | |||
| C00000327   | Capillarol | No. 2545 |   | |||||
| C00000328   | Capillin | C065814 | No. 2791 |   | ||||
| C00000329   | Capillen | No. 2791 |   | |||||
| C00049129   | Capillaridin E | No. 2791 |   | |||||
| C00049126   | Capillaridin B | No. 2791 |   | |||||
| C00049130   | Capillaridin F | No. 3503 |   | |||||
| C00049131   | Capillaridin G | No. 3503 |   | |||||
| C00049132   | Capillaridin H | No. 3503 |   | |||||
| C00049127   | Capillaridin C | No. 4403 |   | |||||
| C00049128   | Capillaridin D | No. 4403 |   | |||||
| C00049125   | Capillaridin A | No. 7008 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000330 C00000601 | 0 / 0 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 C00005374 | 0 / 0 | 
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 | 1 / 0 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00005374 | 1 / 1 | 
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001043 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 | 0 / 1 | 
| P07237 | Protein disulfide-isomerase | Enzyme | C00005374 | 0 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 | 2 / 3 | 
| Q9Y3R4 | Sialidase-2 | Enzyme | C00001043 | 0 / 0 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00005374 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00005374 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 | 2 / 0 | 
| O75496 | Geminin | Unclassified protein | C00000601 | 0 / 0 | 
| P15121 | Aldose reductase | Enzyme | C00005374 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 | 7 / 3 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00005374 | 1 / 1 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00005374 | 0 / 0 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 | 4 / 1 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 | 0 / 0 | 
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001043 | 4 / 4 | 
| P04745 | Alpha-amylase 1 | Enzyme | C00001043 | 0 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 | 0 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 | 2 / 2 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 | 0 / 1 | 
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00005374 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00005374 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00005374 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 | 0 / 0 | 
| P06239 | Tyrosine-protein kinase Lck | Src | C00001043 | 0 / 1 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00005374 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00005374 | 0 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000330 | 0 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00005374 | 0 / 0 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 | 1 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00001043
                          C00005374 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00001043
                          C00005374 | 
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | C00001043 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137750 | Glaucoma 1, open angle, a; glc1a | Q16678 | 
| #231300 | Glaucoma 3, primary congenital, a; glc3a | Q16678 | 
| #137760 | Glaucoma, primary open angle; poag | Q16678 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #604229 | Peters anomaly | Q16678 | 
| #172700 | Pick disease of brain | P10636 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #253300 | Spinal muscular atrophy, type i; sma1 | Q16637 | 
| #253550 | Spinal muscular atrophy, type ii; sma2 | Q16637 | 
| #253400 | Spinal muscular atrophy, type iii; sma3 | Q16637 | 
| #271150 | Spinal muscular atrophy, type iv; sma4 | Q16637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| #278300 | Xanthinuria, type i | P47989 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00093 | Combined immunodeficiencies (CIDs) | P06239
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) Q13148 (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00455 | Spinal muscular atrophy (SMA) | Q16637
                            (related) | 
| H00612 | Primary open angle glaucoma | Q16678
                            (related) | 
| H01075 | Peters anomaly | Q16678
                            (related) | 
| H01159 | Anterior segment dysgenesis (ASD) | Q16678
                            (related) | 
| H01203 | Primary congenital glaucoma (PCG) | Q16678
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) |